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Does Exogenous Melatonin Improve Quality Of Sleep In Patients Experiencing Sleep Disturbances Secondary To Chronic Diseases?, Blessen B. Thomas 2016 Philadelphia College of Osteopathic Medicine

Does Exogenous Melatonin Improve Quality Of Sleep In Patients Experiencing Sleep Disturbances Secondary To Chronic Diseases?, Blessen B. Thomas

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not “Does exogenous melatonin improve quality of sleep in patients experiencing sleep disturbances secondary to chronic diseases?”

Study Design: Three Randomized, placebo-controlled studies (RCT) published in 2010, 2013 and 2008. Data Sources: All RCTs searched and located using PubMed database.

Outcomes Measured: Clinical outcome for all three articles using quality of sleep or quality of life questionnaires such as the Leeds Sleep Evaluation. All of which evaluated POEMs, and were self reported by participants.

Results: In a randomized control study (RCT) by Serfaty et al, sleep quality …


Does The Use Of Oral Amphetamines Reduce Cocaine Use In Cocaine-Dependent Individuals?, Kevin M. Strate 2016 Philadelphia College of Osteopathic Medicine

Does The Use Of Oral Amphetamines Reduce Cocaine Use In Cocaine-Dependent Individuals?, Kevin M. Strate

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of this selective EBM review is to determine whether or not the use of oral amphetamines reduces cocaine use in cocaine-dependent individuals.

Study Design: Review of three English language randomized control trials (RCTs) published in 2001, 2003 and 2004.

Data Sources: 3 randomized controlled trials published after 1999 were obtained using PubMed, OVID, and Medline.

Outcomes Measured: The efficacy of using d-amphetamine to promote cocaine use cessation in cocaine-dependent individuals, determined using immunoassay and mass spectrometric analysis to identify cocaine metabolites in the participant’s urine.

Results: Grabowski et al (2004) found a significant reduction in the use …


Is Dance/Movement Therapy An Effective Treatment For Depression In Students?, Jillian R. Ranker 2016 Philadelphia College of Osteopathic Medicine

Is Dance/Movement Therapy An Effective Treatment For Depression In Students?, Jillian R. Ranker

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this selective evidence-based medicine (EBM) review is to determine whether or not Dance/Movement Therapy (DMT) is an effective treatment for depression in students.

STUDY DESIGN: Systematic review of three published, randomized controlled trials (RCTs) between 2005 and 2013, all English language

DATA SOURCES: Three RCTs analyzing DMT use in depression were found using PudMed

OUTCOMES MEASURED: Decrease in depressive symptoms, measured by the Beck Depression Scale, a self-rated health questionnaire, and Symptom Check List-90-Revision (SCL- 90-R)

RESULTS: DMT resulted in lessened depressive symptoms for students in all three RCTs. Jeong et al. observed a significant decrease …


Is Incidence Of Nausea Influenced By Brintellix In Patients Over The Age Of 18 With Major Depressive Disorder?, Juris Eyler 2016 Philadelphia College of Osteopathic Medicine

Is Incidence Of Nausea Influenced By Brintellix In Patients Over The Age Of 18 With Major Depressive Disorder?, Juris Eyler

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The Objective of this selective EBM review is to determine where or not, “Is Incidence of Nausea Influenced by Brintellix (Vortioxetine) in Patients over the Age of 18 with Major Depressive Disorder (MDD)?”

STUDY DESIGN: Review of three English language primary studies, published between 2011 and 2013

DATA SOUCES: Three double blind randomized controlled trials (RCTs). Sources were found on PubMed and Cochrane Library databases.

OUTCOMES MEASURED: To measure the incidence of nausea in patients over 18 who are diagnosed with major depressive disorder taking Brintellix compared to a placebo.

RESULTS: The randomized controlled studies results found that Brintellix …


The “Burnout” Construct: An Inhibitor Of Public Health Action?, Bianchi Renzo, Irvin Sam Schonfeld, Eric Laurent 2016 Université de Neuchâtel

The “Burnout” Construct: An Inhibitor Of Public Health Action?, Bianchi Renzo, Irvin Sam Schonfeld, Eric Laurent

Publications and Research

The prevention and treatment of the “burnout syndrome” within the critical care community is an important objective of the Moss et al. Burnout in the occupational area is based on the idea that burnout is especially common in individuals who care for critically ill patients. We think that the authors’ observations and recommendations are diminished by the fact that studies of burnout’s prevalence are methodologically problematic. The current definition and use of the burnout construct may in fact be detrimental to public health decision making.


The Effect Of Pre-Deployment Physiology As A Predictor Of Post-Traumatic Stress Disorder Among A Sample Of United States Army National Guard And Reserve Soldiers, David J. Rothman 2016 Virginia Commonwealth University

The Effect Of Pre-Deployment Physiology As A Predictor Of Post-Traumatic Stress Disorder Among A Sample Of United States Army National Guard And Reserve Soldiers, David J. Rothman

Theses and Dissertations

Potential risk factors for development of Post-Traumatic Stress Disorder (PTSD) are still unclear. One potential risk factor for the development of PTSD is an individual’s cardiovascular reactivity and recovery in response to stressor tasks. The current study was conducted with 763 Army National Guard and Army Reserve soldiers. Participants completed a stressful induction along with self-report measures prior to deployment. Post-deployment, self-report measures were completed to assess PTSD symptomatology and experiences related to deployment and combat. Multiple regression was used to determine the ability of blood pressure response to stress to predict PTSD symptoms immediately and one-year after return from …


Subjective Measures Of Mz And Dz Twins During Anxiety-Provoking Tasks, Sravya Uppalapati 2016 Virginia Commonwealth University

Subjective Measures Of Mz And Dz Twins During Anxiety-Provoking Tasks, Sravya Uppalapati

Undergraduate Research Posters

Temporary anxiety is a healthy response to stress; however, continuous anxiety can threaten an individual’s day-to-day living by eliciting negative responses. In the study, monozygotic 84 (MZ) and 153 dizygotic (DZ) adolescent twins pairs, ages 15 to 20 years, participated in anxiety-provoking tasks and subjective experiences of anxiety were measured using subjective units of distress (SUDS). The twin participants were recruited through the Mid-Atlantic Twin Registry (MATR) at Virginia Commonwealth University. The twins participated in a carbon dioxide (CO2) breathing task and a trier social stress task (TSST). The study aims were to evaluate the relationship between anxiety-provoking …


The Relationship Between Exercise And Depression And Anxiety In College Students, Joshua Frank, Dr. Amy Adkins, Nathan Thomas, Dr. Danielle Dick 2016 Virginia Commonwealth University

The Relationship Between Exercise And Depression And Anxiety In College Students, Joshua Frank, Dr. Amy Adkins, Nathan Thomas, Dr. Danielle Dick

Undergraduate Research Posters

The literature shows an inverse association between exercise and mental disorders. The aim of this study is to further elaborate on this association with regards to exercise and its relationship with anxiety and depression in a college sample. The subject group focused on seniors in the Spit for Science data set which incorporated a total of 821 students. Physical activity was assessed using the International Physical Activity Questionnaire (IPAQ) to estimate the overall metabolic equivalents (MET’s) each student spent in walking, moderate, or vigorous activity levels in the previous week. Sum scores were used to measure depression and anxiety. Overall,the …


Parsing The Behavioral And Brain Mechanisms Of Third-Party Punishment, Owen D. Jones, Matthew Ginther, Richard J. Bonnie, Morris B. Hoffman, Francis X. Shen, Kenneth W. Simons, Rene Marois 2016 Court of Federal Claims

Parsing The Behavioral And Brain Mechanisms Of Third-Party Punishment, Owen D. Jones, Matthew Ginther, Richard J. Bonnie, Morris B. Hoffman, Francis X. Shen, Kenneth W. Simons, Rene Marois

Vanderbilt Law School Faculty Publications

The evolved capacity for third-party punishment is considered crucial to the emergence and maintenance of elaborate human social organization and is central to the modern provision of fairness and justice within society. Although it is well established that the mental state of the offender and the severity of the harm he caused are the two primary predictors of punishment decisions, the precise cognitive and brain mechanisms by which these distinct components are evaluated and integrated into a punishment decision are poorly understood.

Using a brain-scanning technique known as functional magnetic resonance imaging (fMRI), we implemented a novel experimental design to …


“The Most Poisonous Of All Diseases Of Mind Or Body”: Colorphobia And The Politics Of Reform, April J. Gemeinhardt 2016 University of Montana

“The Most Poisonous Of All Diseases Of Mind Or Body”: Colorphobia And The Politics Of Reform, April J. Gemeinhardt

Graduate Student Theses, Dissertations, & Professional Papers

Focusing on the mid-1830s through 1865, this thesis explores colorphobia—the irrational fear and hatred of black people otherwise known as racial prejudice—as a reform tactic adopted by abolitionists. It argues that colorphobia played a pivotal role in the radical abolitionist reform agenda for promoting anti-slavery, immediate emancipation, equal rights, and black advancement. By framing racial prejudice as a disease, abolitionists believed connotations, stigmas, and fears of illness would elicit more attention to the rapidly increasing racial prejudice in the free North and persuade prejudiced white Americans into changing their ways. Abolitionists used parallels to cholera, choleraphobia (fear of cholera), and …


Burnout And Depression: Two Entities Or One, Irvin Sam Schonfeld, Renzo Bianchi 2016 CUNY Graduate Center

Burnout And Depression: Two Entities Or One, Irvin Sam Schonfeld, Renzo Bianchi

Publications and Research

Objectives: The purpose of this study was to examine the overlap in burnout and depression. Method: The sample comprised 1,386 schoolteachers (mean age = 43; mean years taught = 15; 77% women) from 18 different U.S. states. We assessed burnout, using the Shirom-Melamed Burnout Measure, and depression, using the depression module of the Patient Health Questionnaire. Results: Treated dimensionally, burnout and depressive symptoms were strongly correlated (.77; disattenuated correlation, .84). Burnout and depressive symptoms were similarly correlated with each of 3 stress-related factors, stressful life events, job adversity, and workplace support. In categorical analyses, 86% of the teachers identified as …


Psychoneuroimmunology: Enhancing Treatment Efficacy And Reducing Sexual Offender Recidivism In Court-Mandated Treatment, Cameron F. Zeidler 2016 Antioch University Santa Barbara

Psychoneuroimmunology: Enhancing Treatment Efficacy And Reducing Sexual Offender Recidivism In Court-Mandated Treatment, Cameron F. Zeidler

Antioch University Dissertations & Theses

Despite astronomical costs, state-funded sex offender treatment has a sole purpose of protecting communities at large. Designed to treat sexual psychopaths, costly state risk management programs are required to use traditional, outdated treatment models, which lack empirical support, lack published research, and lack curricula written at the seventh grade reading level. Psychoneuroimmunology (PNI) eagerly proves to be a new modality for Psychoeducation (PE) enhancing treatment efficacy and reducing offender recidivism in court-mandated treatment. The distinction in the present study is the difference between PE alone (control group) and PE with PNI (experimental group). Specifically, this study investigated the extent to …


Association Between Depression And Aggression In Rural Women, Laetitia Meyrueix, Gabriel Durham, Jasmine Miller, K. Bryant Smalley PhD, PsyD, Jacob C. Warren PhD 2015 University of New Mexico

Association Between Depression And Aggression In Rural Women, Laetitia Meyrueix, Gabriel Durham, Jasmine Miller, K. Bryant Smalley Phd, Psyd, Jacob C. Warren Phd

Journal of Health Disparities Research and Practice

Rural women represent approximately 20% of women living in the United States, yet research on the specific mental health needs of rural women is limited. Given the well-recognized gender-linked disparity in depression, its correlated symptoms in women still need much investigation. While emerging notions of depression in men embrace potential symptoms related to irritability and aggression, less research has focused on the potential role of aggression in depressed women. This connection may be particularly relevant for rural women who face unique mental health stressors in comparison to their urban counterparts. The purpose of this study was to examine if aggression …


The Hidden Epidemic: Mental Health Epidemiology In Post-Conflict Populations And Implications For Conflict Transformation Practices, Jennifer Sato 2015 SIT Graduate Institute

The Hidden Epidemic: Mental Health Epidemiology In Post-Conflict Populations And Implications For Conflict Transformation Practices, Jennifer Sato

Capstone Collection

This capstone explores the ramifications of unmitigated mental health illness in conflict populations, paying special attention to refugees and migrants. The intersection between conflict and mental health is explored and analyzed in order to highlight the implications of the findings and to make recommendations to both metal health and conflict transformation practitioners. This capstone depends predominately on secondary resources and personal interviews and is informed by my own practicum experience at a refugee health center. The need to improve mental health outcomes in order to pursue conflict transformation and peace building is a key focus and is supported by the …


The Effects Of Alpha Stimulation On Induced Anxiety, Nolan Thomas Hill 2015 Abilene Christian University

The Effects Of Alpha Stimulation On Induced Anxiety, Nolan Thomas Hill

Electronic Theses and Dissertations

Anxiety is defined as an emotional and physical reaction that prepares us to confront a feared stimulus. Among the many measureable changes induced by anxiety are changes in facial electromyography (EMG), heart rate (HR), and sweat gland activity (EDG). At a pathological level anxiety interferes with cognitive processes. Currently, when anxiety crosses into the pathological level, it is treated with a variety of therapies that share in their use of periods of exposure to anxiety-inducing stimuli. Several devices have been developed to alter brain activity by transcranial electrical stimulation (TCES). One such device, Alpha-Stim®, has been shown to …


Research Brief: "Military Service Absences And Family Members’ Mental Health: A Timeline Followback Assessment", Institute for Veterans and Military Families at Syracuse University 2015 Syracuse University

Research Brief: "Military Service Absences And Family Members’ Mental Health: A Timeline Followback Assessment", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This brief examines mental health correlating with a parent's absence during a military deployment. The findings show that adolescents were affected by a military parent being absent from significant events, and that they would benefit from programs that offer pre and post-deployment briefings. In the future, research should investigate how contact during military deployment affects the service member and their family.


Research Brief: "Receipt Of Employment Services Among Veterans Health Administration Users With Psychiatric Diagnoses", Institute for Veterans and Military Families at Syracuse University 2015 Syracuse University

Research Brief: "Receipt Of Employment Services Among Veterans Health Administration Users With Psychiatric Diagnoses", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This study found that about four percent (4.2%) of VHA users with psychiatric diagnoses accessed employment services in a given year. VHA patients with a psychiatric diagnosis of schizophrenia had higher odds of accessing employment services relative to VHA users with other psychiatric diagnoses, including PTSD, depression, and other anxiety disorders. In practice, veterans should be aware that receiving VHA employment services should not affect VA benefits and should discuss their medical and financial benefits with benefits advisors and other appropriate advisors. In policy, Policymakers could consider allocating funds to further study the efficacy and effectiveness of various employment services …


Research Brief: "Suicide Risk Among 1.3 Million Veterans Who Were On Active Duty During The Iraq And Afghanistan Wars", Institute for Veterans and Military Families at Syracuse University 2015 Syracuse University

Research Brief: "Suicide Risk Among 1.3 Million Veterans Who Were On Active Duty During The Iraq And Afghanistan Wars", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This brief is about a comparison between the post-service suicide risk of recent wartime veterans versus the suicide risk of the general population in the US. In policy and practice, veterans at risk for suicide should seek counseling, counselors should be aware of military service-specific stressors, and family members should support veterans through readjustment periods; the DoD and VA should continue offering medical screening and counseling services to recent veterans and veterans who were deployed. Suggestions for future research include examining the reasons for lower rates of suicide within certain military branches, determining the reasons for an excess suicide rate …


Research Brief: "Prevalence Of Suicidality Among Hispanic And African American Veterans Following Surgery", Institute for Veterans and Military Families at Syracuse University 2015 Syracuse University

Research Brief: "Prevalence Of Suicidality Among Hispanic And African American Veterans Following Surgery", Institute For Veterans And Military Families At Syracuse University

Institute for Veterans and Military Families

This brief is about the likelihood of suicidal behavior and ideation among African Americans and Hispanic Americans after surgery. In policy and practice, pain medications should be prescribed after major surgery, health professionals should evaluate for both physical and psychological suffering several months after surgery, and also provide more services to the patient if necessary; the VHA should expand its suicide prevention program and tailor interventions toward cultural subgroups. Suggestions for future research include looking at prescriber and patient characteristics when prescribing pain medication, looking at the differences in post-surgery coping by race, and relying on data from veterans about …


Apples And Oranges: An Argument For Psychopathy As A Formal Diagnosis, Katherine K. McMann 2015 University of Denver

Apples And Oranges: An Argument For Psychopathy As A Formal Diagnosis, Katherine K. Mcmann

Graduate School of Professional Psychology: Doctoral Papers and Masters Projects

When one thinks of the psychopath, an image of one of the notorious serial killers of the 1980s generally pops in their head- Ted Bundy, Jeffrey Dahmer, or the Green River Killer. While still rare, psychopaths encompass much more than just serial killers, and they have a unique presentation that lies outside the confines of any current diagnosis. Characteristics such as lack of empathy, impulsivity, grandiosity, and poor behavioral controls are included in various personality disorders. The Narcissist will show lack of empathy and grandiosity while the Borderline will have poor behavioral controls and impulsivity, for example. However, the construct …


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