Behavior and Behavior Mechanisms Commons^™

Adaptation Of A Standard Extended-Release Naltrexone (Xr-Ntx) Protocol For Rural Re-Entering Offenders With Oud, Michele Staton, Hannah K. Knudsen, Sharon L. Walsh, Carrie B. Oser, Erika Pike, Michelle R. Lofwall

Behavioral Science Faculty Publications

BACKGROUND: Despite a growing body of empirical support for the effectiveness of extended-release naltrexone (XR-NTX) to reduce opioid relapse among people with opioid use disorder (OUD) transitioning from a correctional facility to the community, continuity of care following release remains challenging. This paper describes a research-based adaptation of a state's standard of care XR-NTX protocol using the ADAPT-ITT framework for delivery in a non-traditional, non-treatment, community criminal justice setting (P&P office), as well as the expansion of services by a local Federally Qualified Health Center (FQHC) provider who would, for the first time, be going to the jail and P&P …

Learning Without Contingencies Induces Higher Order Asynchrony In Brain Networks In Schizophrenia, Elizabeth L. Martin, Asadur Chowdury, Vaibhav Diwadkar, Sazid Hasan, Munajj Ul-Huq, Shahira Baajour, Dalal Khatib, Usha Rajan, Jeffrey Stanley

Medical Student Research Symposium

Schizophrenia (SCZ) is characterized by both cognitive and reward impairments. A recent study suggests that SCZ is associated with a loss of synchrony between learning and reward circuits (Robison et al., 2019) and higher levels of dis-organization of functional brain networks may underpin failures in learning that characterize SCZ (Hütt et al., 2014). Therefore, here we examined inter-group (HC ≠ SCZ) 4^th order differences in statistical regularity across a connectome of cognition and reward brain circuits. The analyses were conducted on fMRI time series data from a previous learning paradigm (Stanley et al., 2017) with periods of Encoding and …

Memory-Related Frontal Brainwaves Predict Transition To Mild Cognitive Impairment In Healthy Older Individuals Five Years Before Diagnosis, Yang Jiang, Juan Li, Frederick A. Schmitt, Gregory A. Jicha, Nancy B. Munro, Xiaopeng Zhao, Charles D. Smith, Richard J. Kryscio, Erin L. Abner

Behavioral Science Faculty Publications

BACKGROUND: Early prognosis of high-risk older adults for amnestic mild cognitive impairment (aMCI), using noninvasive and sensitive neuromarkers, is key for early prevention of Alzheimer's disease. We have developed individualized measures in electrophysiological brain signals during working memory that distinguish patients with aMCI from age-matched cognitively intact older individuals.

OBJECTIVE: Here we test longitudinally the prognosis of the baseline neuromarkers for aMCI risk. We hypothesized that the older individuals diagnosed with incident aMCI already have aMCI-like brain signatures years before diagnosis.

METHODS: Electroencephalogram (EEG) and memory performance were recorded during a working memory task at baseline. The individualized baseline neuromarkers, …

Resting Cerebral Oxygen Metabolism Exhibits Archetypal Network Features, Nicholas A. Hubbard, Monroe P. Turner, Kevin R. Sitek, Kathryn L. West, Jakub R. Kaczmarzyk, Lyndahl Himes, Binu P. Thomas, Hanzhang Lu, Bart Rypma

Center for Brain, Biology, and Behavior: Faculty Publications

Standard magnetic resonance imaging approaches offer high-resolution but indirect measures of neural activity, limiting understanding of the physiological processes associated with imaging findings. Here, we used calibrated functional magnetic resonance imaging during the resting state to recover low-frequency fluctuations of the cerebral metabolic rate of oxygen (CMRO2). We tested whether functional connections derived from these fluctuations exhibited organization properties similar to those established by previous standard functional and anatomical connectivity studies. Seventeen participants underwent 20 min of resting imaging during dual-echo, pseudocontinuous arterial spin labeling, and blood-oxygen-level dependent (BOLD) signal acquisition. Participants also underwent a 10 min normocapnic and hypercapnic …

Sex Differences And Psychological Stress: Responses To The Covid-19 Pandemic In China, Shiyan Yan, Rui Xu, Terry D. Stratton, Voyko Kavcic, Dan Luo, Fengsu Hou, Fengying Bi, Rong Jiao, Kangxing Song, Yang Jiang

Behavioral Science Faculty Publications

BACKGROUND: About 83,000 COVID-19 patients were confirmed in China up to May 2020. Amid the well-documented threats to physical health, the effects of this public health crisis - and the varied efforts to contain its spread - have altered individuals' "normal" daily functioning. These impacts on social, psychological, and emotional well-being remain relatively unexplored - in particular, the ways in which Chinese men and women experience and respond to potential behavioral stressors. Our study investigated sex differences in psychological stress, emotional reactions, and behavioral responses to COVID-19 and related threats among Chinese residents.

METHODS: In late February (2020), an anonymous …

Somatosensory Dysfunction Is Masked By Variable Cognitive Deficits Across Patients On The Alzheimer’S Disease Spectrum, Alex I. Wiesman, Victoria M. Mundorf, Chloe C. Casagrande, Sara L. Wolfson, Craig M. Johnson, Pamela E. May, Daniel L. Murman, Tony W. Wilson

Center for Brain, Biology, and Behavior: Faculty Publications

Background: Alzheimer’s disease (AD) is generally thought to spare primary sensory function; however, such interpretations have drawn from a literature that has rarely taken into account the variable cognitive declines seen in patients with AD. As these cognitive domains are now known to modulate cortical somato-sensory processing, it remains possible that abnormalities in somatosensory function in patients with AD have been suppressed by neuropsychological variability in previous research. Methods: In this study, we combine magnetoencephalographic (MEG) brain imaging during a paired-pulse somatosensory gating task with an extensive battery of neuropsychological tests to investigate the influence of cognitive variability on estimated …

Parenting Stress And Child Disruptive Behaviors: The Mediating Role Of Parental Negative Talk, David Roehm

Mahurin Honors College Capstone Experience/Thesis Projects

High parental stress and child disruptive behaviors tend to coexist. Furthermore, parental negative talk towards children cam impair child functioning later in life. In the present study, we sought to determine whether parental negative talk was a mediating variable between parenting stress and child disruptive behaviors. Fifty-two parent-child dyads from Eastern Kentucky participated in an analog Parent-Child Interaction Therapy (PCIT) behavioral observation and parents were given self-report measures for parenting stress and child disruptive behaviors.

Bivariate and multiple regression analyses were used to predict variance in child disruptive behaviors based on parenting stress with parental negative talk as a mediating …

Nurse Practitioners’ Knowledge And Perceptions Regarding Substance Use, Audrey Bailey, Paden Dawkins, Amber Hankins, Erin Mckinney

MSN Research Projects

Substance use disorder (SUD) is an illness impacting many people today and continues to not be truly understood, even by providers. To gain a greater understanding of this issue in relation to nurse practitioners, the researchers surveyed nurse practitioners in the Southeastern United States. The goal of the study was to identify knowledge and perceptions of nurse practitioners regarding substance use and misuse. Watson’s Theory of Caring was used to guide the study. The research questions that guided this study were 1. Do nurse practitioners have a bias toward patients with substance use disorder, and 2. Do nurse practitioners believe …

Readiness To Change In Rural Adults At High Risk For Diabetes, Katherine A. Wagner

Dissertations and Theses

Type II diabetes is one of the most devastating chronic diseases in the United States and is associated with decreased lifespan and serious comorbidities. While evidence-based prevention strategies of nutrition and physical activity exist, behavior change is an essential component. Researchers use readiness to change to predict clinical outcomes of chronic disease prevention programs, however, this has not been well studied in rural populations. The purpose of this research was to study the relationship between readiness to change and attrition rates and clinical outcomes among rural dwellers enrolled in a nutrition and physical activity intervention. Article one of this three-article …

Anxiety Explains Self-Differentiation: Implications For Bowenian Approaches To Marriage And Family Therapy, Reagan Thomas, John Shelley-Tremblay, Harvey Joanning

University Faculty and Staff Publications

This study examined the Bowenian construct of Self- Differentiation (SD), defined as the degree to which a person can think according to their personal beliefs while remaining emotionally connected to the family. This study examined the degree to which negative emotionality accounted for the relationship between SD and Relationship Satisfaction (RS). Emotional Cutoff (EC) emerged as the sole predictor of RS. When Trait Anxiety (TA) was entered into the model it mediated between EC and RS. We discuss the importance of treating anxiety of the individual in family therapy and that SD may best be understood when taking anxiety into …

Why Do You Wear A Mask? Children’S Conceptualizations Of Covid-19 And Contagion Avoidance Behaviors, Emily Hillman

Scripps Senior Theses

With the outbreak of the COVID-19 pandemic, a need has emerged for psychological research on children’s understanding of infectious disease transmission. However, little existing research examines the link between children’s cognitive reasoning about illness and their subsequent behaviors regarding its transmissibility. This study will examine children’s conceptualizations of contagious illnesses such as COVID-19 and their subsequent contagion avoidance. A mixed methods approach will be used to establish the content of children’s conceptualizations of contagion and level of causal reasoning related to illness transmission. Dyads will be constructed comprising 4-12-year-old children and their parents. It is expected that parental contagion avoidance …

Human Development, Portland State University. Human Development Teaching And Learning Group

PDXOpen: Open Educational Resources

This open textbook is designed for Human Development, a core Psychology course. This course provides a bird’s eye view of major milestones and developmental tasks during each age period, starting at conception and ending with old age.

In Patients With Mild To Moderate Alzheimer’S, Does Music Therapy Help To Decrease Mood Disturbances When Compared To Those Not Participating In Music Therapy?, Lauren Bauer

Capstone Showcase

Abstract:

Introduction: Affecting both memory and cognitive abilities, Alzheimer’s disease is a growing problem as the baby boomer population ages. Clinical trials for new medications fail or are slow going, researchers have sought alternatives to alleviate symptoms for patients of this disease. This paper will address the effect of music therapy on mood disturbance in patients with Alzheimer’s disease.

Method: A literature search was completed in November of 2019 using PubMed, EBSCO Search, ScienceDirect, and Google Scholar. Six articles were chosen based on relevance to the research question, study design, outcome, and results.

Results: Based on review, music …

The Effects Of Psychological Intervention On Pregnant Women With Elevated Cortisol Levels And Adverse Birth Events, Megan Mellon

Capstone Showcase

Elevated levels of stress, anxiety, and depression during pregnancy are thought to influence cortisol levels. Dysregulations in cortisol, as a byproduct of the hypothalamic-pituitary axis, have been associated with preterm birth and adverse birth outcomes. Studies have demonstrated poorer long-term effects of antenatal stress on child neurodevelopment, temperament, and cognition. Psychological interventions of cognitive behavioral therapy (CBT), mindfulness, and gratitude have shown to have a positive effect on psychological wellbeing across various populations. The purpose of this literature review was to analyze a collection of randomized-controlled trials to conclude if psychological interventions during pregnancy for women with elevated levels of …

The Association Of Menthol Cigarette Use With Any Mental Illness (Ami) And Serious Mental Illness (Smi) Among Us Smoekrs, Augustus White

Graduate Research Posters

ABSTRACT

Background: Mental illness affects 1-in-5 adults in the United States (US). Previously, those with mental illness have been shown to be 70% more likely to smoke cigarettes than the general population. However, little is known regarding whether the use of menthol cigarettes (one of only two available “characterizing flavors” of cigarettes) might impact the association between tobacco use and mental illness. Such information is critical in light of the disproportionately high rate of use of menthol cigarettes observed among African American smokers, as well as to inform recent legislative proposals that seek to ban the sale of menthol cigarettes. …

Harming The Help-Seeking: Necessity For Assessing Harmful And Biased Attitudes Toward Clients With Substance Use Disorder, Crystal D. Mcdowell, Crystal Dawn Mcdowell

Psychology Doctoral Specialization Projects

Numerous times, as a new clinician, I have witnessed the substance use disorder population referred to as not being dependable, dangerous, burnt out, and even hopeless. Often times I have heard mental health professionals make statements amongst themselves that the client could not be helped, referred to them as a “frequent flyer,” (meant to convey they frequently present for treatment, relapse, and return for treatment), and complain how tax dollars are being wasted to support the client. I felt empathy and a sense of hopelessness for these clients as they were seeking treatment in order to get help and yet …

Does A Brief Mindfulness Induction Change Delay Discounting In Individuals With High Levels Of Obsessive-Compulsive Symptoms?, Cierra B. Edwards

Graduate Theses, Dissertations, and Problem Reports (ETD)

Obsessive-compulsive disorder (OCD) is a mental illness characterized by obsessions and compulsions that cause significant distress and/or functional impairment. Delay discounting, the decline in value of a reward with the delay of its receipt, is linked to a range of maladaptive behaviors and mental disorders. Increased delay discounting is related to obsessive-compulsive disorder (OCD), reflecting that compulsive behaviors that aim to counteract obsessive thoughts are viewed as uncontrollable by the sufferer. We aimed to experimentally reduce delay discounting in individuals with high levels of obsessive-compulsive symptoms through a brief mindfulness induction. Eligible participants were randomly assigned to receive either a …

Effects Of Acute And Chronic Nicotine Administration On Choice Of Probabilistic Outcomes, Katya A. Nolder

Graduate Theses, Dissertations, and Problem Reports (ETD)

Risky choice can be operationally defined as the choice for a larger, uncertain reinforcer over a smaller, certain reinforcer. Research suggests smokers engage in more risky or maladaptive decisions when compared to nonsmokers. The relation between nicotine and risky choice could benefit from further investigation, since nicotine is the active substance of tobacco products that maintains tobacco addiction. Acute nicotine administration has shown to alter risky choice; however, since the everyday smoker uses nicotine repeatedly, more research on chronic administration is warranted and would allow for assessment of tolerance or sensitization of these effects. The present study investigated effects of …

Opioid System's Involvement In Ketamine's Antidepressant-Like Effects, Fan Zhang

Theses and Dissertations

Depression is one of the most debilitating disorders in the world. The currently available medications typically have a 2-4 week delay in their therapeutic effects and are ineffective for about 40% of patients. In 2000, a subanesthetic dose (0.5 mg/kg i.e.) of the dissociative anesthetic ketamine was reported to have both rapid and robust antidepressant effects in in treatment-resistant depressed patients. However, the mechanisms responsible for ketamine’s antidepressant effects remain unclear. In 2018, a clinical study reported that pretreatment with the nonselective opioid antagonist naltrexone attenuated the rapid antidepressant effect of ketamine in depressed patients. The current study investigated the …

Investigating Cannabinoid Type-1 Receptor (Cb1r) Positive Allosteric Modulators (Pams) In Mouse Models Of Overt Cannabimimetic Activity, Subjective Drug Effects, And Neuropathic Pain, Jayden Elmer

Theses and Dissertations

Chronic pain affects between 20 and 30 percent of the adult population in western countries and represents a wide array of specific etiologies (Berge, 2011). Neuropathic pain secondary to traumatic nerve injury, chemotherapeutic toxicity, or diseases (e.g., diabetes mellitus) is often refractory to conventional analgesics, with patients receiving less than 50% pain relief compared to placebo (Finnerup et al. 2010). The endocannabinoid system has shown potential as a therapeutic target for neuropathic pain wherein CB1 agonism via administration of exogenous agonists or pharmacological blockade of endocannabinoid catabolic enzymes exhibits efficacy in reversing allodynia in the chronic constriction injury (CCI) model …