Aquaculture and Fisheries Commons^™

Effects Of Titanium Dioxide Nanoparticle Injections On Tissue Function And Morphology In Goldfish (Carassius Auratus), Bryan Joel Patterson

Graduate Theses

Fish gills are sensitive to a variety of environmental factors because they regulate the exchange of oxygen and ions between the fish and the external environment. This study examined the effects of polyacrylic acid (PAA) coated titanium dioxide nanoparticle injections (TiO₂ NPs) on goldfish (Carassius auratus) over 14 days. Following the experimental period, we examined gill histological samples and looked for signs of an inflammatory response through blood glucose levels and relevant gene expression. TiO₂ injected fish developed a more robust ILCM (interlamellar cell mass) compared to the non-injected controls, which remained elevated over 14 days post injection. …