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Articles 91 - 95 of 95
Full-Text Articles in Life Sciences
Amount Of Time Spent In Sedentary Behaviors In The United States, 2003–2004, Charles Matthews, Kong Chen, Patty Freedson, Maciej Buchowski, Bettina Beech, Russell Pate, Richard Troiano
Amount Of Time Spent In Sedentary Behaviors In The United States, 2003–2004, Charles Matthews, Kong Chen, Patty Freedson, Maciej Buchowski, Bettina Beech, Russell Pate, Richard Troiano
Patty S. Freedson
Sedentary behaviors are linked to adverse health outcomes, but the total amount of time spent in these behaviors in the United States has not been objectively quantified. The authors evaluated participants from the 2003–2004 National Health and Nutrition Examination Survey aged ≥6 years who wore an activity monitor for up to 7 days. Among 6,329 participants with at least one 10-hour day of monitor wear, the average monitor-wearing time was 13.9 hours/day (standard deviation, 1.9). Overall, participants spent 54.9% of their monitored time, or 7.7 hours/day, in sedentary behaviors. The most sedentary groups in the United States were older adolescents …
Changes In Physical Activity From Walking To School, John Sirard, Sofiya Alhassan, Tirzah Spencer, Thomas Robinson
Changes In Physical Activity From Walking To School, John Sirard, Sofiya Alhassan, Tirzah Spencer, Thomas Robinson
John Sirard
No abstract provided.
Cardiac Myosin Missense Mutations Cause Dilated Cardiomyopathy In Mouse Models And Depress Molecular Motor Function, Joachim Schmitt, Edward Debold, Ferhaan Ahmad, Amy Armstrong, Andrea Frederico, David Conner, Ulrike Mende, Martin Lohse, David Warshaw, Christine Seidman, J. Seidman
Cardiac Myosin Missense Mutations Cause Dilated Cardiomyopathy In Mouse Models And Depress Molecular Motor Function, Joachim Schmitt, Edward Debold, Ferhaan Ahmad, Amy Armstrong, Andrea Frederico, David Conner, Ulrike Mende, Martin Lohse, David Warshaw, Christine Seidman, J. Seidman
Edward P. Debold
Dilated cardiomyopathy (DCM) leads to heart failure, a leading cause of death in industrialized nations. Approximately 30% of DCM cases are genetic in origin, with some resulting from point mutations in cardiac myosin, the molecular motor of the heart. The effects of these mutations on myosin's molecular mechanics have not been determined. We have engineered two murine models characterizing the physiological, cellular, and molecular effects of DCM-causing missense mutations (S532P and F764L) in the α-cardiac myosin heavy chain and compared them with WT mice. Mutant mice developed morphological and functional characteristics of DCM consistent with the human phenotypes. Contractile function …
A Preliminary Test Of A Student-Centered Intervention On Increasing Physical Activity In Underserved Adolescents, Dawn Wilson, Alexandra Evans, Joel Williams, Gary Mixon, John Sirard, Russell Pate
A Preliminary Test Of A Student-Centered Intervention On Increasing Physical Activity In Underserved Adolescents, Dawn Wilson, Alexandra Evans, Joel Williams, Gary Mixon, John Sirard, Russell Pate
John Sirard
Background—Previous studies have shown that choice and self-initiated behavior change are important for increasing intrinsic motivation and physical activity (PA), however, little of this research has focused on underserved adolescents. Purpose—This study examined the effects of a 4-week student-centered intervention on increasing PA in underserved adolescents. Methods—Twenty-eight students in the intervention school were matched (on race, percentage on free or reduced-price lunch program, gender, and age) with 20 students from another school who served as the comparison group (30 girls, 18 boys; ages 10–12 years; 83% African American; 83% on free or reduced-price lunch). The student-centered intervention was consistent with …
Prevalence Of Active Commuting At Urban And Suburban Elementary Schools In Columbia, Sc, John Sirard, Barbara Ainsworth, Kerri Mclver, Russell Pate
Prevalence Of Active Commuting At Urban And Suburban Elementary Schools In Columbia, Sc, John Sirard, Barbara Ainsworth, Kerri Mclver, Russell Pate
John Sirard
We directly observed the prevalence of walking and bicycling (active commuting) to 8 randomly selected urban and suburban elementary schools. When school was used as the unit of analysis, only 5.0% of the students actively commuted to or from school across all observed trips. Active commuting was not affected (P ≥.18) by school urbanization level, school socioeconomic status, time of day, day of week, weather conditions, or temperature. These results indicate a need for school- and community- based interventions.