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2016

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Full-Text Articles in Family, Life Course, and Society

“Si No Participas, Alguien Ajeno Va A Decidir Por Vos:” Practicas De Autonomia En El Bachillerato Popular De Frente Popular Darío Santillán En Constitución, Buenos Aires / "If You Do Not Participate, Someone Else Will Decide For You:" Practices Of Autonomy In The Popular Baccalaureate Of Frente Popular Darío Santillán In Constitución, Buenos Aires, Sarah Kravinsky Oct 2016

“Si No Participas, Alguien Ajeno Va A Decidir Por Vos:” Practicas De Autonomia En El Bachillerato Popular De Frente Popular Darío Santillán En Constitución, Buenos Aires / "If You Do Not Participate, Someone Else Will Decide For You:" Practices Of Autonomy In The Popular Baccalaureate Of Frente Popular Darío Santillán In Constitución, Buenos Aires, Sarah Kravinsky

Independent Study Project (ISP) Collection

Los reformas neoliberales en Argentina durante las últimas décadas han causado una crisis en el sistema educativo público, los efectos de la cual todavía se sienten más profundamente en el sector de para adultos y jóvenes (EDAJ). Durante este mismo período, nuevos movimientos sociales, como el movimiento piquetero de trabajadores desocupadas, habían surgido para resistir las políticas de neoliberalismo y crear fuentes de educación, salud, y trabajo cuando el educación estado no está hacerlo. La presente investigación toma como su tema las prácticas cotidianas y dilemas de la educación popular como una de estas iniciativas, un bachillerato popular (BP) del …


Pelear Por La Dignidad: La Lucha De Las Mujeres Trabajadoras Sexuales Voluntarias Por Derechos Laborales En Un Clima Estigmatizado Políticamente / To Fight For Dignity: The Fight Of Female Voluntary Sex Workers For Labor Rights In A Politically Stigmatized Climate, Rosalind Jones Oct 2016

Pelear Por La Dignidad: La Lucha De Las Mujeres Trabajadoras Sexuales Voluntarias Por Derechos Laborales En Un Clima Estigmatizado Políticamente / To Fight For Dignity: The Fight Of Female Voluntary Sex Workers For Labor Rights In A Politically Stigmatized Climate, Rosalind Jones

Independent Study Project (ISP) Collection

Argentina is a country with a rich history of social movements and popular mobilization. Currently, the issue of women’s equality is highly prevalent in the national and political dialogue. An area that is frequently referenced as a divide in the feminist movement is sex work. Argentina has adopted a series of laws and regulations that have created an ‘abolitionist’ political atmosphere, outlawing the sexual exploitation of individuals and persecuting ‘pimps’, per se. The politics surrounding sex work, on paper, are meant to eliminate human trafficking rings and lower the amount of victims exploited through trafficking. However, the application of the …


El Rol De Los Supermercados Chinos En La Integración Social De La Población China En Buenos Aires / The Role Of Chinese Supermarkets In The Social Integration Of The Chinese Population In Buenos Aires, Dana Marrero Oct 2016

El Rol De Los Supermercados Chinos En La Integración Social De La Población China En Buenos Aires / The Role Of Chinese Supermarkets In The Social Integration Of The Chinese Population In Buenos Aires, Dana Marrero

Independent Study Project (ISP) Collection

Aunque la inmigración china es algo relativamente nuevo en la historia de Argentina, las personas de aquel país han tenido una presencia fuerte en la sociedad de Buenos Aires, la ciudad Capital. En gran parte, esto es debido al nicho económico en el que muchos de los trabajadores chinos se han concentrado: los supermercados. Los pequeños mercados de barrio manejados por dueños chinos son tan comunes que a menudo los porteños simplemente dicen frases como “voy al chino” para referirse a estos comercios. Y con razón: en el 2011, aproximadamente el 35% de todos los mercados de Argentina pertenecía a …


An Evolution Of Tradition: Understanding The Unintended Effects Of The 1999 Inheritance And Marital Property Law On Intra-Family Relationships In Rwanda., Pete Freeman Oct 2016

An Evolution Of Tradition: Understanding The Unintended Effects Of The 1999 Inheritance And Marital Property Law On Intra-Family Relationships In Rwanda., Pete Freeman

Independent Study Project (ISP) Collection

In the months following the 1994 genocide in Rwanda, a disproportionate number of Rwandan women were left without husbands, homes, family, or property. These losses required women to take on cultural responsibilities hitherto reserved for men. One roadblock to assuming these responsibilities was the legal and cultural right of property ownership reserved exclusively for men. Then in 1999, the Rwandan government enacted legislation which allowed women and girls the rights to family property -- Law/nº 22/99 of 12/11/1999 on Matrimonial Regimes, Liberalities, and Successions. On paper, this Rwandan policy seemed like a step toward gender equality, a watershed moment in …


“Always A Double-Edged Sword”: How Women And Health Care Providers Navigate Issues Of Contraception In Differing Senegalese Communities, Angelina Strohbach Oct 2016

“Always A Double-Edged Sword”: How Women And Health Care Providers Navigate Issues Of Contraception In Differing Senegalese Communities, Angelina Strohbach

Independent Study Project (ISP) Collection

This paper examines how women and health care providers in two distinct Senegalese settings—Dakar and Mouit, a village located within the Gandiol region-- navigate contraception as both a social and medical good. Contraception is an invaluable tool in terms of advancing women’s right to reproductive health, but major discrepancies in its usage exist across a variety of social lines in Senegal, including level of education, marital status, occupation, age, and living in a rural versus urban setting. What socially constructed thought processes and lived experiences contribute to these discrepancies? In a cultural context heavily based upon tradition and Islamic faith, …


Consecuencias De La Dictadura: La Salud Mental Transgeneracional En Hijos De Detenidos Desaparecidos / Consequences Of The Dictatorship: Transgenerational Mental Health In Children Of Disappeared Detainees, Catherine Sillari Oct 2016

Consecuencias De La Dictadura: La Salud Mental Transgeneracional En Hijos De Detenidos Desaparecidos / Consequences Of The Dictatorship: Transgenerational Mental Health In Children Of Disappeared Detainees, Catherine Sillari

Independent Study Project (ISP) Collection

Research Question: What are the trends seen in the mental health of the children of the people who were “disappeared” by the Pinochet dictatorship?

Objectives: The general objective of this study is to look for trends in the mental health of children of disappeared people. The specific objectives are to understand the particular stresses that come with disappearances versus other types of deaths, to gage the general opinion of the government’s system of reparation, and to identify common coping methods.

Background: Between the years of 1973-1990, Chile was under the military dictatorship of Augusto Pinochet. During this time, major …


The Importance Of Nature: An Investigation On How Geography Influences Well-Being, Christina Cobb Oct 2016

The Importance Of Nature: An Investigation On How Geography Influences Well-Being, Christina Cobb

Independent Study Project (ISP) Collection

The objective of this community service project (CSP) was to study how a community’s location, specifically within nature, influences their well-being. I hoped to see how the community’s location, within Chapada Diamantina national park, influences the many ways health is promoted, and how these ways are affected by their location within nature. This project was built upon a review of the literature, which found that there is a theoretical basis for the notion that contact with nature is beneficial, a term deemed Biophilia. There is a robust body of academic research that highlights the health benefits deriving from contact …


Tomando En Cuenta: Perspectivas Sobre Las Tomas Del Movimiento Estudiantil Chileno / Taking Into Consideration: Perspectives On The Tomas Of The Chilean Student Movement, María Navarro-Gutiérrez Oct 2016

Tomando En Cuenta: Perspectivas Sobre Las Tomas Del Movimiento Estudiantil Chileno / Taking Into Consideration: Perspectives On The Tomas Of The Chilean Student Movement, María Navarro-Gutiérrez

Independent Study Project (ISP) Collection

Hoy día, actores en el movimiento estudiantil de Chile utilizan varias formas de protesta para comunicar sus deseos e ideas. Entre ellos, la toma de la escuela chilena, durante la cual los estudiantes “ocupan” a su escuela por un periodo de tiempo, se ha convertido en una de las formas de protesta más comunes y emblemáticas del movimiento. Muchas tomas ofrecen un espacio seguro, fuera de las calles, donde los estudiantes pueden instigar un dialogo entre ellos y la administración sobre sus preocupaciones. Sin embargo, aunque las tomas seguidas producen resultados positivos para ambos lados, acusaciones de la pérdida de …


Sentido De Comunidad: Conectando La Teoría Con La Práctica En El Sector La Mariscal, Quito, Ecuador / Sense Of Community: Connecting Theory With Practice In The Mariscal Sector, Quito, Ecuador, Matthew Sant-Miller Oct 2016

Sentido De Comunidad: Conectando La Teoría Con La Práctica En El Sector La Mariscal, Quito, Ecuador / Sense Of Community: Connecting Theory With Practice In The Mariscal Sector, Quito, Ecuador, Matthew Sant-Miller

Independent Study Project (ISP) Collection

En este ensayo, analizaré las maneras en que la teoría del sentido de comunidad se traduce en la práctica. Para cumplir con este análisis, me enfoco en una organización barrial, Operación Urbana Sostenible (OPUS) – La Mariscal, que se ubica en un barrio al norte de Quito, Ecuador. Después de repasar la literatura académica actual y presentar el marco teórico, proveo información básica de fondo tanto del barrio La Mariscal como de la organización OPUS. Luego, considero la temática de la aplicación de la teoría del sentido de comunidad a través de un análisis de tres temas principales que OPUS …


La Lluvia Y El Océano Oculto: El Estudio Del Unu Cambio Y Su Relación Con Viracocha En Chinchero / The Rain And The Occult Ocean: The Study Of The Change And Its Relationship With Viracocha In Chinchero, Edgar J. Payano Oct 2016

La Lluvia Y El Océano Oculto: El Estudio Del Unu Cambio Y Su Relación Con Viracocha En Chinchero / The Rain And The Occult Ocean: The Study Of The Change And Its Relationship With Viracocha In Chinchero, Edgar J. Payano

Independent Study Project (ISP) Collection

Chinchero es una comunidad pequeña donde tradiciones han permanecido, pero a la misma vez el ambiente se está cambiando rápidamente. Una de las actividades más importante de Chinchero es el cultivo seco. El cultivo seco depende de la temporada de lluvias. Mi investigación se trata del unu cambio porque mezclan fuentes de aguas sagradas para atraer lluvia durante sequias. Chinchero siempre ha sufrido de sequias y el unu cambio es un método de prevención desde los tiempos pre-incaicas. Con pocas fuentes de agua en Chinchero, tienen que buscar y utilizar fuentes sagradas afuera de sus inmediaciones. Al otro lado de …


“Mi Resistencia Me Nutre” Las Vivencias De Mujeres Matagalpinas De Acoso Callejero Y Sus Estrategias De Resistencia / "My Resistance Nourishes Me" The Experiences Of Female Street Killers Of Matagalpinas And Their Strategies Of Resistance, Olivia Linn Oct 2016

“Mi Resistencia Me Nutre” Las Vivencias De Mujeres Matagalpinas De Acoso Callejero Y Sus Estrategias De Resistencia / "My Resistance Nourishes Me" The Experiences Of Female Street Killers Of Matagalpinas And Their Strategies Of Resistance, Olivia Linn

Independent Study Project (ISP) Collection

Según un estudio del Observatorio Contra Acoso Callejero de Matagalpa en 2015, acoso callejero es una experiencia casi universal para las mujeres en Nicaragua—el 96% de las entrevistadas reportaron que lo habían experimentado regularmente. Inmediatamente cuando llegué a Managua, descubrí que no era una excepción, pero la cifra no hizo justicia a lo que experimentaba como violencia descorazonadora. Lo que más me desalentó fue la minimización y normalización con que se encontraron mis expresiones sobre mi frustración. De mi lucha por encontrar estrategias adecuadas de resistencia para proteger mi salud mental y emocional, decidí estudiar las experiencias de acoso callejero …


Shelo Yigamer L’Olam: La Construcción De Identidades Compuestas En La Comunidad Judía De Iquitos, Perú / Shelo Yigamer L'Olam: The Construction Of Composite Identities In The Jewish Community Of Iquitos, Peru, Beatrice Waterhouse Oct 2016

Shelo Yigamer L’Olam: La Construcción De Identidades Compuestas En La Comunidad Judía De Iquitos, Perú / Shelo Yigamer L'Olam: The Construction Of Composite Identities In The Jewish Community Of Iquitos, Peru, Beatrice Waterhouse

Independent Study Project (ISP) Collection

Este informe trata de la comunidad judía en Iquitos, Loreto, Perú, y como compara al marco estándar de la identidad judía como diseñado por Simon Herman (1977) y Altman, Fine, Ritter, Inman, y Howard (2010). A través de observación a primera mano y entrevistas con una muestra de participantes en la comunidad organizada, analiza varias facetas de la identidad judía: etnia, religión, relaciones con la comunidad no-judía, nacionalidad, y sentimientos sobre el Estado de Israel. Este estudio de caso encuentra que la comunidad de Iquitos generalmente sigue ese marco con algunas diferencias claves, especialmente con referencia a la prominencia de …


Continuing Efforts To Alleviate "Orange Pain" An Internship With The Da Nang Association Of Victims Of Agent Orange/Dioxin, Loan Heilner Oct 2016

Continuing Efforts To Alleviate "Orange Pain" An Internship With The Da Nang Association Of Victims Of Agent Orange/Dioxin, Loan Heilner

Independent Study Project (ISP) Collection

This year marked the 55th anniversary of Vietnam’s Agent Orange Disaster. Decades after the end of the war, Vietnamese people are still largely being affected by the remnants of the United States’ Agent Orange herbicide sprays. Dioxin chemical has now been confirmed detrimental to human and environmental well-being, but unfortunately it still remains in high concentrations in certain areas of Vietnam. Dioxin chemical is passed on through genetics to new generations, but one of the leading causes of dioxin-related health defects today are due to environmental residue. In Da Nang, Agent Orange was stored and loaded at the local airbase …


A Road To Somewhere: Changing Trade And The Adaptation To Survive In Humla, Sophie Louaillier Oct 2016

A Road To Somewhere: Changing Trade And The Adaptation To Survive In Humla, Sophie Louaillier

Independent Study Project (ISP) Collection

This paper is an investigation of the changing trade in Humla, one of the most remote regions in Nepal. I particularly focus on the road being built from the village of Hilsa, which lies on the border of China and Nepal, to Simikot, the main town. This road will be accessible by all the villagers who live on the link trail now – the trail they walk on with their animals in order to reach the border site. Trade is especially important in Humla; there are no roads available to get there from the Nepal side, so everything must be …


Dharma Dogs: A Narrative Approach To Understanding The Connection Of Sentience Between Humans And Canines, Anna Caldwell Oct 2016

Dharma Dogs: A Narrative Approach To Understanding The Connection Of Sentience Between Humans And Canines, Anna Caldwell

Independent Study Project (ISP) Collection

India has the highest population of stray dogs in the world1. Dharamsala, a cross-cultural community in the north Indian Himalayan foothills, is home to a number of particularly overweight and happy canines. However, the street dogs of Dharamsala are not an accurate representation of the state of stay dogs across India. This paper explores why this may be through narrative stories about the day-to-day interactions between humans and dogs. The following research addresses religious motives as well as the lack thereof.


Pathways To Positive Change: A People's Perspective Of Healthcare In Humla, Wensday Meyers Berman Oct 2016

Pathways To Positive Change: A People's Perspective Of Healthcare In Humla, Wensday Meyers Berman

Independent Study Project (ISP) Collection

The villagers of Humla have suffered from unreliable health services and unjust indifference from the Nepali government for too long. Many global health initiatives and international NGOs have tried and failed to step in and make an improvement of health within these villages, because they are lacking an understanding of how these villages are run, what villagers prioritize, and how to continue providing reliable, supervised support. Because of the remoteness of the Humla area, it is difficult for allopathic medicine to be sufficiently provided here, and access to emergency medical resources are limited. Global health organizations such as WHO and …


Street Art In Kathmandu As A Tool For Activism And Social Change, Madison Minchin Oct 2016

Street Art In Kathmandu As A Tool For Activism And Social Change, Madison Minchin

Independent Study Project (ISP) Collection

In recent years street art has become a popular platform for activism and social commentary in Kathmandu. Both local Nepalis and visiting foreign artists have transformed the streets of the city into their new canvas for art and changemaking. The effectiveness of this unique intersection of art and activism has narrowly been examined through an academic lens. This research intends to understand the specific intentions of street artists and their art in Kathmandu. The effectiveness of this street art as a platform for social change is measured in this research through qualitative interviews and observational techniques. Analysis of the dynamics …


Making It Work: Supporting Contemporary Artists In Ulaanbaatar, Mongolia, Michael Curran Oct 2016

Making It Work: Supporting Contemporary Artists In Ulaanbaatar, Mongolia, Michael Curran

Independent Study Project (ISP) Collection

Following the country’s political transition to democracy in the 1990s, a generation of Mongolian artists constructed an art movement rooted in the issues of the new society: transitional national identity, corrupt political and economic systems, and a growingly complex relationship with nature. The liberalization of the economy, however, hasn’t nurtured sustainable creative resources or helped artists reach domestic or international markets, pressuring them to find alternative ways to create livelihoods out of their craft. This study considers how emerging multidisciplinary artists sustain themselves through both formal and informal means, and the motivations behind their creative lifestyles.

Central to the study …


Contributions Of Television Use To Beliefs About Fathers And Gendered Family Roles Among First-Time Expectant Parents, Patty X. Kuo, L. Monique Ward Oct 2016

Contributions Of Television Use To Beliefs About Fathers And Gendered Family Roles Among First-Time Expectant Parents, Patty X. Kuo, L. Monique Ward

Department of Child, Youth, and Family Studies: Faculty Publications

TV content has been documented to portray a limited range of gender roles, and to frequently depict fathers as incompetent parents. Accordingly, this study explored whether first-time expectant parents’ beliefs about gendered family roles and the importance of fathers to child development were related to their TV use. Participants were 201 individuals (122 women, 79 men) from across the United States expecting their first biological child in a cohabiting heterosexual relationship. Participants completed an online survey assessing weekly TV exposure, exposure to TV programs featuring fathers, perceived realism of TV, use of TV to learn about the world, and beliefs …


Communication Structures Of Supplemental Voluntary Kin Relationships, Dawn O. Braithwaite, Jenna Stephenson, Julia Moore, Katie Brockhage Oct 2016

Communication Structures Of Supplemental Voluntary Kin Relationships, Dawn O. Braithwaite, Jenna Stephenson, Julia Moore, Katie Brockhage

Department of Communication Studies: Faculty Publications

Although scholars have constructed typologies of voluntary (fictive) kin, few have considered challenges and opportunities of interaction and relationships between biolegal and voluntary kin. This study focused on one type of voluntary kin, supplemental voluntary kin, relationships that often arise because of differing values, underperformed roles, or physical distance from the biolegal family, and wherein relationships are maintained with biolegal and voluntary kin. We examined how these family systems are constructed via interactions in relational triads of “linchpin” persons between biolegal family and voluntary kin. From in-depth interviews with 36 supplemental voluntary kin, we examined themes in the linchpins’ discourse …


Halgash, Rhonda (Fa 907), Manuscripts & Folklife Archives Sep 2016

Halgash, Rhonda (Fa 907), Manuscripts & Folklife Archives

Folklife Archives Finding Aids

Finding aid only for Folklife Archives Project 907 titled: "Wedding Beliefs." Project includes note cards with brief descriptions of beliefs about weddings from Kentucky. Sheets include a brief description, informant's name, and the informant classification.


My Mother Needs Me! Is It Possible To Stay Connected While Being My Own Person? The Object Relations Of The Latina “Dutiful Daughter”, Juliana Martinez Sep 2016

My Mother Needs Me! Is It Possible To Stay Connected While Being My Own Person? The Object Relations Of The Latina “Dutiful Daughter”, Juliana Martinez

Dissertations, Theses, and Capstone Projects

Background: Latinas are culturally expected to be “dutiful daughters” establishing strong attachments and adhering to the traditional values characterized by loyalty, cooperation, respect and interdependence within family members. Conventional Latina mother-daughter bonds, therefore, are expected to be exceptionally close. Healthy mother-daughter closeness can be a valuable source of support while closeness without differentiation from the mother may result in a lack of independence and poor interpersonal and personal growth. Mutuality of autonomy, a dimension of object relations (OR) theory, focuses on the progression of separation – individuation from developmentally normative fused representations in infancy to highly differentiated self-other representations as …


Where Have All The Feminists Gone?: A Mixed-Methods Study Of College Students' Attitudes Toward Gender Equality, Erin Maurer Sep 2016

Where Have All The Feminists Gone?: A Mixed-Methods Study Of College Students' Attitudes Toward Gender Equality, Erin Maurer

Dissertations, Theses, and Capstone Projects

The perceived lack of interest in feminism among “millennials” is a subject of continued debate in sociological literature as well as public discourse. While the U.S. women’s movement of the 1960's and ‘70s can claim some success in reducing educational and professional barriers, legalizing abortion, and transforming conceptions of sex/gender both in academia and in the wider culture, numerous obstacles to gender equality remain. Indeed, the paradox of the second-wave is that it was successful in so many respects that young women and men coming of age today might assume that gender equality is a fait accompli. For scholars and …


Boundaries Of Home And Work: Social Reproduction And Home-Based Workers In Ahmedabad, India, Natascia Boeri Sep 2016

Boundaries Of Home And Work: Social Reproduction And Home-Based Workers In Ahmedabad, India, Natascia Boeri

Dissertations, Theses, and Capstone Projects

This dissertation critically questions the use of women’s labor in international development and global capitalism by examining women’s participation in the informal economy, a significant source of work for women in the Global South. Based on ten months of fieldwork in Ahmedabad, India, this study considers women’s experiences with informality when they participate in home-based work, the production of goods for the market in one’s own home. I ask how women’s place-based activities redefine their roles and positions across three spheres of social life: the family, the economy, and civil society (through their participation in a non-governmental organization, or NGO). …


A Southern Chinese City Through The Eyes Of A British Missionary: Preliminary Analysis Of The Text Of A Historical Travelogue, Sai Deng Sep 2016

A Southern Chinese City Through The Eyes Of A British Missionary: Preliminary Analysis Of The Text Of A Historical Travelogue, Sai Deng

Faculty Scholarship and Creative Works

Walks in the City of Canton is a book written by John Henry Gray of Christ's College, Cambridge who came to China and stayed as a missionary for many years, and it was published in 1875. This project did a preliminary analysis of the text of this book digitized by Google from the Library of Harvard University and uploaded to the Internet Archive. The Voyant generated top 500 words are tagged selectively aiming to find the more popular nouns, adjectives and verbs, and their related topics, sentiments or actions. This analysis is combined with the observations obtained in the translation …


Immunomodulators As Therapeutic Agents In Mitigating The Progression Of Parkinson's Disease, Bethany Grimmig, Josh Morganti, Kevin Nash, Paula C. Bickford Sep 2016

Immunomodulators As Therapeutic Agents In Mitigating The Progression Of Parkinson's Disease, Bethany Grimmig, Josh Morganti, Kevin Nash, Paula C. Bickford

Sanders-Brown Center on Aging Faculty Publications

Parkinson’s disease (PD) is a common neurodegenerative disorder that primarily afflicts the elderly. It is characterized by motor dysfunction due to extensive neuron loss in the substantia nigra pars compacta. There are multiple biological processes that are negatively impacted during the pathogenesis of PD, and are implicated in the cell death in this region. Neuroinflammation is evidently involved in PD pathology and mitigating the inflammatory cascade has been a therapeutic strategy. Age is the number one risk factor for PD and thus needs to be considered in the context of disease pathology. Here, we discuss the role of neuroinflammation within …


Extracellular Vesicle-Associated Aβ Mediates Trans-Neuronal Bioenergetic And Ca2+-Handling Deficits In Alzheimer's Disease Models, Erez Eitan, Emmette R. Hutchison, Krisztina Marosi, James Comotto, Maja Mustapic, Saket M. Nigam, Caitlin Suire, Chinmoyee Maharana, Gregory A. Jicha, Dong Liu, Vasiliki Machairaki, Kenneth W. Witwer, Dimitrios Kapogiannis, Mark P. Mattson Sep 2016

Extracellular Vesicle-Associated Aβ Mediates Trans-Neuronal Bioenergetic And Ca2+-Handling Deficits In Alzheimer's Disease Models, Erez Eitan, Emmette R. Hutchison, Krisztina Marosi, James Comotto, Maja Mustapic, Saket M. Nigam, Caitlin Suire, Chinmoyee Maharana, Gregory A. Jicha, Dong Liu, Vasiliki Machairaki, Kenneth W. Witwer, Dimitrios Kapogiannis, Mark P. Mattson

Sanders-Brown Center on Aging Faculty Publications

Alzheimer’s disease (AD) is an age-related neurodegenerative disorder in which aggregation-prone neurotoxic amyloid β-peptide (Aβ) accumulates in the brain. Extracellular vesicles (EVs), including exosomes, are small 50–150 nm membrane vesicles that have recently been implicated in the prion-like spread of self-aggregating proteins. Here we report that EVs isolated from AD patient cerebrospinal fluid and plasma, from the plasma of two AD mouse models, and from the medium of neural cells expressing familial AD presenilin 1 mutations, destabilize neuronal Ca2+ homeostasis, impair mitochondrial function, and sensitize neurons to excitotoxicity. EVs contain a relatively low amount of Aβ but have an …


Reduced Efficacy Of Anti-AΒ Immunotherapy In A Mouse Model Of Amyloid Deposition And Vascular Cognitive Impairment Comorbidity, Erica M. Weekman, Tiffany L. Sudduth, Carly N. Caverly, Timothy J. Kopper, Oliver W. Phillips, David K. Powell, Donna M. Wilcock Sep 2016

Reduced Efficacy Of Anti-AΒ Immunotherapy In A Mouse Model Of Amyloid Deposition And Vascular Cognitive Impairment Comorbidity, Erica M. Weekman, Tiffany L. Sudduth, Carly N. Caverly, Timothy J. Kopper, Oliver W. Phillips, David K. Powell, Donna M. Wilcock

Sanders-Brown Center on Aging Faculty Publications

Vascular cognitive impairment and dementia (VCID) is the second most common form of dementia behind Alzheimer's disease (AD). It is estimated that 40% of AD patients also have some form of VCID. One promising therapeutic for AD is anti-Aβ immunotherapy, which uses antibodies against Aβ to clear it from the brain. While successful in clearing Aβ and improving cognition in mice, anti-Aβ immunotherapy failed to reach primary cognitive outcomes in several different clinical trials. We hypothesized that one potential reason the anti-Aβ immunotherapy clinical trials were unsuccessful was due to this high percentage of VCID …


The Only Way I Was Going To 'Veganize' My Life Was To Immerse Myself, Amanda Osorio Sep 2016

The Only Way I Was Going To 'Veganize' My Life Was To Immerse Myself, Amanda Osorio

UCF Forum

This summer I made the decision to do something that many Latins often hesitate to attempt: become a vegan.


Prospective And Dyadic Associations Between Expectant Parents’ Prenatal Hormone Changes And Postpartum Parenting Outcomes, Robin S. Edelstein, William J. Chopik, Darby E. Saxbe, Britney M. Wardecker, Amy C. Moors, Onawa P. Labelle Sep 2016

Prospective And Dyadic Associations Between Expectant Parents’ Prenatal Hormone Changes And Postpartum Parenting Outcomes, Robin S. Edelstein, William J. Chopik, Darby E. Saxbe, Britney M. Wardecker, Amy C. Moors, Onawa P. Labelle

Psychology Faculty Articles and Research

During the transition to parenthood, both men and women experience hormone changes that are thought to promote parental care. Yet very few studies have explicitly tested the hypothesis that prenatal hormone changes are associated with postpartum parenting behavior. In a longitudinal study of 27 first-time expectant couples, we assessed whether prenatal hormone changes predicted self and partner-reported parenting outcomes at three months postpartum. Expectant fathers showed prenatal declines in testosterone and estradiol, and larger declines in these hormones predicted larger contributions to household and infant care tasks postpartum. Women whose partners showed larger testosterone declines also reported receiving more support …