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Full-Text Articles in Applied Mechanics
Multiscale Finite Element Modeling Of Active Contraction In Striated Muscle, Charles Kurtis Mann
Multiscale Finite Element Modeling Of Active Contraction In Striated Muscle, Charles Kurtis Mann
Theses and Dissertations--Mechanical Engineering
Greater than one in three American adults have at least one type of cardiovascular disease, a major cause of morbidity. Computational cardiac mechanics has become an important part of the research effort to understand the heart’s response to mechanical stimuli and as an extension, disease progression and potential therapies. To this end, the present work aims to extend these efforts by implementing a cell level contractile model in which active stress generation in muscle tissue is driven by half-sarcomere mechanics. This is accomplished by enhancing the MyoSim model of actin and myosin in order to produce a multiscale model. This …
Experimental, Analytical, And Numerical Evaluation Of The Mechanical Properties Of The Brain Tissue, Aref Samadidooki
Experimental, Analytical, And Numerical Evaluation Of The Mechanical Properties Of The Brain Tissue, Aref Samadidooki
LSU Doctoral Dissertations
A true understanding of the mechanisms behind most of the brain diseases is still out of reach. For several years, the interest of scientists has been focused on the genetic and biological causes, however, recent studies unraveled the importance of the biomechanics of the brain growth, folding, impact resistance, and deformation on its pathological conditions. While, a wide range of different methods have been used for characterization of the mechanical properties of the brain at the tissue level, the obtained results from different studies are extremely scattered and sometimes in contrast to one another. Since the brain tissue is extremely …