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Articles 91 - 97 of 97

Full-Text Articles in Neuroscience and Neurobiology

Early Stage Drug Treatment That Normalizes Proinflammatory Cytokine Production Attenuates Synaptic Dysfunction In A Mouse Model That Exhibits Age-Dependent Progression Of Alzheimer's Disease-Related Pathology, Adam D. Bachstetter, Christopher M. Norris, Pradoldej Sompol, Donna M. Wilcock, Danielle Goulding, Janna H. Neltner, Daret St. Clair, D. Martin Watterson, Linda J. Van Eldik Jul 2012

Early Stage Drug Treatment That Normalizes Proinflammatory Cytokine Production Attenuates Synaptic Dysfunction In A Mouse Model That Exhibits Age-Dependent Progression Of Alzheimer's Disease-Related Pathology, Adam D. Bachstetter, Christopher M. Norris, Pradoldej Sompol, Donna M. Wilcock, Danielle Goulding, Janna H. Neltner, Daret St. Clair, D. Martin Watterson, Linda J. Van Eldik

Sanders-Brown Center on Aging Faculty Publications

Overproduction of proinflammatory cytokines in the CNS has been implicated as a key contributor to pathophysiology progression in Alzheimer's disease (AD), and extensive studies with animal models have shown that selective suppression of excessive glial proinflammatory cytokines can improve neurologic outcomes. The prior art, therefore, raises the logical postulation that intervention with drugs targeting dysregulated glial proinflammatory cytokine production might be effective disease-modifying therapeutics if used in the appropriate biological time window. To test the hypothesis that early stage intervention with such drugs might be therapeutically beneficial, we examined the impact of intervention with MW01-2-151SRM (MW-151), an experimental therapeutic that …

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Open To The Public: Meeting The Nursing Challenge Of A Diverse America, Bonnie Wasilowsky Rn, Bspa-Hca, Cnrn Mar 2011

Open To The Public: Meeting The Nursing Challenge Of A Diverse America, Bonnie Wasilowsky Rn, Bspa-Hca, Cnrn

Patient Care Services / Nursing

No abstract provided.

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Reflexivity In Financial Markets: A Neuroeconomic Examination Of Uncertainty And Cognition In Financial Markets, Steven Pikelny Jan 2011

Reflexivity In Financial Markets: A Neuroeconomic Examination Of Uncertainty And Cognition In Financial Markets, Steven Pikelny

Senior Projects Spring 2011

Financial markets exist to disperse the risks of an unknown future in an economy. But for this process to work in an optimal fashion, investors – and subsequently markets – must have a way to interpret uncertainty. The investor rationality and market efficiency literature utilizes a methodology inadequate to address this fact, so I supplement it with the perspectives of epistemology, economic sociology, neuroscience, cognitive science, and philosophy of mind. This approach suggests that what is commonly viewed as market “inefficiency” is not necessarily caused by investor irrationality, but rather by the inherent nature of the epistemological problem faced by …

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Neurodynamics Of An Election, Armando F. Rocha, Fabio T. Rocha, Marcelo N. Burattini, Eduardo Massad Dec 2009

Neurodynamics Of An Election, Armando F. Rocha, Fabio T. Rocha, Marcelo N. Burattini, Eduardo Massad

Armando F Rocha

Variables influencing decision-making in real settings, as in the case of voting decisions, are uncontrollable and in many times even unknown to the experimenter. In this case, the experimenter has to study the intention to decide (vote) as close as possible in time to the moment of the real decision (election day). Here, we investigated the brain activity associated with the voting intention declared 1 week before the election day of the Brazilian Firearms Control Referendum about prohibiting the commerce of firearms. Two alliances arose in the Congress to run the campaigns for YES (for the prohibition of firearm commerce) …

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Psycho-Social Effects Of A Brain-Training Program Among Healthy Older Adults, Desma Hurley, M. Jean Turner, William C. Bailey Jan 2008

Psycho-Social Effects Of A Brain-Training Program Among Healthy Older Adults, Desma Hurley, M. Jean Turner, William C. Bailey

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

Grounded in cognitive neuroscience and social exchange theory, this research evaluated the relationship between changes in cognitive functioning and two psycho-social dimensions of life among healthy adults over the age of 70 (N=12). Specific psycho-social dimensions examined were social interaction and depression. Six females and six males participated in the study. All were white, college-educated individuals residing in a life-care residential retirement community. The participants used the Posit Science® Brain Fitness Program™, an auditory-based computer training program that improves memory and speed of processing, for forty hours over an eight-week period. Pre- and post-tests related to social interaction and depressive …

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Social Software, Groups, And Governance, Michael J. Madison Jan 2006

Social Software, Groups, And Governance, Michael J. Madison

Articles

Formal groups play an important role in the law. Informal groups largely lie outside it. Should the law be more attentive to informal groups? The paper argues that this and related questions are appearing more frequently as a number of computer technologies, which I collect under the heading social software, increase the salience of groups. In turn, that salience raises important questions about both the significance and the benefits of informal groups. The paper suggests that there may be important social benefits associated with informal groups, and that the law should move towards a framework for encouraging and recognizing them. …

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Law And The Biology Of Rape: Reflections On Transitions, Owen D. Jones Jan 2000

Law And The Biology Of Rape: Reflections On Transitions, Owen D. Jones

Vanderbilt Law School Faculty Publications

This Article serves is a sequel to a previous Article: Sex, Culture, and the Biology of Rape: Toward Explanation and Prevention, 87 Cal. L. Rev. 827 (1999). Part I briefly considers the threshold question: why consider the behavioral biology of sexual aggression at all? Part II proposes that the first step in transitioning to a more accurate and more useful model of rape behavior is to avoid a number of common definitional ambiguities that plague most rape discussions. Because those ambiguities are particularly likely to foster misunderstandings about biobehavioral perspectives, Part II also clarifies the scope of what biobehavioral theories …

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