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Socio-Environmental Factors Associated With Pubertal Development In Female Adolescents: The Role Of Prepubertal Tobacco And Alcohol Use, Peck, B Mitchell Peck, Valerie J. Skaggs, Miyuki Fukushima, Howard B. Kaplan

Sociology & Criminology Faculty Publications

This cross-sectional study of 3,106 female adolescents, aged 11–21 years, evaluated the association between prepubertal alcohol and tobacco use and the onset of puberty. Ages at initial breast development, body hair growth, and menarche were self-reported. Prepubertal alcohol and tobacco use were defined as the age at first use before the age of pubertal development and accompanied by regular use. Hazard ratios (HR) and 95% confidence intervals (CI) were calculated using Cox proportional hazard models. Logistic regression was used to estimate the association between substance use and delayed puberty, defined as lack of breast development by the age of 13 …