Open Access. Powered by Scholars. Published by Universities.®
Bioelectrical and Neuroengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Medicine and Health Sciences (3)
- Anatomy (2)
- Cells (2)
- Bacteria (1)
- Bacterial Infections and Mycoses (1)
-
- Biological Engineering (1)
- Biology and Biomimetic Materials (1)
- Biomaterials (1)
- Biomechanical Engineering (1)
- Biomedical (1)
- Biomedical Devices and Instrumentation (1)
- Cancer Biology (1)
- Cell and Developmental Biology (1)
- Diseases (1)
- Electrical and Computer Engineering (1)
- Electrical and Electronics (1)
- Endocrine System (1)
- Engineering Science and Materials (1)
- Life Sciences (1)
- Manufacturing (1)
- Materials Science and Engineering (1)
- Mechanical Engineering (1)
- Organisms (1)
- Other Biomedical Engineering and Bioengineering (1)
- Other Engineering Science and Materials (1)
- Signal Processing (1)
- Systems and Integrative Engineering (1)
- Keyword
-
- Allergy (1)
- Anaphylaxis (1)
- Apoptosis (1)
- Auto-injector (1)
- Bicuspid valve (1)
-
- Cancer (1)
- Capsule pump (1)
- Cell death (1)
- Cell membrane (1)
- Computational modeling (1)
- Cytotoxic assay (1)
- Drug delivery (1)
- Electrical stimulation (1)
- Electroporation (1)
- High throughput (1)
- Humans (1)
- Internet of Things (1)
- Internet-of-things (1)
- MRSA (1)
- Microfluidics (1)
- Micropump (1)
- Pancreas (1)
- Pancreatic neoplasms - therapy (1)
- Pudendal nerve stimulation (1)
- Reconfigurable (1)
- Remote (1)
- Shape memory alloy (1)
- Skin infection (1)
- Smartwatch (1)
- Staphylococcus aureus (1)
- Publication
- Publication Type
Articles 1 - 4 of 4
Full-Text Articles in Bioelectrical and Neuroengineering
Shape Memory Alloy Capsule Micropump For Drug Delivery Applications, Youssef Mohamed Kotb
Shape Memory Alloy Capsule Micropump For Drug Delivery Applications, Youssef Mohamed Kotb
Theses and Dissertations
Implantable drug delivery devices have many benefits over traditional drug administration techniques and have attracted a lot of attention in recent years. By delivering the medication directly to the tissue, they enable the use of larger localized concentrations, enhancing the efficacy of the treatment. Passive-release drug delivery systems, one of the various ways to provide medication, are great inventions. However, they cannot dispense the medication on demand since they are nonprogrammable. Therefore, active actuators are more advantageous in delivery applications. Smart material actuators, however, have greatly increased in popularity for manufacturing wearable and implantable micropumps due to their high energy …
Interpatient Differences In Neural Recruitment Patterns During Pudendal Nerve Stimulation – A Computational Investigation, Amolak S. Jhand, Luis C. Ruiz, Nystha Baishya, Ehsan Mirzakhalili, Gaurang Shah, Priyanka Gupta, Tim M. Bruns, Scott F. Lempka
Interpatient Differences In Neural Recruitment Patterns During Pudendal Nerve Stimulation – A Computational Investigation, Amolak S. Jhand, Luis C. Ruiz, Nystha Baishya, Ehsan Mirzakhalili, Gaurang Shah, Priyanka Gupta, Tim M. Bruns, Scott F. Lempka
Medical Student Research Symposium
Bladder dysfunction impairs the quality of life for millions of individuals around the world. Common causes of bladder dysfunction include aging, trauma, and neurological disorders. Due to inadequacies in conventional treatments, neuromodulation therapies to address bladder dysfunction, such as sacral nerve stimulation, have emerged. However, patient needs still remain unmet. Pudendal nerve stimulation (PNS) has recently gained clinical interest as a promising treatment for bladder dysfunction. While PNS has been extensively investigated in preclinical settings, there is a gap in our understanding of the mechanisms of action and efficacy of PNS as limited studies of PNS have been performed on …
Synergistic Effects Of Nanosecond Pulsed Plasma And Electric Field On Inactivation Of Pancreatic Cancer Cells In Vitro, Edwin A. Oshin, Zobia Minhas, Ruben M. L. Colunga Biancatelli, John D. Catravas, Richard Heller, Siqi Guo, Chunqi Jiang
Synergistic Effects Of Nanosecond Pulsed Plasma And Electric Field On Inactivation Of Pancreatic Cancer Cells In Vitro, Edwin A. Oshin, Zobia Minhas, Ruben M. L. Colunga Biancatelli, John D. Catravas, Richard Heller, Siqi Guo, Chunqi Jiang
Bioelectrics Publications
Nanosecond pulsed atmospheric pressure plasma jets (ns-APPJs) produce reactive plasma species, including charged particles and reactive oxygen and nitrogen species (RONS), which can induce oxidative stress in biological cells. Nanosecond pulsed electric field (nsPEF) has also been found to cause permeabilization of cell membranes and induce apoptosis or cell death. Combining the treatment of ns-APPJ and nsPEF may enhance the effectiveness of cancer cell inactivation with only moderate doses of both treatments. Employing ns-APPJ powered by 9 kV, 200 ns pulses at 2 kHz and 60-nsPEF of 50 kV/cm at 1 Hz, the synergistic effects on pancreatic cancer cells (Pan02) …
Nanosecond Pulsed Electric Fields Increase Antibiotic Susceptibility In Methicillin-Resistant Staphylococcus Aureus, Alexandra E. Chittams-Miles, Areej Malik, Erin B. Purcell, Claudia Muratori
Nanosecond Pulsed Electric Fields Increase Antibiotic Susceptibility In Methicillin-Resistant Staphylococcus Aureus, Alexandra E. Chittams-Miles, Areej Malik, Erin B. Purcell, Claudia Muratori
Bioelectrics Publications
Staphylococcus aureus is the leading cause of skin and soft-tissue infections (SSTIs). SSTIs caused by bacteria resistant to antimicrobials, such as methicillin-resistant S. aureus (MRSA), are increasing in incidence and have led to higher rates of hospitalization. In this study, we measured MRSA inactivation by nanosecond pulsed electric fields (nsPEF), a promising new cell ablation technology. Our results show that treatment with 120 pulses of 600 ns duration (28 kV/cm, 1 Hz), caused modest inactivation, indicating cellular damage. We anticipated that the perturbation created by nsPEF could increase antibiotic efficacy if nsPEF were applied as a co-treatment. To test this …