Biomedical Engineering and Bioengineering Commons^™

Piezoelectric Probes And Their Capacity To Monitor Time Varying Viscosity, Eman Ahmed

Theses and Dissertations

Real-time, bedside observation of patient clotting is essential in various surgeries in the operating room (OR), but specifically during cardiac surgeries. The objective of this thesis is to design and test a new piezoelectric device that can be used for viscoelasticity measurement with time as a Point of Care (POC) test. Slow turnaround times (TAT) of current methods to monitor blood viscoelastic changes in patients have led to excessive bleeding and the need for blood transfusions in many situations (Despotis et al, 1997). This study shows that the phase shift produced by a resonator sensor can be related to the …

Dc Dielectrophoretic Assisted Anti-Fouling Filtration System, Nathan M. Cohen

Master's Theses

Filtration processes, whether on the microfluidic, clinical treatment systems, or industrial scale (e.g., point-of-care diagnostics, dialysis, and biopharmaceutical manufacturing, respectively), are often inseparable from membrane clogging (fouling). As a consequence, most, if not all, filtration systems require frequent maintenance to maintain functionality and efficiency. The thesis of this project hypothesizes that Dielectrophoresis can be combined with standard filtration to reduce filter fouling, extending membrane life, and enabling continuous operation. This project investigates a method to reduce fouling, add specificity and efficiency, and decrease the cost and challenge of filtration based biofluid separations.

To substantiate this thesis, we designed, fabricated, and …