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Full-Text Articles in Life Sciences

Mineral Status Of Some Permanent Range Plants For Grazing Sheep In Semi-Arid Areas Of The Chaharmahal And Bakhtiari Province In Iran. 1. Some Macro Minerals, G. H. R. Shadnoush Jun 2023

Mineral Status Of Some Permanent Range Plants For Grazing Sheep In Semi-Arid Areas Of The Chaharmahal And Bakhtiari Province In Iran. 1. Some Macro Minerals, G. H. R. Shadnoush

IGC Proceedings (1997-2023)

A deficiency of one or more of the essential minerals in animals can lead not only to a decrease in productivity but also to metabolic diseases in case of severe deficiencies (McDowell, 1985). In general, mineral, especially phosphorous, deficiencies and imbalances are reported from almost all tropical regions of the world (Matijovic & Durackova, 1994). This study was designed to measure the calcium, phosphorous, magnesium, potassium, sodium and chlorine contents of some plant species in the semi-arid rangeland of Chaharmahal & Bakhtiari Province in Iran, because little information is available at present.


The Effect Of Two Magnesium Fertilisers, Kieserite And Mgo, On Herbage Mg Content, M. B. O'Connor, A. H. C. Roberts, R. Haerdter Jun 2023

The Effect Of Two Magnesium Fertilisers, Kieserite And Mgo, On Herbage Mg Content, M. B. O'Connor, A. H. C. Roberts, R. Haerdter

IGC Proceedings (1997-2023)

Supplementing Mg to dairy cows is widely practised in New Zealand. Various methods are used including drenching, pasture dusting, water trough treatment and adding to hay, silage and other feedstuffs (Young et al., 1979). Fertiliser Mg (calcined magnesite, MgO) is widely used to maintain soil Mg status but research has shown that using fertiliser Mg to achieve good soil, pasture and animal Mg status requires large inputs of Mg (120 kg/ha) and maintaining blood serum Mg status in dairy cows tends to be short-lived without further animal supplementation (O'Connor et al., 1987). The objective of these experiments was …


Potassium Content And The Balance Between Potassium And Other Minerals And Crude Protein In Forage Can Have A Big Impact On Dairy Cow Health, Hary Eriksson Jun 2023

Potassium Content And The Balance Between Potassium And Other Minerals And Crude Protein In Forage Can Have A Big Impact On Dairy Cow Health, Hary Eriksson

IGC Proceedings (1997-2023)

Preliminary studies indicated that the mineral balance in forage may affect dairy cow health. A bigger study covering the four most northern counties in northern Sweden was conducted. The objective of this study was to compare data on harvested forage with farm data on milk yield and animal health.


Distribution Of Trace Elements In Plant Parts Of Red Clover (Trifolium Pratense L.), S. Ignjatovic, Z. Lugic, D. Sokolovic, J. Radovic Jun 2023

Distribution Of Trace Elements In Plant Parts Of Red Clover (Trifolium Pratense L.), S. Ignjatovic, Z. Lugic, D. Sokolovic, J. Radovic

IGC Proceedings (1997-2023)

There is little information on the distribution of minerals in plant parts although factors affecting mineral content in forages have been well investigated (Fleming, 1973; Whitehead et al., 1985). The aim of this investigation was to determine the trace mineral content in plant parts of different cultivars of red clover (foreign and domestic) and to assess differences between cultivars. The existence of significant differences between cultivars would indicate the possibility of selecting cultivars to satisfy particular animal requirements for minerals.


Use Of Green Sulla Forage For Feeding. 2. Effects On Lamb Carcass And Meat Quality, A. Bonanno, M. L. Alicata, G. Tornambè, F. Mazza, G. Di Miceli, D. Giambalvo Jun 2023

Use Of Green Sulla Forage For Feeding. 2. Effects On Lamb Carcass And Meat Quality, A. Bonanno, M. L. Alicata, G. Tornambè, F. Mazza, G. Di Miceli, D. Giambalvo

IGC Proceedings (1997-2023)

Diets with 2.5% of condensed tannins (CT) from carob pulp have been showed to reduce lamb carcass weight, yield and fatness, as a consequence of lower digestibility due to strong protein-tannin bonds. Moreover the diets lightened meat colour and negatively affected meat sensory properties (Priolo et al., 2000). There is evidence that some tannin-rich legumes have weaker stability of the protein-tannin complex post-rumen (McSweeney et al., 2001). Since the CT-containing sulla (Hedysarum coronarium L.) demonstrated improved lamb growth performance in comparison with CT-lacking annual ryegrass (Lolium multiflorum Lam. subsp. wersterwoldicum) (Giambalvo et al., 2005), …


Use Of Green Sulla Forage For Feeding. 1. Effects On Lamb Growth And Gastrointestinal Nematode Parasite Infestation, D. Giambalvo, A. Di Grigoli, M. L. Alicata, B. Formoso, A. S. Frenda, P. Trapani Jun 2023

Use Of Green Sulla Forage For Feeding. 1. Effects On Lamb Growth And Gastrointestinal Nematode Parasite Infestation, D. Giambalvo, A. Di Grigoli, M. L. Alicata, B. Formoso, A. S. Frenda, P. Trapani

IGC Proceedings (1997-2023)

Recent studies have shown that some forage legumes containing condensed tannins (CT), such as sulla (Hedysarum coronarium L.), can reduce the gastrointestinal nematode burden in sheep (Niezen et al., 1998) and increase post-ruminal protein availability (Waghorn et al., 1994). This study aimed to evaluate the anthelmintic and nutritional properties of sulla forage in relation to its CT content. Thus, the growth performance and the level of nematode infestation of lambs fed sulla were compared with those of lambs fed ryegrass (Lolium multiflorum Lam. subsp. wersterwoldicum), lacking in CT.


Leaf, Pod And Whole Plant Tannin Contents In Pigeon Pea (Cajanus Cajan (L.) Millsp), Rodolfo Godoy, P. M. Santos, Francisco H. D. Souza Jun 2023

Leaf, Pod And Whole Plant Tannin Contents In Pigeon Pea (Cajanus Cajan (L.) Millsp), Rodolfo Godoy, P. M. Santos, Francisco H. D. Souza

IGC Proceedings (1997-2023)

Tannin content is an important characteristic of leguminous crops and it has been used as a selection criterion in pigeon-pea improvement programmes (Godoy et al., 1994). In south-eastern Brazil, pigeon pea is often consumed by bovines in the dry season (from April though October), after flowering occurs, and is recommended in some cases, specifically for that time of the year (Lourenço et al., 1994). Since tannin content is being used as a selection criterion and the animals in the dry season preferentially eat pods and leaves, an experiment was conducted to compare whole plant, leaf and pod tannin …


Iconoclasts And Counter Terrorism Against State Organized Terror: A Study Of Perspectives In Nigerian History And Drama, Adebisi Ademakinwa, Saheed Bello Jun 2023

Iconoclasts And Counter Terrorism Against State Organized Terror: A Study Of Perspectives In Nigerian History And Drama, Adebisi Ademakinwa, Saheed Bello

International Review of Humanities Studies

The paper assesses the issue of terrorism as a social reality present in the Nigerian state from its origination and the questions treated by the paper among others include: what dimensions did the occurrences of terrorism take on Nigerian socio-political sphere? What are the counter measures taken by individual and groups in dealing with state organized terrorism? What are the dimensions state organized terrorism take in the modern Nigerian state? Lekan Balogun‟s Ogun Skugga is used primarily while other literary works are used to supplement. The paper argues that the state organized terrorism was a surreptitious method of coercion adopted …


Bio 013: Writing In The Sciences - Human Origins, Esther Muehlbauer Jun 2023

Bio 013: Writing In The Sciences - Human Origins, Esther Muehlbauer

Open Educational Resources

Bio. 013: Writing in the Sciences - Human Origins is an OER syllabus for a College Writing 2 course that develops student writing for different audiences, following the trajectory of how scientists work: Scientists Writing for themselves (a field journal); Scientists writing for other scientists (a review article); Scientists writing for society (an essay for Natural History Magazine).


Cry1 Expression During Postnatal Development Is Critical For The Establishment Of Normal Circadian Period, Aaron Schirmer, Vivek Kumar, Andrew Schook, Eun Joo Song, Michael S. Marshall, Joseph S. Takahashi Jun 2023

Cry1 Expression During Postnatal Development Is Critical For The Establishment Of Normal Circadian Period, Aaron Schirmer, Vivek Kumar, Andrew Schook, Eun Joo Song, Michael S. Marshall, Joseph S. Takahashi

Biology Faculty Publications

The mammalian circadian system generates an approximate 24-h rhythm through a complex autoregulatory feedback loop. Four genes, Period1 (Per1), Period2 (Per2), Cryptochrome1 (Cry1), and Cryptochrome2 (Cry2), regulate the negative feedback within this loop. Although these proteins have distinct roles within the core circadian mechanism, their individual functions are poorly understood. Here, we used a tetracycline trans-activator system (tTA) to examine the role of transcriptional oscillations in Cry1 and Cry2 in the persistence of circadian activity rhythms. We demonstrate that rhythmic Cry1 expression is an important regulator of circadian period. We then define a critical period from birth to postnatal day …


Rural Development Hubs, A Possibility For Nebraska?, Marilyn R. Schlake Jun 2023

Rural Development Hubs, A Possibility For Nebraska?, Marilyn R. Schlake

Cornhusker Economics

The Aspen Institute, Community Strategies Group conducted an analysis of 43 Rural Development Hubs from across the country to discover their strategies, organizational structures, regional roles, and practices. Their aim was to learn how rural regions can help investors, policymakers and other local and regional decision-makers better serve their regions. The following provides an overview of their findings detailed in the report: Rural Development Hubs: Strengthening America’s Rural Innovation Infrastructure. The report provides an opportunity for further discussion on the potential role of Rural Development Hubs in Nebraska. Rural Development Hubs are defined as a “place-rooted organization working hand-in -glove …


Managing Market Volatility In 2023, Jay Parsons, John Hewlett, Jeff Tranel Jun 2023

Managing Market Volatility In 2023, Jay Parsons, John Hewlett, Jeff Tranel

Center for Agricultural Profitability

Current prices for agricultural commodities are strong. The average auction market price in early May for 500–600-pound steer calves in Nebraska was $264 per cwt. Heifer prices were $30 lower, at $234 per cwt. Elevator prices for corn in western Nebraska are in the high $6-per-bushel range. Wheat prices at the elevator are around $8 per bushel. Hay prices are $200 to $300 per ton if you can find it. Severe drought and world market volatilities over the last couple of years have pushed all of these markets higher. Growers and sellers of these commodities are anxious for harvest to …


Radiofrequency Ablation As A Treatment Modality For Primary Hyperparathyroidism: A Systematic Literature Review, Peter P. Issa, Emad Kandil, Grace S. Lee Jun 2023

Radiofrequency Ablation As A Treatment Modality For Primary Hyperparathyroidism: A Systematic Literature Review, Peter P. Issa, Emad Kandil, Grace S. Lee

School of Medicine Faculty Publications

Background: Primary hyperparathyroidism (pHPT) is an endocrine disorder typically characterized by elevated serum calcium and elevated parathyroid hormone (PTH). While parathyroidectomy is the standard treatment, non-operative intervention such as radiofrequency ablation (RFA) has been adopted as an alternative for the management of pHPT, as it has been utilized in other endocrine glands such as thyroid and adrenal. In this literature review, we aim to evaluate the current practice of RFA for pHPT. Methods: A systematic literature search using PubMed, Web of Science, and Embase through June 2022 was conducted. Studies included in the review consisted of patient cohorts who had …


Literature Review—Transthoracic Echocardiography, Computed Tomography Angiography, And Their Value In Clinical Decision Making And Outcome Predictions In Patients With Covid-19 Associated Cardiovascular Complications, Jędrzej Warpechowski, Adam Olichwier, Aleksandra Golonko, Marcin Warpechowski, Robert Milewski Jun 2023

Literature Review—Transthoracic Echocardiography, Computed Tomography Angiography, And Their Value In Clinical Decision Making And Outcome Predictions In Patients With Covid-19 Associated Cardiovascular Complications, Jędrzej Warpechowski, Adam Olichwier, Aleksandra Golonko, Marcin Warpechowski, Robert Milewski

Department of Nutrition and Health Sciences: Faculty Publications

The sudden outbreak of the COVID-19 pandemic posed a great threat to the world’s healthcare systems. It resulted in the development of new methods and algorithms for the diagnosis and treatment of both COVID-19 and its complications. Diagnostic imaging played a crucial role in both cases. Among the most widely used examinations are transthoracic echocardiography (TTE) and computed tomography angiography (CTA). Cardiovascular complications in COVID-19 are frequently associated with a severe inflammatory response, which results in acute respiratory failure, further leading to severe complications of the cardiovascular system. Our review aims to discuss the value of TTE and CTA in …


Evaluating Assessment Score Validity And Characterizing Undergraduate Biology Exam Content, Crystal Uminski Jun 2023

Evaluating Assessment Score Validity And Characterizing Undergraduate Biology Exam Content, Crystal Uminski

School of Biological Sciences: Dissertations, Theses, and Student Research

The landscape of undergraduate biology education has been shaped by decades of reform efforts calling for instruction to integrate core concepts and scientific skills as a means of helping students become proficient in the discipline. Assessments can be used to make inferences about how these reform efforts have translated into changes in department curriculum and course practices. Such changes can be measured using student scores on researcher-developed programmatic and concept assessments. Scores on these assessments are often assumed to be accurate representations of student biology content knowledge, but my work indicates that the validity of these interpretations may be threatened …


A Remote Sensing Approach To Assess The Historical Invasion Of Phragmites Australis In A Brackish Coastal Marsh, Jason S. Hagani, John Y. Takekawa, Steven C. Chappell, Richelle L. Tanner, Adrienne R. Ernst, Karin M. Kettenring Jun 2023

A Remote Sensing Approach To Assess The Historical Invasion Of Phragmites Australis In A Brackish Coastal Marsh, Jason S. Hagani, John Y. Takekawa, Steven C. Chappell, Richelle L. Tanner, Adrienne R. Ernst, Karin M. Kettenring

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Introduction: Coastal estuarine wetlands provide important habitats for a variety of endemic flora and fauna but are particularly vulnerable to biological invasions. Regular monitoring of changes in these vulnerable wetlands has become increasingly important for effective management, especially considering threats from climate change effects and human disturbance. Historical analyzes of plant invasions may guide targeted management strategies to eradicate harmful species. Estimating the distribution of invasive species has never been more accessible with the improved availability of high-resolution data and innovations in remote sensing, estimating the distribution of invasive species has never been more accessible.

Methods: We assessed the spread …


Aggression And Mao-A Gene, Sacheta Sudhendra Kulkarni, Shilpa Sam S, Kishor Manohar Rao, Abhijith Devaraju Jun 2023

Aggression And Mao-A Gene, Sacheta Sudhendra Kulkarni, Shilpa Sam S, Kishor Manohar Rao, Abhijith Devaraju

International Journal of Health and Allied Sciences

No abstract provided.


Sigma-Metric Analysis To Evaluate Quality Management Of Analytical Processes Using Rca And Qgi In A Clinical Biochemistry Laboratory, South India, Sathish Raju Nilakantam, Kusuma Kasapura Shivashankar, Akila Prashant, Melanahalli Dayananda, Suma Maduvanahalli Nataraj, Namratha G Dayananda Jun 2023

Sigma-Metric Analysis To Evaluate Quality Management Of Analytical Processes Using Rca And Qgi In A Clinical Biochemistry Laboratory, South India, Sathish Raju Nilakantam, Kusuma Kasapura Shivashankar, Akila Prashant, Melanahalli Dayananda, Suma Maduvanahalli Nataraj, Namratha G Dayananda

International Journal of Health and Allied Sciences

Introduction: This study aimed to identify laboratory errors at the earliest through Sigma-metric analysis and to evaluate quality management of analytical processes. Methods: Sigma-metrics and Quality Goal Indices (QGI) were calculated by harvesting the IQC and EQC data of an accredited laboratory for 31 biochemical parameters run on Roche Cobas6000 and e411. Those with Sigma 2 were further analysed by applying the various Westgard rules, as suggested. Results: Nearly 13 chemistry analytes showed world-class performance with Sigma > 6 and most of the immunoassay parameters showed marginal performance with sigma > 2 6. Sodium, Chloride, Total T4, Beta-HCG and TSH were found …


Effect Of Fenugreek And Curry Leaves Powder On Dyslipidemia- A Randomized Controlled Pilot Study, Syeda Farha S, Shivani Agarwal, Vanitha Reddy P Jun 2023

Effect Of Fenugreek And Curry Leaves Powder On Dyslipidemia- A Randomized Controlled Pilot Study, Syeda Farha S, Shivani Agarwal, Vanitha Reddy P

International Journal of Health and Allied Sciences

Background: Dyslipidemias, a disorder of lipid metabolism, is widely established as an independent major and modifiable risk factor of cardiovascular disease (CVD). The conditions are common worldwide and a leading cause of death in India, and has even riven the age bar swaying in young people too. The significant effect of an increase in dyslipidemias depends on diabetes and hypertension. Nutraceuticals, derived from food sources serve as an alternative therapy for the management of dyslipidemia. India is home to multitudinous medicinal plants, of which many remain underutilized. Murraya Koenigii (curry leaf) and Trigonella foenum-graecum (fenugreek leaves) are well-proven as good …


Analysis Of Macrophage Migration Inhibitory Factor Genotype In Hemophilia A Patients, Murtadha Ali Hadi, Wijdan Nazar Ibrahim, Meaad Kadhum Hassan Jun 2023

Analysis Of Macrophage Migration Inhibitory Factor Genotype In Hemophilia A Patients, Murtadha Ali Hadi, Wijdan Nazar Ibrahim, Meaad Kadhum Hassan

Hematology/Oncology and Stem Cell Therapy

Background Hemophilia A, an X-linked bleeding disorder, is caused by a complete or partial deficiency in Factor VIII. Multiple factors play a role in the development and progression of bleeding episodes, especially arthropathy, in hemophilia patients. Objectives Detection of macrophage migration inhibitory factor (MIF)-173 G/C polymorphism in people with hemophilia A (PWH) and the possible associations between the type of MIF gene polymorphism and selected disease-related variables. Subjects and Methods This case–control study included 95 male patients aged 2 months to 63 years with hemophilia A and 95 nonhemophiliac subjects matched for age and sex. Allele-specific polymerase chain reaction (AS-PCR) …


Hydrocarbons In Seawater And Fish, With A Special Focus On 16 Epa-Pahs In Marsa Matruh Sediments, Egyptian Mediterranean Sea, Tarek O. Said, Mohamed A. Okbah, Gehan M. El Zokm Jun 2023

Hydrocarbons In Seawater And Fish, With A Special Focus On 16 Epa-Pahs In Marsa Matruh Sediments, Egyptian Mediterranean Sea, Tarek O. Said, Mohamed A. Okbah, Gehan M. El Zokm

Blue Economy

More emphasis is being paid to monitoring hydrocarbon levels and assessing their risk in various marine environmental matrices since they may pose a threat to biodiversity. This research highlighted hydrocarbons in the Marsa Matrouh coastal area of Egypt as the first comprehensive effort to provide a technical basis to assess and address pollution. Surficial sediments and seawater samples (in duplicate) were collected from 10 sites, Triplicate samples of nine fish species were collected from five stations (1, 3, 5, 7, 9) for THC determination. In addition, polycyclic aromatic hydrocarbons (PAHs) residues (16E PA-PAHs) were evaluated in the sediment. THC recorded …


Asymmetric Event-Related Potential Priming Effects Between English Letters And American Sign Language Fingerspelling Fonts, Zed Sevcikova Sehyr, Katherine J. Midgley, Karen Emmory, Phillip J. Holcomb Jun 2023

Asymmetric Event-Related Potential Priming Effects Between English Letters And American Sign Language Fingerspelling Fonts, Zed Sevcikova Sehyr, Katherine J. Midgley, Karen Emmory, Phillip J. Holcomb

Communication Sciences and Disorders Faculty Articles and Research

Letter recognition plays an important role in reading and follows different phases of processing, from early visual feature detection to the access of abstract letter representations. Deaf ASL–English bilinguals experience orthography in two forms: English letters and fingerspelling. However, the neurobiological nature of fingerspelling representations, and the relationship between the two orthographies, remains unexplored. We examined the temporal dynamics of single English letter and ASL fingerspelling font processing in an unmasked priming paradigm with centrally presented targets for 200 ms preceded by 100 ms primes. Event-related brain potentials were recorded while participants performed a probe detection task. Experiment 1 examined …


Smokejumper Obituary: Mccormick, Michael H. (North Cascades 1956), National Smokejumper Association Jun 2023

Smokejumper Obituary: Mccormick, Michael H. (North Cascades 1956), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.


Measuring The Physiological Effects Of Methylobacterium Oryzae Foliar Inoculation Onto Salt-Stressed Tomatoes Grown In A Greenhouse Semi-Hydroponic System, Collin Dice Jun 2023

Measuring The Physiological Effects Of Methylobacterium Oryzae Foliar Inoculation Onto Salt-Stressed Tomatoes Grown In A Greenhouse Semi-Hydroponic System, Collin Dice

Master of Science in Integrative Biology Theses

Salinity stress has been shown to improve hydroponic produce quality such as that of tomato but at the trade-off of produce yield. In order to improve demand for hydroponic produce, techniques that improve salinity tolerance could offset declines in yield without altering the improved quality of produce. In two separate trials, we tested whether foliar inoculation of the ACC deaminase-producing bacteria Methylobacterium oryzae CBMB20 improved salt tolerance in tomatoes grown in a semi-hydroponic system using an indeterminate variety exposed to 26mM NaCl (Trial 1) and a determinate variety exposed to 17mM NaCl (Trial 2). We also tested how salinity and …


Evaluating Nutrient Loading From Agricultural Sources And The Biogeochemical Cycling Capacity Of Environments Connected To Agricultural Lands In Southwestern Ontario, Savannah Knorr Jun 2023

Evaluating Nutrient Loading From Agricultural Sources And The Biogeochemical Cycling Capacity Of Environments Connected To Agricultural Lands In Southwestern Ontario, Savannah Knorr

Electronic Theses and Dissertations

Southwestern Ontario is dominated by agricultural lands that are extensively tile drained throughout the region as a management practice to remove excess water from fields. While tile drainage is a common practice, the implementation of constructed preferential flow paths, along with surface runoff from agricultural lands, increases nutrient loading risks to connected and downstream environments, and receiving large lakes. Of particular concern in this region is Lake Erie which has a legacy of severely degraded water quality due to excess nutrient loading from agricultural lands within the lake’s drainage basin. While agricultural lands are a known source for nutrient loading, …


Assessment Of The First Presentations Of Common Variable Immunodeficiency In A Large Cohort Of Patients, Hossein Esmaeilzadeh, Armita Jokar-Derisi, Amir Hossein Hassani, Reza Yazdani, Samaneh Delavari, Hassan Abolhassani, Negar Mortazavi, Aida Askarisarvestani Jun 2023

Assessment Of The First Presentations Of Common Variable Immunodeficiency In A Large Cohort Of Patients, Hossein Esmaeilzadeh, Armita Jokar-Derisi, Amir Hossein Hassani, Reza Yazdani, Samaneh Delavari, Hassan Abolhassani, Negar Mortazavi, Aida Askarisarvestani

Department of Neurology Faculty Papers

BACKGROUND: Common Variable Immunodeficiency (CVID) is a primary immunodeficiency syndrome resulting in recurrent infections, autoimmunity, and granulomatous manifestations.

METHODS AND MATERIALS: This retrospective study was conducted on an Iranian national registry of immunodeficient patients from 2010 to 2021. The frequency of first presentations of CVID and its association with sex, age of onset, and family history of CVID was evaluated.

RESULTS: A total of 383 patients entered the study, 164 of whom were female, and the rest were male. The mean age of the patients was 25.3 ± 14.5 years. The most frequent first presentations of CVID were pneumonia (36.8%) …


Using Neural Signals To Investigate Athlete Burnout, Mathew R. Hammerstrom, Thomas D. Ferguson, Hendrik L. Pepler, Anthony Pluta, Gordon Binsted, Olave Krigolson Jun 2023

Using Neural Signals To Investigate Athlete Burnout, Mathew R. Hammerstrom, Thomas D. Ferguson, Hendrik L. Pepler, Anthony Pluta, Gordon Binsted, Olave Krigolson

Journal for Sports Neuroscience

Objective: In the present study, we examined the relationships between athlete burnout, brain function, and self-assessment of performance, and how these relationships can be quantified using mobile electroencephalography (mEEG). Specifically, we performed this study to determine whether mEEG can be utilized as an objective measure of athlete burnout. In addition, we sought to determine whether there was any relationship between athlete burnout and athlete self-assessment of performance while controlling for our neural results.

Methods: We tested these relationships in a sample of high-performance athletes – whereby we had athletes complete an mEEG assessment and also had the athletes complete a …


Oncotypedx Testing Does Not Benefit Patients With Grade 1, Estrogen And Progesterone Receptor Positive Breast Cancers: A Tailorx Validated Study, Udai S. Sibia, W. Charles Mylander, Tasha Martin, Martin Rosman, Thomas J. Sanders, Young Lee, Lorraine Tafra, Rubie S. Jackson Jun 2023

Oncotypedx Testing Does Not Benefit Patients With Grade 1, Estrogen And Progesterone Receptor Positive Breast Cancers: A Tailorx Validated Study, Udai S. Sibia, W. Charles Mylander, Tasha Martin, Martin Rosman, Thomas J. Sanders, Young Lee, Lorraine Tafra, Rubie S. Jackson

Hematology/Oncology and Stem Cell Therapy

Background & Objectives We previously described a predictive AAMC model that identifies patients (grade 1, hormone positive) who would not benefit from OncotypeDX testing. The purpose of this study was to validate the AAMC model by assessing distant recurrence-free interval (DRFI) and invasive disease-free survival (IDFS) using TAILORx clinical trial data. Materials & Methods We retrospectively analyzed TAILORx trial data and categorized patients based on the AAMC model. AAMC low-risk patients are those with grade 1 and hormone positive tumors. Kaplan-Meier curves examined DRFI and IDFS. Results Of the total 9195 cases, 2246 (24.4%) were identified as AAMC low-risk. Among …


Post Autologous Hematopoietic Cell Transplant Care In The “Home Sweet Home” Setting: A Treatment Paradigm Shift, Mohamed A. Kharfan-Dabaja, Vivek Roy, Hemant Murthy, Deborah Fischer, Razan Mohty, Ashley Greathouse, Alethea Brown, Kathryn Moreno, Emily Godsey, Jennifer M. Higginbotham, Ashley Bartholomew, Alexis Jackson, Ricardo A. Torres-Guzman, Antonio J. Forte, Sikander Ailawadhi, Roxana Dronca, Michael Maniaci Jun 2023

Post Autologous Hematopoietic Cell Transplant Care In The “Home Sweet Home” Setting: A Treatment Paradigm Shift, Mohamed A. Kharfan-Dabaja, Vivek Roy, Hemant Murthy, Deborah Fischer, Razan Mohty, Ashley Greathouse, Alethea Brown, Kathryn Moreno, Emily Godsey, Jennifer M. Higginbotham, Ashley Bartholomew, Alexis Jackson, Ricardo A. Torres-Guzman, Antonio J. Forte, Sikander Ailawadhi, Roxana Dronca, Michael Maniaci

Hematology/Oncology and Stem Cell Therapy

Multiple myeloma (MM) is the second most common hematologic malignancy with 34,470 estimated new cases in 2022. High-dose therapy followed by autologous hematopoietic cell transplantation (auto-HCT) is a standard treatment for MM even in the era of novel therapies. This is usually done in hospital-based setting, whether in the inpatient or outpatient units. Advanced Care at Home (ACH) represents a virtual hybrid hospital-at-home program that combines a virtual provider-staffed command center with vendor-mediated supply chain capable of delivering high-acuity care in the comfort of patient’s own homes. In our program, we leveraged the existing ACH platform to deliver post-HCT care …


Cytogenetically Normal Acute Myeloid Leukaemia At A Single Centre In South Africa, Nicholas Jenkins, Lee-Ann Phillips, Marian Stone, Estelle Verburgh, Jenna Oosthuizen, Karen Shires Jun 2023

Cytogenetically Normal Acute Myeloid Leukaemia At A Single Centre In South Africa, Nicholas Jenkins, Lee-Ann Phillips, Marian Stone, Estelle Verburgh, Jenna Oosthuizen, Karen Shires

Hematology/Oncology and Stem Cell Therapy

Background: The heterogeneous molecular landscape of cytogenetically normal acute myeloid leukaemia (CN-AML) renders it an ongoing therapeutic challenge. The European Leukaemia Net 2017 guidelines attempted to address this by guiding post-remission therapy according to six prognostically informative mutations. However, its applicability in a South African setting remains elusive due to limited local data. Objectives: This retrospective study aimed to describe a South African CN-AML cohort according to clinicopathological, molecular and treatment outcomes and consequently investigate the local applicability of a triple-mutation testing approach for risk stratification in accordance with the ELN 2017 guidelines, using nucleophosmin (NPM1), fms-like tyrosine kinase internal …