Alternative and Complementary Medicine Commons^™

Combination Of Investigational Cell-Based Therapy And Deep Brain Stimulation To Alter The Progression Of Parkinson’S Disease, Nader El Seblani

Theses and Dissertations--Pharmacy

Parkinson’s disease (PD) is the second most common neurodegenerative disorder and the motor symptoms are caused by progressive loss of midbrain dopamine neurons. There is no current treatment that can slow or reverse PD. Our current “DBS-Plus” clinical trial (NCT02369003) features the implantation in vivo of autologous Schwann cells (SCs) derived from a patient’s sural nerve into the substantia nigra pars compacta (SNpc) in combination with Deep Brain Stimulation (DBS) therapy for treating patients with advanced PD.

The central hypothesis of our research is that transdifferentiated SCs within conditioned nerve tissue will deliver pro-regenerative factors to enhance the survival of …

Mindfulness Meditation As A Treatment For Generalized Anxiety Disorder (Gad), Punit Patel

Capstone Showcase

Generalized anxiety disorder (GAD) involves dysregulation of worry for more than 6 months. Symptoms include fatigue, insomnia and irritability. Medications such as SSRIs may cause constipation, lower libido and cause withdrawal symptoms when discontinued. Alternative therapies like mindfulness meditation teach patients breath awareness and to redirect unwanted negative thoughts to positive ones. This paper examines the efficacy of mindfulness meditation treatment (I) for managing symptoms of anxiety (O) in adult patients with mild-moderate GAD (P) in comparison to stress management education (C).

Efficacy Of Curcumin In The Treatment Of Advanced Pancreatic Ductal Adenocarcinoma Compared To Sole Gemcitabine Chemotherapy, Komal Vadodaria

Capstone Showcase

Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer death in both men and women. Due to the difficulty of diagnosing this malignancy until it has progressed to an advanced stage, treatment is often difficult, expensive and ineffective. The first line treatment for PDAC is Gemcitabine chemotherapy. However, due to its extensive side effect profile and the early chemo-resistance the PDAC cells develop against Gemcitabine, the need for alternative therapeutic methods to manage treatment is necessary. Therefore, this review analyzes if in individuals with advanced pancreatic ductal adenocarcinoma [P], does the addition of curcumin with the standard Gemcitabine chemotherapy …

The Efficacy Of Adding Eicosapentaenoic Acid To Statin Monotherapy In The Prevention Of Acute Coronary Syndrome In Patients With Coronary Artery Disease, Carlo Escudero

Capstone Showcase

Introduction: Coronary artery disease (CAD) is a chronic medical condition caused by the buildup of plaque within the coronary artery endothelium. If left untreated it can progress to an acute coronary syndrome (ACS) which can lead to myocardial ischemia and death. Statins are lipid lowering agents used in clinical practice for the medical management of CAD. However, incidence of major adverse cardiovascular (CV) events still occurs despite optimal statin therapy. Currently eicosapentaenoic acid (EPA) has been promoted to be effective when added to statin therapy in lowering the incidence of CV events in patients with hypercholesterolemia. This paper will address …

Efficacy Of Adjunct Acupuncture (Insertive And Non-Insertive) In The Treatment Of Neonates With Neonatal Abstinence Syndrome, Kali Thibault

Capstone Showcase

Introduction: Neonatal Abstinence Syndrome (NAS) is a condition that affects newborn infants exposed to opioids in utero. NAS is becoming increasingly more prevalent due to the ongoing opioid epidemic. Current treatment for NAS is primarily morphine or buprenorphine. Even on these treatments, infants with NAS often still have symptoms of withdrawal, requiring high doses of medication and extended hospital stays. Acupuncture therapy has been shown to decrease withdrawal symptoms in adults, so researchers are now looking to use this non-pharmacological treatment on infants with NAS.

Methods: A literature search was performed using Google Scholar, PubMed, and EBSCOhost in November of …

Oral Contraceptives As Possible Acl Injury Prevention Method, Haley Schweizer

Capstone Showcase

ABSTRACT

Introduction: Anterior Cruciate Ligament (ACL) injuries are an upsetting setback for many athletes that require a long and costly recovery process. The injury rates are four times greater in women than men. Preventative measures that help to prevent ACL injuries are limited to stretching and strengthening. Therefore, this review aims to investigate if oral contraceptive [I] usage provides a possible new avenue for prevention of ACL injury [O] in young female athletes (ages 18-30) [P] compared to those that do not take oral contraceptives [C].

Methods: A literature review was performed though PubMed, Google Scholar, SCOPUS Database, and ClinicalKey …

Antibacterial, Antifungal, Antioxidant Activity And Polyphenol Content Of Aerial Parts And Bulbs Of Allium Schugnanicum., Saidbeg Satorov, F. Mirzoeva, Sh. Kurbonbekova, Sh. Satorov, M. Vakhidova, Vyacheslav Dushenkov

Publications and Research

Objective: То study of antibacterial, antifungal and antioxidant activity, and content of polyphenols in the bulb and aerial parts of an endemic species of onion A. schugnanicum. Methods: An ethanol-based extract was prepared from fresh plants. Total polyphenolic content (Folin) and ABTS antioxidant capacity assays were used to characterized extracts. Extracts obtained from bulbs, peduncle, and seeds demonstrated antibacterial activity against the reference Staphylococcus aureus (ATCC 4929), Pseudomonas aeruginosa (ATCC 4930) and Klebsiella pneumoniae (ATCC 4927) strains, as well as against the hospital strains of the same types of bacteria, i.e. strains isolated from inpatient surgical patients. Results: The study …

The Efficacy Of Yoga As An Adjunctive Therapy To Standard Multidisciplinary Care In The Treatment Of Female Patients Presenting With Cognitive Eating Disorder Symptoms, Cassidy Nagle

Capstone Showcase

Introduction: Current treatment of patients exhibiting cognitive eating disorder symptoms is standard multidisciplinary care (SMDC) involving behavioral therapy, medical management and dietetics. Because these symptoms often persist or relapse despite treatment, research has begun to explore adjunctive therapies like yoga for this population. This review will explore seven studies in order to analyze the effect of yoga (I) on cognitive eating disorder symptoms (O) in teenage and adult females (P) when added to SMDC compared to symptom reduction with SMDC alone (C).

Methods: A literature search was conducted in PubMed, Academic Search Ultimate and Google Scholar starting November 2018. Seven …

A Systematic Review: Effectiveness Of Complementary Therapies On Mental Status Of Pediatric Oncology Patients, Sara Fredricks, Jessica Lloyd, Whitney Wendling

Williams Honors College, Honors Research Projects

Children with cancer frequently suffer from depression, anxiety, feelings of hopelessness, and psychological stresses related to knowledge of potential risks, associated treatments, and the illness itself. These psychological problems can cause many additional physiological problems for these already chronically ill patients and may be detrimental to their overall health. The purpose of this systematic review is to review and critically appraise the evidence to determine if the use of Complementary and Alternative Methods (CAM), along with standardized care, affects mental health outcomes in pediatric cancer patients. Twenty-one primary source publications between 2013 and 2019 were analyzed for this systematic review. …

The Impact Of Lifestyle Medicine On Nonalcoholic Fatty Liver Disease, Kelli L. Noble

DNP Research Projects

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. The main risk factor for the development of NAFLD is metabolic syndrome. Women are at greatest risk, typically in their 5th to 6th decade of life. The more aggressive form of NAFLD is nonalcoholic steatohepatitis (NASH) which is characterized by inflammation associated with NAFLD. NASH has the greatest tendency to progress into cirrhosis. However, lifestyle intervention has been shown to effectively treat, and even reverse NAFLD. The purpose of this quantitative, quasi-experimental study was to lend additional research and demonstrate improvement in NAFLD through lifestyle intervention with 1) …

Evaluating The Impact Of Malaria Education On Student Missionaries, Julie Mckinney

DNP Research Projects

Malaria has been studied for years, and yet remains one of the most significant vector-borne diseases that travelers encounter in malaria-endemic regions (CDC, 2019). Education is noted to be critical in disease prevention, management, and eradication. Student missionaries are at high risk for infection and can have a global influence that is improved through education. A pilot study was conducted on eleven students with a pre-test and post-test design after a malaria education webinar. The purpose of this pilot study was to assess the baseline level of education in student missionaries, as well as to assess the effect of malaria …

A Qualitative Investigation Into The Influence Of A Mental Health Physical Activity Intervention On University Students, Heather M. Tunks

Theses and Dissertations (Comprehensive)

Objective

Among the university student population, mental illnesses are highly prevalent. Adults aged 20-30 years have the highest rates of mood and anxiety disorders than any other age group, with approximately 12.0% diagnosed with an anxiety disorder and 7.0 to 9.0% experiencing clinical depression (Nunes et al., 2014; Pedrelli, Nyer, Yeung, Zulauf, & Wilens, 2015). Reducing or preventing the effects of mental illness among this population may have lifelong implications including improvements in coping and management of mental illness throughout the lifespan(Jaworska, DeSomma, Fonseka, Heck, & MacQueen, 2016). This research examines the lived experiences of volunteers and participants in a …

Exploring The Use Of A Mindfulness Based Yoga Intervention For Children With Severe Asthma, Sharon Lack

Theses and Dissertations

Introduction: A diagnosis of severe asthma greatly impacts the physical and psychological health of children. Often experiencing increased stress, decreased physical activity, and increased exacerbations, children with severe asthma frequently exhibit poor health outcomes. Mindful yoga is a complementary health approach that may improve the physical and psychological well-being of children with severe asthma. The aims of this research were to evaluate the tolerability, feasibility, acceptability, and preliminary effects of a mindful yoga intervention in children with severe asthma. A novel theoretical framework encompassing concepts from three vulnerability nursing theories guided the research.

Methods: A mixed methods pilot …

Effects Of Aromatherapy On Academic Success, Perceived Stress, And Coping Skills Of Graduate Students, Lakisha S. Witter

All Graduate Theses, Dissertations, and Other Capstone Projects

This quasi-experimental study will explore whether the use of aromatherapy increases students’ academic success and coping skills and decreases the level of perceived stress in graduate college students.

Alternative Therapy For Veterans Diagnosed With Post-Traumatic Stress Disorder, Shannon Rae Hill

Walden Dissertations and Doctoral Studies

An increasing number of veterans diagnosed with post-traumatic stress disorder (PTSD) has led to an increased demand for treatment within the Veteran Affairs health care system. Presently, veterans diagnosed with PTSD receive psychotropic medications and intermittent therapy sessions. Nurses are challenged to educate veterans about other health care issues based on verbalized side effects from prescribed PTSD medications limiting veterans’ ability to focus. Identifying alternative treatment options may improve treatment choices, reduce side effects, and promote positive outcomes for veterans with PTSD. This systematic review provided evidence-based practice information by addressing whether alternative therapy such as biofeedback would improve the …

Beyond Dissociation And Appropriation: Evaluating The Politics Of U.S. Psychology Via Hermeneutic Interpretation Of Culturally Embedded Presentations Of Yoga, Genelle N. Benker

Antioch University Dissertations & Theses

Psychology in the United States (U.S.) is partially constituted by a cultural history of intellectual imperialism that undermines its altruistic intent and prevents disciplinary reflexivity. The scholarship and clinical application of Yoga exemplifies the way U.S. psychology continues to give lived authority to imperialism as part of the neoliberal agenda. Through a hermeneutic literature analysis of two source Yogic texts and peer-reviewed articles that exemplify the dominant discourse on Yoga in U.S. psychology, this dissertation identified themes that describe culturally embedded presentations of Yoga and their sociopolitical implications. Through interpretation, Yoga was conceptualized as: (a) a 5,000 year-old tradition that …

Discovery And Optimization Of Anti-Cancer Properties Of Traditional Herbal Medicines Using Zebrafish-Human Tumor Xenografts, Ashleigh M. Solheim

Honors College Theses

Cancer is one of the most well-known diseases around the world. It hurts everyone in some way, whether they have it themselves or they know someone that is diagnosed. But the problem is not just this brutal disease, the problem is its invasive treatments. The most common treatments for cancer have harmful and painful side-effects that occur in most cases. As a solution to invasive cancer treatments, this experiment is testing herbal medications Neem, Nilavembu, Ashwagandha and Tulsi as potential nontoxic cancer treatments. First, the maximum tolerable dosage for each herbal agent was found. This dosage was used for the …

The Effect Of Hibiscus.Sabdariffa. L On Blood Pressure And Arterial Stiffness In Humans, Basirat Tolulope Shittu

Dissertations, Master's Theses and Master's Reports

Cardiovascular diseases (CVD) are the foremost cause of death worldwide. The main risk factor for CVD is uncontrolled hypertension (HTN). The prescription of only anti-hypertensive regimens in the management of HTN is becoming more challenging due to the high cost and adverse effects linked to the persistent usage of the drugs. Eighteen participants completed the study by consuming 2g of Hibiscus sabdariffa or oolong tea twice daily for six weeks. We lost an additional twelve participants in the study due to the COVID-19 pandemic. Central arterial stiffness was analyzed as cfPWV using applanation tonometry technique. The HS tea intervention (n=11) …

Hear Me Roar, Abigail R. Seethoff

Graduate Student Theses, Dissertations, & Professional Papers

Hear Me Roar, a compilation of personal essays interspersed with short forms, grapples with the nuances of compliance versus autonomy in the context of the male gaze, beauty standards, and pop culture. The collection also explores what it means to treasure something—another person, an object—and how to express and deepen that affection.

A Short Remark On Bong Han Duct System (Pvs) As A Neutrosophic Bridge Between Eastern And Western Medicine Paradigms, Victor Christianto, Florentin Smarandache

Branch Mathematics and Statistics Faculty and Staff Publications

In a previous paper in this journal (IJNS), it is mentioned about a possible approach of “curemony” as a middle way in order to reconcile Eastern and Western’s paradigms of medicine [1]. Although it is known in literature that there are some attempts to reconcile between Eastern and Western medicine paradigms, known as “integrative medicine,” here a new viewpoint is submitted, i.e. Bong Han duct system (PVS), which is a proof of Meridian system, can be a bridge between those two medicine paradigms in neutrosophic sense. This can be considered as a Neutrosophic Logic way to bridge or reconcile the …