The Role Of Oral Microbiota In Periodontitis And Alzheimer's Disease,
2024
The University of Texas Rio Grande Valley
The Role Of Oral Microbiota In Periodontitis And Alzheimer's Disease, Noah Al-Hassan, Taha Al Hassan, Juan C. Lopez-Alvarenga, Maria Quinones, Seratna Guadarrama
Research Symposium
Background: Periodontal disease (PD), affecting 20-50% of the global population is marked by biofilm-induced inflammation in oral tissues. Chronic PD results in systemic complications such as heart disease, stroke, and Alzheimer's. The red complex microbes, Porphyromonas gingivalis and Treponema denticola, play a pivotal role, penetrating the blood-brain barrier and contributing to neurodegeneration. Alzheimer's disease (AD), an irreversible neurodegenerative disorder, is linked to abnormal protein cleavage and potentially involves microbiologic components, including gram-positive cocci. Research suggests the presence of bacteria such as Porphyromonas, Actinomyces, and Treponema in autopsied AD brains. Investigating the microbiologic connection between PD and AD is crucial, considering …
Who Benefits And How: Five Dimensions Of Adolescent Psychological Well-Being And Their Relative Impact On Cardiometabolic Health In Adulthood,
2024
Johns Hopkins University
Who Benefits And How: Five Dimensions Of Adolescent Psychological Well-Being And Their Relative Impact On Cardiometabolic Health In Adulthood, Farah Qureshi, Anna-Josee Guimond, Scott Delaney, Julia K. Boehm, Laura D. Kubzansky
Psychology Faculty Articles and Research
Purpose
Positive dimensions of psychological well-being in adolescence may help youth preserve cardiometabolic health (CMH) as they age, but little is known about which aspects of well-being matter most and for whom. This study examines the differential impact of five dimensions of adolescent psychological well-being on CMH maintenance in adulthood and considers social patterning in both their distribution and respective health benefits.Methods
Data were from the National Longitudinal Study of Adolescent Health (N = 3,464), five dimensions of psychological well-being were identified at baseline (1994–1995; mean age = 15 years): happiness, optimism, self-esteem, belonging, and feeling loved. CMH was …
Exploring The Neural Correlates Of Mindfulness-Based Interventions In Youth,
2024
Wayne State University
Exploring The Neural Correlates Of Mindfulness-Based Interventions In Youth, Jovan Jande, Clara Zundel, Samantha Ely, Sneha Bhargava, Carmen Carpenter, Reem Tamimi, Leah Gowatch, Mackenna Shampine, Emilie-Clare O'Mara, Shravya Chanamolu, Hilary Marusak
Medical Student Research Symposium
Mindfulness based interventions (MBI) reduce the severity of anxiety and depression among a variety of populations. While the psychological benefits of MBIs are increasingly recognized, less is known about the underlying neural correlates—particularly during childhood and adolescence, a time when many psychopathologies begin to emerge. Here, we provide the first systematic review on the neural correlates of MBI in youth. We reviewed the PubMed database for original articles examining the neural correlates of MBI in youth (0-18 years) leveraging neuroimaging. The search yielded 331 studies, of which 13 were included in the review. These studies comprised 451 participants and were …
Dhea: A Neglected Biological Signal That May Affect Fetal And Child Development,
2024
University of Virginia
Dhea: A Neglected Biological Signal That May Affect Fetal And Child Development, Natasha A. Bailey, Elysia Poggi Davis, Curt A. Sandman, Laura M. Glynn
Psychology Faculty Articles and Research
The stress-sensitive maternal hypothalamic–pituitary–adrenal (HPA) axis through the end-product cortisol, represents a primary pathway through which maternal experience shapes fetal development with long-term consequences for child neurodevelopment. However, there is another HPA axis end-product that has been widely ignored in the study of human pregnancy. The synthesis and release of dehydroepiandosterone (DHEA) is similar to cortisol, so it is a plausible, but neglected, biological signal that may influence fetal neurodevelopment. DHEA also may interact with cortisol to determine developmental outcomes. Surprisingly, there is virtually nothing known about human fetal exposure to prenatal maternal DHEA and offspring neurodevelopment. The current study …
General Cognitive Ability In High School, Attained Education, Occupational Complexity, And Dementia Risk,
2024
University of Southern California
General Cognitive Ability In High School, Attained Education, Occupational Complexity, And Dementia Risk, Jimi Huh, Thalida Em Arpawong, Tara L. Gruenewald, Gwenith G. Fisher, Carol A. Prescott, Jennifer J. Manly, Dominika Seblova, Ellen E. Walters, Margaret Gatz
Psychology Faculty Articles and Research
INTRODUCTION
We address the extent to which adolescent cognition predicts dementia risk in later life, mediated by educational attainment and occupational complexity.
METHODS
Using data from Project Talent Aging Study (PTAS), we fitted two structural equation models to test whether adolescent cognition predicts cognitive impairment (CI) and Ascertain Dementia 8 (AD8) status simultaneously (NCognitive Assessment = 2477) and AD8 alone (NQuestionnaire = 6491) 60 years later, mediated by education and occupational complexity. Co-twin control analysis examined 82 discordant pairs for CI/AD8.
RESULTS
Education partially mediated the effect of adolescent cognition on CI in the cognitive assessment aample and …
Infant Hedonic/Anhedonic Processing Index (Hapi-Infant): Assessing Infant Anhedonia And Its Prospective Association With Adolescent Depressive Symptoms,
2024
Chapman University
Infant Hedonic/Anhedonic Processing Index (Hapi-Infant): Assessing Infant Anhedonia And Its Prospective Association With Adolescent Depressive Symptoms, Jessica L. Irwin, Elysia Poggi Davis, Curt A. Sandman, Tallie Z. Baram, Hal S. Stern, Laura M. Glynn
Psychology Faculty Articles and Research
Background
Anhedonia, an impairment in the motivation for or experience of pleasure, is a well-established transdiagnostic harbinger and core symptom of mental illness. Given increasing recognition of early life origins of mental illness, we posit that anhedonia should, and could, be recognized earlier if appropriate tools were available. However, reliable diagnostic instruments prior to childhood do not currently exist.
Methods
We developed an assessment instrument for anhedonia/reward processing in infancy, the Infant Hedonic/Anhedonic Processing Index (HAPI-Infant). Exploratory factor and psychometric analyses were conducted using data from 6- and 12-month-old infants from two cohorts (N = 188, N = 212). …
Asl-English Interpreters And Anxiety,
2024
Clemson University
Asl-English Interpreters And Anxiety, Stephen B. Fitzmaurice, Meri Faulkner
Journal of Interpretation
Reflective of the American population, there are a number of interpreters who have Generalized Anxiety Disorder. Using a mixed methods approach, credentialed interpreters share their experience with anxiety as a professional interpreter. Participants relate both the positive and negative effects of anxiety on their interpreting work. Several anxiety coping strategies are explored, as well as, detailing the importance of finding a confidant. Issues such as potential professional stigma and the consequences of declining assignments for anxiety reasons are discussed.
Attitudes And Barriers To Breastfeeding Among Women At High-Risk For Not Breastfeeding: A Prospective Observational Study,
2024
Louisiana State University Health and Sciences Center, Baton Rouge, LA
Attitudes And Barriers To Breastfeeding Among Women At High-Risk For Not Breastfeeding: A Prospective Observational Study, Jessica Cole, Ateshi Bhatt, Andrew G. Chapple, Sarah Buzhardt, Elizabeth F. Sutton
School of Medicine Faculty Publications
Background Rates of breastfeeding are lower among minority and underserved populations in the United States. Our study objective was to assess pregnant persons attitudes and barriers to breastfeeding among a cohort at high risk for not breastfeeding. Methods We disseminated the Iowa Infant Feeding Attitude Scale (IIFAS) to 100 pregnant persons at least 18 years of age attending a prenatal visit in a low-resource, academic practice in south-central Louisiana (Woman’s Hospital). The IIFAS, as well as questions collecting information on breastfeeding experience and sociodemographic characteristics, were administered via interview. Medical records were reviewed to investigate associations between attitudes about breastfeeding …
Ghostlight,
2024
University of Kent at Canterbury - U.K.
Ghostlight, Christopher R. Deacy
Journal of Religion & Film
This is a film review of Ghostlight (2024), directed by Kelly O'Sullivan.
Digital Phobia: An Inquiry For Mapping The Unseen Dimension Of New Digital Anxiety, The ‘Digiphobia’,
2024
Central University of South Bihar (CUSB)
Digital Phobia: An Inquiry For Mapping The Unseen Dimension Of New Digital Anxiety, The ‘Digiphobia’, Amarjit Kumar Singh ,Library Assistant, Md. Arshad Ali , Professional Assistant, Dr. Pankaj Mathur, Deputy Librarian,
Library Philosophy and Practice (e-journal)
Background: As technology continues to advance, individuals' interactions with digital platforms have become integral to daily life. Amidst this technological evolution, a novel concern emerges—Digital Phobia, hereafter referred to as “Digiphobia.” This phenomenon, although not previously explored in scholarly literature, necessitates an in-depth investigation due to its potential impact on individuals' well-being. Our research employs a two-step methodology to investigate its existence, implications, and manifestations.
Introduction: This research paper introduces and proposes the term "Digiphobia" as a comprehensive conceptualization of anxiety arising from interactions with digital spaces, applications, and environments. The proliferation of digital technologies has led to the emergence …
Associations Between Genetically Predicted Plasma Protein Levels And Alzheimer’S Disease Risk: A Study Using Genetic Prediction Models,
2024
The Texas Medical Center Library
Associations Between Genetically Predicted Plasma Protein Levels And Alzheimer’S Disease Risk: A Study Using Genetic Prediction Models, Jingjing Zhu, Shuai Liu, Keenan A Walker, Hua Zhong, Dalia H Ghoneim, Zichen Zhang, Praveen Surendran, Sarah Fahle, Adam Butterworth, Md Ashad Alam, Hong-Wen Deng, Chong Wu, Lang Wu
Faculty, Staff and Student Publications
BACKGROUND: Specific peripheral proteins have been implicated to play an important role in the development of Alzheimer's disease (AD). However, the roles of additional novel protein biomarkers in AD etiology remains elusive. The availability of large-scale AD GWAS and plasma proteomic data provide the resources needed for the identification of causally relevant circulating proteins that may serve as risk factors for AD and potential therapeutic targets.
METHODS: We established and validated genetic prediction models for protein levels in plasma as instruments to investigate the associations between genetically predicted protein levels and AD risk. We studied 71,880 (proxy) cases and 383,378 …
Unveiling The State Of Loneliness: An Investigation Of Loneliness Patterns In Generation Z Undergraduates Across Tennessee,
2024
Belmont University
Unveiling The State Of Loneliness: An Investigation Of Loneliness Patterns In Generation Z Undergraduates Across Tennessee, Arwen Rolinitis, Alden Laborde, Jordan Osborne
[Archive] Belmont University Research Symposium (BURS)
The current study seeks to investigate the prevalence of loneliness in Generation Z undergraduates currently attending universities in Tennessee. Loneliness has been identified as a growing worldwide problem (United States Office of the Surgeon General, 2021), and given the continuing increase of loneliness in young adults (Buecker, 2021), it is evident that there is much left to learn regarding the personal experience of loneliness in modern undergraduates. To investigate the experience and prevalence of loneliness in Generation Z undergraduates, we conducted a survey with participants from one private and one public university in Tennessee. Participants completed a survey on Qualtrics …
Outpatient Fall Prevention In Ambulatory Adults 65 Years Old And Over,
2024
University of Texas at Arlington
Outpatient Fall Prevention In Ambulatory Adults 65 Years Old And Over, Dorothy L. Osborne-White
Doctor of Nursing Practice (DNP) Scholarly Projects - Archive
Background: In the United States (U.S.), falls are the leading cause of injury among adults 65 and over, resulting in 36 million falls yearly (Moreland et al., 2020). According to the Centers for Disease Control and Prevention (CDC, 2023), one in four older adults experiences a fall each year. Falls are the world's second most prominent cause of accidental deaths (World Health Organization [WHO], 2021). Falls are the leading cause of both fatal and non-fatal injuries among older adults (Moreland et al., 2020).
Methods: A quality improvement project that included a fall bundle was implemented in a primary clinic. A …
Identifying Youth Appeals In Alcohol Alternative Social Media Content Through Framing,
2024
West Chester University
Identifying Youth Appeals In Alcohol Alternative Social Media Content Through Framing, Melina Oneal
West Chester University Master’s Theses
Proposed regulations for alcohol advertising prevent beverage companies from targeting people under the legal drinking age. However, similar regulations for alcohol alternative beverages are less explored, which could allow alcohol alternative products to create awareness for alcoholic beverages among youth. Alcohol alternatives beverages, including no-alcohol and low-alcohol products, are increasing in popularity and can function as compliments to alcoholic products to decrease the total alcohol volume consumed or as substitutes for alcoholic products. Framing theory can be operationalized through the Content Appealing to Youth Index, an index of content elements found in research literature to be appealing to youth, to …
Clinical Practice Guideline For The Management Of Depression In Primary Care,
2024
University of Texas at Arlington
Clinical Practice Guideline For The Management Of Depression In Primary Care, Estrella Catherine Villarreal
Doctor of Nursing Practice (DNP) Scholarly Projects - Archive
Background: The prevalence of depression poses a significant challenge in primary care, emphasizing the urgent need to address this issue during patient visits. Primary care providers are at the forefront of managing depression, yet they encounter difficulties in screening, diagnosing, assessing, and treating this complex condition. Clinical guidelines serve as valuable tools for primary care providers and practices, offering support in identifying and addressing depression effectively. An evidence-based approach to treating depression in primary care, with a focus on collaborative interventions with behavioral health to enhance depression management for American Indian/Alaskan Native (AI/AN) communities.
Methods: The descriptive analysis was conducted …
Guideline For Creating A Support Group For Adults With Down Syndrome Who Suffer With Prolonged Grief,
2024
University of Texas at Arlington
Guideline For Creating A Support Group For Adults With Down Syndrome Who Suffer With Prolonged Grief, Brandon Chace Warman
Doctor of Nursing Practice (DNP) Scholarly Projects - Archive
Adults with Down syndrome process and express their grief differently from the general population. There are a multitude of support groups and organizations for individuals grieving a loss and experiencing prolonged grief but there are none that exist for people with Down syndrome. This project develops a guideline for creating support groups aimed at adults with Down syndrome who experience prolonged grief. Fifty-one pieces of literature from all over the world were reviewed to formulate recommendations that were graded by seven stakeholders. These recommendations were then used to develop a guideline for creating support groups for this population. Analysis of …
Genetic Knowledge And Causal Beliefs: Implications For Health Behavior In Clinical And Non-Clinical Samples,
2024
West Virginia University
Genetic Knowledge And Causal Beliefs: Implications For Health Behavior In Clinical And Non-Clinical Samples, Jamey T. Brumbaugh
Graduate Theses, Dissertations, and Problem Reports (ETD)
Objective: As the genomic era in healthcare continues to surge, it is vital to examine genetically-related psychological concepts, such as genetic knowledge and genetic causal beliefs, in genetically relevant clinical groups. Parents /caregivers of children born with cleft lip and/or palate represent a population whose knowledge and beliefs about genetics may be influenced by their frequent utilization of genetically-related healthcare services (e.g., genetic testing and genetic counseling). To date, little is known about how such beliefs vary across disease types. Even less is known regarding how disease-specific genetic causal beliefs relate to perceived behavioral control for disease development. Method: A …
The Unconscious Mind: Psychoanalysis And Art,
2024
Sotheby's Institute of Art
The Unconscious Mind: Psychoanalysis And Art, Carlie Hoffer
MA Theses
The insights brought to society about the unconscious mind can be solely credited to Sigmund Freud’s groundbreaking works that were published in the early 1900’s. Specifically, the concept of the unconscious mind being a driver for human behavior was a unique theory that Freud introduced to a society that had never considered this possibility before this. The realization and acknowledgement of the unconscious mind as relevant to analyzing human behavior including art inspired other scholars and individuals in the field of psychology to explore a more nuanced understanding of human motivations. His novel ideas about human behavior emerged at a …
The Relationship Between Moral Thought-Action Fusion And Scrupulosity Across Judaism, Christianity, And Islam,
2024
West Virginia University
The Relationship Between Moral Thought-Action Fusion And Scrupulosity Across Judaism, Christianity, And Islam, Kelsey Evey
Graduate Theses, Dissertations, and Problem Reports (ETD)
Scrupulosity is a subtype of obsessive-compulsive disorder (OCD) where individuals are upset by intrusive thoughts related to religious or moral issues. Current research suggests that scrupulosity occurs across the major world religions—including the Abrahamic religions (i.e., Judaism, Christianity, and Islam). Some research suggests that moral thought-action fusion (moral TAF), a dysfunctional belief that thinking something is equal to doing it, may only be pathological under certain circumstances (e.g., if it is not culturally normative). If this is true, the current cognitive model of scrupulosity may need to be amended to reflect how cultural differences impact the role of moral TAF …
Associations Between Positive Affect And Physical Activity From Young Adulthood To Midlife: A 25-Year Prospective Study,
2024
Johns Hopkins University
Associations Between Positive Affect And Physical Activity From Young Adulthood To Midlife: A 25-Year Prospective Study, Farah Qureshi, Laura D. Kubzansky, Ying Chen, Jackie Soo, Eric S. Kim, Donald Lloyd-Jones, Julia K. Boehm
Psychology Faculty Articles and Research
Objective: Positive affect may influence health by promoting physical activity, but evidence evaluating this association is mostly cross-sectional and cannot discern directionality. This study used a counterfactual-based framework to estimate the causal effect of positive affect on physical activity patterns over 25 years, accounting for potential reverse associations. Method: Data were from 3,352 participants in the Coronary Artery Risk Development in Young Adults study. Repeated assessments of positive affect and physical activity were collected from 1990 to 2016. Longitudinal associations were evaluated in two ways: (a) using baseline positive affect in traditional linear mixed models that accounted for reverse causal …
