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Therapeutic Options For Covid-19: Drug Repurposing Of Serine Protease Inhibitor Against Tmprss2, Mohammad Wildan Abiyyi, Surya Dwira, Arleni Bustami, Linda Erlina 2023 Master's Programme in Biomedical Science, Faculty of Medicine, Universitas Indonesia

Therapeutic Options For Covid-19: Drug Repurposing Of Serine Protease Inhibitor Against Tmprss2, Mohammad Wildan Abiyyi, Surya Dwira, Arleni Bustami, Linda Erlina

Indonesian Journal of Medical Chemistry and Bioinformatics

The SARS-Coronavirus 2 (SARS-CoV-2) outbreak is a serious global public health threat. Researchers around the world are conducting mass research to control this epidemic, starting from the discovery of vaccines, to new drugs that have specific activities as antivirals. Drug repurposing is a potential method of using drugs with known activity for reuse as COVID-19 therapy. This method has the advantage that it can reduce costs and also the duration in the development of potential drugs. The initial step in drug repurposing can be done computationally to determine the effectiveness and specificity of the drug on the target protein. Molecular …


Labeling Compliance And Online Claims For Ayurvedic Herbal Supplements On The U.S. Market Associated With The Purported Treatment Of Covid-19, Chevon R. Jordan, Calin M. Harris, Miranda I. Miranda, Diane Y. Kim, Rosalee S. Hellberg 2023 Chapman University

Labeling Compliance And Online Claims For Ayurvedic Herbal Supplements On The U.S. Market Associated With The Purported Treatment Of Covid-19, Chevon R. Jordan, Calin M. Harris, Miranda I. Miranda, Diane Y. Kim, Rosalee S. Hellberg

Food Science Faculty Articles and Research

During the COVID-19 pandemic, many consumers increased their use of supplements that claimed to support immune health, including Ayurvedic preparations. The goal of this study was to analyze labeling compliance and online claims for Ayurvedic herbal supplements associated with the purported treatment of COVID-19. The physical product labels for 51 herbal supplements labeled as ginger, tulsi/holy basil, amla, vacha/calamus root, guduchi/giloy, cinnamon, ashwagandha, tribulus, or turmeric were assessed for U.S. regulatory compliance. Disease claims, structure/function claims, and general well-being claims were also examined. The online listings for products purchased online (n = 42) were examined for claims and for the …


Virtual Screening On Indonesian Herbal Compounds As Sars-Cov-2 Spike (S2) Glycoprotein Inhibitors: Pharmacophore Modelling & Molecular Docking Approaches, Syailendra Karuna Sugito, Artha Uli Cristina, Putri Saskia Harimurti, Gabriella Regita Cendani, Fauzi Azhar Insani, Linda Erlina, Rafika Indah Paramita, Fadilah Fadilah 2023 Universitas Indonesia

Virtual Screening On Indonesian Herbal Compounds As Sars-Cov-2 Spike (S2) Glycoprotein Inhibitors: Pharmacophore Modelling & Molecular Docking Approaches, Syailendra Karuna Sugito, Artha Uli Cristina, Putri Saskia Harimurti, Gabriella Regita Cendani, Fauzi Azhar Insani, Linda Erlina, Rafika Indah Paramita, Fadilah Fadilah

Indonesian Journal of Medical Chemistry and Bioinformatics

Background: There are still no specific treatments for coronavirus disease (COVID-19) until present days. Several studies have been conducted to determine whether herbal medicine can be an option to be used as a definitive medicine for COVID-19. S2 subunit of spike protein which is responsible for SARS-CoV-2 entry to the host cell, is a potential drug target to inhibit the viral infection. In this study, we aimed to find some compounds from the HerbalDB database that have potential as SARS-CoV-2 spike (S2) glycoprotein inhibitor.

Methods: The 6LXT protein was used as the target protein. The procedure in this study consisted …


A Focused Review Of Multidimensional Well-Being Assessments, Samantha Schonhardt, Stephanie Sullivan, Rebecca Shisler Marshall 2023 University of Georgia

A Focused Review Of Multidimensional Well-Being Assessments, Samantha Schonhardt, Stephanie Sullivan, Rebecca Shisler Marshall

Journal of Wellness

Introduction: Interest in the topic of well-being continues to grow and has resulted in the creation of a variety of well-being assessments. However, each assessment often brings its own terminology, theories, definitions, and dimensions. This creates a muddled research base that produces inconsistencies in the field of well-being. Therefore, the aim of this review was to identify assessments that measure multiple dimensions of well-being, catalogue and group the dimensions into categories, and develop definitions for the categories based on the conceptualizations in the literature. In doing so, the dimensionality of well-being portrayed in the literature can be better understood. …


Mindfulness Based Stress Reduction Techniques In Chronic Illness, Anna Celia Gil 2023 Abilene Christian University

Mindfulness Based Stress Reduction Techniques In Chronic Illness, Anna Celia Gil

Electronic Theses and Dissertations

Abstract

Chronic stress and its effect on both physical and mental health have been a topic of increasing interest in the past several decades. There is mounting evidence that recurrent, persistent stress of both a physiologic and psychological nature leads to a dysfunction in the hypothalamic pituitary axis (HPA), the system which helps the body recover and adapt to short term stress. In long term stress, this HPA dysfunction leads to impairment of the immune and neuroendocrine systems resulting in chronic low-grade inflammation. This type of chronic inflammation acts as a precursor to several chronic illnesses such as diabetes, hypertension, …


Urban Land-Based Healing: A Northern Intervention Strategy, Nicole Redvers, Melanie Nadeau, Donald Prince 2023 University of North Dakota

Urban Land-Based Healing: A Northern Intervention Strategy, Nicole Redvers, Melanie Nadeau, Donald Prince

Indigenous Health Faculty Publications

Urban Indigenous populations face significant health and social disparities across Canada. With high rates of homelessness and substance abuse, there are often few options for urban Indigenous Peoples to access land-based healing programs despite the increasingly known and appreciated benefits. In May 2018, the first urban land-based healing camp opened in Yellowknife, Northwest Territories, Canada, one of the first to our knowledge in Canada or the United States. This camp may serve as a potential model for an Indigenous-led and Indigenous-based healing camp in an urban setting. We seek to present preliminary outcome data from the healing camp in a …


Mommy, Me, And We: Why Black Mothers Have Turned To Doulas, Janessa Harris 2023 University of Georgia

Mommy, Me, And We: Why Black Mothers Have Turned To Doulas, Janessa Harris

Crossings: Swarthmore Undergraduate Feminist Research Journal

Maternal mortality mates have disproportionately affected black mothers for far too long due to the lack of value that black bodies hold in medical spaces. Because of this concerns voiced by black people are often disregarded and ignored until the very last minute. But what if this was changed? This paper will focus on how black mothers have worked against Western medical systems that silence our voices, but instead turn to doulas who work to make these mothers feel seen, heard, and cared for. Through this, we make birthing a careful and collective effort to turn Mommy&Me to Mommy&We.


Herbal Medicine Use In Costa Rica: A Case Study Examining Herbal Medicine’S Utilization And Cultural Significance, Jules Schlicting-Bader 2023 Augsburg University

Herbal Medicine Use In Costa Rica: A Case Study Examining Herbal Medicine’S Utilization And Cultural Significance, Jules Schlicting-Bader

Theses and Graduate Projects

Introduction: Herbal medicine has been widely used in the past and present, as it is deeply rooted in many cultures' histories. Literature Review: Herbal medicines are used for health maintenance and treatment in Costa Rica. The country's rich natural environment, accessibility, and tradition led to prominent herbal medicine use. Annona muricata (Soursop), Uncaria tomentosa (Cat's Claw), Mikania species (Guaco), and Neurolaena lobata (Gavilana) have commonly been used in Central American medications and have diverse indications based on their plant parts.

Case Study: A discussion with an herbalist, founder, and citizen of Longo Mai, a community in southern Costa Rica, was …


Mental Health Problems Among Elementary School Students Mandated To E-Learning: A Covid-19 Rapid Review Caveatmandated To E-Learning: A Covid-19 Rapid Review Caveat, Renee M. D'amore, Angelina N. Halpern, Lauren R. Reed, Kevin M. Gorey 2023 University of Windsor

Mental Health Problems Among Elementary School Students Mandated To E-Learning: A Covid-19 Rapid Review Caveatmandated To E-Learning: A Covid-19 Rapid Review Caveat, Renee M. D'Amore, Angelina N. Halpern, Lauren R. Reed, Kevin M. Gorey

Social Work Publications

Extended lockdowns during the COVID-19 pandemic mandated millions of students worldwide to e- learning and by default made many of their parents proxy homeschool teachers. Preliminary anecdotal, journalistic and qualitative evidence suggested that elementary school children and their parents were probably most vulnerable to this stressor and most likely to experience mental health problems because of it. We responded with a rapid review of 15 online surveys to estimate the magnitude of such risks and their predictors between 2020 and 2021. The pooled relative risk of mental health problems among school children and their parents was substantial (RR = 1.97). …


Bibliography, Mary P. Bennett 2023 Western Kentucky University

Bibliography, Mary P. Bennett

Faculty/Staff Personal Papers

Bibliography of publications by Mary Bennett.


Women’S Voices From History: Gond Rani Durgawati And Rani Lakshmibhai, Nandini Sengupta, Moupia Basu 2023 Loyola Marymount University and Loyola Law School

Women’S Voices From History: Gond Rani Durgawati And Rani Lakshmibhai, Nandini Sengupta, Moupia Basu

Monsoon: South Asian Studies Association Journal

Two strong women are compared and contrasted in this article. Gond Rani Durgawati (1524-1564) led a resistance movement in Jabalpur against the Mughal rule of Akbar. Rani Lakshmibai (1828-1858) organized the people of Jhansi against Sir Hugh Rose, an officer defending the interests of the British East India Company. Both women continue to be remembered for their bravery and their loyalty to the people they ruled.


An Examination Of Gandhian Economic And Political Thought And Its Relevance To The Empowerment Of Women, Purnima Mehta Bhatt 2023 Hood College

An Examination Of Gandhian Economic And Political Thought And Its Relevance To The Empowerment Of Women, Purnima Mehta Bhatt

Monsoon: South Asian Studies Association Journal

Mahatma Gandhi (1869-1948) sought to alleviate poverty and empower women. His commitment to nonviolence and the economic ideal of “small is beautiful” continue to inspire grassroots movements around the globe. This article discusses the Chipko movement of northern India, the protection of rain forests in Kerala’s Silent Valley, the Self Employed Women’s Association (SEWA), and Medha Patkar’s valiant though ultimately futile attempt to save the Narmada River from a massive government damming project. The ongoing legacy of these movements can be found in AWAG, the Ahmedabad Women’s Action Group and Women’s Shanti Sena (Peace Force).


Identites Of Women In Indian Art And History, Nalini Rao 2023 Soka University

Identites Of Women In Indian Art And History, Nalini Rao

Monsoon: South Asian Studies Association Journal

The stereotypical image of Indian women portrayed in the art of stone sculpture is often interpreted as images of beauty that are sensuous, religious as well depict social life. There are historical reasons for depicting her as such. This paper inquires into the changing depiction and social forces that influenced feminine imagery. This paper examines the portrayal of beauty through idealization of female body which has evolved over the centuries in India. It also aims to understand their changing status and explores issues of feminine identity, status, and empowerment largely in ancient and medieval India. It also provides a brief …


Constructing Jain Goddess Padmavātī In Gujarati Literature, Venu Mehta 2023 Loyola Marymount University and Loyola Law School

Constructing Jain Goddess Padmavātī In Gujarati Literature, Venu Mehta

Monsoon: South Asian Studies Association Journal

Worship of the goddess Padmāvatī emerged more than a thousand years ago. This article explores three songs about her in Gujarati by Paṇḍit Vīrvijayajī (1773-1852). By analyzing the style and form of his work, one learns a great deal about devotional liturgies that commemorate goddess Padmāvatī’s protection of the Jina Pārśvanātha and, in turn, his protection of her.


Utilizing The Zebrafish Species, Danio Rerio, To Assess The Effect Of Acute Treatment With St. John’S Wort Supplements On Anxiety As Measured By The Novel Dive Tank Test, Sebastian Woodson, Lori McGrew Dr. 2023 Lincoln Memorial University

Utilizing The Zebrafish Species, Danio Rerio, To Assess The Effect Of Acute Treatment With St. John’S Wort Supplements On Anxiety As Measured By The Novel Dive Tank Test, Sebastian Woodson, Lori Mcgrew Dr.

Research Projects

Background: The zebrafish species, Danio rerio, is a widely utilized model organism with well-characterized behaviors including anxiety-like behavior when placed into a novel environment. In addition, the fish can be treated with substances by immersion.

St. John’s Wort has been suggested as a plant-based treatment for depression and anxiety because it contains compounds that inhibit the serotonin transporter (SERT) among other effects. A number of St. John’s Wort supplements are commercially available.

The National Institute of Mental Health (NIMH) estimates that about 19% of US adults suffer an anxiety disorder each year and about 31% will experience an anxiety disorder …


Effects Of A Residential Lifestyle Intervention Program On Selected Lipid Measures And Nutritional Choices, Delores M. Rugless 2023 Southern Adventist University

Effects Of A Residential Lifestyle Intervention Program On Selected Lipid Measures And Nutritional Choices, Delores M. Rugless

DNP Research Projects

Abstract

Objective: Cardiovascular disease has been the leading cause of death since the early 1920s. As with other chronic diseases, cardiovascular disease is primarily influenced by behaviors and the environment, with poor nutrition being a major contributing factor. Despite knowing the importance of lifestyle modification to manage cardiovascular disease effectively, many individuals have difficulty adhering to lifestyle modification principles. Residential lifestyle modification centers provide the education and support necessary to assist individuals with implementing behavioral changes. This DNP project aimed to demonstrate the value of diet modification implemented at a residential lifestyle center to decrease specific cardiovascular risk factors. Method: …


Academic Stress And Anxiety In Nursing Students: An Aerobic Exercise Intervention, Mariko Danielle Aka 2023 Southern Adventist University

Academic Stress And Anxiety In Nursing Students: An Aerobic Exercise Intervention, Mariko Danielle Aka

DNP Research Projects

Abstract

Background: The demands of rigorous nursing education programs often cause students to experience high levels of stress and anxiety during their schooling. Moderate to high academic stress and anxiety levels impact nursing students around the world. This is significant as academic stress and anxiety contribute to decreased academic success, program completion, and student health.

Local Problem: Students at Kettering College and Southern Adventist University were found to have moderate academic stress and anxiety using the SNSI and GAD-7.

Intervention: Participants (N = 24) engaged in a 4-week aerobic-exercise intervention. They were required to complete a minimum of 80 …


Thirty-Second Mindful Body Scan Meditation For Bedside Nurses, Shruti Balwalli-Udyawer 2023 Walden University

Thirty-Second Mindful Body Scan Meditation For Bedside Nurses, Shruti Balwalli-Udyawer

Walden Dissertations and Doctoral Studies

Compassion fatigue, or secondary traumatic stress, is a state of physical and mental exhaustion caused by an inability to cope with the everyday environment that reduces the ability of the nurse to provide high-quality health care to a patient. The purpose of this staff education project, guided by Selye’s general adaption syndrome , was a 6-week, 30-second mindfulness exercise program to promote stress reduction for cardiac step-down and medical-surgical nurses. In this quantitative, pre- and posttest study, the Perceived Stress Scale was completed by a sample of 24 nurses who met the inclusion criteria. The practice focused whether educating nurses …


Chronic Atopic Dermatitis: Symptom Management Using Moisturizers Among Asian American Pediatrics, Ethan J. Brillantes 2023 Dominican University of California

Chronic Atopic Dermatitis: Symptom Management Using Moisturizers Among Asian American Pediatrics, Ethan J. Brillantes

Nursing | Student Research Posters

Background: Atopic Dermatitis (AD), also commonly known as eczema, affects 31.6 million (10%) of the United States Population, with 13% being Asian American or Pacific Islander. A cure is not present for AD; however, the best way to treat AD is with symptom management. While there are many pharmacological treatments that aid with symptom management such as topical or oral corticosteroids, there are also non pharmacological treatments such as moisturizers that can aid with symptom relief of AD as well. Objective: The literature review explores moisturizer use and other non pharmacological methods for symptom management of AD and provides understanding …


Prosaas And Neurodegenerative Diseases, Cydney Battle 2023 Old Dominion University

Prosaas And Neurodegenerative Diseases, Cydney Battle

OUR Journal: ODU Undergraduate Research Journal

Neurodegenerative diseases such as Alzheimer’s disease, prion diseases, Huntington’s disease, and Parkinson’s disease undeniably wreak havoc on the system of the body. The catastrophic effects of neurodegenerative diseases are felt by the reality of being incurable and the resulting effect of the progressive degeneration of the individual’s physical and mental stature. Through continuous research, experimentation, and an understanding of how neurodegenerative diseases develop and function, scientific tactics against the development and progression of these diseases will be uncovered. The abnormal aggregation of proteins is largely attributed to the development of neurodegenerative diseases. In the instance of abnormal protein aggregation, the …


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