Behavior and Behavior Mechanisms Commons^™

Higher Sexual Excitation Is Associated With An Increase In Sex-Linked Substance Use In Women With A History Of Unwanted Sexual Contact, Harper R. Jones, Tierney K. Lorenz

Center for Brain, Biology, and Behavior: Faculty Publications

Survivors of unwanted sexual contact have an increased likelihood of using substances in sexual situations, which puts them at heightened risk for intoxication-related harms. Separately, research has indicated that women may intentionally use substances in sexual situations to either enhance pleasure (i.e., increase sexual excitation) and/or reduce sexual anxiety or shame (i.e., reduce sexual inhibition), a phenomenon termed sex-linked substance use (SLSU). A predominant assumption in the literature is that women with unwanted sex histories are more likely to disengage during sex, suggesting greater inhibition-related SLSU; however, there is little prior research directly examining if women who have unwanted sex …

Pre–Post Intervention Exploring Cognitive Function And Relationships With Weight Loss, Intervention Adherence And Dropout, Amanda N. Szabo-Reed, Laura E. Martin, Cary R. Savage, Richard A. Washburn, Joseph E. Donnelley

Center for Brain, Biology, and Behavior: Faculty Publications

Objective: To evaluate the association between baseline cognitive function, intervention dropout, adherence and 3-month weight loss (WL) when controlling for confounding demographic variables.

Methods: 107 (Mage = 40.9 yrs.), BMI in the overweight and obese range (BMI = 35.6 kg/m2), men (N = 17) and women (N = 90) completed a 3-month WL intervention. Participants attended weekly behavioral sessions, comply with a reduced calorie diet, and complete 100 min of physical activity (PA)/wk. Cognitive function tasks at baseline included Flanker (attention), Stroop (executive control) and working memory, demographics, body weight and cardiovascular fitness were assessed at baseline. Session attendance, adherence …

Concussion-Related Disruptions To Hub Connectivity In The Default Mode Network Are Related To Symptoms And Cognition, Heather C. Bouchard, Kate L. Higgins, Grace Amadon, Julia M. Laing-Young, Arthur C. Maerlender, Seima Al-Momani, Maital Neta, Cary R. Savage, Douglas H. Schultz

Center for Brain, Biology, and Behavior: Faculty Publications

Concussions present with a myriad of symptomatic and cognitive concerns; however, the relationship between these functional disruptions and the underlying changes in the brain are not yet well understood. Hubs, or brain regions that are connected to many different functional networks, may be specifically disrupted after concussion. Given the implications in concussion research, we quantified hub disruption within the default mode network (DMN) and between the DMN and other brain networks. We collected resting-state functional magnetic resonance imaging data from collegiate student-athletes (n = 44) at three timepoints: baseline (prior to beginning their athletic season), acute post-injury (approximately 48 hours …

Manydogs Project: A Big Team Science Approach To Investigating Canine Behavior And Cognition, Daniela Alberghina, Emily E. Bray, Daphna Buchsbaum, Sarah- Elizabeth Byosiere, Julia Espinosa, Gitanjali E. Gnanadesikan, C.-N. Alexandrina Guran, Elizabeth Hare, Daniel J. Horschler, Ludwig Huber, Valerie A. Kuhlmeier, Evan L. Maclean, Madeline H. Pelgrim, Bryan Perez, Dana Ravid-Schurr, Liza Rothkoff, Courtney L. Sexton, Zachary A. Silver, Jeffrey R. Stevens

Center for Brain, Biology, and Behavior: Faculty Publications

Dogs have a special place in human history as the first domesticated species and play important roles in many cultures around the world. However, their role in scientific studies has been relatively recent. With a few notable exceptions (e.g., Darwin, Pavlov, Scott, and Fuller), domestic dogs were not commonly the subject of rigorous scientific investigation of behavior until the late 1990s. Although the number of canine science studies has increased dramatically over the last 20 years, most research groups are limited in the inferences they can draw because of the relatively small sample sizes used, along with the exceptional diversity …

Sedative Hypnotic Medications: Effect On Negative Cognition And Insomnia, Austin L. Larsen

Theses and Graduate Projects

The pursuit of healthy sleep in the United States often involves the use of prescription medications that were never intended for long-term treatment of insomnia. The use of medication to address sleep difficulty has multiple sources, including the medical system and a consumer driven economy within the United States. Behavioral interventions for insomnia have been increasing in availability and effectiveness over time, but medication use continues to be a first-line treatment for sleep problems. The focus of the current paper is the exploration of relationships between sedative use, sleep difficulties, and negative cognition in a sample of 104 adult participants …

Unique Posttraumatic Growth Expression Among Homeless Males Currently Enrolled In Chemical Dependency Treatment, Travis T. Mord

Theses and Graduate Projects

Posttraumatic growth (PTG) has gained considerable research and clinical attention for the past three decades. While the impact of PTG has been well-researched in relation to trauma exposure, medical ailments, or mood related conditions, there are still a number of mental health conditions requiring further analysis. The current study examined the relationship between PTG and key substance use significance indicators, including diagnostic severity of the use disorder and number of previous substance use treatment attempts, among a sample (N = 136) of adult men who were enrolled in a mental illness/chemical dependency (MICD) intensive outpatient program (IOP). This study also …

Cannabinoid Poisoning-Related Emergency Department Visits And Inpatient Hospitalizations In Kentucky, 2017 To 2019, Stevie C. Britch, Sharon L. Walsh, Rachel Vickers-Smith, Shanna Babalonis, Svetla Slavova

Center on Drug and Alcohol Research Faculty Publications

Background and objectives: Cannabis is the most used federally illicit substance. Due to widespread medicinal use and state-level legalization, public perceptions of cannabis have shifted toward the assumption that cannabis is safe. However, cannabinoids can cause adverse medical complications that may lead people to seek treatment. This study characterized cannabinoid poisoning-related medical encounters, poisoning involving cannabinoids and other psychoactive substances, and cannabinoid poisoning-related cardiac complications. Methods: Administrative billing data for emergency department visits and inpatient hospitalizations in acute care facilities with a discharge date from January 1, 2017 to December 31, 2019 were used to characterize cannabinoid poisoning events in …

Evaluating The Acute Effect Of Vaping On Food Intake, Gabrielle Maldonado

Theses and Dissertations

Background: Weight control is a common motive for continued cigarette smoking, and weight concerns pose a barrier to quitting. These effects are driven in part by nicotine’s ability to reduce overall appetite and ultimately body weight. Electronic nicotine delivery systems (ENDS) have been marketed and used for weight control, suggesting that the use of these products potentially may share similar effects as well as barriers to quitting as observed for cigarette smoking. However, little to no controlled clinical lab evidence exists supporting ENDS use for weight control. The present study tested the influence of an ENDS on acute eating behavior …

Behavioral Markers And Endophenotypes Underlying Individual Differences In Ethanol Use, Haily R. Knapp

Honors Theses and Capstones

The main concern of this study is to evaluate the neurobiology of ethanol self-administration and cue-induced reinstatement in rats and its implications for Alcohol Use Disorder (AUD) prevention and treatment. The purpose of this study is to use a pre-clinical model of ethanol use to understand the individual effects at the neurobiological level. The study utilized economic demand and negative consequence testing to evaluate the rats' motivation to consume ethanol and their ability to relapse after periods of abstinence. The results showed individual and sex differences in ethanol consumption, with rats who placed a higher value on ethanol being more …

Developing Ecologically Valid Clinical Tools For Persons With Tbi: Understanding The Role And Impact Of Distractions, Deanna Pinnow

Theses and Dissertations--Rehabilitation Sciences

There is a critical need for the development of ecologically valid clinical tools to assess real-life cognitive functioning in persons impacted by traumatic brain injury (TBI). Chronic cognitive impairments that are exacerbated by distractions are one of the core factors contributing to poor home and community re-integration post injury. Simulation-based digital platforms (i.e., virtual reality, augmented reality, and mixed reality) have become potential solutions for eliciting real-world cognitive performance in clinical settings. Yet, there is a paucity of research investigating the role and impact of distractions on cognition. As a result, there is no clear framework of measuring distractions to …

Neurobiology Of Ptsd In Adults And Children: The Impact Of Stress-Induced Brain Abnormalities Across The Lifespan, Catherine Clover

Undergraduate Honors Theses

In the scholarly community, there is disagreement about the effects of PTSD or chronic stress on the brain of adults and children. Though PTSD or chronic stress are known to negatively affect neurobiological structures, specifically due to prolonged glucocorticoid excess, volumetric discrepancies between traumatized and control groups are not unanimously confirmed. This review sought to address the common understandings in academia of the effects of PTSD on the brains of adults and children. Literature on this topic indicated that, in adults, the hippocampus, cingulate gyrus, and prefrontal cortex bilaterally appeared to decrease in gray matter volume and the corpus callosum …

Sensory Marketing For Consumer Wellbeing, Josh Lundberg

Theses and Dissertations--Marketing and Supply Chain

Chapter 1. Many consumer decisions – from trying a new brand to trying a new recipe – involve some risk. However, although consumers’ appetite for risk has received over fifty years of investigation, the impact of situational variables (e.g., atmospherics) on consumer decision making involving risk remains relatively unexplored. To address this gap, the current work examines the influence of temperature, a ubiquitous situational influence, on consumers’ inclination toward risk. Across four studies, we find evidence for a positive relationship between temperature and risk taking, using multiple manipulations of temperature and measurements of risk. Evidence suggests that this effect is …

The Influence Of Early Childhood Parental Feeding Behaviors On Self-Regulation & Food Decision-Making In Young Adults, Natasha Singareddy

CMC Senior Theses

This study used data from a diverse set of undergraduates from the Claremont Colleges to examine the relationship between cognitive control (impulsivity and response inhibition) and self-regulatory ability as an indicator of sustained early childhood parental feeding behaviors in adulthood. In addition, the current study explored if early childhood parental feeding behaviors predicted food decision-making in adulthood as a result of perceived taste and nutritional value of food items. It was hypothesized that heightened impulsivity and impaired response inhibition as measures of cognitive control would correlate to poorer self-regulation, in turn reflecting a particular mode of early childhood parental feeding …

Cumulative Risk For Children’S Behavior Problems And Child Abuse Potential Among Mothers Receiving Substance Use Treatment: The Unique Role Of Parenting Stress, Stephanie Gusler, Angela Moreland

Psychiatry Faculty Publications

There is a high prevalence of children whose parents suffer with a substance use disorder (SUD), which is associated with negative outcomes for children such as behavior problems and parents’ child abuse potential. To understand negative consequences for children, it is important to consider a cumulative risk model, examining the impact of multiple co-occurring risks, as well as examine unique singular risk factors, such as parenting stress, which may have a direct effect on outcomes as well as mediate an association between cumulative risk and outcomes. Data came from 99 mothers with SUD, engaged in a substance treatment program. Results …

Cannabidiol And Delta-9-Tetrahydrocannabinol Interactions In Male And Female Rats With Persistent Inflammatory Pain, Stevie C. Britch, Rebecca M. Craft

Behavioral Science Faculty Publications

Cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC), 2 of the primary constituents of cannabis, are used by some individuals to self-treat chronic pain. It is unclear whether the painrelieving effects of CBD alone and in combination with THC are consistent across genders and among types of pain. The present study compared the effects of CBD and THC given alone and in combination in male and female rats with Complete Freund’s adjuvant-induced inflammatory pain. After induction of hindpaw inflammation, vehicle, CBD (0.05−2.5 mg/kg), THC (0.05−2.0 mg/kg), or a CBD: THC combination (3:1, 1:1, or 1:3 dose ratio) was administered i.p. twice daily for …

The Endowment Effect And Temporal Discounting Of Drug And Non-Drug Commodities, Sean D. Regnier, Mark J. Rzeszutek, Justin C. Strickland, Thomas Shellenberg, William W. Stoops

Behavioral Science Faculty Publications

Objectives: Despite a rich history of behavioral economic research on substance use there remains a need for further exploration of behavioral mechanisms that may underlie the etiology or persistence of substance use disorder. The purpose of this study was to measure the association between delay discounting and the endowment effect in people who smoke cigarettes, use cocaine, and controls, using online crowdsourcing. Methods: Participants were categorized to a cocaine group (n = 36), cigarette group (n = 48), or control group (n = 47) based on recent reported drug use. Based on group, participants completed up to three delay discounting …

The Moderating Effect Of Physical Activity On The Relationship Between Bullying And Mental Health Among Sexual And Gender Minority Youth, Sally J. Kirklewski, Ryan J. Watson, Carolyn Lauckner

Behavioral Science Faculty Publications

Background: Sexual and gender minority youth frequently experience bullying, which often contributes to higher depressive symptoms and lower self-esteem. Given that physical activity (PA) can mitigate depressive symptoms and improve self-esteem, we examined the moderating effect of PA on the relationship between bullying and mental health among sexual and gender minority youth.

Methods: Data from the Lesbian, Gay, Bisexual, Transgender, and Queer National Teen Survey (n = 9890) were analyzed. Hierarchical regression analyses examined the influence of history and frequency of being bullied, PA, and the interaction of these variables on depressive symptoms and self-esteem. Simple slopes analyses were used …

Psychopathy And Insight Within An Incarcerated Population, Courtney Steinorth

Graduate Theses/Dissertations

The clinical construct of psychopathy has been researched extensively relative to incarceration. Cognitive insight has shown to be related to prognosis and treatment outcomes with severe psychopathologies. There has been, however, limited research on both psychopathy and cognitive insight in relation to incarceration. The purpose of the present study was to examine the moderation of cognitive insight levels on rates of incarceration (the number of times someone has been incarcerated in a government detention facility) based on their level of self-reported psychopathic traits. A brief demographic questionnaire, the Beck Cognitive Insight Scale, and the Levenson Self-Report Psychopathy Scale were administered …

Effects Of Combined Ethanol And Nicotine Administration On Delay Discounting In Male And Female Sprague-Dawley Rats, Rebecca Lillian Chalme

Graduate Theses, Dissertations, and Problem Reports (ETD)

Ethanol (EtOH) and nicotine (NIC) are among the most commonly used and co-used drugs in the world. Co-use occurs in people who use one or both drugs chronically, but also in people who only consume one or both drugs acutely, often in a “bingeing and chipping” pattern. Given that each drug on its own has previously been shown to affect impulsive choice in delay-discounting procedures, with some indication that drug effects could vary by sex, the purpose of the present experiments was to investigate effects of combined EtOH and NIC at a range of dose combinations on delay discounting in …

Effects Of Ethanol And Nicotine Co-Administration On Risky Choice In Rats, Erin E. Wylie

Graduate Theses, Dissertations, and Problem Reports (ETD)

Individuals often engage in the comorbid use of alcohol (ethanol) and nicotine, leading to further-escalated health consequences than the use of either drug in isolation. Given the poor health outcomes resulting from the combined administration of ethanol and nicotine, some of which may be due to increased risky choice, more basic research is needed to better characterize drug/dose interactions on risky choice. Probability-discounting procedures involve a series of discrete choices between a smaller, certain reinforcer (i.e., a safer choice) and a larger, increasingly uncertain reinforcer (i.e., a riskier choice). Probability-discounting procedures allow for the assessment of …