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Individual Ems Disposition In The Prehospital Setting To Predict Future Opioid Overdose And Mortality, Lillie Valliere 2020 Dominican University of California

Individual Ems Disposition In The Prehospital Setting To Predict Future Opioid Overdose And Mortality, Lillie Valliere

Global Public Health | Senior Theses

Introduction

There have been over 400,000 deaths related to prescription opioids in the US since 1999, with the highest prevalence among individuals aged 45-54 years old. However, adults between the ages of 18 and 34 have the highest prevalence of misuse of prescription opioids. With accidental overdoses as a leading cause of death, Marin County is just one community that is heavily impacted by this ongoing epidemic. Statistics related to non-fatal and fatal opioid overdoses are difficult to accurately count due to the differing ways counties may categorize cause of death, diagnoses, and other contributing factors. However, looking at 911 …


Evidence-Based Diagnosis Of Posttraumatic Stress Disorder Using Quantitative Electroencephalography, Roger Yoder 2020 Walden University

Evidence-Based Diagnosis Of Posttraumatic Stress Disorder Using Quantitative Electroencephalography, Roger Yoder

Walden Dissertations and Doctoral Studies

Diagnosing post-traumatic stress disorder (PTSD) is challenging and is currently, diagnosis through self-administered checklists. Because a diagnosis of PTSD can open up significant benefits to compensation, education, and medical care, people can tailor their responses to the checklist to help ensure a diagnosis of PTSD. The purpose of the study was to examine the utility of the quantitative electroencephalograph for diagnosing PTSD. Frequency and presence of biomarkers and alpha brain wave symmetry in the frontal and parietal lobes were examined. Research questions involved examining the presence of alpha wave imbalance across the frontal lobe and between the right and left …


On The Proposed Legalization Of Commercial Surrogacy: I Thought We Had Abolished The Sale Of Human Beings, Phyllis Chesler 2020 Phyllis Chesler Organization

On The Proposed Legalization Of Commercial Surrogacy: I Thought We Had Abolished The Sale Of Human Beings, Phyllis Chesler

Dignity: A Journal of Analysis of Exploitation and Violence

No abstract provided.


A Four-Week Fundamental Motor Skill Intervention Improves Motor Skills In Eight To 10-Year-Old Irish Primary School Children, Keith Costello, Joe Warne 2020 Setanta College

A Four-Week Fundamental Motor Skill Intervention Improves Motor Skills In Eight To 10-Year-Old Irish Primary School Children, Keith Costello, Joe Warne

Articles

Aim: To determine if a four-week fundamental motor skills intervention improves fundamental motor skills in Irish school children. Methods: 100 Primary School boys (n = 58) and girls (n = 42) participated in this study (Age 9 ± 1 years, equally divided into a control and intervention group. Proficiency was assessed qualitatively using the Fundamental Motor Skills Quotient (FMSQ) pre and post intervention, and between gender. Results: There was no change in the control group over time (p = 0.54; Mean change = 0.06 [−0.14 to 0.26]; Cohen’s d = 0.01 [Trivial]). In the intervention group, both the male (p …


The Impact Of Mental Health First Aid Training On Law Enforcement Officer Mental Health Literacy, Cindy J. Blankenship 2020 Walden University

The Impact Of Mental Health First Aid Training On Law Enforcement Officer Mental Health Literacy, Cindy J. Blankenship

Walden Dissertations and Doctoral Studies

An increasing number of juvenile offenders with untreated mental health issues are entering the justice system. Lack of adequate training of criminal justice personnel enhances the possibility of this population being arrested which is creating an overwhelming problem for stakeholders. This study sought to determine if the implementation of Mental Health First Aid (MHFA) Training impacted law enforcement officers’ (LEOs’) mental health literacy. This mixed-methods study used a quasi-experimental, one-group, pretest-posttest design, with a qualitative survey. Participants consisted of a sample of 28 LEOs from a rural Southeastern United States law enforcement agency. Study findings indicated that MHFA training increased …


The Substantiality Of The Neuroplasticity Hypothesis Of Major Depressive Disorder: The Prospective Use Of Ketamine-Like Drugs As Antidepressants, Roma Kankaria 2020 Virginia Commonwealth University

The Substantiality Of The Neuroplasticity Hypothesis Of Major Depressive Disorder: The Prospective Use Of Ketamine-Like Drugs As Antidepressants, Roma Kankaria

AUCTUS: The Journal of Undergraduate Research and Creative Scholarship

Abstract

Major depressive disorder (MDD) affects approximately 17.3 million adults in the United States each year. For more than 50 years, the serotonin hypothesis of MDD, which hypothesizes that a deficiency of monoaminergic neurotransmitters results in depression, has been the foundation for neuropsychological research. However, studies reveal that only an estimated 50% of MDD patients respond to traditional, biogenic-amine-based antidepressants (ADs), like selective serotonin reuptake inhibitors (SSRIs). Research has noted that the neuroplasticity hypothesis, which posits that weakened excitatory synaptic transmission results in depression, offers an alternative mechanism by which ketamine-like drugs lacking the abuse liability and psychoactive effects of …


Gut Microbiome Analysis In Morphine Exposure And Naltrexone-Induced Withdrawal, Nick Rapp, Sean O'Sullivan, James Schwaber 2020 Thomas Jefferson University

Gut Microbiome Analysis In Morphine Exposure And Naltrexone-Induced Withdrawal, Nick Rapp, Sean O'Sullivan, James Schwaber

Phase 1

Introduction and Objectives: Relatively little is understood about the underlying physiological changes that occur in the withdrawal state of opiate users. Research on the effects of alcohol withdrawal on the Gut-brain axis (GBA) has revealed shifts in relative numbers of specific bacterial species that correlate with increased central nervous system (CNS) inflammation via neurological crosstalk. The purpose of this research was to determine if similar shifts in the relative abundance of bacterial populations occur in the opiate withdrawal state.

Methods: Fourteen rats were randomized into four groups. Control and experimental rats were administered 75 mg morphine pellets or placebo (sugar) …


The Effect Of Perceived Physician Opinion On Breastfeeding In Women With Opioid Use Disorder Who Are Receiving Medication-Assisted Treatment, Lacey Murray, Meghan Gannon, PhD, Vanessa Short, PhD, MPH 2020 Thomas Jefferson University

The Effect Of Perceived Physician Opinion On Breastfeeding In Women With Opioid Use Disorder Who Are Receiving Medication-Assisted Treatment, Lacey Murray, Meghan Gannon, Phd, Vanessa Short, Phd, Mph

Phase 1

Women who receive medication-assisted treatment (MAT) for opioid use disorder (OUD) are less likely to breastfeed than the general population despite the many possible benefits to the newborn. The ongoing study examines the effect of perceived physician opinion on the outcome of breastfeeding in women receiving MAT for OUD. Women who were receiving MAT for OUD at Thomas Jefferson University’s Family Center were given a survey during their third trimester (n=45), and at 1 month postpartum (n=33) to gather information on the perceived opinion of their physicians on how they should feed their baby and the importance of those opinions. …


Training The Next Generation Of Family Medicine Providers Through Group Buprenorphine-Naloxone Visits, Krystina Callahan, Lara Weinstein, MD, Erica Li, MD, Sunny Lai, MD, Alexis Silverio 2020 Thomas Jefferson University

Training The Next Generation Of Family Medicine Providers Through Group Buprenorphine-Naloxone Visits, Krystina Callahan, Lara Weinstein, Md, Erica Li, Md, Sunny Lai, Md, Alexis Silverio

Phase 1

Introduction: The rise in opioid use disorders (OUD) and fatal overdoses highlight the need to expand access to and capacity for treating OUD. Medication Assisted Treatment (MAT), a medication/group visit model, done in the office setting, is an effective remedy for treating OUD. Understanding residents’ perspectives on their clinical training in MAT can inform the design of a more effective and responsive curriculum.

Methods: A qualitative study using group semi-structured interviews with residents in an urban family medicine residency rotating through a federally qualified health center. Interviews centered on strengths and weaknesses of the MAT program, resident likeliness to …


Gabapentin Drug Misuse Signals: A Pharmacovigilance Assessment Using The Fda Adverse Event Reporting System, Rachel Vickers-Smith, Jiangwen Sun, Richard J. Charnigo, Michelle R. Lofwall, Sharon L. Walsh, Jennifer R. Havens 2020 Old Dominion University

Gabapentin Drug Misuse Signals: A Pharmacovigilance Assessment Using The Fda Adverse Event Reporting System, Rachel Vickers-Smith, Jiangwen Sun, Richard J. Charnigo, Michelle R. Lofwall, Sharon L. Walsh, Jennifer R. Havens

Computer Science Faculty Publications

Background: Although there have been increasing reports of intentional gabapentin misuse, epidemiological evidence for the phenomenon is limited. The purpose of this study was to determine whether there are pharmacovigilance abuse signals for gabapentin.

Methods: Using FDA Adverse Events Reporting System reports from January 1, 2005 to December 31, 2015, we calculated pharmacovigilance signal measures (i.e., reporting odds ratio, proportional reporting ratio, information component, and empirical Bayes geometric mean) for abuse-related adverse event (AR-AE)-gabapentin pairs. Loglinear modeling assessed the frequency of concurrent reporting of abuse-related and abusespecific AEs (AS-AEs) associated with gabapentin. Findings were compared to a positive (pregabalin) and …


Proceedings Of The 2020 Undergraduate Research Conference, Ryan C. Winters, Baylee E. Guillory, Baton Rouge Community College, Grambling State University, Louisiana College, Louisiana State University, McNeese State University, Northwestern State University of Louisiana, Southern University and A&M College, University of Louisiana at Lafayette 2020 University of Louisiana at Lafayette

Proceedings Of The 2020 Undergraduate Research Conference, Ryan C. Winters, Baylee E. Guillory, Baton Rouge Community College, Grambling State University, Louisiana College, Louisiana State University, Mcneese State University, Northwestern State University Of Louisiana, Southern University And A&M College, University Of Louisiana At Lafayette

Advance: Student Research Experience

Proceedings of the 2020 Undergraduate Research Conference, University of Louisiana at Lafayette, November 9-10, 2020.


Eating Disorders And The Gap Of Education, Sara Jane Camden 2020 Walden University

Eating Disorders And The Gap Of Education, Sara Jane Camden

Walden Dissertations and Doctoral Studies

Eating disorders are described as excessive dieting, limiting food intake, and withholding of food. Over 30 million people suffer from eating disorders. Some people may also have preconceived notions that this disease is easily fixable and that eating more and stopping dieting will solve the problem. Registered nurses struggle with having preconceived ideas, a lack of confidence in their assessment skills, and fear of using the eating disorder diagnosis. Barriers that have surrounded the eating disorder mental health disease need to be addressed. The staff development project was based on the question if nursing knowledge would improve on eating disorders …


Assessing A Two-Hit Model Of Schizophrenia: Prenatal Choline Deficiency And Induced Hypofunction Of Nmda Receptors In Male And Female Long Evans Rats, Samuel Gray, Samuel W. Gray 2020 Colby College

Assessing A Two-Hit Model Of Schizophrenia: Prenatal Choline Deficiency And Induced Hypofunction Of Nmda Receptors In Male And Female Long Evans Rats, Samuel Gray, Samuel W. Gray

Honors Theses

Choline is an essential dietary nutrient essential to the development and function of the central nervous system. Prenatal choline deficiency alters hippocampal development as well as acetylcholine metabolism, leading to cognitive impairments and attentional and sensory processing deficits into adulthood. MK-801 is an NMDA receptor antagonist frequently used in rodent models of neuropsychiatric conditions, particularly schizophrenia. Acutely and sub- chronically, it causes hyperlocomotion and social withdrawal. One primary goal of the present study were to investigate prenatal choline deficiency induces a biological vulnerability to the motor deficits, anhedonia, and social impairment precipitated by low-dose sub-chronic MK-801 administration in adulthood. Another …


The Relationship Between Social Media Engagement And Psychological Well-Being In College Students At The University Of New Hampshire, Emily G. D'Antonio 2020 University of New Hampshire, Durham

The Relationship Between Social Media Engagement And Psychological Well-Being In College Students At The University Of New Hampshire, Emily G. D'Antonio

Honors Theses and Capstones

Social media use has increased substantially in recent years, and for the college-aged population, social media is often the leading method of communication. Research indicates this reliance on digital connection could have a negative impact on the health of young adults (Bagroy et al., 2017). The college years are a time of personal growth and defining actions, yet can also be burdened by mental health issues related to stress, anxiety, and depression (Hunt & Eisenberg, 2010). Acknowledging these trends, the current study explores how college students’ specific frequency and intentionality while interacting on social media relates to their psychological well-being. …


Job Self-Efficacy, Alexithymia And Secondary Traumatic Stress Among Correctional Officers, Paulette Andrea Gayle 2020 Walden University

Job Self-Efficacy, Alexithymia And Secondary Traumatic Stress Among Correctional Officers, Paulette Andrea Gayle

Walden Dissertations and Doctoral Studies

Correctional officers work in a volatile environment and are regularly exposed to inmates’ violence or cruelty. These factors negatively affect their job performance, contribute to physiological and mental health issues that could result in secondary traumatic stress (STS) symptoms. Researchers have identified job self-efficacy and alexithymia traits as mitigating factors against elevated stress. Other researchers have identified the traits as strongly associated with mental health illnesses. The purpose of this quantitative study, using a convenience sampling strategy, was to determine whether job self-efficacy and alexithymia traits were predictors of STS among a sample of 79 correctional officers working for Her …


Mental Health Service Utilization Among Urban Adolescents: The Roles Of Perceived Mental Health Problems, Attitudes Towards Professional Help, And Stigma, Yi Tak Tsang 2020 Wayne State University

Mental Health Service Utilization Among Urban Adolescents: The Roles Of Perceived Mental Health Problems, Attitudes Towards Professional Help, And Stigma, Yi Tak Tsang

Wayne State University Dissertations

Mental health among adolescents is widely acknowledged as a significant concern in the United States. Based on a national survey, Merikangas et al. (2010) found that among 13-17 year olds, 42% to 48% reported experiencing mental health concerns. It is estimated that only half of adolescents with mental health problems utilize mental health services (Costello et al., 2014). An initial study found that caregivers of disadvantaged youth appeared to function as the “gatekeepers” to mental health services (Tsang et al., 2020). Also, the results suggested that positive attitude towards professional psychological help, but not stigma, predicted service enrollment. The current …


The Long-Term Biopsychosocial Effects Of Children Reared In Blended Families, Kerene T. Brown 2020 Walden University

The Long-Term Biopsychosocial Effects Of Children Reared In Blended Families, Kerene T. Brown

Walden Dissertations and Doctoral Studies

Family dynamics have experienced an immense transformation in the last 4 decades. Children are less likely to live in a 2-parent household with parents that are both biologically related to them due to various factors. Blended families (especially the children) face many adversities during the initial stages of formation and rarely receive specialized intervention when compared to nuclear families. The purpose of this basic qualitative study was to understand the long-term biopsychosocial effects experienced by young adults who lived in a blended family household. In addition, what services or interventions were offered to newly established blended family systems were also …


Barriers To Mental Health Services Related To Stigma In Northern California, Kandalena Ary 2020 Walden University

Barriers To Mental Health Services Related To Stigma In Northern California, Kandalena Ary

Walden Dissertations and Doctoral Studies

California Senate Bill 1041 recognized mental health as a contributing barrier for individuals struggling to achieve independence from aid through the California Work Opportunity and Responsibility to Kids (CalWORKs) program to meet the needs of the state's low-income families while reducing barriers to self-sufficiency. As mental health illnesses continue to increase, the engagement and utilization of services have not increased. The purpose of this study was to explore county policy infrastructure addresses making mental health services known, accessible, and increase participation to decrease barriers in utilization of available resources. The research questions were used to examine the effectiveness of processes …


A Social Review Of The Opioid Epidemic: The History, Pathophysiology, And Effects On Rural America, Holly J. Goehring 2020 South Dakota State University

A Social Review Of The Opioid Epidemic: The History, Pathophysiology, And Effects On Rural America, Holly J. Goehring

Biology and Microbiology Graduate Students Plan B Research Projects

One of the more pressing issues in modern day health care is the nationwide heath care crisis known as the opioid epidemic. The beginning of this literature review will focus on the history of opioid use and early prescription rates, as well as the summary and definitions of the drugs involved in the current opioid epidemic. The review then shifts to the pathophysiology of addiction involving the activation of opioid receptors and opioid use disorder. The main focus of this literature review is the societal impacts of the opioid epidemic, making special reference to the economic burden and effects on …


Antidepressant Effects On Rem Sleep, Mitchel Adams 2020 South Dakota State University

Antidepressant Effects On Rem Sleep, Mitchel Adams

Biology and Microbiology Graduate Students Plan B Research Projects

Individuals who deal with depression are typically prescribed antidepressants in order to alleviate the depressive symptoms that they may be having. Polysomnographic sleep research has revealed that depression is associated with altered sleep architecture and distorted REM sleep quality.2 Specifically, increased REM sleep duration and density have proved to be markers that predict recurrence and relapse for depressed individuals. REM sleep serves to stimulate regions of the brain that are important with learning and memory consolidation. However, an increased duration of REM sleep in depressed individuals proves to be unfavorable. Antidepressants drugs aim to weaken sleep quality, which is …


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