Speech and Hearing Science Commons^™

Concordance Between The Chang And The International Society Of Pediatric Oncology (Siop) Ototoxicity Grading Scales In Patients Treated With Cisplatin For Medulloblastoma, Johnnie Bass, Jie Huang, Arzu Onar-Thomas, Kay Chang, Shaum Bhagat, Murali Chintagumpala, Ute Bartels, Sridharan Gururangan, Tim Hassall, John Heath, Geoffrey Mccowage, Richard Cohn, Michael Fisher, Giles Robinson, Alberto Broniscer, Amar Gajjar, James Gurney

Faculty Publications

BackgroundReporting ototoxicity is frequently complicated by use of various ototoxicity criteria. The International Society of Pediatric Oncology (SIOP) ototoxicity grading scale was recently proposed for standardized use in reporting hearing loss outcomes across institutions. The aim of this study was to evaluate the concordance between the Chang and SIOP ototoxicity grading scales. Differences between the two scales were identified and the implications these differences may have in the clinical setting were discussed.ProceduresAudiological evaluations were reviewed for 379 patients with newly diagnosed medulloblastoma (ages 3–21 years). Each patient was enrolled on one of two St. Jude clinical protocols that included craniospinal …

The Relationship Between Speaking Rate And Nasalance In Typical Adult Speakers, Rachel Whitney

Masters Theses

Nasometry is a non-invasive tool frequently used to measure speech resonance in clinical populations. The instrument uses an acoustic recording system to derive a measure termed nasalance, which is an estimate of the relative amount of acoustic energy emitted from the nasal cavity. Nasometry protocols do not provide detailed instructions for speaking rate control during data collection. Studies attempting to establish a relationship between speaking rate and nasalance have yielded mixed results; therefore, it is important to identify the influence of speaking rate on nasalance in a variety of speaking tasks. If rate is found to influence nasalance values, protocols …

Pedigree Structure And Kinship Measurements Of A Mid-Michigan Community: A New North American Population Isolate Identified, Joseph D. Bonner, Rachel Fisher, James Klein, Qing Lu, Ellen Wilch, Karen H. Friderici, Jill L. Elfenbein, Debra L. Schutte, Brian C. Schutte

Human Biology Open Access Pre-Prints

Previous studies identified a cluster of individuals with an autosomal recessive form of deafness that resides in a small region of mid-Michigan. We hypothesized that affected members from this community descend from a defined founder population. Using public records and personal interviews, we constructed a genealogical database that includes the affected individuals and their extended families as descendants of 461 settlers who emigrated from the Eifel region of Germany between 1836 and 1875. The genealogical database represents a 13-generation pedigree that includes 27,747 descendants of these settlers. Among these descendants, 13,784 are presumed living. Many of the extant descendants reside …

Genetics Of Peripheral Vestibular Dysfunction: Lessons From Mutant Mouse Strains, Sherri M. Jones, Timothy A. Jones

Department of Special Education and Communication Disorders: Faculty Publications

Background

A considerable amount of research has been published about genetic hearing impairment. Fifty to sixty percent of hearing loss is thought to have a genetic cause. Genes may also play a significant role in acquired hearing loss due to aging, noise exposure, or ototoxic medications. Between 1995 and 2012, over 100 causative genes have been identified for syndromic and nonsyndromic forms of hereditary hearing loss (see Hereditary Hearing Loss Homepage http://hereditaryhearingloss.org). Mouse models have been extremely valuable in facilitating the discovery of hearing loss genes, and in understanding inner ear pathology due to genetic mutations or elucidating fundamental mechanisms …

The Effect Of Metalinguistic Strategy Instruction On The Oral And Written Expression Of School-Aged Children, Karen Lara Dudek

Theses and Dissertations

Vocabulary knowledge is critical for academic success; and research has indicated that students with low vocabularies can learn metalinguistic strategies that can improve their performance in school. In this study, I investigated the impact of metalinguistic strategy instruction on the oral and written expression abilities of elementary-aged children (third grade). The strategy was the Expanding Expression Tool (EET; Smith), which can help students to increase their oral and written expression by describing words using semantic features. I used a pretest-posttest-posttest between groups design to investigate the impact of three experimental conditions on oral and written expression over a nine week …

Differences In Symptoms Among Adults With Canal Versus Otolith Vestibular Dysfunction: A Preliminary Report, Lisa Farrell, Rose Marie Rine

Physical Therapy Faculty Research

Despite the importance of symptomatology in the diagnosis of vestibular dysfunction, the qualitative nature of the symptoms related to semicircular canal (canal) versus otolith dysfunction is not fully understood. The purpose of this study was to compare symptoms, and their severity, in individuals with canal versus otolith peripheral vestibular dysfunction. A subjective tool, the Descriptive Symptom Index (DSI), was developed to enable categorization of symptoms as rotary, linear, imbalance or falls, and nondistinct. Fourteen adults were recruited and grouped based on vestibular function testing: canal only dysfunction, otolith only dysfunction, or canal and otolith dysfunction. Also, the Dizziness Handicap Inventory …

The Effects Of Cognates On Receptive And Expressive Language Among Typically Developing Preschool Second Language-Learners, Jesica B. Zavala De Guerrero

Open Access Theses & Dissertations

This exploratory study considers the facilitating effects of cognates across language of intervention, seeking to assess potential cross-language generalizations among typically developing preschool bilinguals. Nine bilingual, English-Spanish speakers of preschool age were assigned to one of three experimental groups (an English only group, a Spanish only group, and a bilingual group) or to a control condition. Children in the experimental groups were introduced to a vocabulary intervention that incorporated cognates and non-cognates. Analysis of data suggests the absence of a cognate advantage among preschool age children; furthermore limiting any possible cross-language generalizations. It is plausible to suspect that age may …

The Effects Of Cognates On Receptive And Expressive Language Among Typically Developing Preschool Second Language-Learners, Jesica B. Zavala De Guerrero

Open Access Theses & Dissertations

This exploratory study considers the facilitating effects of cognates across language of intervention, seeking to assess potential cross-language generalizations among typically developing preschool bilinguals. Nine bilingual, English-Spanish speakers of preschool age were assigned to one of three experimental groups (an English only group, a Spanish only group, and a bilingual group) or to a control condition. Children in the experimental groups were introduced to a vocabulary intervention that incorporated cognates and non-cognates. Analysis of data suggests the absence of a cognate advantage among preschool age children; furthermore limiting any possible cross-language generalizations. It is plausible to suspect that age may …

The Influence Of Gestural Learning On Oral Reading And Reading Comprehension, Rachael Joymarie Williams

Wayne State University Theses

The purpose of this study is to evaluate how gestural training may facilitate oral reading and reading comprehension of single words. For example, it is not clear whether multi-modal cues such as gesture provide an advantage over verbal cueing alone, or which type of multi-modal cues may be more effective than others in visual-verbal learning. This study examined language learning in healthy volunteers to be able to apply the effective methods for language intervention in individuals with language difficulties.

Thirty-two healthy adults were selected to participate in four different learning conditions including verbal alone, visual cue, meaningful gesture, and meaningless …

Cochlear Development And Auditory Function In The Absence Of Thyroid Hormone Transporters Mct8 And Oatp1c1, Richard Sinn

All Graduate Theses, Dissertations, and Other Capstone Projects

Thyroid hormone (TH) is essential for the development and maturation of the nervous system. The thyroid gland secretes an active form of TH, triiodothyronine, and a prohormone, thyroxine, into the blood. TH is charged, which prevents it from passively diffusing across cell membranes and thus requires cell membrane transporters to facilitate its movement into and out of cells. However, whether TH transporters are required for TH-mediated developmental events, including the auditory system, is largely unknown.

The purpose of the present study was to investigate two specific TH transporters, monocarboxylate transporter 8 (Mct8) and organic anion transporting polypeptide 1c1 (Oatp1c1), and …

Speech And Swallowing Rehabilitation In The Home: A Comparison Of Two Service Delivery Models For Stroke Survivors, Katy J. E. Stewart

Theses: Doctorates and Masters

Background and Aims

Speech and swallowing difficulties are common sequelae for people who have suffered a stroke. Recently, there has been an increase in early discharge, community rehabilitation and the use of therapy assistants to support health professionals in stroke rehabilitation. However, the impact of these factors on communication and swallowing outcomes remains under researched. This research explored Rehabilitation in the Home (RITH) Speech Pathology (SP) services for stroke survivors with dysarthria and dysphagia. More specifically, this research investigated whether traditional speech pathology interventions, supplemented with a home practice program are effective, as well as compare usual treatment to that …

Anomia Treatment Platform As Behavioral Engine For Use In Research On Physiological Adjuvants To Neurorehabilitation, Diane Kendall, Anastasia Raymer, Miranda Rose, Joellen Gilbert, Leslie J. Gonzalez Rothi

Communication Disorders & Special Education Faculty Publications

The purpose of this study was to create a "behavioral treatment engine" for future use in research on physiological adjuvants in aphasia rehabilitation. We chose the behavioral target anomia, which is a feature displayed by many persons who have aphasia. Further, we wished to saturate the treatment approach with many strategies and cues that have been empirically reported to have a positive influence on aphasia outcome, with the goal being to optimize the potential for positive response in most participants. A single-subject multiple baseline design with replication across eight participants was employed. Four men and four women, with an average …

Structural And Functional Vocal Fold Epithelial Integrity Following Injury, Ciara Leydon, Mitsuyoshi Imaizumi, David T. Yang, Susan L. Thibeault, Marvin Fried

Communication Disorders Faculty Publications

Objectives/Hypothesis: An intact epithelium is an important part of vocal fold defense. Damage to the epithelium can compromise vocal fold homeostasis and protection of the host tissue from viral and bacterial invasion. Elucidating the effects of damage on epithelial architectural and barrier integrity provides insight into the role of epithelium in protecting vocal folds. Using an animal model, we evaluated the time course of structural and functional epithelial restoration following injury. Study Design: Prospective, controlled animal study. Methods: Forty rats underwent surgery to remove vocal fold mucosa unilaterally. Larynges were harvested at five time intervals between 3 to 90 days …

Writing Development Of Spanish-English Bilingual Students With Language Learning Disabilities, Robin L. Danzak, Elaine R. Silliman

Communication Disorders Faculty Publications

This chapter addresses Spanish-speaking, English Language Learners (ELLs) in the United States (U.S.) who are sequential bilinguals; that is, oral and written English is acquired as a second language (L2) at school. Within this population, substantial variation exists with regard to individual students’ language and literacy learning experiences. The specific focus here is the writing patterns of ELLs with atypical language development, who often present with multiple complexities in authenticating their language learning profiles in both Spanish and English.

Treating Myofunctional Disorders: A Multiple-Baseline Study Of A New Treatment Using Electropalatography, Alana Mantie-Kozlowski, Kevin M. Pitt

Department of Special Education and Communication Disorders: Faculty Publications

Purpose: This study assessed the benefit of using electropalatography (EPG) in treatment aimed at habilitating individuals with nonspeech orofacial myofunctional disorders (NSOMD).

Method: The study used a multiple-baseline design across 3 female participants who were referred for an evaluation and possible treatment of their NSOMD. Treatment sessions were 30 min and provided twice weekly. Participant 1 received 8 treatments, Participant 2 received 6 treatments, and Participant 3 received 4 treatments. The patterns of sensor activation produced when participants’ tongues made contact with the electropalate during saliva swallows were compared with the patterns of age-matched peers. Individualized goals were developed on …

Services And Information Provided To Mothers In El Paso/Juarez Region, Christina Y. Perez

Open Access Theses & Dissertations

It is estimated that the Latino population will be the majority of the population by 2050 in the United States. There is research supporting the notion that the Latino population is under-served and under-diagnosed regarding physical and mental illnesses. Appropriately informed professionals and parents are the first step to reducing the number of under-diagnosed children that do not receive the treatment they require. This survey was conducted to determine what information Latino mothers from low socio-economic backgrounds possess concerning the developmental milestones of their children and the services available to them. Fifty mothers responded to the survey. Results revealed that …

Potential Influences Of Compliance For Short-Term Recovery From Sports-Related Concussion, Erin R. Ewing

Open Access Theses & Dissertations

Currently, treatment of sports-related concussion dictates the prescription of physical and cognitive rest to allow the injured brain to recover and for concussion-related symptoms to subside. However, clinicians who prescribe rest are often met with resistance from athletes who do not recognize its therapeutic value in the recovery process. Research has shown that athletes often fail to comply with rest recommendations, resulting in protracted recovery and the persistence of symptoms. Method: This study employed a three-group pretest-posttest experimental design to compare the effects of three different concussion management protocols. Participants were recently concussed athletes ages 18-25 seen in the UTEP …

A Pilot Study: Examining The Microstructural And Macrostructural Narrative Measures In Bilingual Preschool Aged Children, Caroline Esparza

Open Access Theses & Dissertations

Purpose: Research has identified narratives as accurate and reliable predictors of language skills, yet little is documented on the microstructural and macrostructural narrative production of preschool aged bilingual children. This pilot study examined the microstructure and macrostructure elements of narratives in these children to provide preliminary data for further research.

Method: This study examined the narrative skills of 11 bilingual children between the ages of 3 and 4. Narrative retells in Spanish were elicited and were analyzed for the microstructural measures of lexical diversity (NDW) and productivity (TNW and MLU) measures and for the their macrostructural Narrative Scoring Scheme (NSS) …

The Impact Of Interface Design During An Initial High-Technology Aac Experience: A Collective Case Study Of People With Aphasia, Aimee R. Dietz, Kristy S.E. Weissling, Julie Griffith, Miechelle L. Mckelvey, Devan Macke

Department of Special Education and Communication Disorders: Faculty Publications

The purpose of this collective case study was to describe the communication behaviors of five people with chronic aphasia when they retold personal narratives to an unfamiliar communication partner using four variants of a visual scene display (VSD) interface. The results revealed that spoken language comprised roughly 70% of expressive modality units; variable patterns of use for other modalities emerged. Although inconsistent across participants, several people with aphasia experienced no trouble sources during the retells using VSDs with personally relevant photographs and text boxes. Overall, participants perceived the personally relevant photographs and the text as helpful during the retells. These …

Supporting Narrative Retells For People With Aphasia Using Augmentative And Alternative Communication: Photographs Or Line Drawings? Text Or No Text?, Julie Griffith, Aimee R. Dietz, Kristy S.E. Weissling

Department of Special Education and Communication Disorders: Faculty Publications

Purpose: The purpose of this study was to examine how the interface design of an augmentative and alternative communication (AAC) device influences the communication behaviors of people with aphasia during a narrative retell task.

Method: A case-series design was used. Four narratives were created on an AAC device with combinations of personally relevant (PR) photographs, line drawings (LDs), and text for each participant. The narrative retells were analyzed to describe the expressive modality units (EMUs) used, trouble sources experienced, and whether trouble sources were repaired. The researchers also explored the participants’ perceived helpfulness of the interface features.

Results: The participants …