Open Access. Powered by Scholars. Published by Universities.®
- Institution
-
- University of Nebraska - Lincoln (665)
- Marquette University (640)
- California Polytechnic State University, San Luis Obispo (529)
- Engineering Conferences International (510)
- Selected Works (426)
-
- Universidad de La Salle (425)
- Utah State University (413)
- New Jersey Institute of Technology (398)
- Purdue University (391)
- Western University (379)
- Old Dominion University (359)
- Virginia Commonwealth University (286)
- Wright State University (281)
- University of Arkansas, Fayetteville (275)
- University of Kentucky (260)
- Clemson University (224)
- City University of New York (CUNY) (189)
- Missouri University of Science and Technology (185)
- Cleveland State University (184)
- Washington University in St. Louis (183)
- SelectedWorks (174)
- Michigan Technological University (166)
- University of Tennessee, Knoxville (162)
- Technological University Dublin (148)
- University of South Florida (146)
- Florida International University (137)
- Santa Clara University (130)
- Wayne State University (127)
- Boise State University (112)
- Louisiana Tech University (111)
- Keyword
-
- Biomechanics (186)
- Tissue engineering (131)
- Biomaterials (115)
- Biomedical Sciences (112)
- Microfluidics (97)
-
- Cancer (93)
- Humans (93)
- Applied sciences (92)
- Biomedical Engineering (86)
- Biomedical engineering (85)
- Bone (79)
- Nanoparticles (78)
- Electrospinning (76)
- Department of Biomedical, Industrial & Human Factors Engineering (73)
- Bioengineering (71)
- Machine learning (71)
- Drug delivery (70)
- Daniel Felix Ritchie School of Engineering and Computer Science (69)
- Engineering (66)
- Department of Biomedical Engineering (65)
- Tissue Engineering (65)
- Rehabilitation (64)
- Gait (63)
- Ultrasound (63)
- Imaging (62)
- Hydrogel (55)
- Kinematics (55)
- Biomedical (54)
- EEG (54)
- Finite element analysis (52)
- Publication Year
- Publication
-
- Biomedical Engineering Faculty Research and Publications (525)
- Theses and Dissertations (466)
- Ciencia y Tecnología para la Salud Visual y Ocular (416)
- Theses (337)
- Electronic Thesis and Dissertation Repository (318)
-
- Biological Systems Engineering: Papers and Publications (297)
- Master's Theses (254)
- Cell Culture Engineering XV (246)
- Doctoral Dissertations (239)
- Electronic Theses and Dissertations (238)
- Biomedical Engineering (231)
- Browse all Theses and Dissertations (188)
- Cells and Materials (166)
- McKelvey School of Engineering Theses & Dissertations (158)
- Chemical and Biochemical Engineering Faculty Research & Creative Works (155)
- Bioelectrics Publications (143)
- USF Tampa Graduate Theses and Dissertations (142)
- The Summer Undergraduate Research Fellowship (SURF) Symposium (127)
- Weldon School of Biomedical Engineering Faculty Publications (127)
- ETD Archive (115)
- Graduate Theses and Dissertations (112)
- All Dissertations (107)
- Biomedical Engineering Undergraduate Honors Theses (101)
- Masters Theses (97)
- Honors Theses (94)
- Publications and Research (92)
- Biomedical, Industrial & Human Factors Engineering Faculty Publications (91)
- All Theses (88)
- All Graduate Theses and Dissertations, Spring 1920 to Summer 2023 (87)
- FIU Electronic Theses and Dissertations (86)
- Publication Type
Articles 91 - 120 of 11012
Full-Text Articles in Engineering
Influence Of Foil Stamping Parameters On Image Quality, Khalima Abishevna Babakhanova, Mukhlisa Ergashevna Khasanova, Aziz Azimjonovich Soadatov, Nigora Junaydullaevna Sadriddinova
Influence Of Foil Stamping Parameters On Image Quality, Khalima Abishevna Babakhanova, Mukhlisa Ergashevna Khasanova, Aziz Azimjonovich Soadatov, Nigora Junaydullaevna Sadriddinova
Technical science and innovation
The paper evaluates the influence of technological process parameters, namely die temperature and pressure force, on the quality of foil stamping, which is one of the types of finishing having a wide range of applications due to giving unique decorative and protective elements to printed products. When evaluating the influence of process parameters on the linearity and coverability of the image, it was found that the pressure force has less influence on the result than the temperature. According to the data of the study, it can be concluded that the maximum percentage of completeness of covering is achieved at a …
Cancer Treatment By Targeting Hdac4 Translocation Induced By Microsecond Pulsed Electric Field Exposure: Mechanistic Insights Through Kinases And Phosphatases, Zahra Safaei
Theses and Dissertations
Epigenetic modifications, arising from sub-cellular shifts in histone deacetylase (HDAC) activity and localization, present promising strategies for diverse cancer treatments. HDACs, enzymes responsible for post-translational histone modifications, induce these epigenetic changes by removing acetyl groups from ε-N-acetyl-lysine residues on histones, thereby suppressing gene transcription. Within the HDAC group, class IIa HDACs are notable for their responsiveness to extracellular signals, bridging the gap between external stimuli, plasma membrane, and genome through nuclear-cytoplasmic translocation. This localization offers two significant mechanisms for cancer treatment: nuclear accumulation of HDACs represses oncogenic transcription factors, such as myocyte-specific enhancer factor 2C (MEF2C), triggering various cell death …
Development Of A Xenograft For Annular Repair Using Pulsed Electric Field Exposures For Enhanced Decellularization, Prince Mensah Kwaku Atsu
Development Of A Xenograft For Annular Repair Using Pulsed Electric Field Exposures For Enhanced Decellularization, Prince Mensah Kwaku Atsu
Theses and Dissertations
Severe back injuries and chronic pain necessitate surgical replacement of damaged intervertebral disc (IVD) cartilage in advanced disease stages. Bovine IVD tissue has been exposed to an upper threshold pulsed electric field (PEF) dose, causing cell death without thermal damage to the tissue. Subsequent PEF exposures at lower magnitudes have accelerated the removal of immunogenic biomolecules though electrokinetic extraction using optimized aqueous solutions. This approach yields a natural scaffold, ready for biocompatibility and mechanical strength assessment. The effects of microsecond pulsed electric fields (µsPEF) on primary bovine AF fibroblast-like cells have been characterized in vitro. PEFs of 10 and 100 …
Inclusive Integration Of Refugees And Migrants In Djibouti's National Healthcare System: Current Situation And Prospects For Improvement, Farhan Houssein Ali, Njah Mansour, Kenza Hassouni
Inclusive Integration Of Refugees And Migrants In Djibouti's National Healthcare System: Current Situation And Prospects For Improvement, Farhan Houssein Ali, Njah Mansour, Kenza Hassouni
Health Sciences
Cet examen narratif vise à décrire et synthétiser les données actuelles sur la situation des migrants et des réfugiés à Djibouti, ainsi que les progrès de la stratégie d'intégration inclusive mise en œuvre par le gouvernement djiboutien. Il s'appuie sur diverses sources, notamment la littérature grise et les publications scientifiques. Les résultats indiquent que le nombre de migrants et de réfugiés est en augmentation constante depuis 2019, avec un état de santé vulnérable et des risques sanitaires alarmants. Il est urgent d'accélérer la mise en œuvre de la stratégie tout en l'adaptant aux données actuelles et d'établir un système fiable …
Satisfaction And Absenteeism To Lectures:Cross-Sectionnel Study Of Dental Students, Manal El Hijazi, Soundouss Soulami, Ihsane Benyahya
Satisfaction And Absenteeism To Lectures:Cross-Sectionnel Study Of Dental Students, Manal El Hijazi, Soundouss Soulami, Ihsane Benyahya
Health Sciences
Introduction: Lectures are still the main pedagogical tool in universities. The aim of this study was to evaluate student satisfaction with lectures and to analyze the factors behind student absenteeism.
Methods: A descriptive cross-sectional study was carried out among dental student by a voluntary, anonymous self-administered questionnaire with open and closed question. Statistical analysis was performed by SPSS version 25 and the Chi2 test was used to compare percentages, with a significance level of p
Advancements And Challenges In Additively Manufactured Functionally Graded Materials: A Comprehensive Review, Suhas Alkunte, Ismail Fidan, Vivekanand Naikwadi, Shamil Gudavasov, Mohammad Alshaikh Ali, Mushfig Mahmudov, Seymur Hasanov, Muralimohan Cheepu
Advancements And Challenges In Additively Manufactured Functionally Graded Materials: A Comprehensive Review, Suhas Alkunte, Ismail Fidan, Vivekanand Naikwadi, Shamil Gudavasov, Mohammad Alshaikh Ali, Mushfig Mahmudov, Seymur Hasanov, Muralimohan Cheepu
Engineering Technology Faculty Publications
This paper thoroughly examines the advancements and challenges in the field of additively manufactured Functionally Graded Materials (FGMs). It delves into conceptual approaches for FGM design, various manufacturing techniques, and the materials employed in their fabrication using additive manufacturing (AM) technologies. This paper explores the applications of FGMs in diverse fields, including structural engineering, automotive, biomedical engineering, soft robotics, electronics, 4D printing, and metamaterials. Critical issues and challenges associated with FGMs are meticulously analyzed, addressing concerns related to production and performance. Moreover, this paper forecasts future trends in FGM development, highlighting potential impacts on diverse industries. The concluding section summarizes …
Developing An Immunomodulatory Strategy Using Biophysical Cues To Modulate Macrophage Phenotype For Fracture Healing And Bone Regeneration, Harshini Suresh Kumar
Developing An Immunomodulatory Strategy Using Biophysical Cues To Modulate Macrophage Phenotype For Fracture Healing And Bone Regeneration, Harshini Suresh Kumar
Theses and Dissertations--Biomedical Engineering
Chronic inflammation is a major cause of the pathogenesis of musculoskeletal diseases such as fragility, fracture, and nonunion. Studies have shown that modulating the immune phenotype of macrophages from proinflammatory to pro-healing can heal recalcitrant bone defects. Current therapeutic strategies predominantly apply biochemical cues, which often lack target specificity, and controlling their release kinetics in vivo is challenging spatially and temporally. We have developed a magnetic iron-oxide nanocomplexes (MNC)-based therapy for resolving chronic inflammation in the context of promoting fracture healing. Here, we show that MNC internalized macrophages, when coupled with an external magnetic field, can exert an intracellular magnetic …
Implementing Unmanned Aerial Vehicles To Collect Human Gait Data At Distance And Altitude For Identification And Re-Identification, Donn E. Bartram
Implementing Unmanned Aerial Vehicles To Collect Human Gait Data At Distance And Altitude For Identification And Re-Identification, Donn E. Bartram
Graduate Theses, Dissertations, and Problem Reports
Gait patterns are a class of biometric information pertaining to the way a person moves and poses. Gait information is unique to each person and can be used to identify and reidentify people. Historically, this task has been achieved through the use of multiple ground-based imaging sensors. However, as Unmanned Aerial Vehicles (UAVs) advance, they present the opportunity to evolve the process of persons identification and re-identification. Collecting human gait data using UAVs at distances ranging from 20m to 500m and altitudes ranging from 0m to 120m is a challenging task. The current biometric data collection methods, primarily designed for …
Domain Adaptive Federated Learning For Multi-Institution Molecular Mutation Prediction And Bias Identification, W. Farzana, M. A. Witherow, I. Longoria, M. S. Sadique, A. Temtam, K. M. Iftekharuddin
Domain Adaptive Federated Learning For Multi-Institution Molecular Mutation Prediction And Bias Identification, W. Farzana, M. A. Witherow, I. Longoria, M. S. Sadique, A. Temtam, K. M. Iftekharuddin
Electrical & Computer Engineering Faculty Publications
Deep learning models have shown potential in medical image analysis tasks. However, training a generalized deep learning model requires huge amounts of patient data that is usually gathered from multiple institutions which may raise privacy concerns. Federated learning (FL) provides an alternative to sharing data across institutions. Nonetheless, FL is susceptible to a few challenges including inversion attacks on model weights, heterogenous data distributions, and bias. This study addresses heterogeneity and bias issues for multi-institution patient data by proposing domain adaptive FL modeling using several radiomics (volume, fractal, texture) features for O6-methylguanine-DNA methyltransferase (MGMT) classification across multiple institutions. The proposed …
Simultaneous Evaluation Of Tibiofemoral And Patellofemoral Mechanics In Total Knee Arthroplasty: A Combined Experimental And Computational Approach, Yashar A. Behnam, Ahilan Anantha Krishnan, Hayden Wilson, Chadd W. Clary
Simultaneous Evaluation Of Tibiofemoral And Patellofemoral Mechanics In Total Knee Arthroplasty: A Combined Experimental And Computational Approach, Yashar A. Behnam, Ahilan Anantha Krishnan, Hayden Wilson, Chadd W. Clary
Center for Orthopaedic Biomechanics: Faculty Scholarship
Contemporary total knee arthroplasty (TKA) has not fully restored natural patellofemoral (P-F) mechanics across the patient population. Previous experimental simulations have been limited in their ability to create dynamic, unconstrained, muscle-driven P-F articulation while simultaneously controlling tibiofemoral (T-F) contact mechanics. The purpose of this study was to develop a novel experimental simulation and validate a corresponding finite element model to evaluate T-F and P-F mechanics. A commercially available wear simulator was retrofitted with custom fixturing to evaluate whole-knee TKA mechanics with varying patella heights during a simulated deep knee bend. A corresponding dynamic finite element model was developed to validate …
Biom 4784: Biomedical Design Studio (Syllabus), Amy Curry
Biom 4784: Biomedical Design Studio (Syllabus), Amy Curry
Biomedical Engineering Syllabi
Course Description: Laboratory experience dedicated to the design, development, and fabrication of a final prototype for use in conducting engineering analysis and design loop feedback. Responsibilities will include frequent team meetings, mentor advising, and group brainstorming along with prototype designing, technical drawings, fabrication, engineering analysis, and verification/validation. Deliverables for each team will be a prototype, final design specification report with engineering reports, and a final team presentation.
Quantification Of Antiviral Drug Tenofovir (Tfv) By Surface-Enhanced Raman Spectroscopy (Sers) Using Cumulative Distribution Functions (Cdfs), Marguerite R. Butler, Jana Hrncirova, Meredith Clark, Sucharita Dutta, John B. Cooper
Quantification Of Antiviral Drug Tenofovir (Tfv) By Surface-Enhanced Raman Spectroscopy (Sers) Using Cumulative Distribution Functions (Cdfs), Marguerite R. Butler, Jana Hrncirova, Meredith Clark, Sucharita Dutta, John B. Cooper
Chemistry & Biochemistry Faculty Publications
Surface-enhanced Raman spectroscopy (SERS) is an ultrasensitive spectroscopic technique that generates signal-enhanced fingerprint vibrational spectra of small molecules. However, without rigorous control of SERS substrate active sites, geometry, surface area, or surface functionality, SERS is notoriously irreproducible, complicating the consistent quantitative analysis of small molecules. While evaporatively prepared samples yield significant SERS enhancement resulting in lower detection limits, the distribution of these enhancements along the SERS surface is inherently stochastic. Acquiring spatially resolved SERS spectra of these dried surfaces, we have shown that this enhancement is governed by a power law as a function of analyte concentration. Consequently, by definition, …
Detection Of Tooth Position By Yolov4 And Various Dental Problems Based On Cnn With Bitewing Radiograph, Kuo Chen Li, Yi-Cheng Mao, Mu-Feng Lin, Yi-Qian Li, Chiung-An Chen, Tsung-Yi Chen, Patricia Angela R. Abu
Detection Of Tooth Position By Yolov4 And Various Dental Problems Based On Cnn With Bitewing Radiograph, Kuo Chen Li, Yi-Cheng Mao, Mu-Feng Lin, Yi-Qian Li, Chiung-An Chen, Tsung-Yi Chen, Patricia Angela R. Abu
Department of Information Systems & Computer Science Faculty Publications
Periodontitis is a high prevalence dental disease caused by bacterial infection of the bone that surrounds the tooth. Early detection and precision treatment can prevent more severe symptoms such as tooth loss. Traditionally, periodontal disease is identified and labeled manually by dental professionals. The task requires expertise and extensive experience, and it is highly repetitive and time-consuming. The aim of this study is to explore the application of AI in the field of dental medicine. With the inherent learning capabilities, AI exhibits remarkable proficiency in processing extensive datasets and effectively managing repetitive tasks. This is particularly advantageous in professions demanding …
Non-Invasive Monitoring Device For Early Detection Of Breast Cancer Related Lymphedema, Amy Prendergast
Non-Invasive Monitoring Device For Early Detection Of Breast Cancer Related Lymphedema, Amy Prendergast
Honors Theses and Capstones
Breast Cancer Related Lymphedema (BCRL) is a common co-morbidity in cancer survivors following neoadjuvant therapies such as chemotherapy, radiation, and/or surgery. It is brought about by the disruption in the lymphatic system (think lymph node biopsy) that leads to a buildup of lymphatic fluid in the arm. Current diagnostic strategies for this condition are merely retroactive, and fairly limited in the parameters that are examined to ensure patient well-being long term. We hypothesize that with an approach that mimics bioimpedance spectroscopy analysis, we will be able to provide a clinical support tool that would better determine early stages of lymphedema …
The Effect Of 17Β Estradiol On Local Production Of Active Vitamin D3 Metabolites In Laryngeal Squamous Cell Carcinoma, Tillat Batool
The Effect Of 17Β Estradiol On Local Production Of Active Vitamin D3 Metabolites In Laryngeal Squamous Cell Carcinoma, Tillat Batool
Theses and Dissertations
Laryngeal squamous cell carcinoma (LSCC) has garnered attention as a sex-hormone-dependent cancer with notable responsiveness to 17β-estradiol (E2), in which it’s tumorigenesis can be mediated through estrogen receptors (ER). The ESR1 gene encodes for the classical full-length ERα66, as well as splice variants ERα36 and ERα46. Previous studies have shown that an active vitamin D3metabolite, 24R,25(OH)2D3. has pro-tumorigenic or anti-tumorigenic responses in LSCC cells with different ER profiles, and that the tumor cells have the capability of localized production of vitamin D metabolites at the cellular level when treated with 25(OH)D3-d6 …
Biom 3110: Medical Physiology (Syllabus), Bradford D. Pendley
Biom 3110: Medical Physiology (Syllabus), Bradford D. Pendley
Biomedical Engineering Syllabi
Course Description: Basic principles of human physiology and how these are applied in medicine and biomedical engineering problem and devices; physiological principles using appropriate mathematical and engineering models to construct an understanding of how the body works as an integrated system.
Biom 4802/6802: Assertion-Evidence Model For Presentations In Engineering And Science (Syllabus), Amber Jennings
Biom 4802/6802: Assertion-Evidence Model For Presentations In Engineering And Science (Syllabus), Amber Jennings
Biomedical Engineering Syllabi
Course Description: This course will provide training and practice in delivering scientific presentations to diverse audiences. Students will design and deliver presentations of scientific data for different audience categories.
Biom 7904: Ultrasound Imaging Technology (Syllabus), Carl Herickhoff
Biom 7904: Ultrasound Imaging Technology (Syllabus), Carl Herickhoff
Biomedical Engineering Syllabi
Course Description: This course will introduce students to a variety of current and emerging methods in ultrasound imaging. Concepts will be grounded in fundamental physical principles (acoustic waves, piezoelectric transduction, diffraction, scattering) and progress to methods of array beamforming, k-space representation, and imaging system architecture. Ultrasound nonlinearity, bioeffects, safety metrics, as well as Doppler (flow), harmonic, contrast-enhanced, and elastography imaging methods will also be introduced. Students will have the opportunity to observe ultrasound experiments and perform ultrasound imaging on an abdominal phantom.
Biom 3710: Physiological Systems And Modeling (Syllabus), Stephen Strain
Biom 3710: Physiological Systems And Modeling (Syllabus), Stephen Strain
Biomedical Engineering Syllabi
Course Description: Fundamentals of control theory and mathematical modeling and analysis as applied to physiological systems.
Biom 4410/Mech 4397: Engineering Practicum (Syllabus), Sheila Moses, Jeff Marchetta, Amy Curry
Biom 4410/Mech 4397: Engineering Practicum (Syllabus), Sheila Moses, Jeff Marchetta, Amy Curry
Biomedical Engineering Syllabi
Course Description: Preparation for professional practice through experiential learning under the supervision of an experienced engineer with oversight by a member of the department’s faculty. Regular reporting throughout course required.
Biom 4720/6720: Bioelectricity (Syllabus), Amy Curry
Biom 4720/6720: Bioelectricity (Syllabus), Amy Curry
Biomedical Engineering Syllabi
Course Description: Bioelectricity, including calculations of potential fields resulting from cardiac or neural electrogeneration; treatment of how heart and nerves generate and propagate electrical signals.
Biom 2720: Experimental Design And Analysis For Biomedical Engineering (Syllabus), Stephen Strain
Biom 2720: Experimental Design And Analysis For Biomedical Engineering (Syllabus), Stephen Strain
Biomedical Engineering Syllabi
Description: Application of probability, statistics, error analysis, uncertainty in design and performance of biomedical engineering experimentation; discussion and evaluation of common experimental designs for medical device development.
Biom 4782: Biomedical Design Practicum (Syllabus), Amy Curry
Biom 4782: Biomedical Design Practicum (Syllabus), Amy Curry
Biomedical Engineering Syllabi
Course Description: Practical application of biomedical design principles with emphasis on project management, teamwork, prototype production, risk analysis and management, technical drawings, patent review with claim development, market analysis, regulatory issues, professional and ethical responsibilities of a biomedical engineer, engineering analysis/reports, incorporation of standards, prototype verification/validation, and presentation skills.
Biom 1720: Introduction To Biomedical Engineering Tools, Stephen Strain
Biom 1720: Introduction To Biomedical Engineering Tools, Stephen Strain
Biomedical Engineering Syllabi
Course Description: Use of computer tools for data analysis, presentation, documentation; introduction to programming; individual and group design projects.
Levofloxacin Incorporated Extracellular Matrix Nanoparticles For Pulmonary Cystic Fibrosis Infections, Raahi Patel
Levofloxacin Incorporated Extracellular Matrix Nanoparticles For Pulmonary Cystic Fibrosis Infections, Raahi Patel
Theses and Dissertations
Cystic fibrosis (CF) is a progressive genetic disorder that affects around 40,000 people in the United States. CF is characterized by a mutation in the CFTR protein that causes dysregulated ion transport across epithelial cells, producing viscous mucus in the lung that increases bacterial invasion, causing persistent infections and subsequent inflammation. Pseudomonas aeruginosa and Staphylococcus aureus are two of the most common infections in CF patients that are resistant to antibiotics. One antibiotic approved to treat these infections is levofloxacin (LVX) that functions to inhibit bacterial replication, but can be further developed into tailorable particles. Nanoparticles are an emerging inhaled …
Assessing The Relationship Between Contralateral Limb Synergy And Rock Climbing Efficiency, Jeromy Miramontes
Assessing The Relationship Between Contralateral Limb Synergy And Rock Climbing Efficiency, Jeromy Miramontes
Theses, Dissertations and Capstones
Rock climbing is a total body sport testing the mental and physical capabilities of athletes. Efficiency of movement can improve the ability of climbers to perform at a higher capacity and reduce the risk of injury. Data on the relationship between the continuous relative phase (CRP) of contralateral joint rotations and time to completion of a bouldering move are ways to assess rock climbing. This study aimed to assess this relationship, as well as the geometric entropy (GE) of the center of mass displacement when completing the bouldering move, and the metabolic efficiency over 4 min of bouldering. The study …
Bridging Language Barriers In Clinical Screening: Leveraging Large Language Models (Llms) To Generate Bilingual Screening Surveys For Patients With Limited English Proficiency (Plep), Tyler Vandyk
Family Medicine Clerkship Student Projects
This study addresses the critical need for accessible clinical screening in communities with a high incidence of Patients with Limited English Proficiency (PLEP). Recognizing the limitations of existing interpreter services and the scarcity of validated translations for standard clinical surveys like PHQ-9 and GAD-7, we developed a novel approach leveraging Large Language Models (LLMs). Our method utilizes GPT-4 to create bilingual versions of these surveys, which are then formatted into printable PDFs via a Python script and LuaLaTeX compiler. The resulting surveys, validated for translation accuracy and cultural competency, are made accessible through a Google repository. Preliminary results demonstrate that …
Advancing Biological Applications Through Microfluidic-Based Tool Development, K.M. Taufiqur Rahman
Advancing Biological Applications Through Microfluidic-Based Tool Development, K.M. Taufiqur Rahman
Electronic Theses and Dissertations
This research undertook an interdisciplinary approach, integrating bioengineering, microbiology, molecular biology, and systems biology to investigate bacterial dynamics behavior. Specifically, it delved into the development of microfluidic devices for biological applications such as bacterial cell counts, real-time observation of plant roots (here, specialized lectin-coated microbeads are used that mimic root characteristics), and soil microbe interactions. Furthermore, Next-Generation Sequencing and systems biology methodologies were employed to explore the intricate, multifaceted survival mechanisms of Escherichia coli persister population. Studying and quantifying persisters or testing for the existence of VBNC (viable but nonculturable) is challenging. These experiments require precise counts. It has been …
Plasma Protein Signatures Of Adult Asthma, Gordon J. Smilnak, Yura Lee, Abhijnan Chattopadhyay, Annah B. Wyss, Julie D. White, Sinjini Sikdar, Jianping Jin, Andrew J. Grant, Alison A. Motsinger-Reif, Jian-Liang Li, Mikyeong Lee, Bing Yu, Stephanie J. London
Plasma Protein Signatures Of Adult Asthma, Gordon J. Smilnak, Yura Lee, Abhijnan Chattopadhyay, Annah B. Wyss, Julie D. White, Sinjini Sikdar, Jianping Jin, Andrew J. Grant, Alison A. Motsinger-Reif, Jian-Liang Li, Mikyeong Lee, Bing Yu, Stephanie J. London
Mathematics & Statistics Faculty Publications
Background: Adult asthma is complex and incompletely understood. Plasma proteomics is an evolving technique that can both generate biomarkers and provide insights into disease mechanisms. We aimed to identify plasma proteomic signatures of adult asthma.
Methods: Protein abundance in plasma was measured in individuals from the Agricultural Lung Health Study (ALHS) (761 asthma, 1095 non-case) and the Atherosclerosis Risk in Communities study (470 asthma, 10,669 non-case) using the SOMAScan 5K array. Associations with asthma were estimated using covariate adjusted logistic regression and meta-analyzed using inverse-variance weighting. Additionally, in ALHS, we examined phenotypes based on both asthma and seroatopy (asthma with …
Synergistic Effects Of Nanosecond Pulsed Plasma And Electric Field On Inactivation Of Pancreatic Cancer Cells In Vitro, Edwin A. Oshin, Zobia Minhas, Ruben M. L. Colunga Biancatelli, John D. Catravas, Richard Heller, Siqi Guo, Chunqi Jiang
Synergistic Effects Of Nanosecond Pulsed Plasma And Electric Field On Inactivation Of Pancreatic Cancer Cells In Vitro, Edwin A. Oshin, Zobia Minhas, Ruben M. L. Colunga Biancatelli, John D. Catravas, Richard Heller, Siqi Guo, Chunqi Jiang
Bioelectrics Publications
Nanosecond pulsed atmospheric pressure plasma jets (ns-APPJs) produce reactive plasma species, including charged particles and reactive oxygen and nitrogen species (RONS), which can induce oxidative stress in biological cells. Nanosecond pulsed electric field (nsPEF) has also been found to cause permeabilization of cell membranes and induce apoptosis or cell death. Combining the treatment of ns-APPJ and nsPEF may enhance the effectiveness of cancer cell inactivation with only moderate doses of both treatments. Employing ns-APPJ powered by 9 kV, 200 ns pulses at 2 kHz and 60-nsPEF of 50 kV/cm at 1 Hz, the synergistic effects on pancreatic cancer cells (Pan02) …