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Full-Text Articles in Bioinformatics
Modeling Hybrid Novel Traits: A Case Study In Complex Petal Pigment Patterning In Hybrid Mimulus, Xingyu Zheng
Modeling Hybrid Novel Traits: A Case Study In Complex Petal Pigment Patterning In Hybrid Mimulus, Xingyu Zheng
Undergraduate Honors Theses
Hybridization between species, by introducing dramatic trait variation into the population and creating viable, transgressive offsprings with novel phenotypes, can have huge evolutionary implications. Some hybrid traits have been studied in the classical genetics or population genetics context, but most complex traits are determined by multiple causes, e.g. the number of loci involved, the rewiring of the genetic circuitries, and the changes in gene expression pattern. Using the hybrid monkeyflower petal pigment patterning as an example, we present a case study to investigate complex hybrid traits in a systematic manner that includes empirical data analysis and quantitative mathematical modeling of …
A Bayesian Network Approach To Feature Selection In Mass Spectrometry Data, Karl W. Kuschner
A Bayesian Network Approach To Feature Selection In Mass Spectrometry Data, Karl W. Kuschner
Dissertations, Theses, and Masters Projects
One of the key goals of current cancer research is the identification of biologic molecules that allow non-invasive detection of existing cancers or cancer precursors. One way to begin this process of biomarker discovery is by using time-of-flight mass spectroscopy to identify proteins or other molecules in tissue or serum that correlate to certain cancers. However, there are many difficulties associated with the output of such experiments. The distribution of protein abundances in a population is unknown, the mass spectroscopy measurements have high variability, and high correlations between variables cause problems with popular methods of data mining. to mitigate these …
A Framework For Implementing Bioinformatics Knowledge-Exploration Systems, John A. Hayes
A Framework For Implementing Bioinformatics Knowledge-Exploration Systems, John A. Hayes
Dissertations, Theses, and Masters Projects
No abstract provided.