Alternative and Complementary Medicine Commons^™

Antioxidant And Cytotoxic Potential Of Potentized Preparation Of Cordyceps Sinensis In Vitro In Cancer Cell Lines, Vettrivel Arul, Rajamanickam Kandasamy, Mary Adharshna Sp

Indian Journal of Research in Homoeopathy

Background: The parasitic fungus Cordyceps sinensis (Ophiocordyceps sinensis) has been discovered in lepidopteran larvae, having known antitumor effects. Testing potentized Cordyceps sinensis in cancer cells could help broaden Homoeopathy cancer therapeutics.

Objectives: The objectives of the study were to evaluate the antioxidant and cytotoxicity activity of potentized preparation of Cordyceps sinensis in carcinoma cell-lines.

Methods: In this in vitro study, antioxidant activity was analyzed by the 2,2-diphenyl-1-picryl-hydrazyl-hydrate assay and the dilution with more antioxidant potential was further analyzed for cytotoxicity, using 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyltetrazolium bromide assay on various carcinoma cell lines: Breast cancer cell line (MCF-7), liver cancer cell line (HePG2), …

A Randomised, Double-Blind, Placebo-Controlled And Parallel-Arm Trial To Assess The Effect Of Homoeopathic Medicines On Chronic Rhinosinusitis, Praveen Oberai, Subhash Kaushik, Sunil Ramteke, M N. Sinha, Sarabjit Sarkar, Kalpana Gautam, Arvind Kumar, Harleen Kaur, Raj Kumar Manchanda, Roja Varanasi

Indian Journal of Research in Homoeopathy

Background: Chronic rhinosinusitis (CRS) is a significant health problem impacting health related quality of life.

Objectives: This study assesses the efficacy of individualised homoeopathy (IH) in LM potency in CRS.

Methods: A randomised, double-blind and placebo-controlled trial on patients with CRS was undertaken at four institutes, from July 2012 to December 2013. Eligible participants were randomised to IH in LM-potencies (n = 60) or a similar placebo (n = 60). Primary outcome was change in the total symptoms score (TSS) (area under the curve [AUC]) and in sinus nasal outcome test 22 over 3 months. Intention-to-treat approach was used …

Can The Sweet Pills Restore The Smiles Of Autistic Children?, Deepthi Gilla, K.C. Muraleedharan

Indian Journal of Research in Homoeopathy

The second of April marks World Autism Awareness Day (WAAD), every year globally. WAAD was designated by the United Nations in 2007 to help end stigmatization and discrimination against those with Autism and their caregivers. It aims to raise understanding and awareness of this global health issue at all levels of society. The alarming increase in prevalence (1 in 100-WHO) and potentially lifelong disabling nature of the disorder demands awareness as early identification and intervention are pivotal in the management of Autism.

Advancing Health Equity In The Us Military, James D. Mancuso, John Young, Jennifer Rusiecki, Shauna Stahlman, Natasha Schvey, Toya Randolph, Candy Wilson, Catherine Witkop, Patrick Hyde, Althea Green, Patcho Santiago, Donald Shell, Tracy Sbrocco

Journal of Health Disparities Research and Practice

Eliminating health disparities and achieving health equity are central to US national health objectives and the Military Health System’s “quadruple aim,” which has readiness as its core aim. Because military service members enjoy universal eligibility for health care, it is sometimes assumed that health disparities do not exist in the Department of Defense (DoD). However, while some studies have shown that disparities have been attenuated or eliminated in the DoD, others suggest that significant disparities remain. Reasons these disparities may remain include that universal eligibility for care does not necessarily result in equal to access to care, and that equal …

Development Of A Method For Identifying And Quantifying Epicatechin In Cinnamon Extract Supplement Capsules, Danielle Valls

Annual Research Symposium

No abstract provided.

The Effects Of Vitamin B1 Analog, Benfotiamine, On The Prevention Of Non-Small Cell Lung Cancer, Emely Fernandez, Hannah Christensen, Kota A. Ramana

Annual Research Symposium

No abstract provided.

Carvacrol Regulates Endotoxin -Induced Arachidonic Acid Metabolism., Aliea M. Jalali, Spencer Norton

Annual Research Symposium

Plant-derived essential oil prevents endotoxin-induced inflammatory response

Poster Presentation: Acupressure Modality Effectiveness: Research Results For Pain And Anxiety Poster, Deanna Waggy Otr, Carroll Noel Mozer Otr/L, Marilyn Zurwaski Otr/L

Journal of Transformative Touch

According to recent studies, including Monson et all, JACM, 2019, there is growing evidence for the effective and safe use of acupressure as a non-pharmacological approach to reducing pain and anxiety. Acupressure can quiet the mind, promoting a sense of well-being by decreasing anxiety.

A collaborative retrospective analysis of self-rated pain and anxiety scores before and immediately after administration of a stress release protocol indicate that acupressure is a highly satisfactory complementary therapy. Results were clinically significant for a decrease in self-rated pain and anxiety scores.

Occupational therapy practitioners as well as those who use the Kawa model of reference …

Acupressure Modality Effectiveness: Research Results For Pain And Anxiety, Deanna Waggy Otr, Carroll Noel Mozer Otr/L, Marilyn Zurwaski Otr/L

Journal of Transformative Touch

According to recent studies, including Monson et all, JACM, 2019, there is growing evidence for the effective and safe use of acupressure as a non-pharmacological approach to reducing pain and anxiety. Acupressure can quiet the mind, promoting a sense of well-being by decreasing anxiety.

A collaborative retrospective analysis of self-rated pain and anxiety scores before and immediately after administration of a stress release protocol indicate that acupressure is a highly satisfactory complementary therapy. Results were clinically significant for a decrease in self-rated pain and anxiety scores.

Occupational therapy practitioners as well as those who use the Kawa model of reference …

Neuroprotective Effects Of Green Tea (Camellia Sinensis) And Broccoli (Brassica Oleracea) Extracts In An In Vitro Model Of Multiple Sclerosis, Sara Taha Fathallah

Theses and Dissertations

Multiple Sclerosis (MS) is a neurodegenerative autoimmune disease in which the immune system attacks the central nervous system (CNS) resulting in demyelination. Currently, there is no specific treatment for MS. Here, we propose testing the neuroprotective potential of Green tea (Camellia sinensis), and Broccoli (Brassica oleracea) extracts in an in vitro model of multiple sclerosis.

Methods and Results: Green tea and Broccoli plant extracts were analyzed with GC-MS and tested for their neuroprotective effects in an in vitro MS model using Cuprizone (CPZ) on the Human neuroblastoma SH-SY5Y cell line. Cell viability assays proved the safety of the extracts …

Effects Of Date Seed (Phoenix Dactylifera) Extract In An Animal Model Of Diabetes Mellitus, Sara Refaat

Theses and Dissertations

Diabetes mellitus is a chronic illness and a global epidemic. The commercial diabetic medicines available are expensive and have several adverse effects. Alternative natural products are still being sought for. Date seeds ( Phoenix dactylifera) are either thrown away as garbage or utilized as animal feed. The use of seed extract as an alternative therapy for diabetes offers a cost-effective and all-natural method for managing the disease. Methods Sprague dawley rats were randomly distributed into groups with a sample size of 4 rats per group. Date seed powder was boiled producing a 10% date seed extract which was administered in …

Milk Diets, Grape Cures, And Bananas Galore: An Examination Of Past And Present Wellness Culture Turned Sour, Jacqueline Alnes

Sustainability Research & Practice Seminar Presentations

Professor Jacqueline Alnes, English - Milk Diets, Grape Cures, and Bananas Galore: An Examination of Past and Present Wellness Culture Turned Sour

Formulation Of Encapsulated Nanoparticles Of Leek Extract As Antimicrobial And Anticancer Agent, Rawan Hassan Mohamed Elghanam

Theses and Dissertations

Leek extract (LEK) has broad therapeutic activity. However, plant extract use has many drawbacks, which could be resolved using nanocarriers. The purpose of this research work was to prepare chitosan nanoparticles (CS NPs) encapsulating LEK and investigate their antioxidant, antimicrobial, and anticancer activity. Gas chromatography-mass spectroscopy was used to determine the LEK components. The CS-LEK NPs were produced by tripolyphosphate (TPP) crosslinking with chitosan (CS) the ionic gelation methodology. The particle size was 331 nm, zeta potential (ZP) was 28.9 mv, polydispersity index (PDI) was 0.4, encapsulation efficiency (EE) was 65.6%, and loading capacity (LC) was 28.8 % of the …

Therapeutic Options For Covid-19: Drug Repurposing Of Serine Protease Inhibitor Against Tmprss2, Mohammad Wildan Abiyyi, Surya Dwira, Arleni Bustami, Linda Erlina

Indonesian Journal of Medical Chemistry and Bioinformatics

The SARS-Coronavirus 2 (SARS-CoV-2) outbreak is a serious global public health threat. Researchers around the world are conducting mass research to control this epidemic, starting from the discovery of vaccines, to new drugs that have specific activities as antivirals. Drug repurposing is a potential method of using drugs with known activity for reuse as COVID-19 therapy. This method has the advantage that it can reduce costs and also the duration in the development of potential drugs. The initial step in drug repurposing can be done computationally to determine the effectiveness and specificity of the drug on the target protein. Molecular …

Labeling Compliance And Online Claims For Ayurvedic Herbal Supplements On The U.S. Market Associated With The Purported Treatment Of Covid-19, Chevon R. Jordan, Calin M. Harris, Miranda I. Miranda, Diane Y. Kim, Rosalee S. Hellberg

Food Science Faculty Articles and Research

During the COVID-19 pandemic, many consumers increased their use of supplements that claimed to support immune health, including Ayurvedic preparations. The goal of this study was to analyze labeling compliance and online claims for Ayurvedic herbal supplements associated with the purported treatment of COVID-19. The physical product labels for 51 herbal supplements labeled as ginger, tulsi/holy basil, amla, vacha/calamus root, guduchi/giloy, cinnamon, ashwagandha, tribulus, or turmeric were assessed for U.S. regulatory compliance. Disease claims, structure/function claims, and general well-being claims were also examined. The online listings for products purchased online (n = 42) were examined for claims and for the …

A Focused Review Of Multidimensional Well-Being Assessments, Samantha Schonhardt, Stephanie Sullivan, Rebecca Shisler Marshall

Journal of Wellness

Introduction: Interest in the topic of well-being continues to grow and has resulted in the creation of a variety of well-being assessments. However, each assessment often brings its own terminology, theories, definitions, and dimensions. This creates a muddled research base that produces inconsistencies in the field of well-being. Therefore, the aim of this review was to identify assessments that measure multiple dimensions of well-being, catalogue and group the dimensions into categories, and develop definitions for the categories based on the conceptualizations in the literature. In doing so, the dimensionality of well-being portrayed in the literature can be better understood. …

Virtual Screening On Indonesian Herbal Compounds As Sars-Cov-2 Spike (S2) Glycoprotein Inhibitors: Pharmacophore Modelling & Molecular Docking Approaches, Syailendra Karuna Sugito, Artha Uli Cristina, Putri Saskia Harimurti, Gabriella Regita Cendani, Fauzi Azhar Insani, Linda Erlina, Rafika Indah Paramita, Fadilah Fadilah

Indonesian Journal of Medical Chemistry and Bioinformatics

Background: There are still no specific treatments for coronavirus disease (COVID-19) until present days. Several studies have been conducted to determine whether herbal medicine can be an option to be used as a definitive medicine for COVID-19. S2 subunit of spike protein which is responsible for SARS-CoV-2 entry to the host cell, is a potential drug target to inhibit the viral infection. In this study, we aimed to find some compounds from the HerbalDB database that have potential as SARS-CoV-2 spike (S2) glycoprotein inhibitor.

Methods: The 6LXT protein was used as the target protein. The procedure in this study consisted …

Mindfulness Based Stress Reduction Techniques In Chronic Illness, Anna Celia Gil

Electronic Theses and Dissertations

Abstract

Chronic stress and its effect on both physical and mental health have been a topic of increasing interest in the past several decades. There is mounting evidence that recurrent, persistent stress of both a physiologic and psychological nature leads to a dysfunction in the hypothalamic pituitary axis (HPA), the system which helps the body recover and adapt to short term stress. In long term stress, this HPA dysfunction leads to impairment of the immune and neuroendocrine systems resulting in chronic low-grade inflammation. This type of chronic inflammation acts as a precursor to several chronic illnesses such as diabetes, hypertension, …

Urban Land-Based Healing: A Northern Intervention Strategy, Nicole Redvers, Melanie Nadeau, Donald Prince

Indigenous Health Faculty Publications

Urban Indigenous populations face significant health and social disparities across Canada. With high rates of homelessness and substance abuse, there are often few options for urban Indigenous Peoples to access land-based healing programs despite the increasingly known and appreciated benefits. In May 2018, the first urban land-based healing camp opened in Yellowknife, Northwest Territories, Canada, one of the first to our knowledge in Canada or the United States. This camp may serve as a potential model for an Indigenous-led and Indigenous-based healing camp in an urban setting. We seek to present preliminary outcome data from the healing camp in a …

Centering Culture In The Treatment Of Opioid Use Disorder With American Indian And Alaska Native Communities: Contributions From A National Collaborative Board, Katherine A. Hirchack, Melanie Nadeau, Angel Vasquez, Alexandra Hernandez-Vallant, Kyle Smith, Cuong Pham, Karen Anderson Oliver, Paulette Baukol, Karen Lizzy, Raquel Shaffer, Jalene Herron, Aimee M. C. Campbell, Kamilla L. Venner

Indigenous Health Faculty Publications

American Indian/Alaska Native (AI/AN) communities are disproportionally impacted by the opioid overdose epidemic. There remains a dearth of research evaluating methods for effectively implementing treatments for opioid use disorder (OUD) within these communities. We describe proceedings from a 2-day Collaborative Board (CB) meeting tasked with developing an implementation intervention for AI/AN clinical programs to improve the delivery of medications to treat OUD (MOUD). The CB was comprised of Elders, cultural leaders, providers, individuals with lived experience with OUD, and researchers from over 25 communities, organizations, and academic institutions. Conversations were audio-recorded, transcribed, and coded by two academic researchers with interpretation …