Open Access. Powered by Scholars. Published by Universities.®
Other Biochemistry, Biophysics, and Structural Biology Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Biomedical Engineering and Bioengineering (2)
- Engineering (2)
- Other Biomedical Engineering and Bioengineering (2)
- Biochemical and Biomolecular Engineering (1)
- Biochemistry (1)
-
- Biological and Chemical Physics (1)
- Biophysics (1)
- Cancer Biology (1)
- Cell Biology (1)
- Cell and Developmental Biology (1)
- Chemical Engineering (1)
- Immunology and Infectious Disease (1)
- Immunology of Infectious Disease (1)
- Microbiology (1)
- Molecular Biology (1)
- Nanoscience and Nanotechnology (1)
- Optics (1)
- Pathogenic Microbiology (1)
- Physical Sciences and Mathematics (1)
- Physics (1)
- Structural Biology (1)
- Keyword
- Publication
- Publication Type
Articles 1 - 3 of 3
Full-Text Articles in Other Biochemistry, Biophysics, and Structural Biology
Antimicrobial Activity And Mechanism Of Amyloid Proteins And Synthetic Conjugated Polyelectrolytes, Fahimeh Maghsoodi
Antimicrobial Activity And Mechanism Of Amyloid Proteins And Synthetic Conjugated Polyelectrolytes, Fahimeh Maghsoodi
Nanoscience and Microsystems ETDs
Although the exact cause of Alzheimer’s disease (AD) is still unknown, it is widely considered that the accumulation of amyloid plaques composed of the amyloid-β (Aβ) peptide in the brain is linked to neurodegeneration. Co-localization of viral DNA with Aβ plaques, the association of brain infection and AD, and research indicating the protective effect of Aβ against bacteria and fungi in mice and human cells have led to the hypothesis that Aβ expression and deposition may be central to its function as an antimicrobial peptide (AMP). In my thesis research, we seek to elucidate how Aβ functions as an AMP …
The Investigation Of Surface Structures On Various Pathogens And Their Interactions With The Human Immune System, Carmen M. Villalobos
The Investigation Of Surface Structures On Various Pathogens And Their Interactions With The Human Immune System, Carmen M. Villalobos
Biomedical Engineering ETDs
The cell surface is the first interface the host immune system encounters and
its investigation has led to a better understanding of cellular biology and types of
pathways that pathogens target in a host cell. The cell surface has evolved to include
many functions such as manipulation of the cytoskeleton, cell signaling, membrane
trafficking, adhesion, and integration into host tissue. The pathogens of interest are
the pathogenic fungus, Candida albicans, and the parasite, Giardia lamblia and we
investigate the consequences of drug treatments on the cell surface, leading to
promising new targets.
Combined High-Speed Single Particle Tracking Of Membrane Proteins And Super-Resolution Of Membrane-Associated Structures, Hanieh Mazloom Farsibaf, Keith A. Lidke
Combined High-Speed Single Particle Tracking Of Membrane Proteins And Super-Resolution Of Membrane-Associated Structures, Hanieh Mazloom Farsibaf, Keith A. Lidke
Shared Knowledge Conference
Many experiments have shown that the diffusive motion of lipids and membrane proteins are slower on the cell surface than those in artificial lipid bilayers or blebs. One hypothesis that may partially explain this mystery is the effect of the cytoskeleton structures on the protein dynamics. A model proposed by Kusumi [1] is the Fence-Picket Model which describes the cell membrane as a set of compartment regions, each ~ 10 to 200 nm in size, created by direct or indirect interaction of lipids and proteins with actin filaments just below the membrane. To test this hypothesis, we have assembled a …