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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Detection Of Sk2 Channels On Hippocampal Neurons, Jamie L. Maciaszek
Detection Of Sk2 Channels On Hippocampal Neurons, Jamie L. Maciaszek
Master's Theses
Calcium-activated small conductance potassium channels (SK) are crucial for synaptic plasticity, sleep, and learning and memory (Hammond, Bond et al. 2006; Cueni, Canepari et al. 2008; Lin, Lujan et al. 2008). Despite the recent progress on SK channel physiology, the precise spatial organization of SK channels in neurons has remained unknown. Such knowledge is critical as the subcellular distribution of SK channels is an important determinant of neuronal excitability. Currently, there are no techniques to image ion channel distribution quantitatively at the nanometer scale in living cells. Here, it is demonstrated that integration of natural toxins with single molecule atomic …
An Open-Source Sandbox For Increasing The Accessibility Of Functional Programming To The Bioinformatics And Scientific Communities, Matthew Fenwick, Colbert Sesanker, Jay Vyas, Michael R. Gryk
An Open-Source Sandbox For Increasing The Accessibility Of Functional Programming To The Bioinformatics And Scientific Communities, Matthew Fenwick, Colbert Sesanker, Jay Vyas, Michael R. Gryk
UCHC Articles - Research
Scientists are continually faced with the need to express complex mathematical notions in code. The renaissance of functional languages such as LISP and Haskell is often credited to their ability to implement complex data operations and mathematical constructs in an expressive and natural idiom. The slow adoption of functional computing in the scientific community does not, however, reflect the congeniality of these fields. Unfortunately, the learning curve for adoption of functional programming techniques is steeper than that for more traditional languages in the scientific community, such as Python and Java, and this is partially due to the relative sparseness of …