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Engineering Science and Materials

2022

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Articles 241 - 246 of 246

Full-Text Articles in Engineering

Medical Applications Of Ultrasound: T-Cell Drug Delivery, Osteoporosis Diagnosis, And Biofilm Mitigation, Alina Karki Jan 2022

Medical Applications Of Ultrasound: T-Cell Drug Delivery, Osteoporosis Diagnosis, And Biofilm Mitigation, Alina Karki

Graduate College Dissertations and Theses

The ability of ultrasound to localize acoustic energy deposition and induce a biological effect within a target is examined in three novel biomedical applications: sonoporation, osteoporosis diagnosis, and biofilm mitigation.Ultrasound can excite encapsulated microbubbles, causing an acoustic cavitation effect in the vicinity of cells, temporarily increasing membrane permeability, and allowing cells to uptake foreign molecules. This non-viral transfection technique is called sonoporation. Our experimental study demonstrated that it could be effective for small interfering RNA (siRNA) delivery into an isolated mouse and human T-cells, which is a complex process despite its importance in treating numerous diseases. T-cells are non-proliferating, while …

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Fabrication Of Soft Gripper Via Direct Inkjet Writing Additive Manufacturing, Evan D. Johnson Jan 2022

Fabrication Of Soft Gripper Via Direct Inkjet Writing Additive Manufacturing, Evan D. Johnson

Electronic Theses and Dissertations

Additive manufacturing (AM) has bloomed recently in the manufacturing field due to its many applications. Direct inkjet writing (DIW) is one of the main am technologies used in the production of grippers. DIW is the most popular taking advantage of materials like silicone and hydrogels. The technology of 3D printing with silicone is still in early stages ,nevertheless, the ability to print with soft materials is very alluring. The implementation of complex geometries in the silicone world would yield vast opportunities in the medical and robotics fields. Additive manufacturing allows for this to be thoroughly examined. In this research these …

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Formation Control Of Mobile Robot Swarm In Search Operation, Chanun Asavasirikulkij Jan 2022

Formation Control Of Mobile Robot Swarm In Search Operation, Chanun Asavasirikulkij

Chulalongkorn University Theses and Dissertations (Chula ETD)

The use of swarm mobile robots has emerged as a promising approach to enhance search efficiency in various applications. This thesis focuses on proposing an effective design and fabrication methodology for a swarm mobile robot system based on the Robot Operating System (ROS) framework. Additionally, a novel network architecture is presented to improve communication efficiency among the robots. The primary objective of this research is to investigate the formation control of swarm mobile robots and their superior ability in search operations. Through extensive experiments and quantitative analysis, the performance of the proposed formation control strategy is evaluated in terms of …

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Development Of Stiffness Sensing And Adaptive Grasping With Soft Pneumatic Grippers, Chaiwuth Sithiwichankit Jan 2022

Development Of Stiffness Sensing And Adaptive Grasping With Soft Pneumatic Grippers, Chaiwuth Sithiwichankit

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study presents a framework for stiffness sensing and adaptive grasping using soft pneumatic grippers (SPGs). The motivation was to imitate the capabilities of human hands. The challenge was the compliance of soft pneumatic actuators (SPAs). The study associated the behaviors of grasped objects with those on SPAs, introduced a new concept of SPA modeling, and proposed a method for stiffness sensing through SPG pincer grasping. Compression testing was conducted for validation. A technique for forecasting deformation and force on grasped objects based on their stiffness was established, and a control law was elaborated. The presented technique and control architecture …

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Simulation And Prototyping Of A Knee Assistive Device For Improved Gait Function, Khemwutta Pornpipatsakul Jan 2022

Simulation And Prototyping Of A Knee Assistive Device For Improved Gait Function, Khemwutta Pornpipatsakul

Chulalongkorn University Theses and Dissertations (Chula ETD)

This study aimed to develop a knee-assistive device while walking. The research was separated into two sections: the gait support simulation in MATLAB and the prototype of the device. Data on body part positions and ground reaction force were collected from three adult Thai participants walking at a speed of 1.5 m/s to calculate knee moment. The simulation section provides support moments during walking using machine learning and artificial stiffness control strategy (MLASCS), composed of the kNN model and the instantaneous artificial stiffness per body mass (IASPB) equations. The MLASCS was used to determine the proper amount of support moment …

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Mechanical Property Evaluation Of Additively Manufactured Materials Across A Wide Temperature Range, Sanket Vinayak Hirve Jan 2022

Mechanical Property Evaluation Of Additively Manufactured Materials Across A Wide Temperature Range, Sanket Vinayak Hirve

Electronic Theses and Dissertations

Additive manufacturing (also called 3d printing) has transitioned from a prototyping-only technology to a technology that is able to create usable parts with complex geometries. 3D printed parts are beginning to be used across all areas of engineering, such as biomedical, aerospace, automobile and many more. Typically, the term “3D printing” refers to layer by layer deposition of polymer materials, while the term “additive manufacturing” refers to layer by layer metal deposition. Conventional manufacturing, or substrative manufacturing, has several main problems that additive manufacturing can help overcome, such as high cost for low volume production, inability to create very complex …

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