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Full-Text Articles in Life Sciences
Incorporating Excess Post-Exercise Oxygen Consumption Into Accelerometer Energy Expenditure Estimation Algorithms, Nicholas Remillard
Incorporating Excess Post-Exercise Oxygen Consumption Into Accelerometer Energy Expenditure Estimation Algorithms, Nicholas Remillard
Masters Theses
Accelerometers are objective monitors of physical activity (PA) that can be used to estimate energy expenditure (EE). Most accelerometer EE estimation equations are based on steady-state data and do not consider excess post-exercise oxygen consumption (EPOC) after exercise. PURPOSE: To quantify the error in accelerometer EE estimates due to EPOC after varying durations of high-intensity treadmill running. METHODS: Nine young, healthy, recreationally active males participated in three study visits. Visit 1 included a treadmill VO2 peak test to determine the treadmill speed correlating to 80% VO2 peak for visits 2 and 3. Visit 2 included a seated 20-min …
Controlling Myosin’S Function Via Interactions Between The Substrate And The Active Site, Mike K. Woodward
Controlling Myosin’S Function Via Interactions Between The Substrate And The Active Site, Mike K. Woodward
Doctoral Dissertations
Molecular motors, such as myosin, have evolved to transduce chemical energy from ATP into mechanical work to drive essential cellular processes, from muscle contraction to vesicular transport. Dysfunction in these motors is a root cause of many pathologies necessitating the application of intrinsic control over molecular motor function. We hypothesized that altering the myosin’s energy substrate via minor positional changes to the triphosphate portion of the molecule will allow us to control the protein and affect its in vitro function. We utilized positional isomers of a synthetic non-nucleoside triphosphate, azobenzene triphosphate, and assessed whether myosin’s force- and motion-generating capacity could …
Age-Related Changes In Corticospinal Drive During Locomotor Adaptation, Sumire D. Sato
Age-Related Changes In Corticospinal Drive During Locomotor Adaptation, Sumire D. Sato
Doctoral Dissertations
During activities of daily living, locomotor patterns must be continuously adapted according to changes in our body (e.g., bodily injuries, fatigue) and to the changing environment (e.g., walking surface). Plasticity of spinal networks and supraspinal centers, including the cerebellum and cerebral cortex, have been shown to play important roles in human locomotor adaptation. However, the neural control of locomotion and the ability to adapt locomotor patterns are altered in older adults, which may limit activities of daily living and increase fall-related injuries in the elderly population. My dissertation project is focused on understanding the role of corticospinal drive during split-belt …