Open Access. Powered by Scholars. Published by Universities.®

Bioinformatics Commons

Open Access. Powered by Scholars. Published by Universities.®

William & Mary

Dissertations, Theses, and Masters Projects

Articles 1 - 2 of 2

Full-Text Articles in Bioinformatics

A Bayesian Network Approach To Feature Selection In Mass Spectrometry Data, Karl W. Kuschner Jan 2009

A Bayesian Network Approach To Feature Selection In Mass Spectrometry Data, Karl W. Kuschner

Dissertations, Theses, and Masters Projects

One of the key goals of current cancer research is the identification of biologic molecules that allow non-invasive detection of existing cancers or cancer precursors. One way to begin this process of biomarker discovery is by using time-of-flight mass spectroscopy to identify proteins or other molecules in tissue or serum that correlate to certain cancers. However, there are many difficulties associated with the output of such experiments. The distribution of protein abundances in a population is unknown, the mass spectroscopy measurements have high variability, and high correlations between variables cause problems with popular methods of data mining. to mitigate these …


A Framework For Implementing Bioinformatics Knowledge-Exploration Systems, John A. Hayes Jan 2004

A Framework For Implementing Bioinformatics Knowledge-Exploration Systems, John A. Hayes

Dissertations, Theses, and Masters Projects

No abstract provided.