Behavior and Behavior Mechanisms Commons^™

Getting Change-Space: A Grounded Theory Study Of Automated Ehealth Therapy, Marianne T. S. Holter, Ottar Ness, Ayna Johansen, Håvar Brendryen

The Qualitative Report

A promising tool for bettering people’s health is eHealth (or “mHealth”) programs: fully automated, web-based health interventions. However, we know surprisingly little about eHealth’s working mechanisms. One possible working mechanism is that program users benefit from a collaborative “relationship”—a “working alliance”—with the program. Although evidence support the existence of a person-to-program alliance it is unclear if and how it influences change. Therefore, we conducted a grounded theory study of how relating to an eHealth program for quitting smoking influenced the participants’ change processes. The ensuing model focuses on how participants got change-space—feeling free from social forcing and able to work …

Patterns Of Polysubstance Use Among Those With Tranquilizer Or Sedative Misuse: Predictors And Functional Consequences, Victoria R. Votaw

Psychology ETDs

The misuse of tranquilizer and sedative medications (i.e., use without a prescription or at higher doses/longer periods of time than prescribed) is associated with myriad negative sequalae, such as suicidal behaviors and increased risk of overdose. Yet, prescription tranquilizer and sedative misuse has been largely overlooked by the scientific community, clinicians, and policymakers. We addressed this gap in the literature by characterizing subgroups of individuals with tranquilizer or sedative misuse, based on their patterns of polysubstance use. The present study analyzed data from two samples of individuals with past-month tranquilizer or sedative misuse: respondents of a nationally-representative household survey (general …

Discriminative Stimulus Effects Of Putative Antipsychotic Drugs, Alex Lekander

All NMU Master's Theses

This study attempted to further explore the discriminative stimulus properties of antipsychotic drugs, by establishing the typical antipsychotic drug chlorpromazine, and the atypical antipsychotic drug clozapine as discriminative stimulus in two different groups of rats. The rats trained to discriminate chlorpromazine from vehicle failed to do so reliably, however nine of ten rats trained to discriminate 1.25 mg/kg clozapine from vehicle were able to acquire the discrimination in 19.1 sessions. The clozapine cue partially generalized (63.13% drug lever responding [SEM = ± 18.91]) to the antimalarial drug methylene blue at the 7.5 mg/kg dose, but not to the antimalarial quinacrine. …

Mouse Performance On A Novel Touchscreen Continuous Performance Task Is Dependent On Signaling In The Prelimbic Cortex, Tyler D. Dexter, Daniel Palmer, Amy C. Reichelt, Anita Taksokhan, Lisa M. Saksida, Tim J. Bussey

Western Research Forum

Attention is the cognitive processing that facilitates the ability to target and attend to relevant environmental stimuli, while filtering out irrelevant or distracting stimuli. Control over selective attention is theorized to be dependent on organized neural communication that stems from the medial prefrontal cortex (mPFC). To evaluate selective and sustained attention, mice were trained on the novel touchscreen rodent continuous performance task (rCPT), a task designed to emulate the human CPT. In the rodent version, images are continuously presented on a touchscreen, where mice have been trained to selectively respond to one image type while suppressing responses to all others. …

Pparg Signaling In The Nucleus Accumbens Regulates Mesolimbic Dopamine Activity, Tony Jung, Roger Hudson, Hanna Szkudlarek, Walter Rushlow, Steve Laviolette

Western Research Forum

Background: The mesolimbic dopamine system consists of dopamine neuron projections from the ventral tegmental area (VTA) to the nucleus accumbens (NAc). The NAc regulates VTA dopamine release through inhibitory GABA projections to the VTA. Hyperactive mesolimbic dopamine signaling is implicated in anxiety. Cannabidiol, a compound found in cannabis, demonstrates promising therapeutic potential for anxiety through the regulation of the mesolimbic dopamine system. Previous studies have revealed that cannabidiol infusions into the NAc decreases mesolimbic dopamine activity - potentially through the inhibitory GABA signaling to the VTA. However, the receptor mechanism in the NAc through which CBD produces its effects is …

An Integration-To-Bound Model Of Decision-Making That Accounts For The Spectral Properties Of Neural Data, Ramón Guevara Erra, Marco Arbotto, Aaron Schurger

Psychology Faculty Articles and Research

Integration-to-bound models are among the most widely used models of perceptual decision-making due to their simplicity and power in accounting for behavioral and neurophysiological data. They involve temporal integration over an input signal (“evidence”) plus Gaussian white noise. However, brain data shows that noise in the brain is long-term correlated, with a spectral density of the form 1/fα (with typically 1 < α < 2), also known as pink noise or ‘1/f’ noise. Surprisingly, the adequacy of the spectral properties of drift-diffusion models to electrophysiological data has received little attention in the literature. Here we propose a model of accumulation of evidence for decision-making that takes into consideration the spectral properties of brain signals. We develop a generalization of the leaky stochastic accumulator model using a Langevin equation whose non-linear noise term allows for varying levels of autocorrelation in the time course of the decision variable. We derive this equation directly from magnetoencephalographic data recorded while subjects performed a spontaneous movement initiation task. We then propose a nonlinear model of accumulation of evidence that accounts for the ‘1/f’ spectral properties of brain signals, and the observed variability in the power spectral properties of brain signals. Furthermore, our model outperforms the standard drift-diffusion model at approximating the empirical waiting time distribution.

Alterations In Cortical Activation Among Individuals With Chronic Ankle Instability During Single-Limb Postural Control, Adam B. Rosen, Jennifer M. Yentes, Melanie L. Mcgrath, Arthur C. Maerlender, Sara A. Myers, Mukul Mukherjee

Center for Brain, Biology, and Behavior: Faculty Publications

Context: Chronic ankle instability (CAI) is characterized by repetitive ankle sprains and perceived instability. Whereas the underlying cause of CAI is disputed, alterations in cortical motor functioning may contribute to the perceived dysfunction.

Objective: To assess differences in cortical activity during single-limb stance among control, coper, and CAI groups.

Design: Cross-sectional study.

Setting: Biomechanics laboratory.

Patients or Other Participants: A total of 31 individuals (10 men, 21 women; age = 22.3 ± 2.4 years, height = 169.6 ± 9.7 cm, mass = 70.6 ± 11.6 kg), who were classified into control (n = 13), coper (n = 7), and CAI …

Approach Bias For Erotic Stimuli In Heterosexual Male College Students Who Use Pornography, Shane Kraus, Skyler Sklenarik, Marc N. Potenza, Mateusz Gola, Ariel Kor, Robert S. Astur

Psychology Faculty Research

Background and Aims: Addicted individuals often demonstrate relatively automatic action tendencies in response to addiction-related stimuli, whereby they approach rather than avoid addictive stimuli. This study assessed whether an approach bias for erotic stimuli exists among heterosexual college-aged males who report using pornography. Methods: We tested 72 male undergraduate students using an approach–avoidance task employing erotic stimuli, during which participants were instructed to push or pull a joystick in response to image orientation. To simulate approach and avoidance movements, pulling the joystick enlarged the image and pushing shrunk the image. Frequency and severity of pornography use was assessed using a …

Dance/Movement Therapy As A Tool To Improve Social Skills In Children And Adolescents With Autism Spectrum Disorder: A Literature Review, Holly Berlandy

Expressive Therapies Capstone Theses

Abstract

Autism spectrum disorder is a neurodevelopmental disorder diagnosed by the presence of social communication and interaction deficits present in their day to day. The deficits present in this disorder appear within the first three years of life and lead to problems with connecting and interacting with other individuals including their own family members. As a result, children and adolescents with Autism spectrum disorder often experience negative self-image and lack the proper skills to interact with others. Autism spectrum disorder is becoming more commonly diagnosed and yet there remains a gap in interventions and treatment due to the individualized appearance …

Assessment Of Motor Function, Motor Learning, & Olivary Climbing Fiber Distribution Within Developmental Hyperserotonemia Rat Model For Autism Spectrum Disorder, Elizabeth Diane Holland

Graduate Theses/Dissertations

While Autism Spectrum Disorder (ASD) is defined by deficits in social communication, compromised motor function and motor learning have been increasingly reported. Motor deficits could compound social impairment through delayed language acquisition, reduced opportunity for social interaction, and affected nonverbal communication. One area of interest in the investigation of motor dysfunction is the cerebellum, where altered cerebellar structure and connectivity have been reported in those diagnosed with ASD. Morphological and functional changes in cerebellar circuitry could disrupt motor skill development and may be associated with developmental alterations of the serotonergic system. Elevated blood serotonin in perinatal development, developmental hyperserotonemia (DHS), …

It Is In The Cards: An Analysis Of Greeting Card Selection Through Identity And Personality, Emily Topilow

Honors Projects

In this exploratory study, personal and social identity were analyzed for their effect on how consumers choose greeting cards. Factors, including personality, relationships, and identity will be qualitatively analyzed to understand people’s buying habits. Certain factors, including gender, personality, relationships, type of card, and frequency of receiving and giving cards, will be qualitatively analyzed for frequency. The two theories analyzed were the Social Identity Theory (SIT) and the Identity Theory (IT).

525 college-aged students were surveyed to examine their purchasing habits of greeting cards. The results showed that the identity of the card giver and the identity of the card …

Inducing Incentive Sensitization Of Exercise Reinforcement Among Adults Who Do Not Regularly Exercise—A Randomized Controlled Trial, Kyle D. Flack, Kelsey Elise Ufholz, Luann Johnson, James N. Roemmich

Dietetics and Human Nutrition Faculty Publications

Background

Increasing exercise reinforcement, or decreasing sedentary reinforcement, may reduce sedentary activity and promote habitual exercise. Repeated exposures to a reinforcer may increase its reinforcing value (i.e., incentive sensitization). It is not yet known whether incentive sensitization occurs for exercise or factors associated with incentive sensitization for exercise reinforcement. The purpose was to determine whether exercise exposures increase exercise reinforcement relative to a sedentary alternative and whether this sensitization of exercise reinforcement would alter physical or sedentary behavior. This work also determined whether exercise dose, intensity, and preference and tolerance for exercise intensity were associated with incentive sensitization of exercise. …

Rationale, Design, And Baseline Characteristics Of Walkit Arizona: A Factorial Randomized Trial Testing Adaptive Goals And Financial Reinforcement To Increase Walking Across Higher And Lower Walkable Neighborhoods, Marc A. Adams, Jane Hurley, Christine Phillips, Michael Todd, Siddhartha Angadi, Vincent Berardi, Melbourne F. Hovell, Steven Hooker

Psychology Faculty Articles and Research

Little change over the decades has been seen in adults meeting moderate-to-vigorous physical activity (MVPA) guidelines. Numerous individual-level interventions to increase MVPA have been designed, mostly static interventions without consideration for neighborhood context. Recent technologies make adaptive interventions for MVPA feasible. Unlike static interventions, adaptive intervention components (e.g., goal setting) adjust frequently to an individual's performance. Such technologies also allow for more precise delivery of “smaller, sooner incentives” that may result in greater MVPA than “larger, later incentives”. Combined, these factors could enhance MVPA adoption. Additionally, a central tenet of ecological models is that MVPA is sensitive to neighborhood environment …

The Effects Of Adenosine Antagonists On Vigilant Attention In Sleep Restricted Rats, Morgan Crewe

Masters Theses, 2010-2019

The relation between chronic sleep restriction and performance on the Psychomotor Vigilance Task (PVT) have been well documented in the human literature, with chronic sleep restriction as little as 7 hours per night resulting in significant impairment in sustained attention performance measured via the PVT. Recently, an analogous version of the human PVT has been developed for use with rodent models (rPVT). Recent studies have measured the effects of sleep restriction on rPVT performance, citing similar results found in the human literature. However, few studies to date have directly examined the role of adenosine accumulation during sleep deprivation in producing …

Understanding The Help-Seeking Behaviors Of Student-Athletes: Effect Of A Multidisciplinary Healthcare Team And The Perception Of Barriers And Facilitators For Seeking Help, Lauren M. Sander

Masters Theses, 2010-2019

This study was aimed at identifying barriers and facilitators that influence help-seeking as well as the effect of implementing an integrated healthcare approach based on current recommendations. A total of 411 student-athletes from 18 intercollegiate teams at a mid-major Division I institution in the mid-Atlantic region completed a 12–item instrument comprised of ten quantitative items and two open-ended questions. The quantitative data was analyzed using SPSS software, and a constant comparative method was used to code responses from the open-ended questions. Findings suggested a prevalence of mental health challenges among student-athletes, especially overwhelming stress, struggles with time management, and anxiety. …

Posture Affects Affordance Perception Of Reachability In Virtual Reality, Hannah Masoner

Master's Theses

Tasks such as standing and reaching require differing levels of postural stability. Postural equilibrium is necessary to perceive the location of objects (Lee, Pacheco, & Newell, 2018). Visual perception of whether an object is within reach was investigated while standing upright. Participants viewed a 3D virtual reality (VR) environment with a stimulus object (red ball) placed at different egocentric distances. Participants made affordance judgements while in a standard stance condition as well as two separate active balance conditions (yoga tree pose, and toe-to-heel pose). Feedback on accuracy was not provided, and participants were not allowed to attempt to reach. Response …

A Sensory-Based Program To Enhance Occupational Performance For Dementia, Ivy Annahi Torres-Flores, Jacob Gantan, Heather Anne August, Naomi Grace Wong

Occupational Therapy | MSOT Capstone Projects

Dementia is a neurological disease, causing behavioral and cognitive symptoms, that progressively impairs an individual’s ability to engage in meaningful activities. Progressive deterioration associated with dementia impacts occupational performance and independence and quality of life. Sensory based interventions, such as drumming groups, have been hypothesized to be a non-pharmacological intervention for individuals with dementia. The purpose of this study was to analyze the effects of a sensory based intervention program, in this case participation in a drumming group, on functional engagement during self-feeding for individuals with dementia. Researchers gathered data over the course of two days using the Functional Behavior …

Measuring Neural Time Series Data In A Sensory Deprivation Tank, Jackson Gregory, Tian Lan, Uri Maoz, Amir Raz

Student Scholar Symposium Abstracts and Posters

We are interested in studying the neurological and physiological effects of the float pod, also known as REST therapy, or sensory deprivation tank. Float pods rely on the concept of depriving most senses (from sound and light to temperature and proprioception) in a pool filled with buoyant salt water at body temperature. While float pods are most commonly used in spa environments, we intend to look at the potential benefits of floating under the empirical lens. In this study, we aim to measure neural activity using electroencephalography (EEG). We intend to look at the different levels of relaxation and the …

The Effects Of Two Novel Anti-Inflammatory Compounds On Prepulse Inhibition And Neural Microglia Cell Activation In A Rodent Model Of Schizophrenia, Heath W. Shelton

Electronic Theses and Dissertations

Recent studies have shown elevated neuroinflammation in a large subset of individuals diagnosed with schizophrenia. A pro-inflammatory cytokine, tumor necrosis factor-alpha (TNFα), has been directly linked to this neuroinflammation. This study examined the effects of two TNFα modulators (PD2024 and PD340) produced by our collaborators at P2D Bioscience, Inc., to alleviate auditory sensorimotor gating deficits and reduce microglial cell activation present in the polyinosinic:polycytidylic (Poly I:C) rodent model of schizophrenia. Auditory sensorimotor gating was assessed using prepulse inhibition and microglial activation was examined and quantified using immunohistochemistry and confocal microscopy, respectively. Both PD2024 and PD340 alleviated auditory sensorimotor gating deficits …

Associations Of First Trimester Co-Use Of Tobacco And Cannabis With Prenatal Immune Response And Psychosocial Well-Being, Kristin Ashford, Amanda Fallin-Bennett, Andrea Mccubbin, Amanda T. Wiggins, Sheila Barnhart, Joshua A. Lile

Perinatal Research and Wellness Center Faculty Publications

PURPOSE: This study aims to describe the association of first trimester co-use of tobacco and cannabis with maternal immune response and psychosocial well-being, relative to tobacco use only.

METHODS: A preliminary midpoint analysis included 138 pregnant women with biologically verified tobacco use, 38 of whom (28%) also tested positive for recent cannabis use. Maternal perceived stress (Perceived Stress Scale), depressive symptoms (Edinburgh Postnatal Depression Scale), and serum immune markers (IL-1β, IL-2, IL-6, IL-8, IL-10, TNFα, CRP, MMP8), were collected, although cytokine data were only available for 122 women.

RESULTS: Participant average age was 29.1 years, approximately half had a high …