Behavioral Neurobiology Commons^™

Neural Substrates Of Sound–Touch Synesthesia After A Thalamic Lesion, Michael S. Beauchamp, Tony Ro

Publications and Research

Neural plasticity induced by stroke can mediate positive outcomes, such as recovery of function, but can also result in the formation of abnormal connections with negative consequences for perception and cognition. In three experiments using blood-oxygen level dependent (BOLD) functional magnetic resonance imaging, we examined the neural substrates of acquired auditory-tactile synesthesia, in which certain sounds can produce an intense somatosensory tingling sensation in a patient with a thalamic lesion. Compared with nine normal controls, the first experiment showed that the patient had a threefold greater BOLD response to sounds in the parietal operculum, the location of secondary somatosensory cortex. …

Effects Of Pre-Pubertal Social Experiences On The Responsiveness Of Juvenile Rats To Predator Odors, Stephen M. Siviy

Psychology Faculty Publications

The extent to which social variables may modulate the fear associated with a predator cue was assessed in juvenile rats. Cat odor reduced play to a comparable extent in both socially housed and isolate-housed rats, although socially housed rats exhibited more risk assessment during extinction. Rats that had played previously in the context used for assessing fear hid slightly less when exposed to cat odor than those rats that had not played previously in the testing context. However, no other differences were found between these two groups suggesting that prior social experience with the testing context has minimal effects on …

The Development Of Day-Night Differences In Sleep And Wakefulness In Norway Rats And The Effect Of Bilateral Enucleation, Andrew J. Gall, William D. Todd, Baisali Ray, Cassandra M. Coleman, Mark S. Blumberg

Faculty Publications

The suprachiasmatic nucleus (SCN) exhibits circadian rhythmicity in fetal and infant rats, but little is known about the consequences of this rhythmicity for infant behavior. Here, in Experiment 1, we measured sleep and wakefulness in rats during the day and night in postnatal day (P)2, P8, P15 and P21 subjects. As early as P2, day-night differences in sleep-wake activity were detected. Nocturnal wakefulness began to emerge around P15 and was reliably expressed by P21. We hypothesized that the process of photic entrainment over the first postnatal week, which depends upon the development of connectivity between the retinohypothalamic tract (RHT) and …

The Parallel Worm Tracker: A Platform For Measuring Average Speed And Drug-Induced Paralysis In Nematodes, Daniel Ramot, Brandon E. Johnson, Tommie L. Berry Jr., Lucinda Carnell, Miriam B. Goodman

All Faculty Scholarship for the College of the Sciences

Background

Caenorhabditis elegans locomotion is a simple behavior that has been widely used to dissect genetic components of behavior, synaptic transmission, and muscle function. Many of the paradigms that have been created to study C. elegans locomotion rely on qualitative experimenter observation. Here we report the implementation of an automated tracking system developed to quantify the locomotion of multiple individual worms in parallel.

Methodology/Principal Findings

Our tracking system generates a consistent measurement of locomotion that allows direct comparison of results across experiments and experimenters and provides a standard method to share data between laboratories. The tracker utilizes a video camera …

Cross-Modal Interaction Between Vision And Hearing: A Speed—Accuracy Analysis, Yoav Arieh, Lawrence E. Marks

Department of Psychology Faculty Scholarship and Creative Works

Cross-modal facilitation of response time (RT) is said to occur in a selective attention task when the introduction of an irrelevant sound increases the speed at which visual stimuli are detected and identified. To investigate the source of the facilitation in RT, we asked participants to rapidly identify the color of lights in the quiet and when accompanied by a pulse of noise. The resulting measures of accuracy and RT were used to derive speed-accuracy trade-off functions (SATFs) separately for the noise and the no-noise conditions. The two resulting SATFs have similar slopes and intercepts and, thus, can be treated …

Effects Of Neonatal Handling On Play Behavior And Fear Towards A Predator Odor In Juvenile Rats, Stephen M. Siviy

Psychology Faculty Publications

The effects of brief daily separation, also known as "handling," during the first 2 weeks of life on play behavior and fearfulness toward a predatory odor were assessed in juvenile rats. Handled rats were more playful than nonhandled control rats, and while handling had no effect on the direct response of these rats toward a predatory odor, handled rats did not exhibit a conditioned suppression of play when tested later in the same context where they had been exposed to the predatory odor. Handled rats were still wary of the environment in that they continued to show a heightened level …

Crf1 Receptor Antagonists Attenuate Escalated Cocaine Self-Administration In Rats, Laura O'Dell

Laura Elena O'Dell

No abstract provided.

Cellular And Behavioral Interactions Of Gabapentin With Alcohol Dependence, Laura O'Dell

Laura Elena O'Dell

No abstract provided.

Enhanced Vulnerability To The Rewarding Effects Of Nicotine During The Adolescent Period Of Development, Laura O'Dell

Laura Elena O'Dell

No abstract provided.