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Structural Foundations Of Potassium Selectivity In Channelrhodopsins, Sukyeong Lee, Sang Bum Lee, Nuri Sung, Wendy W Xu, Changsoo Chang, Hyun-Eui Kim, Andre Catic, Francis T F Tsai 2023 The Texas Medical Center Library

Structural Foundations Of Potassium Selectivity In Channelrhodopsins, Sukyeong Lee, Sang Bum Lee, Nuri Sung, Wendy W Xu, Changsoo Chang, Hyun-Eui Kim, Andre Catic, Francis T F Tsai

Faculty, Staff and Student Publications

Mitochondria are critical to cellular and organismal health. To prevent damage, mitochondria have evolved protein quality control machines to survey and maintain the mitochondrial proteome. SKD3, also known as CLPB, is a ring-forming, ATP-fueled protein disaggregase essential for preserving mitochondrial integrity and structure. SKD3 deficiency causes 3-methylglutaconic aciduria type VII (MGCA7) and early death in infants, while mutations in the ATPase domain impair protein disaggregation with the observed loss-of-function correlating with disease severity. How mutations in the non-catalytic N-domain cause disease is unknown. Here, we show that the disease-associated N-domain mutation, Y272C, forms an intramolecular disulfide bond with Cys267 and …


Enhanced Discharge Preparation To Decrease Discharge Delays: A Quality Improvement Project, Angela Graham 2023 Bellarmine University

Enhanced Discharge Preparation To Decrease Discharge Delays: A Quality Improvement Project, Angela Graham

Graduate Theses, Dissertations, and Capstones

Increased length of stay (LOS) is a focus in hospitals as it has implications for decreased quality of care, increased cost of care, and results in care delays for other patients (Rojas-Garcia et al., 2018). LOS is a measure of a hospital’s efficiency and throughput, which is the process of admitting, treating, and discharging patients. Micallef et al. (2020) found a longer LOS can occur from having extra days due to inefficiency in delivering care or from delays in discharge once the patient no longer needs acute care. The longer a patient stays in the hospital, the greater the risk …


The Importance Of Educating Adolescent Mothers In The Postpartum Period, Sydney Price, Madelyn Travis, Reagan Schwable 2023 Murray State University

The Importance Of Educating Adolescent Mothers In The Postpartum Period, Sydney Price, Madelyn Travis, Reagan Schwable

Scholars Week

Due to the lack of policy or procedure for individualized education for adolescent mothers, we concluded that a educational checklist in the charting system would be the most effective way to properly educate young mothers during this confusing stage in their life. Specific education helps to improve perceived quality of care, safety/wellbeing in the young mother and newborn, and reducing the risks of complications such as postpartum depression or issues with pregnancy later on. In summary, ensuring that teenage mothers are fully educated before discharge will provide for better mother and baby outcomes.


Sterile Tubing Changes To Prevent Clabsis In The Nicu, Rachel Janson, Megan Meyer 2023 CentraCare Heatlh

Sterile Tubing Changes To Prevent Clabsis In The Nicu, Rachel Janson, Megan Meyer

Nursing Posters

Purpose Statement:

NICU patients have a decreased risk of CLABSI infections when two-person sterile central line changes are implemented into central line maintenance bundles compared to bundles that only use one-person clean line change techniques.

Background:

Neonates admitted to the neonatal care intensive care unit (NICU) often require the placement of central lines for the administration of medications, fluids, parental nutrition, and hemodynamic monitoring. Despite their many advantages, central lines can lead to serious infections, known as cental line associated bloodstream infections (CLABSI). These infections are not related to an infection from another site and develop within forty-eight hours of …


The Lived Experiences Of Icu, Med-Surg, And Er Nurses In The United States Attempting To Breastfeed During The Covid-19 Pandemic, Amy Seay 2023 The University of Southern Mississippi

The Lived Experiences Of Icu, Med-Surg, And Er Nurses In The United States Attempting To Breastfeed During The Covid-19 Pandemic, Amy Seay

Dissertations

Breastfeeding is important to promote the health of both mothers and babies (Centers for Disease Control and Prevention [CDC], 2021). Many mothers experience workplace barriers and stress which negatively impact breastfeeding duration (McCardel & Padilla, 2020; Nagel et al., 2022). However, a gap in the literature exists surrounding specific barriers and the impact of stress on U.S. nurses who breastfeed. Specifically, workplace challenges and stress among nurses resulting from the COVID-19 pandemic lack exploration.

This interpretive phenomenological study explored the lived experiences of ICU, Med-Surg, and ER nurses who attempted to breastfeed during the COVID-19 pandemic. Roy’s adaptation model was …


Implementing Team Birth To Improve Patient Satisfaction On An Ldrp (Team Birthsingleroom ) Unit, Deanna Higgins, Alyson WIllard, Teresa Rangel 2023 Providence

Implementing Team Birth To Improve Patient Satisfaction On An Ldrp (Team Birthsingleroom ) Unit, Deanna Higgins, Alyson Willard, Teresa Rangel

Articles, Abstracts, and Reports

No abstract provided.


Child Abuse From A Nursing Perspective: Assessment And Implications, Ashtyn Spring 2023 Liberty University

Child Abuse From A Nursing Perspective: Assessment And Implications, Ashtyn Spring

Senior Honors Theses

Nurses experience the relationship dynamics between pediatric patients and their families firsthand. Being informed by the goals of holistic care, nurses should be assessing for unhealthy dynamics among pediatric patients and their caregivers so they can respond appropriately when a potential for abuse is present. Healthcare workers have the duty to provide safety and healing to their patients. Through the unique contact nurses have with patients, their training for accurate assessment skills, and their responsibility as healthcare workers, nurses are placed with the opportunity to help children out of abusive situations. Prompt identification of the potential for abuse can prevent …


Nurses' Preparedness For Disaster Response In Rural And Urban Primary Healthcare Settings In Tanzania, Kahabi Isangula, Mary Lyimo, Yudas Ndungile, Elisha Robert 2023 Aga Khan University

Nurses' Preparedness For Disaster Response In Rural And Urban Primary Healthcare Settings In Tanzania, Kahabi Isangula, Mary Lyimo, Yudas Ndungile, Elisha Robert

School of Nursing & Midwifery, East Africa

Introduction: Nurses are often on the frontline of disaster management, providing care to patients with emerging physical, mental, and emotional turbulence, and acting as educators for health promotion and disaster prevention in both rural and urban contexts. However, the literature suggests that nurses are inadequately prepared for disaster response. This study examined preparedness for disaster response among nurses in rural and urban primary healthcare settings in Tanzania.

Methods: This qualitative descriptive study involved purposefully selected qualified nurses and nurse administrators working in rural (n=20) and urban (n=11) primary healthcare facilities in Tanzania. Telephone-based interviews were conducted to gather …


Kangaroo Care Education For Low Socioeconomic Status Families In The Neonatal Care Unit, Joara Peterson 2023 Dominican University of California

Kangaroo Care Education For Low Socioeconomic Status Families In The Neonatal Care Unit, Joara Peterson

Nursing | Student Research Posters

The early contact between mother and baby is known as skin-to-skin, also referred to as “kangaroo care” (KC). It involves placing the baby on the mother’s chest as soon as it is appropriate (Thompson, 1979). This interaction was primarily for bonding but many researchers have discovered additional benefits. There is significant correlation between kangaroo care and weight gain (especially for low birth weight infants), as well as body temperature and heart rate regulation, which reduces the risk of medical complications. It also decreases levels of stress in mothers and babies by lowering the release of cortisol hormone (Mohammadi et al. …


The Positive Effects Of Delayed Immersion Bathing For Newborns, Aubrey Stuart 2023 Murray State University

The Positive Effects Of Delayed Immersion Bathing For Newborns, Aubrey Stuart

Scholars Week

Problem: Newborn infants were once bathed only 2-4 hours after birth. The rate at which newborns experienced hypothermia, hypoglycemia, and a difficulty with exclusive breastfeeding was once much higher than it is today.

Methods: This project was a meta-analysis of multiple clinical trials regarding delayed infant bathing. Three main studies that implemented a 24 hour or later bathing program were chosen and reviewed to assess for trends in hypothermia, hypoglycemia, and the exclusive breastfeeding rates of newborns.

Results: In each study reviewed, the rates of hypoglycemia and hypothermia decreased while the rates of exclusive breastfeeding increased.

Implications: By delaying newborn …


Differences In Birth Weight Between Immigrants' And Natives' Children In Europe And Australia: A Lifecycle Comparative Observational Cohort Study, Sandra Florian, Mathieu Ichou, Lidia Panico, Stéphanie Pinel-Jacquemin, Tanja G. M. Vrijkotte, Margreet W. Harskamp-Van Ginkel, Rae-Chi Huang, Jennie Carson, Loreto Santa Marina Rodriguez, Mikel Subiza-Pérez, Martine Vrijheid, Sílvia Fernández-Barrés, Tiffany C. Yang, John Wright, Eva Corpeleijn, Marloes Cardol, Elena Isaevska, Chiara Moccia, Marjolein N. Kooijman, Ellis Voerman, Vincent Jaddoe, Marieke Welten, Elena Spada, Marisa Rebagliato, Andrea Beneito, Luca Ronfani, Marie-Aline Charles 2023 Edith Cowan University

Differences In Birth Weight Between Immigrants' And Natives' Children In Europe And Australia: A Lifecycle Comparative Observational Cohort Study, Sandra Florian, Mathieu Ichou, Lidia Panico, Stéphanie Pinel-Jacquemin, Tanja G. M. Vrijkotte, Margreet W. Harskamp-Van Ginkel, Rae-Chi Huang, Jennie Carson, Loreto Santa Marina Rodriguez, Mikel Subiza-Pérez, Martine Vrijheid, Sílvia Fernández-Barrés, Tiffany C. Yang, John Wright, Eva Corpeleijn, Marloes Cardol, Elena Isaevska, Chiara Moccia, Marjolein N. Kooijman, Ellis Voerman, Vincent Jaddoe, Marieke Welten, Elena Spada, Marisa Rebagliato, Andrea Beneito, Luca Ronfani, Marie-Aline Charles

Research outputs 2022 to 2026

Objective:

Research on adults has identified an immigrant health advantage, known as the 'immigrant health paradox', by which migrants exhibit better health outcomes than natives. Is this health advantage transferred from parents to children in the form of higher birth weight relative to children of natives?

Setting:

Western Europe and Australia.

Participants:

We use data from nine birth cohorts participating in the LifeCycle Project, including five studies with large samples of immigrants' children: Etude Longitudinale Française depuis l'Enfance - France (N=12 494), the Raine Study - Australia (N=2283), Born in Bradford - UK (N=4132), Amsterdam Born Children and their Development …


Effect Of Antenatal Milk Expression Education On Lactation Outcomes In Birthing People With Pre-Pregnancy Body Mass Index ≥ 25: Protocol For A Randomized, Controlled Trial, Jill R. Demirci, Melissa Glasser, Debra L. Bogen, Susan M. Sereika, Dianxu Ren, Kristin Ray, Lisa M. Bodnar, Therese A. O'Sullivan, Katherine Himes 2023 Edith Cowan University

Effect Of Antenatal Milk Expression Education On Lactation Outcomes In Birthing People With Pre-Pregnancy Body Mass Index ≥ 25: Protocol For A Randomized, Controlled Trial, Jill R. Demirci, Melissa Glasser, Debra L. Bogen, Susan M. Sereika, Dianxu Ren, Kristin Ray, Lisa M. Bodnar, Therese A. O'Sullivan, Katherine Himes

Research outputs 2022 to 2026

Background: Birthing people with pre-pregnancy body mass indices (BMIs) ≥ 25 kg/m2, particularly those without prior breastfeeding experience, are at increased risk for suboptimal lactation outcomes. Antenatal milk expression (AME) may be one way to counteract the negative effects of early infant formula supplementation common in this population. Methods: This ongoing, randomized controlled trial in the United States evaluates the efficacy of a telelactation-delivered AME education intervention versus an attention control condition on lactation outcomes to 1 year postpartum among 280 nulliparous-to-primiparous, non-diabetic birthing people with pre-pregnancy BMI ≥ 25 kg/m2. The assigned study treatment is delivered via four weekly …


A National, Electronic Health Record-Based Study Of Perinatal Hemorrhagic And Ischemic Stroke, Stuart Fraser, Samantha M Levy, Yashar Talebi, Sean I Savitz, Alicia Zha, Gen Zhu, Hulin Wu 2023 The Texas Medical Center Library

A National, Electronic Health Record-Based Study Of Perinatal Hemorrhagic And Ischemic Stroke, Stuart Fraser, Samantha M Levy, Yashar Talebi, Sean I Savitz, Alicia Zha, Gen Zhu, Hulin Wu

Faculty, Staff and Student Publications

BACKGROUND: Perinatal stroke occurs in approximately 1 in 1100 live births. Large electronic health record (EHR) data can provide information on exposures associated with perinatal stroke in a larger number of patients than is achievable through traditional clinical studies. The objective of this study is to assess prevalence and odds ratios of known and theorized comorbidities with perinatal ischemic and hemorrhagic stroke.

METHODS: The data for patients aged 0-28 days with a diagnosis of either ischemic or hemorrhagic stroke were extracted from the Cerner Health Facts Electronic Medical Record (EMR) database. Incidence of birth demographics and perinatal complications were recorded. …


Improve Exclusive Breastfeeding Rates Through Early Breastfeeding Initiation, Camille Chua, Beverly Holland 2023 Providence

Improve Exclusive Breastfeeding Rates Through Early Breastfeeding Initiation, Camille Chua, Beverly Holland

Providence Nursing Research Conference 2023 – Present

No abstract provided.


Effect Of Mindfulness Training On Nicu Nurses’ Professional Quality Of Life, Susan Egami, Martha Highfield, Sherri Mendelson 2023 Providence

Effect Of Mindfulness Training On Nicu Nurses’ Professional Quality Of Life, Susan Egami, Martha Highfield, Sherri Mendelson

Providence Nursing Research Conference 2023 – Present

No abstract provided.


Factors Influencing Instrumental Birth Rates: An Evidence Based Project, Douglas Nanu, Gabriel Alemayehu, Chase Eby, Teresa Rangel 2023 Providence

Factors Influencing Instrumental Birth Rates: An Evidence Based Project, Douglas Nanu, Gabriel Alemayehu, Chase Eby, Teresa Rangel

Providence Nursing Research Conference 2023 – Present

No abstract provided.


Improving Nursing Education Curriculum As A Tool For Strengthening The Nurse–Client Relationships In Maternal And Child Healthcare: Insights From A Human-Centered Design Study In Rural Tanzania, Kahabi Isangula, Eunice Pallangyo, Eunice Ndirangu 2023 Aga Khan University

Improving Nursing Education Curriculum As A Tool For Strengthening The Nurse–Client Relationships In Maternal And Child Healthcare: Insights From A Human-Centered Design Study In Rural Tanzania, Kahabi Isangula, Eunice Pallangyo, Eunice Ndirangu

School of Nursing & Midwifery, East Africa

Background. There are growing evidence of poor nurse–client relationships in maternal and child health (MCH). The nursing curriculum forms an important entry point for strengthening such relationships, consequently improving client satisfaction with nurses' competencies, confidence in the formal healthcare system, healthcare-seeking practices, continuity with care, and MCH outcomes.

Objective. MCH nurses and clients were invited to design an intervention package (prototype) to improve nurse–client relationships using a human-centered design (HCD) approach.

Methods. A multi-step HCD approach was employed to first examine the contributors of poor nurse–client relationships using nine focus group discussions with nurses and clients and 12 key informant …


Caesarean Section For Placenta Previa: A Retrospective Cohort Study Of Anaesthesia Techniques, Samina Ismail, Saima Rashid 2023 Aga Khan University

Caesarean Section For Placenta Previa: A Retrospective Cohort Study Of Anaesthesia Techniques, Samina Ismail, Saima Rashid

Department of Anaesthesia

Objective: Placenta previa is associated with maternal and neonatal morbidity and mortality. This study aims to add to the limited literature from the developing world on the association of different anaesthetic techniques with blood loss, the need for blood transfusion, and maternal/ neonatal outcomes among women undergoing caesarean section with placenta previa.
Methods: This retrospective study was conducted at Aga University Hospital, Karachi, Pakistan. The patient population included parturients undergoing caesarean section for placenta previa from January 1, 2006, through December 31, 2019.
Results: Out of 276 consecutive cases of placenta previa progressing to caesarean section during the study period, …


Pediatric Obesity In Primary Care, Lynne C. Liggins 2023 Abilene Christian University

Pediatric Obesity In Primary Care, Lynne C. Liggins

Electronic Theses and Dissertations

The purpose of this evidence-based quantitative quasi-experimental research was to compare if providing the parents with information on the health risk associated with childhood obesity would cause the parents to make healthier food choices and encourage their children to be involved in a full hour of physical activity a day. Participants included parents and pediatric and adolescent children 5 to 18 years of age at a solo practice primary care office in a large city in Southern, California, which specializes in treating pediatric and adolescent patients. A pre- and postquantitative intervention design were used and analyzed using the paired t …


Substrate Electronics Dominate The Rate Of Reductive Dehalogenation Promoted By The Flavin-Dependent Iodotyrosine Deiodinase, Jeffrey M Carlson, Ayzsa Tannis, Kate R Woodworth, Megan R Reynolds, Neha Shinde, Breanne Anderson, Keivon Hobeheidar, Aisha Praag, Kristen Campbell, Cynthia Carpentieri, Teri Willabus, Elizabeth Burkhardt, Elizabeth Torrone, Kevin P O'Callaghan, Kathryn Miele, Dana Meaney-Delman, Suzanne M Gilboa, Emily O'Malley Olsen, Van T Tong 2023 The Texas Medical Center Library

Substrate Electronics Dominate The Rate Of Reductive Dehalogenation Promoted By The Flavin-Dependent Iodotyrosine Deiodinase, Jeffrey M Carlson, Ayzsa Tannis, Kate R Woodworth, Megan R Reynolds, Neha Shinde, Breanne Anderson, Keivon Hobeheidar, Aisha Praag, Kristen Campbell, Cynthia Carpentieri, Teri Willabus, Elizabeth Burkhardt, Elizabeth Torrone, Kevin P O'Callaghan, Kathryn Miele, Dana Meaney-Delman, Suzanne M Gilboa, Emily O'Malley Olsen, Van T Tong

Faculty, Staff and Student Publications

Despite universal prenatal syphilis screening recommendations and availability of effective antibiotic treatment, syphilis prevalence during pregnancy and the incidence of congenital syphilis have continued to increase in the United States (1,2). Concurrent increases in methamphetamine, injection drug, and heroin use have been described in women with syphilis (3). CDC used data on births that occurred during January 1, 2018-December 31, 2021, from two states (Arizona and Georgia) that participate in the Surveillance for Emerging Threats to Pregnant People and Infants Network (SET-NET) to describe the prevalence of substance use among pregnant persons with syphilis by congenital syphilis pregnancy outcome (defined …


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