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Full-Text Articles in Behavioral Neurobiology

Enhanced Nicotine Self-Administration And Suppressed Dopaminergic Systems In A Rat Model Of Diabetes, Laura O'Dell Jul 2013

Enhanced Nicotine Self-Administration And Suppressed Dopaminergic Systems In A Rat Model Of Diabetes, Laura O'Dell

Laura Elena O'Dell

Patients with diabetes display a heightened propensity to use tobacco; however, it is unclear whether they experience enhanced rewarding effects of nicotine. Thus, this study examined the reinforcing effects of nicotine in a rodent model of diabetes involving administration of streptozotocin (STZ), a drug that is toxic to pancreatic insulin-producing cells. The first study compared STZ- and vehicle-treated rats that had 23-hour access to intravenous self-administration (IVSA) of nicotine or saline and concomitant access to food and water. In order to examine the contribution of dopamine to our behavioral effects, dopamine transporter (DAT), D1 and D2 receptor levels were compared …


Behavioral, Biochemical, And Molecular Indices Of Stress Are Enhanced In Female Versus Male Rats Experiencing Nicotine Withdrawal, Laura O'Dell Apr 2013

Behavioral, Biochemical, And Molecular Indices Of Stress Are Enhanced In Female Versus Male Rats Experiencing Nicotine Withdrawal, Laura O'Dell

Laura Elena O'Dell

Stress is a major factor that promotes tobacco use and relapse during withdrawal. Although women are more vulnerable to tobacco use than men, the manner in which stress contributes to tobacco use in women versus men is unclear.Thus, the goal of this study was to compare behavioral and biological indices of stress in male and female rats during nicotine withdrawal. Since the effects of nicotine withdrawal are age-dependent, this study also included adolescent rats. An initial study was conducted to provide comparable nicotine doses across age and sex during nicotine exposure and withdrawal. Rats received sham surgery or an osmotic …


Effect Of Nicotine On Body Composition, Laura O'Dell May 2012

Effect Of Nicotine On Body Composition, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Nico-Teen: Neural Substrates That Mediate Adolescent Tobacco Abuse., Laura O'Dell Dec 2010

Nico-Teen: Neural Substrates That Mediate Adolescent Tobacco Abuse., Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Nico-Teen: Neural Substrates That Mediate Adolescent Tobacco Abuse., Laura O'Dell Dec 2010

Nico-Teen: Neural Substrates That Mediate Adolescent Tobacco Abuse., Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Impact Of Serotonin 2c Receptor Null Mutation On Physiology And Behavior Associated With Nigrostriatal Dopamine Pathway Function., Laura O'Dell Jan 2009

Impact Of Serotonin 2c Receptor Null Mutation On Physiology And Behavior Associated With Nigrostriatal Dopamine Pathway Function., Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Alcohol Self-Administration Acutely Stimulates The Hypothalamic-Pituitary-Adrenal (Hpa) Axis, But Alcohol Dependence Leads To A Dampened Neuroendocrine State, Laura O'Dell Jan 2009

Alcohol Self-Administration Acutely Stimulates The Hypothalamic-Pituitary-Adrenal (Hpa) Axis, But Alcohol Dependence Leads To A Dampened Neuroendocrine State, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Female Rats Display Dose-Dependent Differences To The Rewarding And Aversive Effects Of Nicotine In An Age-, Hormone-, And Sex-Dependent Manner., Laura O'Dell Jan 2009

Female Rats Display Dose-Dependent Differences To The Rewarding And Aversive Effects Of Nicotine In An Age-, Hormone-, And Sex-Dependent Manner., Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Rodent Models Of Nicotine Reward: What Do They Tell Us About Tobacco Abuse In Humans?, Laura O'Dell Jan 2009

Rodent Models Of Nicotine Reward: What Do They Tell Us About Tobacco Abuse In Humans?, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Nicotine Withdrawal Produces Fewer Decreases In Extracellular Levels Of Dopamine In The Nucleus Accumbens Of Adolescent Versus Adult Rats., Laura O'Dell Jan 2009

Nicotine Withdrawal Produces Fewer Decreases In Extracellular Levels Of Dopamine In The Nucleus Accumbens Of Adolescent Versus Adult Rats., Laura O'Dell

Laura Elena O'Dell

No abstract provided.


A Psychobiological Framework Of The Substrates That Mediate Nicotine Use During Adolescence, Laura O'Dell Jan 2009

A Psychobiological Framework Of The Substrates That Mediate Nicotine Use During Adolescence, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Protracted Withdrawal From Alcohol And Drugs Of Abuse Impairs Long-Term Potentiation Of Intrinsic Excitability In The Juxtacapsular Bed Nucleus Of The Stria Terminalis, Laura O'Dell Dec 2008

Protracted Withdrawal From Alcohol And Drugs Of Abuse Impairs Long-Term Potentiation Of Intrinsic Excitability In The Juxtacapsular Bed Nucleus Of The Stria Terminalis, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


The Effects Of Opioids And Opioid Analogs On Animal And Human Endocrine Systems, Laura O'Dell Dec 2008

The Effects Of Opioids And Opioid Analogs On Animal And Human Endocrine Systems, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Pdf Of All O'Dell Manuscripts, Laura O'Dell Dec 2008

Pdf Of All O'Dell Manuscripts, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Crf1 Receptor Antagonists Attenuate Escalated Cocaine Self-Administration In Rats, Laura O'Dell Jan 2008

Crf1 Receptor Antagonists Attenuate Escalated Cocaine Self-Administration In Rats, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Cellular And Behavioral Interactions Of Gabapentin With Alcohol Dependence, Laura O'Dell Jan 2008

Cellular And Behavioral Interactions Of Gabapentin With Alcohol Dependence, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Enhanced Vulnerability To The Rewarding Effects Of Nicotine During The Adolescent Period Of Development, Laura O'Dell Jan 2008

Enhanced Vulnerability To The Rewarding Effects Of Nicotine During The Adolescent Period Of Development, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Adolescent Nicotine Exposure Produces Less Affective Measures Of Withdrawal Relative To Adult Nicotine Exposure In Male Rats, Laura O'Dell Jan 2007

Adolescent Nicotine Exposure Produces Less Affective Measures Of Withdrawal Relative To Adult Nicotine Exposure In Male Rats, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


“Nicotine Deprivation Effect” In Rats With Intermittent 23-Hour Access To Intravenous Nicotine Self-Administration, Laura O'Dell Jan 2007

“Nicotine Deprivation Effect” In Rats With Intermittent 23-Hour Access To Intravenous Nicotine Self-Administration, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Diminished Nicotine Withdrawal In Adolescent Rats: Implications For Vulnerability To Addiction, Laura O'Dell Jan 2007

Diminished Nicotine Withdrawal In Adolescent Rats: Implications For Vulnerability To Addiction, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Viral Vector-Induced Amygdala Npy Overexpression Reverses Increased Alcohol Intake Caused By Repeated Deprivations In Wistar Rats, Laura O'Dell Jan 2007

Viral Vector-Induced Amygdala Npy Overexpression Reverses Increased Alcohol Intake Caused By Repeated Deprivations In Wistar Rats, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Crf–Crf1 System Activation Mediates Withdrawal-Induced Increases In Nicotine Self-Administration In Nicotine-Dependent Rats., Laura O'Dell Jan 2007

Crf–Crf1 System Activation Mediates Withdrawal-Induced Increases In Nicotine Self-Administration In Nicotine-Dependent Rats., Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Behavioral And Neurochemical Responses To Cocaine In Periadolescent And Adult Rats, Laura O'Dell Jan 2006

Behavioral And Neurochemical Responses To Cocaine In Periadolescent And Adult Rats, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Extended Access To Nicotine Self-Administration Leads To Dependence: Circadian Measures, Withdrawal Measures, And Extinction Behavior In Rats, Laura O'Dell Jan 2006

Extended Access To Nicotine Self-Administration Leads To Dependence: Circadian Measures, Withdrawal Measures, And Extinction Behavior In Rats, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Corticotropin-Releasing Factor Within The Central Nucleus Of The Amygdala Mediates Enhanced Ethanol Self-Administration In Ethanol-Dependent Rats During Withdrawal., Laura O'Dell Jan 2006

Corticotropin-Releasing Factor Within The Central Nucleus Of The Amygdala Mediates Enhanced Ethanol Self-Administration In Ethanol-Dependent Rats During Withdrawal., Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Biphasic Alterations In Serotonin1b (5-Ht1b) Receptor Function During Abstinence From Extended Cocaine Self-Administration, Laura O'Dell Jan 2006

Biphasic Alterations In Serotonin1b (5-Ht1b) Receptor Function During Abstinence From Extended Cocaine Self-Administration, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Diminished Nicotine Withdrawal In Adolescent Rats: Implications For Vulnerability To Addiction, Laura O'Dell Jan 2006

Diminished Nicotine Withdrawal In Adolescent Rats: Implications For Vulnerability To Addiction, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Unlimited Access To Heroin Self-Administration: Independent Motivational Markers Of Opiate Dependence, Laura O'Dell Jan 2006

Unlimited Access To Heroin Self-Administration: Independent Motivational Markers Of Opiate Dependence, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Stress Enhancement Of Craving During Sobriety: A Risk For Relapse, Laura O'Dell Jan 2005

Stress Enhancement Of Craving During Sobriety: A Risk For Relapse, Laura O'Dell

Laura Elena O'Dell

No abstract provided.


Epipregnanolone And A Novel Synthetic Neuroactive Steroid Reduce Reduce Alcohol Self-Administration In Rats., Laura O'Dell Jan 2005

Epipregnanolone And A Novel Synthetic Neuroactive Steroid Reduce Reduce Alcohol Self-Administration In Rats., Laura O'Dell

Laura Elena O'Dell

No abstract provided.