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Knowledge-Based Analysis Of Genomic Expression Data By Using Different Machine Learning Algorithms For The Purpose Of Diagnostic, Prognostic Or Therapeutic Application, Venkata Jagan Mohan Thodima

Dissertations

With more and more biological information generated, the most pressing task of bioinformatics has become to analyze and interpret various types of data, including nucleotide and amino acid sequences, protein structures, gene expression profiling and so on. In this dissertation, we apply the data mining techniques of feature generation, feature selection, and feature integration with learning algorithms to tackle the problems of disease phenotype classification, clinical outcome and patient survival prediction from gene expression profiles.

We analyzed the effect of batch noise in microarray data on the performance of classification. Batchmatch, a batch adjusting algorithm based on double scaling method …

Gifted Education Exposure In Introductory Special Education Texts: Quantitative Text Content Analysis, Sandra Kay Hansen Wentworth

Dissertations

This present study was designed to examine and compare 10 introductory special education textbooks used in mandatory introductory special education courses. The percentage of text devoted to gifted education chapters in comparison to specific learning disabilities, behavior disorders, mental retardation, autism spectrum disorders, and speech/language/communication disorders was explored for statistically significant differences. Paired samples t tests were conducted to analyze the data. A statistically significant difference was found between the coverage of gifted education and autism spectrum disorders among the 10 examined texts. No other significant statistical findings were found between various exceptionalities among the 10 examined texts. The prevalence …

Factors That Are Associated With Students' Standardized Reading Achievement Scores, Cherie Nichole Mothershead

Dissertations

This study examined the factors that are associated with students' standardized reading achievement scores. The participants in this study were obtained from two sources: a national and a regional sample. The national participants were located throughout the United States of America, and the regional participants were from a school district in a southeastern state.

The data for the national sample were provided by the National Center for Education Statistics (NCES), a division of the U.S. Department of Education, and the regional sample was provided by surveying all fifth grade teachers in a school district from a southeastern state. These two …

Identification Of Two Distinct Glutaminyl Cyclase Isoforms In Drosophila Melanogaster, Amanda Thigpen Parker

Dissertations

Sequence analyses revealed two putative glutaminyl cyclase genes in Drosophila melanogaster with greater than 60% amino acid sequence identity to previously identified glutaminyl cyclase in humans. Expression, purification, and characterization of both putative proteins revealed two enzymatically active glutaminyl cyclase enzymes. Comparison of the Drosophila melanogaster glutaminyl cyclase enzymes to the published human glutaminyl cyclase revealed the enzymes were very similar. The Km values obtained were identical to those of human glutaminyl cyclase for three different substrates tested. However, the Drosophila glutaminyl cyclases demonstrated lower turnover numbers. Both Drosophila glutaminyl cyclase isoforms were inhibited by imidazole, imidazole derivatives, and metal …

Shadows Over Goshen: Plain Whites, Progressives And Paternalism In The Depression South, Fred Carl Smith

Dissertations

This dissertation is about poverty and rural Southerners and the beginnings of America's rational assault on poverty. By 1932, a sense of emergency and desperation permeated American economic and political thinking. The apparent collapse of the industrial economy and credit markets created an environment in which politicians allowed and the public demanded bold experimentation. The period, 1933-1937, in which most of America approved or tolerated progressive notions, offered an opportunity for progressives to demonstrate their solutions to persistent southern poverty. The Division of Subsistence Homesteads (DSH), an agency of the Department of Interior, created communities that combined subsistence gardening with …

Perceptions And Knowledge Of Special Education Law Among Building Administrators In A Selected Georgia School District, Patricia Claire Grasso

Dissertations

The Individuals with Disabilities Education Act (IDEA) has impacted every school district in the United States and significantly altered the role of administrators. Requirements for the administration and supervision of special education have developed exponentially since the enactment of Public Law 94- 142 and its reauthorization as the IDEA.

The purpose of this study was to compare the perceptions and knowledge of building administrators regarding special education law. The following research questions were developed to facilitate this study: (a) is there a difference in the level of knowledge about special education law among building administrators regarding the seven provisions of …

The Role Of Teachers In School Safety, Leslie Lee Brown

Dissertations

This study examined teachers' perceptions of their abilities to effectively respond to crises on their school campuses. Teachers were surveyed in numerous southeastern states in contrasting demographic areas. Much of the literature addressed acts of violence, natural disasters, and threats of terrorism in schools. Past literature designates urban areas as places where violence has been a more prevalent element of everyday life. Current evidence shows that school shootings and natural disasters can occur anywhere. This shows that planning, practicing, and preparing for crises events are imperative no matter the demographic area in which a school is located. However, there is …

Induction And Peer Coaching Programs In A Middle School Setting, Shanti Ladawn Howard

Dissertations

While almost half of new teachers engage in some type of induction program, many programs only offer superficial types of assistance including district-wide orientations, periodic workshops, or instruction in classroom management (Gold, 1996). Some induction programs sponsored by the state institute an evaluation process that applies formulaic criteria for defining teaching behaviors to assess new teacher performances (Darling-Hammond et al., 1999). In the continued search for school improvement, there was a need to propose another option in staff development, e.g., peer coaching.

Peer coaching was examined because induction programs did not attend to the individual needs of alternatively certified teachers. …

The Emotional Intelligence And Resilience Of School Leaders: An Investigation Into Leadership Behaviors, Aileen Thompson Bumphus

Dissertations

Recent research suggests that leadership in schools and emotional intelligence are related. Furthermore, resiliency has been researched and found to be linked to successful leadership. As a result of these findings and the researcher's own professional experiences, it is speculated that emotional intelligence, resilience, and school leadership may be highly related factors in how one leads a school. The study of this three-factor relationship has been virtually overlooked in the research on school leadership and might prove useful in the recruitment, identification, development, and retention of effective school leaders.

A study of the emotional intelligence, resilience, and leadership of public …

Identifying Preschool Students In Need Of Early Intervention, Cassie Delso Wells

Dissertations

The purpose of this study was to investigate a screening instrument targeting identification of preschool students in need of early intervention in order to determine the screening instrument's predictive validity. This study specifically examined the relationship between student scores on the DIALS and student achievement in reading at the end of first grade. All participants in the study were residing on Alaska's North Slope and the majority were Alaska Natives. The remote geographic location of the North Slope along with the ancient traditions of the Inupiat Eskimos, including the Inupiaq language that is still spoken among the residents of the …

A Metamorphosis Of Thought: Parent Education Based On Transformative Learning Theory In A Title I-Funded Middle School, Ayanna Lichelle Shivers

Dissertations

Section 1118(e)(2) of the No Child Left Behind Act of 2001 encouraged public schools to conduct and evaluate parent education programs to assist with closing the achievement gap. In an effort to combat the existing problem, the researcher engaged in a mixed-methods study to address four research questions.

A comparative-quantitative study, using the Middle School Parent Perception Survey, was conducted to determine if there were statistically significant differences in perceptions of parents whose children attended Title I funded and non-Title l-funded schools in the following areas—barriers to parent involvement, their ability to assist their children with schoolwork, and the support …

Rhetoric With Humor: An Analysis Of Hispanic/Latino Comedians' Uses Of Humor, George Pacheco Jr.

Dissertations

Hispanic/Latino comedians' use of humor as argument is a rich environment to study. The relationship between the comedian (as the joke teller) and the audience (as the receivers of the joke) creates an environment where many topical boundaries fall, and the comedian is free to express him/herself without fear of persecution or ridicule. More specifically, this setting allows the comedian to use the platform as joke teller to communicate arguments to the audience through humor. Comedians who use humor rhetorically often communicate arguments about well-known stereotypes freely because audiences attend shows expecting to laugh.

Using Kenneth Burke's (1959) perspective by …

Middle-Level Leaders Perceptions Of Accountability, Deena Cousar Brown

Dissertations

The purpose of this study was to identify the perceptions of middle-level principals personal and school accountability, their perceptions of beliefs and competencies that influence improvement in student achievement and accomplishment of accountability, and their perceptions regarding the adequacy of professional development and preparation for middle-level principals that affect their ability to improve student achievement and perform their leadership role in an increased accountability environment. This study specifically examined differences in the perceptions of middle-level principals' accountability based on the socioeconomics of the school, the number of years of administrative experience, and previous middle-school teaching experience.

National Folk Festival Visitor Study: 2008, Christine Oschell

Institute for Tourism and Recreation Research Publications

The purpose of this study was to provide the organizers of the National Folk Festival with an understanding of their attendees and the total money spent in Butte during the event.

Richfield Field Office Planning Area - Proposed Resource Management And Final Environmental Impact Statement, United States Department Of The Interior, Bureau Of Land Management

Final environmental Impact Statements (UT)

The Proposed RMP was crafted primarily from the Preferred Alternative presented in the DRMP/DEIS (Alternative B) and includes other decisions within the range of alternatives (Alternatives N, A, C, and D) in response to public comments and internal review. The No Action Alternative (Alternative N) reflects current management. The BLM has removed the DRMP/DEIS Alternative B (Preferred Alternative) from the PRMP/FEIS. The other DRMP/DEIS Alternatives (Alternatives N, A, C, and D) and analyses are carried forward in the PRMP/FEIS only for comparative purposes and to correct some mistakes that were identified during the public comment period.

Moab Field Office Planning Area Proposed Resource Management Plan And Final Environmental Impact Statement, United States Department Of The Interior, Bureau Of Land Management

Final environmental Impact Statements (UT)

This Proposed Resource Management Plan (RMP) and Final Environmental Impact Statement (EIS) describes and analyzes the Proposed Plan and draft alternatives for the planning and management of public lands and resources administered by the Bureau of Land Management (BLM), Moab Field Office. The Moab planning area is located in southeastern Utah and includes approximately 2.5-million acres of land in Grand and San Juan Counties. Within the Moab planning area, the BLM manages approximately 1.8-million acres of BLM-administered public land surface as well as about 29,000 acres of federal mineral estate.

Metrics For Solar Wind Prediction Models: Comparison Of Empirical, Hybrid, And Physics‐Based Schemes With 8 Years Of L1 Observations, M. J. Owens, Harlan E. Spence, S. Mcgregor, W. J. Hughes, J. M. Quinn, C. N. Arge, P. Riley, J. Linker, D. Odstrcil

Physics & Astronomy

[1] Space weather effects on technological systems originate with energy carried from the Sun to the terrestrial environment by the solar wind. In this study, we present results of modeling of solar corona-heliosphere processes to predict solar wind conditions at the L1 Lagrangian point upstream of Earth. In particular we calculate performance metrics for (1) empirical, (2) hybrid empirical/physics-based, and (3) full physics-based coupled corona-heliosphere models over an 8-year period (1995–2002). L1 measurements of the radial solar wind speed are the primary basis for validation of the coronal and heliosphere models studied, though other solar wind parameters are also considered. …

Ambient Solar Wind's Effect On Icme Transit Times, A. W. Case, Harlan E. Spence, M. J. Owens, P. Riley, D. Odstrcil

Physics & Astronomy

[1] Most empirical and numerical models of Interplanetary Coronal Mass Ejection (ICME) propagation use the initial CME velocity as their primary, if not only, observational input. These models generally predict a wide spread of 1 AU transit times for ICMEs with the same initial velocity. We use a 3D coupled MHD model of the corona and heliosphere to determine the ambient solar wind's effect on the propagation of ICMEs from 30 solar radii to 1 AU. We quantitatively characterize this deceleration by the velocity of the upstream ambient solar wind. The effects of varying solar wind parameters on the ICME …

Ten Years Of Community Profiles In New Hampshire, Charlie A. French, Fabienne Lord-Fonesca

Natural Resources & the Environment

Through a program called Community Profiles, the University of New Hampshire Cooperative Extension has helped 57 New Hampshire communities develop a vision for their future and mobilize local residents to act on that vision. The Community Profile process is based on the premise that communities must engage members in identifying and documenting common and deeply held values from which to craft a vision for the future if they are to build and sustain community vitality. The process also helps communities find new and creative ways to pursue that vision by leveraging resources within and outside of the community. These resources …

Evaluating Children’S Advocacy Centers’ Response To Child Sexual Abuse, Theodore P. Cross, Lisa M. Jones, Wendy A. Walsh, Monique Simone, David Kolko, Joyce Sczepanski, Tonya Lippert, Karen Davison, Arthur Crynes, Polly Sosnowski, Amy L. Shadoin, Suzanne Magnuson

Sociology

Children’s Advocacy Centers (CACs) play an increasingly significant role in the response to child sexual abuse and other child maltreatment in the United States. First developed in the 1980s, CACs were designed to reduce the stress on child abuse victims and families created by traditional child abuse investigation and prosecution procedures and to improve the effectiveness of the response. According to several experts (Fontana, 1984; Pence and Wilson, 1992; Whitcomb, 1992), child victims were subjected to multiple, redundant interviews about their abuse by different agencies, and were questioned by professionals who had no knowledge of children’s developmental limitations or experience …

Experience, Reflect, Critique: The End Of The “Learning Cycles” Era, Jayson O. Seaman

Kinesiology

According to prevailing models, experiential learning is by definition a stepwise process beginning with direct experience, followed by reflection, followed by learning. It has been argued, however, that stepwise models inadequately explain the holistic learning processes that are central to learning from experience, and that they lack scientific or philosophical foundations. Criticism also centers on the way complex cultural, social, and physical processes during experience and learning are reduced to a rational, excessively cognitive, individual phenomenon. This article reviews this criticism and adds a historical dimension to the analysis, concluding that existing cyclic models might be better valued for their …

Rhythms Of Locomotion Expressed By Limulus Polyphemus, The American Horseshoe Crab: I. Synchronization By Artificial Tides, Winsor H. Watson Iii, Christopher C. Chabot, Stephen J. Skinner

Jackson Estuarine Laboratory

Limulus polyphemus, the American horseshoe crab, has an endogenous clock that drives circatidal rhythms of locomotor activity. In this study, we examined the ability of artificial tides to entrain the locomotor rhythms of Limulus in the laboratory. In experiments one and two, the activity of 16 individuals of L. polyphemus was monitored with activity boxes and “running wheels.” When the crabs were exposed to artificial tides created by changes in water depth, circatidal rhythms were observed in animals exposed to 12.4-h “tidal” cycles of either water depth changes (8 of 8 animals) or inundation (7 of 8 animals). In experiment …

Observations Of High Frequency, Long Range Acoustic Propagation In A Harbor Environment, Michelle Weirathmueller, Thomas C. Weber, Larry A. Mayer

Center for Coastal and Ocean Mapping

The positioning and navigation of AUV's in harbor environments using underwater acoustics is complicated by shallow waters, long propagation distances, and complex oceanographic features. This paper reports on high frequency (40 kHz) acoustic measurements made in Portsmouth Harbor, NH, USA, which is an estuary containing several riverine inputs and a strong tidal flow (2+ knots). A one-way propagation experiment was conducted at the mouth of the harbor for propagation distances up to 100 water depths. Strong signatures of a variety of phenomenon were observed in the acoustic signal levels, including tidal heights and currents, turbulent mixing, and wind/wave action. The …

Caretaker Satisfaction With Law Enforcement Response To Missing Children., Heather Hammer, David Finkelhor, Richard Ormrod, Andrea J. Sedlack, Carol Bruce

Crimes Against Children Research Center

Examines satisfaction with law enforcement from the perspective of all primary caretakers who contacted police when one or more of their children experienced a qualifying episode in the Second National Incidence Studies of Missing, Abducted, Runaway, and Thrownaway Children (NISMART–2) National Household Survey of Adult Caretakers. This Bulletin is the eighth in the NISMART–2 series.

2008-08-01 Pca Treasurer's Report, Pennsylvania Counseling Association

PCA Treasurer’s Reports

No abstract provided.

Njit Highlanders Women's Volleytball 2008 Media Guide, New Jersey Institute Of Technology Athletic Department

Volleyball - Women's

No abstract provided.

Dead Cores Of Singular Dirichlet Boundary Value Problems With Φ-Laplacian, Ravi P. Agarwal, Donal O'Regan, Svatoslav Staněk

Mathematics and System Engineering Faculty Publications

The paper discusses the existence of positive solutions, dead core solutions and pseudodead core solutions of the singular Dirichlet problem (ϕ(u′))′ = λf(t, u, u′), u(0) = u(T) = A. Here λ is the positive parameter, A > 0, f is singular at the value 0 of its first phase variable and may be singular at the value A of its first and at the value 0 of its second phase variable.

Efimov States Embedded In The Three-Body Continuum, Nirav P. Mehta, Seth T. Rittenhouse, J P. D’Incao, Chris H. Greene

Physics and Astronomy Faculty Research

We present analytical solutions for the three-body problem with multichannel interactions and identify a class of quasibound Efimov states that can be viewed as three-body Fano-Feshbach resonances. Our method employs a multichannel generalization of the Fermi pseudopotential to model low-energy atom-atom interactions near a magnetically tunable Fano-Feshbach resonance. We discuss the conditions under which quasibound Efimov states may be supported and identify the interaction parameters that limit the lifetimes of these states. We speculate that it may be possible to observe these states using spectroscopic methods, perhaps allowing for the measurement of multiple Efimov resonances.

Cell Wall-Bound Ultraviolet-Screening Compounds Explain The High Ultraviolet Tolerance Of The Antarctic Moss, Ceratodon Purpureus, L. J. Clarke, Sharon A. Robinson

Faculty of Science - Papers (Archive)

Studies of ultraviolet (UV) light-induced DNA damage in three Antarctic moss species have shown Ceratodon purpureus to be the most UV tolerant, despite containing lower concentrations of methanol-soluble UV-screening compounds than the co-occurring Bryum pseudotriquetrum. In this study, alkali extraction of cell wall-bound phenolics, combined with methanol extraction of soluble phenolics, was used to determine whether cell wall-bound UV screens explain the greater UV tolerance of C. purpureus. The combined pool of UV screens was similar in B. pseudotriquetrum and C. purpureus, but whilst B. pseudotriquetrum had almost equal concentrations of MeOH-soluble and alkali-extractable cell wall-bound UV-screening compounds, in C. …

Do Gpos Promote Or Stifle Competition In Healthcare-Product Supply Chains?, Qiaohai Hu, Leroy B. Schwarz

RCHE Publications

This paper uses economic modeling to examine the controversial role that Group Purchasing Organizations (GPOs) play in the supply chains for healthcare products. Among the controversies, perhaps the most fundamental one is whether or not GPO-contracted prices are the lowest available. However, the fiercest controversy is around the "Contract Administration Fees (CAFs)" that GPOs charge to manufacturers. We examine these and other controversies using a Hotelling duopoly model.