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Biomedical Engineering and Bioengineering Commons™
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Full-Text Articles in Biomedical Engineering and Bioengineering
Implementation Of Analytical Fatigue Models Into Opensim To Predict The Effects Of Fatigue On Anterior Cruciate Ligament Loading, Michael A. Samann
Implementation Of Analytical Fatigue Models Into Opensim To Predict The Effects Of Fatigue On Anterior Cruciate Ligament Loading, Michael A. Samann
Mechanical & Aerospace Engineering Theses & Dissertations
The anterior cruciate ligament (ACL) provides stability to the knee joint while performing activities such as a side step cut. Neuromuscular fatigue, a reduction in muscle force producing capabilities, alters lower extremity mechanics while performing a side step cut and may increase the risk of ACL injury, particularly in females. Musculoskeletal modeling allows for the measurement of muscle forces, which are difficult to measure in-vivo. Therefore, musculoskeletal modeling, may improve our understanding of the effects of neuromuscular fatigue on muscle force production and loading of the ACL. Therefore, the purpose of this study was to develop a musculoskeletal model which …
Analysis And Modeling Of The Roles Of Actin-Myosin Interactions In Bladder Smooth Muscle Biomechanics, Seyed Omid Komariza
Analysis And Modeling Of The Roles Of Actin-Myosin Interactions In Bladder Smooth Muscle Biomechanics, Seyed Omid Komariza
Theses and Dissertations
Muscle mechanical behavior potentially plays an important role in some of the most common bladder disorders. These include overactive bladder, which can involve involuntary contractions during bladder filling, and impaired contractility or underactive bladder, which may involve weak or incomplete contractions during voiding. Actin-myosin cross-bridges in detrusor smooth muscle (DSM) are responsible for contracting and emptying the bladder. The total tension produced by muscle is the sum of its preload and active tensions. Studies suggest that actin-myosin cross-links are involved in adjustable preload stiffness (APS), which is characterized by a preload tension curve that can be shifted along the length …