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Human and Clinical Nutrition Commons

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University of Arkansas, Fayetteville

Theses/Dissertations

Caco-2

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Full-Text Articles in Human and Clinical Nutrition

Bioavailability Of Bioactive Compounds, Wing Shun Lam Aug 2018

Bioavailability Of Bioactive Compounds, Wing Shun Lam

Graduate Theses and Dissertations

Arachidin-1 (Ara-1) and arachidin-3 (Ara-3) are stilbenoids found in hairy peanut roots, which have been shown to possess similar, if not higher, efficacy in biological activities when compared to nonprenylated analogs such as piceatannol and resveratrol. Blackberry essences are concentrated volatiles, which are characterized by low molecular weight, lipophilic properties, and have also been demonstrated to have health benefits. As interest in dietary bioactive compounds functional ingredients increase, more emphasis has been placed on identifying which compounds have high efficacy as well as bioavailability. The ability of a compound to exert its health promoting effects depends on its bioavailable dose, …


Antiproliferative Activity Of Carotenoids, Phenolic Compounds, And Volatile Terpenoids In Carrots (Daucus Carota L.), Brittany Frederick May 2018

Antiproliferative Activity Of Carotenoids, Phenolic Compounds, And Volatile Terpenoids In Carrots (Daucus Carota L.), Brittany Frederick

Graduate Theses and Dissertations

Epidemiological studies have shown an association between high carrot consumption and low prevalence of cancer. This observation has been thought to be attributed to carrot carotenoids. Despite this, various intervention trials have displayed no changes in incidence or increased incidence of cancer with carotenoid supplementation. It is possible that carrot phenolics are responsible for this association, though this has not been widely accepted. Volatile terpenoids from carrots have not been studied in this regard. Therefore, the primary objective of this study was to compare the antiproliferative effects of carotenoids, phenolics, and volatile terpenoids extracted from carrots on Caco-2 colon cancer …