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2012

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Full-Text Articles in Life Sciences

Excessive Dietary Calcium In The Disruption Of Structural And Functional Status Of Adult Male Reproductive System In Rat With Possible Mechanism, A K. Chandra, Pallav Sengupta, Haimanti Goswami, Mahitosh Sarkar Dec 2011

Excessive Dietary Calcium In The Disruption Of Structural And Functional Status Of Adult Male Reproductive System In Rat With Possible Mechanism, A K. Chandra, Pallav Sengupta, Haimanti Goswami, Mahitosh Sarkar

Pallav Sengupta, PhD

Calcium is essential for functioning of different systems including male reproduction. However, it has also been reported as chemo-castrative agent. The study has been undertaken to elucidate the effect of excessive dietary calcium on male reproductive system in animals with possible action. Adult male healthy rats fed CaCl2 at different doses (0.5 g %, 1.0 g % and 1.5 g %) in diet for 13 and 26 days to investigate reproductive parameters as well as the markers of oxidative stress. Significant alteration was found (p<0.05) in testicular and accessory sex organs weight, epididymal sperm count, testicular steroidogenic enzyme (Δ5 3β-HSD …