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Biomedical Engineering and Bioengineering Commons™
Open Access. Powered by Scholars. Published by Universities.®
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- Biocompatibility (1)
- Bone morphogenetic protein 2 (1)
- Bone repair (1)
- Bone resorption (1)
- Bone sialoprotein (1)
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- Calcium oxide (1)
- Cementum (1)
- Dental implants (1)
- Electrophysiology (1)
- Electrostatic powder coating (1)
- Hippocampus (1)
- Hydroxyapatite (1)
- Kainic acid (1)
- Malocclusion (1)
- Osteo-inductivity (1)
- Periodontal ligament (1)
- Poly(ester-urethane) (1)
- Resting-state networks (1)
- RsfMRI (1)
- Temporal lobe epilepsy (1)
- Ultrafine particles (1)
Articles 1 - 3 of 3
Full-Text Articles in Biomedical Engineering and Bioengineering
The Role Of Bone Sialoprotein In Periodontal Tissue Development And Bone Repair, Yohannes Soenjaya
The Role Of Bone Sialoprotein In Periodontal Tissue Development And Bone Repair, Yohannes Soenjaya
Electronic Thesis and Dissertation Repository
Bone development and repair involve complex processes that include interaction between cells and their surrounding matrix. In the body, bone sialoprotein (BSP) expression is up-regulated at the onset of mineralization. BSP is a multifunctional acidic phosphoprotein with collagen-binding, hydroxyapatite nucleating, and integrin recognition (RGD sequence, which is important for cell-attachment and signaling) regions. Mice lacking BSP expression (Bsp-/-), exhibit a bone phenotype with reductions in bone mineral density, bone length, osteoclast activation, and impaired bone healing. This thesis examined the role of BSP in tooth development and also its potential use as a therapeutic reagent for bone …
The Application Of The Ultrafine Technology In Improving The Biocompatibility And Osteo-Inductivity Of Dental Implants, Nicholas Y. Hou
The Application Of The Ultrafine Technology In Improving The Biocompatibility And Osteo-Inductivity Of Dental Implants, Nicholas Y. Hou
Electronic Thesis and Dissertation Repository
Dental implants are very effective medical devices. However, although stable, the conventional titanium implants are not very bioactive which in some instances could reduce their efficacy. This thesis described the research progress of using polymeric ultrafine-particles with bioactive additives to enrich the surface of titanium substrate, thereby increasing the biocompatibility and osteo-inductivity of the biomaterial. During this doctoral project, three different types of polymers were examined, initially the conventional polyester, and later the novel epoxy as well as the epoxy/polyester hybrid polymers. Physical characterizations confirmed that all of the coating powders were ultrafine particles, and homogeneous surfaces were constructed from …
Resting-State Functional Network Disruptions In A Rodent Model Of Mesial Temporal Lobe Epilepsy (Tle), Ravnoor Singh Gill
Resting-State Functional Network Disruptions In A Rodent Model Of Mesial Temporal Lobe Epilepsy (Tle), Ravnoor Singh Gill
Electronic Thesis and Dissertation Repository
Mesial temporal lobe epilepsy (TLE) is the most common form of drug-refractory epilepsy. The clinical application of non-invasively mapped networks using resting-state functional magnetic resonance imaging (rsfMRI) in humans has been rather limited due to heterogeneous (varying etiology, drugs, onset, latent period, etc.) patient groups. We employed a pharmacological (kainic acid) rodent model of TLE to measure the extent of functional network disruptions using rsfMRI, and study selected behaviors and olfactory to hippocampus transmission. Graph theoretical network modelling and analysis revealed significant increase in functional connectivity connectivity to the temporal lobe (hippocampus) in epileptic-rats compared to controls in the limbic …