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Articles 1 - 12 of 12
Full-Text Articles in Behavioral Neurobiology
Enhanced Nicotine Self-Administration And Suppressed Dopaminergic Systems In A Rat Model Of Diabetes, Laura O'Dell
Enhanced Nicotine Self-Administration And Suppressed Dopaminergic Systems In A Rat Model Of Diabetes, Laura O'Dell
Laura Elena O'Dell
Patients with diabetes display a heightened propensity to use tobacco; however, it is unclear whether they experience enhanced rewarding effects of nicotine. Thus, this study examined the reinforcing effects of nicotine in a rodent model of diabetes involving administration of streptozotocin (STZ), a drug that is toxic to pancreatic insulin-producing cells. The first study compared STZ- and vehicle-treated rats that had 23-hour access to intravenous self-administration (IVSA) of nicotine or saline and concomitant access to food and water. In order to examine the contribution of dopamine to our behavioral effects, dopamine transporter (DAT), D1 and D2 receptor levels were compared …
Behavioral, Biochemical, And Molecular Indices Of Stress Are Enhanced In Female Versus Male Rats Experiencing Nicotine Withdrawal, Laura O'Dell
Laura Elena O'Dell
Stress is a major factor that promotes tobacco use and relapse during withdrawal. Although women are more vulnerable to tobacco use than men, the manner in which stress contributes to tobacco use in women versus men is unclear.Thus, the goal of this study was to compare behavioral and biological indices of stress in male and female rats during nicotine withdrawal. Since the effects of nicotine withdrawal are age-dependent, this study also included adolescent rats. An initial study was conducted to provide comparable nicotine doses across age and sex during nicotine exposure and withdrawal. Rats received sham surgery or an osmotic …
Effect Of Nicotine On Body Composition, Laura O'Dell
Effect Of Nicotine On Body Composition, Laura O'Dell
Laura Elena O'Dell
No abstract provided.
Female Rats Display Dose-Dependent Differences To The Rewarding And Aversive Effects Of Nicotine In An Age-, Hormone-, And Sex-Dependent Manner., Laura O'Dell
Laura Elena O'Dell
No abstract provided.
Nicotine Withdrawal Produces Fewer Decreases In Extracellular Levels Of Dopamine In The Nucleus Accumbens Of Adolescent Versus Adult Rats., Laura O'Dell
Laura Elena O'Dell
No abstract provided.
Enhanced Vulnerability To The Rewarding Effects Of Nicotine During The Adolescent Period Of Development, Laura O'Dell
Enhanced Vulnerability To The Rewarding Effects Of Nicotine During The Adolescent Period Of Development, Laura O'Dell
Laura Elena O'Dell
No abstract provided.
Adolescent Nicotine Exposure Produces Less Affective Measures Of Withdrawal Relative To Adult Nicotine Exposure In Male Rats, Laura O'Dell
Adolescent Nicotine Exposure Produces Less Affective Measures Of Withdrawal Relative To Adult Nicotine Exposure In Male Rats, Laura O'Dell
Laura Elena O'Dell
No abstract provided.
“Nicotine Deprivation Effect” In Rats With Intermittent 23-Hour Access To Intravenous Nicotine Self-Administration, Laura O'Dell
“Nicotine Deprivation Effect” In Rats With Intermittent 23-Hour Access To Intravenous Nicotine Self-Administration, Laura O'Dell
Laura Elena O'Dell
No abstract provided.
Diminished Nicotine Withdrawal In Adolescent Rats: Implications For Vulnerability To Addiction, Laura O'Dell
Diminished Nicotine Withdrawal In Adolescent Rats: Implications For Vulnerability To Addiction, Laura O'Dell
Laura Elena O'Dell
No abstract provided.
Crf–Crf1 System Activation Mediates Withdrawal-Induced Increases In Nicotine Self-Administration In Nicotine-Dependent Rats., Laura O'Dell
Crf–Crf1 System Activation Mediates Withdrawal-Induced Increases In Nicotine Self-Administration In Nicotine-Dependent Rats., Laura O'Dell
Laura Elena O'Dell
No abstract provided.
Extended Access To Nicotine Self-Administration Leads To Dependence: Circadian Measures, Withdrawal Measures, And Extinction Behavior In Rats, Laura O'Dell
Laura Elena O'Dell
No abstract provided.
Diminished Nicotine Withdrawal In Adolescent Rats: Implications For Vulnerability To Addiction, Laura O'Dell
Diminished Nicotine Withdrawal In Adolescent Rats: Implications For Vulnerability To Addiction, Laura O'Dell
Laura Elena O'Dell
No abstract provided.