Gerontology Commons^™

Impact Of Baseline Cognition On Dual-Task Performance: Tracking Verbal Accuracy And Fluency In Adults At Risk For Alzheimer’S Disease, Rebecca Nicole Frederichs

Graduate Theses and Dissertations

Alzheimer’s Disease (AD) is increasing in prevalence as life expectancy continues to rise, highlighting the need for sensitive measures to detect early cognitive changes. This study examined the effects of baseline cognitive status on dual-task performance over time, in terms of dual-task cost, verbal fluency, and verbal accuracy in older adults at risk for AD. This study utilized a quantitative secondary analysis of the longitudinal dataset, the Digital, Cognitive, Multi-Domain Alzheimer Risk Velocity (DC-MARVel) study (Gray et al., 2022). Participants were categorized into low, medium, or high cognitive tertiles based on baseline Repeatable Battery for the Assessment of Neuropsychological Status …

More Schooling Can Delay The Onset Of Dementia Later In Life, Vikesh Amin, Jere R. Behrman, Jason M. Fletcher, Carlos A. Flores, Alfonso Flores-Lagunes, Iliana Kohler, Hans-Peter Kohler, Shana D. Stites

Employment Research Newsletter

No abstract provided.

Does Schooling Improve Cognitive Abilities At Older Ages? Causal Evidence From Nonparametric Bounds, Vikesh Amin, Jere R. Behrman, Jason M. Fletcher, Carlos A. Flores, Alfonso Flores-Lagunes, Hans-Peter Kohler

Upjohn Institute Working Papers

We revisit much-investigated relationships between schooling and health, focusing on schooling impacts on cognitive abilities at older ages using the Harmonized Cognition Assessment Protocol in the Health & Retirement Study (HRS) and a bounding approach that requires relatively weak assumptions. Our estimated upper bounds on the population average effects indicate potentially large causal effects of increasing schooling from primary to secondary; yet, these upper bounds are smaller than many estimates from the literature on causal schooling impacts on cognition using compulsory-schooling laws. We also cannot rule out small and null effects at this margin. We do, however, find evidence for …

More Schooling Can Delay The Onset Of Dementia Later In Life, Vikesh Amin, Jere R. Behrman, Jason M. Fletcher, Carlos A. Flores, Alfonso Flores-Lagunes, Iliana Kohler, Hans-Peter Kohler, Shana D. Stites

Upjohn Institute Policy and Research Briefs

No abstract provided.

Driving Habits, Cognition, And Health-Related Quality Of Life In Middle-Aged And Older Adults With Hiv, Josiah J. Robinson, Tess Walker, Cierra Hopkins, Brittany Bradley, Peggy Mckie, Jennifer S. Frank, Caitlin N. Pope, Pariya L. Fazeli, David E. Vance

Graduate Center for Gerontology Faculty Publications

Cognitive impairment is known to increase with aging in people living with HIV (PLWH). Impairment in cognitive domains required for safe driving may put PLWH at risk for poor driving outcomes, decreased mobility, and health-related quality of life (HRQoL). This study described the driving behaviors of middle-aged and older PLWH and examined correlations between driving behaviors and cognitive functioning (Aim 1), and driving behaviors and HRQoL domains (Aim 2). A sample of 260 PLWH ages 40 and older completed a comprehensive assessment including a battery of cognitive tests, an HRQoL measure, and a measure of self-reported driving habits. Associations between …

Age-Related Differences In Cognition And Affect At Work : The Impact Of Mindfulness, Sara Michelle Stevens

Legacy Theses & Dissertations (2009 - 2024)

The present research examined job-related affective and cognitive processes across ages, and the role of trait mindfulness as a mechanism that influences the strength of these relationships. Specifically, job-related affective well-being, job satisfaction, and fluid intelligence were investigated as they relate to dynamics of aging. Participants on Amazon’s Mechanical Turk (N = 174) completed a two-time longitudinal survey separating individual difference tests of trait mindfulness and fluid intelligence at Time 1 from self-report assessments of job satisfaction and job-related affective well-being at Time 2. Overall, the results from this study provide strong evidence that age and mindfulness both play an …

Insomnia And Mild Cognitive Impairment, Ronald C. Hamdy, Amber Kinser, Kara Dickerson, C Kendall-Wilson, Audrey Depelteau, Rebecca Copeland, Kathleen Whalen

ETSU Faculty Works

Insomnia is a common problem in older people, especially in patients with mild cognitive impairment (MCI) whose circadian rhythm is often compromised. Insomnia exerts such a toll on caregivers that it is frequently the primary reason for seeking to institutionalize their loved ones. Three different types of insomnia are recognized: sleep-onset or initial insomnia, sleep maintenance or middle insomnia, and early morning awakening or late insomnia. Nocturnal hypoglycemia, as a cause of middle insomnia, is the main focus of this case study. Other types of insomnia are also briefly reviewed. The management of insomnia is then discussed including sleep hygiene, …

Visual Hallucinations And Paranoid Delusions, Ronald C. Hamdy, Amber Kinser, Tracey Kendall-Wilson, Audrey Depelteau, Rebecca Copeland, Kathleen Whalen, J. Culp

ETSU Faculty Works

Visual well-formed hallucinations, fluctuations in the level of cognition, and alertness and extrapyramidal signs are core features of dementia with Lewy bodies. Some patients realize that what they are seeing or hearing are just hallucinations and learn to accept them. Others, however experience these hallucinations as quite real and cannot be dissuaded from the firm belief that they are. In fact, efforts to dissuade them often serve only to confirm the often associated paranoid delusions and this may lead to a catastrophic ending. Hence, it is best not to contradict the patient. Instead, attempts should be made to distract the …

Driving And Patients With Dementia, Ronald C. Hamdy, Amber Kinser, Tracey Kendall-Wilson, Audrey Depelteau, K. Whalen, J. Culp

ETSU Faculty Works

Driving is a symbol of autonomy and independence, eagerly awaited during adolescence, cherished during adulthood and reluctantly rescinded during old age. It is nevertheless an individual’s privilege, not right, especially as driving may affect other drivers and pedestrians on the road. It is therefore not only the individual patient who is at stake but essentially the entire community. In this case scenario, we describe the situation that arose when a patient with multi-infarct dementia wanted to go for a drive and his son and grandson tried to convince him that he could no longer drive. What went wrong in the …

Effects Of Long-Term Participation In Tennis On Cognitive Function In Elderly Individuals, Scott Culpin

Theses: Doctorates and Masters

Many studies have reported the relationship between exercise and cognition with conflicting results. This may be due to differences in intervention durations, session lengths, intensities, and type of exercise. It has been suggested that exercises requiring greater cognitive demand such as football, basketball and racquet sports, are protective against cognitive decline, compared to less cognitively demanding exercises such as swimming, cycling and running, however, research concerning exercise types are currently limited. The present study tested the hypothesis that elderly individuals who had been regularly playing tennis more than 10 years, would have greater cognitive function than those who had been …

Predictors Of Cognitive Function Among Cognitively Impaired Older African Americans Living In Congregate Residential Settings, Zyra Daffodil Apugan

Dissertations

The purpose of this secondary data analysis was to identify potential psychosocial predictors of cognition, including social support, depression, and functional activity, among older African Americans, ≥ 65 years, with a diagnosis of Alzheimer’s disease and living in congregate residential settings. Guided by the main effect model of social support, this study used existing data from the National Alzheimer’s Coordinating Center Uniform Data Set, an NIH-funded multicenter study. Results showed that on average, the participants (n=56) were 81.7 years of age with 13.8 years of education. All, but six, were married. Bivariate Pearson correlations indicate a moderately strong negative relationship …

Age Drives Distortion Of Brain Metabolic, Vascular And Cognitive Functions, And The Gut Microbiome, Jared D. Hoffman, Ishita Parikh, Stefan J. Green, George Chlipala, Robert P. Mohney, Mignon Keaton, Bjoern Bauer, Anika M. S. Hartz, Ai-Ling Lin

Sanders-Brown Center on Aging Faculty Publications

Advancing age is the top risk factor for the development of neurodegenerative disorders, including Alzheimer’s disease (AD). However, the contribution of aging processes to AD etiology remains unclear. Emerging evidence shows that reduced brain metabolic and vascular functions occur decades before the onset of cognitive impairments, and these reductions are highly associated with low-grade, chronic inflammation developed in the brain over time. Interestingly, recent findings suggest that the gut microbiota may also play a critical role in modulating immune responses in the brain via the brain-gut axis. In this study, our goal was to identify associations between deleterious changes in …

Patients With Dementia Are Easily Distracted, Ronald C. Hamdy, Amber Kinser, Audrey Depelteau, Tracey Kendall-Wilson, J. V. Lewis, Kathleen Whalen

ETSU Faculty Works

Mild cognitive impairment (MCI) is the middle ground between normal, age-appropriate memory impairment, and dementia. Whereas patients with MCI are able to cope with the memory deficit, those with dementia are not: Their memory impairment and other cognitive deficits are of sufficient magnitude to interfere with the patients’ ability to cope independently with daily activities. In both MCI and dementia, there is evidence of declining cognitive functions from a previously higher level of functioning. In both the conditions, there is also an evidence of dysfunction in one or more cognitive domains. There are two subtypes of MCI depending on whether …

Incremental Validity Of Useful Field Of View Subtests For The Prediction Of Instrumental Activities Of Daily Living, Frederik Aust, Jerri D. Edwards

Aging Studies Faculty Publications

Introduction: The Useful Field of View Test (UFOV®) is a cognitive measure that predicts older adults’ ability to perform a range of everyday activities. However, little is known about the individual contribution of each subtest to these predictions, and the underlying constructs of UFOV performance remain a topic of debate.

Method: We investigated the incremental validity of UFOV subtests for the prediction of Instrumental Activities of Daily Living (IADL) performance in two independent datasets, the SKILL (n = 828) and ACTIVE (n = 2426) studies. We then explored the cognitive and visual abilities assessed by UFOV …

Is The Geriatric Impact Ipad Test A Valid Measurement Of Cognitive Function In Older Adults?, Heather Elise O'Dell

Graduate Theses and Dissertations

The number of older adults will rapidly increase within the next generation (Brookmeyer, Johnson, Ziegler-Graham, & Arrighi, 2007). Alzheimer’s disease risk increases with age, especially after age 60 (NIA, n.d.). Aging leads to a decrease in functional independence, and this side effect is exacerbated by cognitive decline (Johnson, Lui, & Yaffe, 2007). Executive function is a predictor of Alzheimer’s disease onset and progression (Zhang, Han, Verhaeghen, & Nilsson, 2007). The Geriatric ImPACTTM test is a potential new and more convenient testing methods than traditional methods used. The purpose of this research is to validate the Geriatric ImPACTTM test by comparing …

A Life Span Approach To The Relationship Between Cholesterol, Late Onset Alzheimer’S Disease, And Cognitive Functioning Among Older Adults, Brian Downer

Theses and Dissertations--Gerontology

There is evidence that cholesterol presents an important risk factor for Alzheimer’s disease (AD), but the direction of this relationship is modified by age. High cholesterol during midlife and low cholesterol during late life are both associated with an increased risk for AD. This dissertation research engaged a life span approach to study the relationship between cholesterol, AD and cognitive functioning among older adults. The purpose of this research was to determine if trajectories of cholesterol from midlife through late life differ according to AD status and if these trajectories are associated with cognitive functioning during old age.

This research …