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Organismal Biological Physiology Commons™
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Full-Text Articles in Organismal Biological Physiology
Rna Virus-Mediated Changes In Organismal Oxygen Consumption Rate In Young And Old Drosophila Melanogaster Males, Eli Hagedorn, Dean Bunnell, Beate Henschel, Daniel Smith Jr, Stephanie Dickinson, Andrew Brown, Maria De Luca, Ashley Turner, Stanislava Chtarbanova
Rna Virus-Mediated Changes In Organismal Oxygen Consumption Rate In Young And Old Drosophila Melanogaster Males, Eli Hagedorn, Dean Bunnell, Beate Henschel, Daniel Smith Jr, Stephanie Dickinson, Andrew Brown, Maria De Luca, Ashley Turner, Stanislava Chtarbanova
Research, Publications & Creative Work
Aging is accompanied by increased susceptibility to infections including with viral pathogens resulting in higher morbidity and mortality among the elderly. Significant changes in host metabolism can take place following virus infection. Efficient immune responses are energetically costly, and viruses divert host molecular resources to promote their own replication. Virus-induced metabolic reprogramming could impact infection outcomes, however, how this is affected by aging and impacts organismal survival remains poorly understood. RNA virus infection of Drosophila melanogaster with Flock House virus (FHV) is an effective model to study antiviral responses with age, where older flies die faster than younger flies due …
Editorial: New Frontiers In The Application Of Stable Isotopes To Ecological And Ecophysiological Research, Keith A. Hobson, John P. Whiteman, Seth D. Newsome
Editorial: New Frontiers In The Application Of Stable Isotopes To Ecological And Ecophysiological Research, Keith A. Hobson, John P. Whiteman, Seth D. Newsome
Biological Sciences Faculty Publications
No abstract provided.
How Acetylation Regulates Metabolic Enzyme Function During Environmental Shifts, Jared Canonigo
How Acetylation Regulates Metabolic Enzyme Function During Environmental Shifts, Jared Canonigo
Biological Sciences Undergraduate Honors Theses
Organisms such as Saccharomyces cerevisiae can regulate the mechanisms of proteins through post-translational modification. These modifications play a vital role in functional proteomic activity because they can regulate protein activity, localization, and interaction with other cellular molecules. Such modifications include phosphorylation, methylation, and acetylation. The metabolic mechanisms of yeast became of keen interest to our lab because our lab noticed many stress defense proteins were being acetylated during stress heat shock. Notably, Adh1p and Adh2p showed both an increase and a decrease in acetylation at two lysine residues (K315 and K314) overtime during heat shock respectively, though the exact function …