Psychiatry and Psychology Commons^™

Authoritarian Parenting Predicts Callous-Unemotional Behaviors In Preschoolers, Ara Nazmiyal, Alli Hollender

Undergraduate Research Symposium Posters

Callous-unemotional behaviors, such as lack of empathy and guilt, are critical in understanding the development of certain mental pathologies. Studies have found that these traits are risk factors for disorders such as sociopathy and psychopathy. Virtually no studies have examined callous behaviors in the preschool period. The purpose of this study was to examine parenting characteristics that predict preschoolers’ greater callous-unemotional behaviors. This study examined data from the PCIT-ED study, a randomized control trial (RCT) of a novel treatment for depression for children aged 3.11-6.11 years old (N = 240). Callous behaviors were assessed by previously validated measures such …

Pilot Gwas Of Caries In African-Americans Shows Genetic Heterogeneity, E. Orlova, J. C. Carlson, M. K. Lee, E. Feingold, D. W. Mcneil, R. J. Crout, R. J. Weyant, M. L. Marazita, J. R. Shaffer

Faculty & Staff Scholarship

Background

Dental caries is the most common chronic disease in the US and disproportionately affects racial/ethnic minorities. Caries is heritable, and though genetic heterogeneity exists between ancestries for a substantial portion of loci associated with complex disease, a genome-wide association study (GWAS) of caries specifically in African Americans has not been performed previously.

Methods

We performed exploratory GWAS of dental caries in 109 African American adults (age > 18) and 96 children (age 3–12) from the Center for Oral Health Research in Appalachia (COHRA1 cohort). Caries phenotypes (DMFS, DMFT, dft, and dfs indices) assessed by dental exams were tested for association …

Discovery Of Novel Pharmacotherapeutics For Substance Use Disorders, Na-Ra Lee

Theses and Dissertations--Pharmacy

Substance use disorders are serious health concerns in the United States. Furthermore, the National Survey on Drug Use and Health reports a continuous increase in substance use disorders in the United States during the last 10 years. However, there are not many effective pharmacotherapeutics available for substance use disorders. The current dissertation is focused on research aimed at discovering pharmacotherapeutics for substance use disorders. First part of dissertation focused on discovering methamphetamine (METH) use disorder therapeutics targeting specific mechanism of METH action on dopaminergic neurons. The second part of dissertation focused on opioids and cocaine use disorder therapeutics targeting rewarding …

The Rorschach’S (R-Pas) Capacity To Predict Quality Of The Working Alliance, Jordan G. Stewart

Antioch University Dissertations & Theses

The aim of this study was to explore the Rorschach’s ability to predict the working alliance by investigating associations between specific Rorschach Performance Assessment System (R-PAS) variables and the Goals, Tasks, and Bonds dimensions of the Working Alliance Inventory (WAI). Specific R-PAS variables were chosen based their theoretical relatedness to the three dimensions of the WAI. The linear multiple regression results trended toward significance within the Goals domain, with the Human Movement Proportion score (M/MC) significantly predicting individual’s initial WAI Goals scores, indicating that individuals who possibly have difficulty modulating their emotions and tend to be more reactive in their …

The Anonymity Heuristic: How Surnames Stop Identifying People When They Become Trademarks, Russell W. Jacobs

Dickinson Law Review (2017-Present)

This Article explores the following question central to trademark law: if a homograph has both a surname and a trademark interpretation will consumers consider those interpretations as intrinsically overlapping or the surname and trademark as completely separate and unrelated words? While trademark jurisprudence typically has approached this question from a legal perspective or with assumptions about consumer behavior, this Article builds on the Law and Behavioral Science approach to legal scholarship by drawing from the fields of psychology, linguistics, economics, anthropology, sociology, and marketing.

The Article concludes that consumers will regard the two interpretations as separate and unrelated, processing surname …

How College Students Discuss Their Relationships, John R. Domenico

Honors Theses and Capstones

It is a statistically significant fact that individuals who identify as homosexual are more likely to experience intimate partner violence (IPV.) Despite this, statistically, it is less likely for those who identify as homosexual to report IPV to healthcare clinicians or to law enforcement. “How College Students Discuss their Relationships” examines the implications of intimate partner violence in college students who identify as homosexual and the repercussions IPV may have on discussions with healthcare clinicians. By performing semi-structured interviews with individuals who identify as homosexual on the UNH campus, mental health outcomes of emotional intimate partner violence in …

Informational And Educational Support For American Women During Labor And Delivery, Camille Hildebrand

Student Research Posters

The CDC recorded an increase from 7.2 maternal deaths per 100,000 live births in 1987 to 18.0 maternal deaths per 100,000 live births in 2014 with 60% of those being preventable (Reproductive Health, 2018). Birthing a child can be a significant and emotional experience (Hans et al., 2013). Unfortunately, continuous support during labor and delivery has become a privilege instead of a basic right in a hospital setting (Hodnett, Gates, Hofmeyr, & Sakala, 2005). A study on doula support during labor and delivery showed that women feel there is a lack of information being provided by medical staff in a …

The Use Of Dhea In The Treatment Of Depression, Bryan Tipton

Physician Assistant Scholarly Project Posters

Dehydroepiandrosterone (DHEA) and its sulfated ester (DHEA-S) are important pre-hormones that also have direct neurohormonal effects on the central nervous system. Over the last twenty years, data have revealed that serum DHEA peaks in a person’s mid-20s and steadily declines throughout their lifetime. In addition, women tend to have lower values than men. This is of note because lower serum values tend to be correlated with increased risk of depression, worse depressive symptoms, and increased risk of relapse into depression. A review of literature concerning DHEA’s age related values, its association with depression, and its use in the treatment of …

Apoa-I Deficiency Increases Cortical Amyloid Deposition, Cerebral Amyloid Angiopathy, Cortical And Hippocampal Astrogliosis, And Amyloid-Associated Astrocyte Reactivity In App/Ps1 Mice, Emily B. Button, Guilaine K. Boyce, Anna Wilkinson, Sophie Stukas, Arooj Hayat, Jianjia Fan, Brennan J. Wadsworth, Jerome Robert, Kris M. Martens, Cheryl L. Wellington

Faculty & Staff Scholarship

Background

Alzheimer’s disease (AD) is defined by amyloid beta (Aβ) plaques and neurofibrillary tangles and characterized by neurodegeneration and memory loss. The majority of AD patients also have Aβ deposition in cerebral vessels known as cerebral amyloid angiopathy (CAA), microhemorrhages, and vascular co-morbidities, suggesting that cerebrovascular dysfunction contributes to AD etiology. Promoting cerebrovascular resilience may therefore be a promising therapeutic or preventative strategy for AD. Plasma high-density lipoproteins (HDL) have several vasoprotective functions and are associated with reduced AD risk in some epidemiological studies and with reduced Aβ deposition and Aβ-induced inflammation in 3D engineered human cerebral vessels. In mice, …

Investigating Neurogenesis As A Veritable Epigenetic Endophenotype For Alzheimer's Disease, Layne Wells

Scripps Senior Theses

Alzheimer's disease (AD) is the most common neurodegenerative disease, characterized by progressive amyloid plaque aggregation, neurofibrillary tangles, and cortical tissue death. As the prevalence of AD is projected to climb in coming years, there is a vested interest in identifying endophenotypes by which to improve diagnostics and direct clinical interventions. The risk for complex disorders, such as AD, is influenced by multiple genetic, environmental, and lifestyle factors. Significant strides have been made in identifying genetic variants linked to AD through the genome-wide association study (GWAS). It has been estimated in more recent years, however, that GWAS-identified variants account for limited …

Lung Cancer Screening In A Community Setting: Characteristics, Motivations, And Attitudes Of Individuals Being Screened, Margaret M. Byrne, Sarah E. Lillie, Jamie L. Studts

Behavioral Science Faculty Publications

We describe the characteristics of individuals being screened in community settings including factors influencing screening decisions and the level of information sought prior to screening. Individuals from two community-based radiology clinics (N = 27) were surveyed after screening. Screening efficacy and salience were the most important factors in screening decisions, whereas healthcare provider recommendations were rated not important. Half of participants reported no or little conversation about screening with their primary care provider, and 61.5 percent had not sought any information on screening. Individuals being screened in a community setting are unlikely to have sufficient information for an informed …

Integrating Alexander Technique Into Treatment Of Adolescent Idiopathic Scoliosis To Improve Patient Quality Of Life, Ana Nishioka

Scripps Senior Theses

The following thesis posits training in the Alexander Technique as a possible solution to address the comorbidities of poor body image and reduced feelings of efficacy in patients treated for adolescent idiopathic scoliosis (AIS). Both literature and personal accounts of AIS highlight that current conservative methods of treating AIS offered by the Western medical sphere, including observation, bracing, and physical therapy, do not adequately address, and may actually exacerbate, negative mental health symptoms. Patients are often represented as their external orthopedic diagnosis and receive limited emotional guidance in exploring their internal feelings about their body and its capabilities. Alexander Technique …

Relations Among Maternal And Paternal Behavior And Children's Stress Biology, S.K. Jiaming Lin, Stacey N. Doan, John Milton

Scripps Senior Theses

Parenting behavior has been shown to have a wide range of effects, influencing children’s psychological and biological stress outcomes. Most research focuses on maternal parenting behaviors, with few studies observing the effects of paternal behaviors or the influence of both parents on their children. In this study, the relationship between maternal and paternal parenting behaviors was examined in its association to predict children’s cortisol levels. Cultural differences in parenting styles was also observed. American (N=86) and Chinese (N=97) families participated in the study, with parents reporting their behaviors. Children’s cortisol was collected during a stressor task and correlational analysis was …

Effects Of Multisensory Stop Signals On Sensitivity To Alcohol-Induced Disinhibition In Drinkers With Adhd, Alexandra R. D'Agostino

Theses and Dissertations--Psychology

Multisensory environments facilitate behavioral functioning in humans. The redundant signal effect (RSE) refers to the observation that individuals respond more quickly to stimuli when information is presented as multisensory, redundant stimuli rather than as a single stimulus presented to either modality alone. Our studies show that the disinhibiting effects of alcohol are attenuated when stop signals are multisensory versus unisensory. The present study expanded on this research to test the degree to which multisensory stop signals could also attenuate the disinhibiting effects of alcohol in those with attention-deficit hyperactivity disorder (ADHD), a clinical population characterized by poor impulse control. The …

Depressive Symptoms In Older Versus Younger People With Epilepsy: Findings From An Integrated Epilepsy Self-Management Clinical Research Dataset, Zaira Khalid, Hasina Momotaz, Farren Briggs, Kristin A. Cassidy, Betsy K. Wilson, Martha Sajatovic

Faculty Scholarship

Aim: There are limited data on psychological outcomes in older people with epilepsy (PWE). This analysis, from a large pooled dataset of clinical studies from the Managing Epilepsy Well (MEW) Network, examined clinical variables including depressive symptom severity, quality of life and epilepsy self-management competency among older (age 55+) vs younger (

Is Acetyl-L-Carnitine Effective And Safe In Treating Children With Adhd?, Kirstie Dominique

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this systematic review is to see how effective and safe is Acetyl-L-Carnitine in treating children with ADHD.

Study Design: This systematic review evaluated 3 randomized, controlled and double blind articles all published in English, which were published in peer-reviewed journals. The articles were found on PubMed through PCOM’s library website.

Outcomes measured: This review assessed how safe and effective ALC would be in treating children with ADHD. The outcomes were measured using the Parent and Teacher ADHD Scale IV, Conners’ Global Index-Parents Scale, Conners’ Global Index – Teachers Scale and the Vineland scores …

Does Sertraline Decrease Depression In Patients Who Suffered A Traumatic Brain Injury (Tbi)?, Christina Costantino

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not “Does sertraline decrease depression in patients who suffered a traumatic brain injury (TBI)?”

STUDY DESIGN: Review of three randomized controlled trials (RCTs) published in English between 2009-2016.

DATA SOURCES: One RCT and two double-blind, placebo-controlled, RCTs found via PubMed evaluated the benefit of the antidepressant drug, sertraline (Zoloft), in decreasing depression in patients who suffered a TBI.

OUTCOMES MEASURED: Main outcomes were measured using the DSM-IV, Hamilton Rating Score for Depression (HAM-D)6 , Beck Anxiety Inventory (BAI)6 , and the Life-3 quality of life (QOL)6 , …

Is Curcumin An Effective Treatment For Major Depressive Disorder?, Virginia Hoptman

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not curcumin is an effective treatment for Major Depressive Disorder (MDD).

STUDY DESIGN: A systematic review of three peer-reviewed studies published between 2014 and 2017.

DATA SOURCES: Two of the studies were randomized, double-blind, and placebo controlled. The third study was a randomized controlled trial. All three studies were chosen due to relevance to the clinical question and if they included patient oriented outcomes. The studies were found using PubMed.

OUTCOMES MEASURED: The outcomes of the studies were measured using self-report scales on each patient’s mood. The …

Is The Use Of Omega-3 Polyunsaturated Fatty Acids As Adjunctive Therapy Effective In Reducing Symptom Severity In Adult Schizophrenia Patients?, Desiree Goenaga

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective EBM review is to determine whether or not the use of omega-3 polyunsaturated fatty acids (PUFA) as adjunctive therapy is effective in reducing symptom severity in adult schizophrenia patients.

STUDY DESIGN: A selective review of three peer-reviewed, double-blind, randomized, placebo-controlled trials published between the years of 2008 and 2016.

DATA SOURCES: All three randomized control trials were published in English and were selected from peer-reviewed journals via EmBase and PubMed based on relevance to the clinical question posed above and that the outcomes measured in the studies mattered to patients, or were “patient oriented.” …

Does Metacognitive Training Improve The Quality Of Life In Patients With Schizophrenia?, Amy Wei

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not “Does metacognitive training (MCT) improve the quality of life in patients with schizophrenia?”

Study Design: Systematic review of three randomized controlled trials (RCTs) published in peer-reviewed journals between 2010-2014, all in the English language; two of which were published in 2014 and one in 2010.

Data Sources: Three randomized controlled trials found using PubMed.

Outcomes Measured: Quality of life with a focus on social relationships was assessed using the Brief Quality of Life Questionnaire of the World Health Organization (WHOQOL-BREF) or Quality of Life Scale (QLS). …