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Cytogenetic Test Of Captan And Triethylenemelamine In Mouse Bone Marrow, Stephen M. Fry
Cytogenetic Test Of Captan And Triethylenemelamine In Mouse Bone Marrow, Stephen M. Fry
Honors Theses
Following a single non-toxic i.p. injection with 0.5 or 1.0 mg triethylenemelamine/kig a significant increase in chromosome aberrations in mouse bone marrow was observed 6, 12, 30, but not 54 h after treatment. A single i.p. injection with 250 mg captan/kig caused up to 68% lethality above controls, but no significant increase in chromosome aberrations after the same time intervals. One metacentric chromosome was observed 6, 30, and 54 h after captan treatment among 300, 300, and 101 metaphase spreads respectively, whereas none appeared in 1495 control spreads.