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Distress Tolerance: Prospective Associations With Cognitive-Behavioral Therapy Outcomes In Adults With Posttraumatic Stress And Substance Use Disorders, Anka A Vujanovic, Heather E Webber, Shelby J McGrew, Charles E Green, Scott D Lane, Joy M Schmitz 2022 The Texas Medical Center Library

Distress Tolerance: Prospective Associations With Cognitive-Behavioral Therapy Outcomes In Adults With Posttraumatic Stress And Substance Use Disorders, Anka A Vujanovic, Heather E Webber, Shelby J Mcgrew, Charles E Green, Scott D Lane, Joy M Schmitz

Faculty, Staff and Student Publications

Distress tolerance (DT; perceived or actual ability to tolerate aversive physical or emotional states) is related to both posttraumatic stress disorder (PTSD) symptoms and substance use disorders (SUD). This investigation evaluates self-report and behavioral measures of DT as potential predictors of PTSD and SUD cognitive-behavioral therapy outcomes. Participants included 41 treatment-seeking adults (53.7% women; 73.2% African American; Mage= 44.90, SD = 9.68) who met at least four symptoms of DSM-5 PTSD and DSM-IV substance dependence, assessed via structured interviews. At baseline (pre-treatment), participants completed the Distress Tolerance Scale (DTS), Mirror-Tracing Persistence Task (MTPT), Breath Holding task, and Paced Auditory …


The Utilization And Validation Of The Human Factors Intervention Matrix And The Companion Assessment Tool Faces In The Development Of Novel Interventions, Victoria Lew 2022 Embry-Riddle Aeronautical University

The Utilization And Validation Of The Human Factors Intervention Matrix And The Companion Assessment Tool Faces In The Development Of Novel Interventions, Victoria Lew

Doctoral Dissertations and Master's Theses

The purpose of the current project was to utilize and validate the Human Factors Intervention Matrix (HFIX) and the companion assessment tool FACES regarding developing and ranking novel interventions. This was completed by 1. Uncovering whether brainstorming with HFIX generated a higher quantity, quality, and broader breadth of ideas compared to traditional brainstorming, and 2. Seeing whether the modality in which HFIX was utilized affected the quantity, quality, and breadth of ideas generated. This research employed a 2x2 between-subjects experimental design (n = 120) where participants were assigned to groups of three in one of the four conditions. Analyses …


Dose-Related Effects Of Ketamine For Antidepressant-Resistant Symptoms Of Posttraumatic Stress Disorder In Veterans And Active Duty Military: A Double-Blind, Randomized, Placebo-Controlled Multi-Center Clinical Trial, Chadi G Abdallah, John D Roache, Ralitza Gueorguieva, Lynnette A Averill, Stacey Young-McCaughan, Paulo R Shiroma, Prerana Purohit, Antoinette Brundige, William Murff, Kyung-Heup Ahn, Mohamed A Sherif, Eric J Baltutis, Mohini Ranganathan, Deepak D'Souza, Brenda Martini, Steven M Southwick, Ismene L Petrakis, Rebecca R Burson, Kevin B Guthmiller, Argelio L López-Roca, Karl A Lautenschlager, John P McCallin, Matthew B Hoch, Alexandar Timchenko, Sergio E Souza, Charles E Bryant, Jim Mintz, Brett T Litz, Douglas E Williamson, Terence M Keane, Alan L Peterson, John H Krystal 2022 The Texas Medical Center Library

Dose-Related Effects Of Ketamine For Antidepressant-Resistant Symptoms Of Posttraumatic Stress Disorder In Veterans And Active Duty Military: A Double-Blind, Randomized, Placebo-Controlled Multi-Center Clinical Trial, Chadi G Abdallah, John D Roache, Ralitza Gueorguieva, Lynnette A Averill, Stacey Young-Mccaughan, Paulo R Shiroma, Prerana Purohit, Antoinette Brundige, William Murff, Kyung-Heup Ahn, Mohamed A Sherif, Eric J Baltutis, Mohini Ranganathan, Deepak D'Souza, Brenda Martini, Steven M Southwick, Ismene L Petrakis, Rebecca R Burson, Kevin B Guthmiller, Argelio L López-Roca, Karl A Lautenschlager, John P Mccallin, Matthew B Hoch, Alexandar Timchenko, Sergio E Souza, Charles E Bryant, Jim Mintz, Brett T Litz, Douglas E Williamson, Terence M Keane, Alan L Peterson, John H Krystal

Staff and Researcher Publications

This study tested the efficacy of repeated intravenous ketamine doses to reduce symptoms of posttraumatic stress disorder (PTSD). Veterans and service members with PTSD (n = 158) who failed previous antidepressant treatment were randomized to 8 infusions administered twice weekly of intravenous placebo (n = 54), low dose (0.2 mg/kg; n = 53) or standard dose (0.5 mg/kg; n = 51) ketamine. Participants were assessed at baseline, during treatment, and for 4 weeks after their last infusion. Primary analyses used mixed effects models. The primary outcome measure was the self-report PTSD Checklist for DSM-5 (PCL-5), and secondary outcome …


Gender Dysphoria Versus Acute Psychosis: Can One Properly Diagnose Gender Dysphoria Solely During Acute Psychosis?, Kristy A. Fisher, Samantha Scemla, Clara L. Alvarez Villalba, Jessica Kroin 2022 HCA Florida Aventura Hospital

Gender Dysphoria Versus Acute Psychosis: Can One Properly Diagnose Gender Dysphoria Solely During Acute Psychosis?, Kristy A. Fisher, Samantha Scemla, Clara L. Alvarez Villalba, Jessica Kroin

HCA Healthcare Journal of Medicine

Gender dysphoria occurs when a discrepancy between one’s sex assigned at birth and one’s gender identity causes distress or impairment in function, which can lead ultimately to seeking treatment in the forms of psychotherapy, hormonal therapy, and/or gender-affirming surgery. Clinical care guidelines also recommend pharmacological treatment of psychiatric comorbidities if indicated. A review of the current literature demonstrates comorbidity between gender dysphoria and psychosis, including cases of gender dysphoria with schizophrenia and the occurrence of gender dysphoria symptoms during manic or psychotic episodes. The existing literature has yet to specifically examine gender dysphoria amongst individuals with schizoaffective disorder. The authors …


Covid-19 And Mental Health Disparities In The Black American Population, Israel Taylor 2022 HCA Florida Osceola Hospital

Covid-19 And Mental Health Disparities In The Black American Population, Israel Taylor

HCA Healthcare Journal of Medicine

The current COVID-19 pandemic has amplified health disparities that have long existed for minoritized groups in the United States. There have been disproportionate effects on the mental and physical health of the Black American population, specifically because of longstanding racial, social, and economic injustices. To fully understand the current state of Black mental health and the extent to which COVID-19 has impacted it, we examine historical examples of unjust mental health practices throughout generations. We then explore why depression, suicidality, and other mental illnesses may have a profound effect on a community that has been made vulnerable to socioeconomic shifts. …


Through The Cracks: The Disposition Of Patients With Schizophrenia Spectrum Disorders In The Post-Asylum Era, Briana Tillman, Erin Smith, Alicia Cho, Colt Kennington, Alexandra Kreis 2022 The Medical Center of Aurora

Through The Cracks: The Disposition Of Patients With Schizophrenia Spectrum Disorders In The Post-Asylum Era, Briana Tillman, Erin Smith, Alicia Cho, Colt Kennington, Alexandra Kreis

HCA Healthcare Journal of Medicine

This paper aims to explore current disposition options for patients with psychosis in light of shifts toward community care and changes in mental healthcare funding in the post-asylum era and to propose systemic-level improvements based upon local successes. It evaluates critiques of long-term psychiatric care programs, claims of transinstitutionalization to incarceration, shelters, and emergency rooms, and programs initiated to address deinstitutionalization. The authors conclude that while Assertive Community Treatment, Partial Hospitalization Programs, intermediate-level care, and housing interventions can improve outcomes for many persons with psychotic illness, a significant portion of these patients would still be best served in long-term psychiatric …


Psychological Well-Being In Childhood And Cardiometabolic Risk In Middle Adulthood: Findings From The 1958 British Birth Cohort, Julia K. Boehm, Farah Qureshi, Laura D. Kubzansky 2022 Chapman University

Psychological Well-Being In Childhood And Cardiometabolic Risk In Middle Adulthood: Findings From The 1958 British Birth Cohort, Julia K. Boehm, Farah Qureshi, Laura D. Kubzansky

Psychology Faculty Articles and Research

Childhood adversity is linked to poor cardiometabolic outcomes, but less is known about positive childhood factors. Using data from 4,007 members of the 1958 British Birth Cohort, we investigated whether children with greater psychological well-being had lower adulthood cardiometabolic risk. At age 11, participants wrote essays about their future. Two judges rated each essay for nine psychological well-being items (Finn’s r = .82–.91), which were combined into a standardized overall score (Cronbach’s α = .91). When participants reached age 45, nurses assessed their blood pressure, heart rate, lipids, glycosylated hemoglobin, fibrinogen, and C-reactive protein, which were standardized and summed for …


Profession Related Intra-Correlation Satisfaction Levels In Palestinian Physiotherapists: An Exploratory Study, Yousef Al Hamdan, Mosab Amoudi, Wael Abuhassan 2022 Arab American University, Palestine

Profession Related Intra-Correlation Satisfaction Levels In Palestinian Physiotherapists: An Exploratory Study, Yousef Al Hamdan, Mosab Amoudi, Wael Abuhassan

Journal of the Arab American University مجلة الجامعة العربية الامريكية للبحوث

Aim of Study: The aim of the present study was to investigate the level of job satisfaction of physiotherapists in Palestine and to how much extent those levels are intra-correlated.

Methods: Researchers used the cross-sectional descriptive analytical approach, where data was collected through a questionnaire. The target population was physiotherapists in Palestine. A sample of 60 physiotherapists was conveniently selected. Program of SPSS was used to analyze data, where means were extracted, in addition to percentages and standard deviations to answer study questions.

Results: The research results showed that the overall mean of the sample responses on …


Homoeopathy As An Add-On Treatment For Schizophrenia - A Case Series, S Karunakara Moorthi, Radhika P, Mohan N. Devasia 2022 National Homoeopathy Research Institute in Mental Health, Kottayam, Kerala, India

Homoeopathy As An Add-On Treatment For Schizophrenia - A Case Series, S Karunakara Moorthi, Radhika P, Mohan N. Devasia

Indian Journal of Research in Homoeopathy

Introduction: Schizophrenia is a complex, progressive and severe mental disorder characterised by distortions in thinking, perception, emotions, language, sense of self and behaviour. Conventional medication and cognitive behaviour therapy are used in the treatment of schizophrenia. Homoeopathy can also offer promising results in schizophrenia as evident from the previous studies. Case Summary: Five patients reported at the outpatient department of National Homoeopathy Research Institute in Mental Health, Kerala, India, with symptoms of schizophrenia were treated with individualised homoeopathic medicine as an add-on therapy to conventional medicines. Assessment of the patients was done using three scales: Positive and Negative Syndrome Scale, …


Phq-2 Scores In Broward County’S Homeless: Prevalence, Barriers, And Proposed Solutions To Mental Health Disparities, Jeena A. Kar, Reeja Raj, Ariba Hashmi, Tahia Hossain, Joshua Berko, Joseph S. DeGaetano, Patrick Hardigan 2022 University of Florida, Nova Southeastern University KCPCOM

Phq-2 Scores In Broward County’S Homeless: Prevalence, Barriers, And Proposed Solutions To Mental Health Disparities, Jeena A. Kar, Reeja Raj, Ariba Hashmi, Tahia Hossain, Joshua Berko, Joseph S. Degaetano, Patrick Hardigan

Cooper Rowan Medical Journal

Introduction: Florida ranks 9th in states with highest prevalence of mental illness among homeless individuals. The state also ranks 43rd of 52 states in providing adequate access for mental health concerns in homeless individuals. This study surveyed people experiencing homelessness in Broward County to investigate utilization of healthcare and mental health resources and accessibility of the target population to adequate care.. Aims included a collection of demographics concerning homelessness such as age and gender, prevalence of mental illness, history of substance use and emergency department, and then correlating these with scores from a standardized depression rating scale (PHQ-2). Methods: The …


Anxiety Symptoms Among Extension Professionals' During The Covid-19 Pandemic With The Gad-2, Glenn D. Israel, Colleen E. Gariton, Harsha E. James 2022 University of Florida

Anxiety Symptoms Among Extension Professionals' During The Covid-19 Pandemic With The Gad-2, Glenn D. Israel, Colleen E. Gariton, Harsha E. James

Journal of Rural Social Sciences

According to the National Institute of Mental Health, anxiety disorders are a common mental health disorder but often remain undetected and undertreated. During the COVID-19 pandemic, Extension professionals have worked hard to address emerging issues that communities face, possibly impacting the amount of anxiety they experience. This study determined the prevalence of anxiety symptoms among Extension professionals in the United States. Participants from 24 states completed a survey containing the Generalized Anxiety Disorder 2-item (GAD-2) screener. Almost one-quarter of Extension professionals had a GAD-2 score greater than three, an indicator of anxiety with a possibility of generalized anxiety disorder, which …


A Review On Psychosocial Distress Among General Population Of Pakistan During Covid-19 Pandemic, Anosh Arshad Chaudhary, Iqra Arooj, Amina Elahi 2022 Department of Microbiology & Molecular Genetics, The Women University, Multan, 60000, Pakistan.

A Review On Psychosocial Distress Among General Population Of Pakistan During Covid-19 Pandemic, Anosh Arshad Chaudhary, Iqra Arooj, Amina Elahi

Journal of Bioresource Management

The COVID-19 crisis in 2019 significantly impacted human life all over the globe. Psychological health of general population has been affected by the unpredictable circumstances and impulsion of living in isolation, if suspected positive for coronavirus. During COVID-19 outbreak, escalation of various types of psychosocial distresses such as anxiety, sleep disorders and depression has been observed in the general population globally. Thus, there is an urgent need to combat these issues through well planned strategies. The focus of this review is to conduct a thorough evaluation of the available research on the effects of COVID-19 pandemic on the mental status …


The Impact Of Trauma Subtypes On Ptsd Severity In Syrian Child And Adolescent Refugees, Liza Hinchey, Lana Grasser, Bassem Saad, Kathleen Gorski, Arash Javanbakht, May Chammaa 2022 Wayne State University

The Impact Of Trauma Subtypes On Ptsd Severity In Syrian Child And Adolescent Refugees, Liza Hinchey, Lana Grasser, Bassem Saad, Kathleen Gorski, Arash Javanbakht, May Chammaa

Medical Student Research Symposium

Background:

Child and adolescent refugee populations are at increased risk for psychiatric disorders including posttraumatic stress disorder (PTSD) and anxiety. Recent studies have demonstrated different symptomatology based on the type(s) of traumatic events experienced. Cluster analyses based on the Life Events Checklist (LEC) indicate three trauma subtypes: accidental/injury, victimization, and predominant death threat. Extending this line of research from adults to youth may lead to better understanding of the unique impacts of trauma subtypes on symptoms for improved prediction of risk and resilience.

Methods:

Refugee participants were recruited within 1 month of their resettlement in the U.S. Data used were …


Norepinephrine Regulation Of Spatial Memory Using The Barnes Maze In Male And Female Rats, Serena Simpson, Ali Gheidi PhD, Nareen Sadik, Cameron J. Davidson PhD, Shane A. Perrine PhD 2022 Wayne State University

Norepinephrine Regulation Of Spatial Memory Using The Barnes Maze In Male And Female Rats, Serena Simpson, Ali Gheidi Phd, Nareen Sadik, Cameron J. Davidson Phd, Shane A. Perrine Phd

Medical Student Research Symposium

The role of norepinephrine (NE) in learning and memory has been extensively studied, yet its contribution remains to be clarified. This study aimed to investigate the role of NE on spatial learning and memory in female and male rats using a Barnes maze assay. We used N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4), a specific noradrenergic neurotoxin that can cross the blood brain barrier, to deplete NE stores. We hypothesized that brain NE ablation would attenuate spatial learning and memory in rats. Loss of NE by DSP-4 was determined by measuring NE (and dopamine and serotonin) levels in several brain regions using HPLC. For the …


Individual Differences In The Criminogenic Effects Of Discrimination: An Exploration Of The Role Of Impulse Control And Callous-Unemotional Traits, Toni Walker 2022 Louisiana State University and Agricultural and Mechanical College

Individual Differences In The Criminogenic Effects Of Discrimination: An Exploration Of The Role Of Impulse Control And Callous-Unemotional Traits, Toni Walker

LSU Doctoral Dissertations

The association between perceived discrimination and engagement in criminal offending has been well studied, especially in samples of minority (predominantly Black, Hispanic, and Latinx) adolescents. Several theories have been developed (Social Schematic Theory) and adapted (General Strain Theory) in an attempt to explain how harmful, discriminatory experiences may have an effect on an individual’s behavior. There may be variability in how an individual responds to perceived discrimination, however, but the moderating role of personality characteristics has not been explored. Impulse control and callous-unemotional (CU) traits are both established predictors of offending and may also relate to the mechanisms that theories …


Mobile Health Applications For Postpartum Depression Management: A Theory-Informed Analysis Of Change-Use-Engagement (Cue) Criteria In The Digital Environment, Alexandra Zingg, Laura Carter, Deevakar Rogith, Sudhakar Selvaraj, Amy Franklin, Sahiti Myneni 2022 The Texas Medical Center Library

Mobile Health Applications For Postpartum Depression Management: A Theory-Informed Analysis Of Change-Use-Engagement (Cue) Criteria In The Digital Environment, Alexandra Zingg, Laura Carter, Deevakar Rogith, Sudhakar Selvaraj, Amy Franklin, Sahiti Myneni

Faculty, Staff and Student Publications

Postpartum Depression (PPD) is the most common childbirth complication, with approximately 15% of postpartum women experiencing depression symptoms. Mobile applications have potential to expand delivery of mental health interventions. However, our understanding of how these tools engage women with PPD and facilitate positive behavioral changes is limited. In our paper, we analyze 15 commercial PPD applications to understand their role as facilitators of change, engagement, and sustained use. Applications reviewed contained an average of four theory-based behavioral change techniques, and highest patient engagement level reached was to empower patients through patient-generated data. Heuristic violations were identified in areas including user …


The Role Of Reported Affective Symptoms And Anxiety In Recovery Trajectories After Sport-Related Concussion, Bernadette A. D'Alonzo, Abigail C. Bretzin, Douglas J. Wiebe, Ivy League–Big Ten Epidemiology of Concussion Study Investigators, Arthur C. Maerlender, Cary R. Savage 2022 University of Pennsylvania

The Role Of Reported Affective Symptoms And Anxiety In Recovery Trajectories After Sport-Related Concussion, Bernadette A. D'Alonzo, Abigail C. Bretzin, Douglas J. Wiebe, Ivy League–Big Ten Epidemiology Of Concussion Study Investigators, Arthur C. Maerlender, Cary R. Savage

Center for Brain, Biology, and Behavior: Faculty Publications

Background: There is growing awareness and clinical interest in athletes with affective symptoms after sport-related concussion (SRC), as these symptoms may contribute to overall symptoms and represent a modifiable risk factor of longer recovery. However, evidence of their effects on the entire return-to-play (RTP) trajectory, particularly among women and men, is limited.

Purpose/Hypothesis: To examine the relationship between affective symptom reporting and RTP progression after SRC among a cohort of Division 1 student-athletes. We hypothesized that those endorsing affective symptoms, specifically nervous-anxious symptoms, spend more time in RTP progression and recovery.

Study Design: Cohort study; Level of evidence, 3.

Methods: …


Age-Dependent White Matter Disruptions After Military Traumatic Brain Injury: Multivariate Analysis Results From Enigma Brain Injury, Heather C. Bouchard, Delin Sun, Emily L. Dennis, Mary R. Newsome, Seth G. Disner, Jeremy Elman, Annelise Silva, Carmen Velez, Andrei Irimia, Nicholas D. Davenport, Scott R. Sponheim, Carol E. Franz, William S. Kremen, Michael J. Coleman, M. Wright Williams, Elbert Geuze, Inga K. Koerte, Martha E. Shenton, Maheen M. Adamson, Raul Coimbra, Gerald Grant, Lori Shutter, Mark S. George, Ross D. Zafonte, Thomas W. McAllister, Murray B. Stein, Paul M. Thompson, Elisabeth A. Wilde, David F. Tate, Aristeidis Sotiras, Rajendra A. Morey 2022 Duke University & University of Nebraska-Lincoln

Age-Dependent White Matter Disruptions After Military Traumatic Brain Injury: Multivariate Analysis Results From Enigma Brain Injury, Heather C. Bouchard, Delin Sun, Emily L. Dennis, Mary R. Newsome, Seth G. Disner, Jeremy Elman, Annelise Silva, Carmen Velez, Andrei Irimia, Nicholas D. Davenport, Scott R. Sponheim, Carol E. Franz, William S. Kremen, Michael J. Coleman, M. Wright Williams, Elbert Geuze, Inga K. Koerte, Martha E. Shenton, Maheen M. Adamson, Raul Coimbra, Gerald Grant, Lori Shutter, Mark S. George, Ross D. Zafonte, Thomas W. Mcallister, Murray B. Stein, Paul M. Thompson, Elisabeth A. Wilde, David F. Tate, Aristeidis Sotiras, Rajendra A. Morey

Center for Brain, Biology, and Behavior: Faculty Publications

Mild Traumatic brain injury (mTBI) is a signature wound in military personnel, and repetitive mTBI has been linked to age-related neurogenerative disorders that affect white matter (WM) in the brain. However, findings of injury to specific WM tracts have been variable and inconsistent. This may be due to the heterogeneity of mechanisms, etiology, and comorbid disorders related to mTBI. Non-negative matrix factorization (NMF) is a data-driven approach that detects covarying patterns (components) within high-dimensional data. We applied NMF to diffusion imaging data from military Veterans with and without a self-reported TBI history. NMF identified 12 independent components derived from fractional …


Is The Phq-9 A Unidimensional Measure Of Depression? A 58,272-Participant Study, Renzo Bianchi, Jay Verkuilen, Sharon Toker, Irvin Sam Schonfeld, Markus Gerber, Elmar Brähler, Kurt Kroenke 2022 Norwegian University of Science and Technology

Is The Phq-9 A Unidimensional Measure Of Depression? A 58,272-Participant Study, Renzo Bianchi, Jay Verkuilen, Sharon Toker, Irvin Sam Schonfeld, Markus Gerber, Elmar Brähler, Kurt Kroenke

Publications and Research

The PHQ-9 has become a measure of reference in depression research and clinical practice. However, the issue of the PHQ-9’s unidimensionality has not been fully elucidated, and the usability of the PHQ-9’s total score requires clarification. In this study, we examined the dimensionality, scalability, and monotonicity properties of the PHQ-9 as well as the scale’s total-score reliability. We did so based on exploratory structural equation modeling (ESEM) bifactor analysis and Mokken scale analysis (MSA). We relied on a total of 58,272 participants (63% female; Mage = 43, SDage = 13) from 29 samples involving seven different countries (e.g., Germany, the …


Stress And Resilience Among Resettling Refugee Youth: An Illustrative Review And New Applications For The Family Stress Model, April S. Masarik, Hailey Fritz, Vanja Lazarevic 2022 Boise State University

Stress And Resilience Among Resettling Refugee Youth: An Illustrative Review And New Applications For The Family Stress Model, April S. Masarik, Hailey Fritz, Vanja Lazarevic

Psychological Sciences Faculty Publications and Presentations

Some of the world's 84 million forcibly displaced persons (approximately half are youth under the age of 18) obtain legal refugee status, which allows them passage to resettle in new communities. Although much has been documented about experiences of stress and trauma among refugees, we know less about their resilience and coping abilities. Furthermore, a lack of an overarching theoretical framework hinders our understanding of the complete refugee experience, which includes stressors, but also significant strengths and resources. In this paper, we offer a unified conceptual model inspired by family stress, ecological systems, and resilience science that outlines hypothesized stress …


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