Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Arts and Humanities (218)
- Criminology (180)
- Quantitative, Qualitative, Comparative, and Historical Methodologies (160)
- Medicine and Health Sciences (154)
- Education (143)
-
- Psychology (127)
- Community-Based Research (113)
- Gender and Sexuality (105)
- Communication (93)
- Family, Life Course, and Society (93)
- Public Affairs, Public Policy and Public Administration (90)
- Law (86)
- Regional Sociology (85)
- Race and Ethnicity (81)
- Feminist, Gender, and Sexuality Studies (76)
- Mental and Social Health (76)
- Social Statistics (72)
- Place and Environment (64)
- Social Control, Law, Crime, and Deviance (60)
- Educational Sociology (59)
- Critical and Cultural Studies (49)
- Physical Sciences and Mathematics (49)
- Domestic and Intimate Partner Violence (45)
- Public Health (45)
- Social Psychology and Interaction (44)
- Art Therapy (43)
- Business (43)
- Higher Education (42)
- Keyword
-
- Hampton Roads (41)
- Surveys (40)
- Quality of life (38)
- Crime (28)
- Book review (27)
-
- United States (20)
- Virginia (20)
- Intimate partner violence (17)
- Gender (16)
- Police (16)
- Family violence (15)
- Children (14)
- College students (14)
- Juvenile delinquency (11)
- Poverty (10)
- Social capital (10)
- Attitudes (9)
- Identity (9)
- Migration (9)
- Race (9)
- Child abuse (8)
- Community college (8)
- Criminals (8)
- Gaming (8)
- Immigration (8)
- Parents (8)
- Rape (8)
- 02. The State (7)
- African Americans (7)
- Domestic violence (7)
- Publication Year
- Publication
-
- Sociology & Criminal Justice Theses & Dissertations (210)
- Reconstruction: Studies in Contemporary Culture (99)
- Life in Hampton Roads Survey Report (74)
- Sociology & Criminal Justice Faculty Publications (60)
- Psychology Theses & Dissertations (46)
-
- EVMS School of Health Professions Theses & Dissertations (34)
- Theses and Dissertations in Urban Services - Urban Education (26)
- Educational Leadership & Workforce Development Theses & Dissertations (18)
- Psychology Faculty Publications (16)
- Counseling & Human Services Theses & Dissertations (15)
- Graduate Program in International Studies Theses & Dissertations (15)
- School of Public Service Faculty Publications (13)
- Institute for the Humanities Theses (11)
- English Faculty Publications (10)
- Health Services Research Dissertations (10)
- OUR Journal: ODU Undergraduate Research Journal (10)
- STEMPS Faculty Publications (10)
- Communication & Theatre Arts Theses (9)
- Counseling & Human Services Faculty Publications (9)
- EVMS School of Health Professions Master's Level Capstones, Projects and Papers (9)
- Human Movement Studies & Special Education Theses & Dissertations (9)
- Theses and Dissertations in Urban Services - Urban Management (9)
- Community & Environmental Health Faculty Publications (8)
- Educational Leadership & Workforce Development Faculty Publications (8)
- English Theses & Dissertations (8)
- School of Public Service Theses & Dissertations (8)
- Teaching & Learning Faculty Publications (8)
- VMASC Publications (8)
- Teaching & Learning Theses & Dissertations (7)
- Cybersecurity Undergraduate Research Showcase (5)
- Publication Type
- File Type
Articles 571 - 600 of 902
Full-Text Articles in Sociology
Effect Of Household Structure On Family-Friendly Benefit Utilization: Implications For Organizational Attraction And Workplace Withdrawal Behaviors Of Federal Government Employees, Sharyn J. Aufenanger
Effect Of Household Structure On Family-Friendly Benefit Utilization: Implications For Organizational Attraction And Workplace Withdrawal Behaviors Of Federal Government Employees, Sharyn J. Aufenanger
Psychology Theses & Dissertations
This study examined the effect of household structure on utilization of family-friendly benefits in organizations, as well as the impact that family-friendly benefit utilization has on organizational attraction and workplace withdrawal behaviors among Federal government employees with children. Results showed that alternative work arrangements (e.g., compressed and flexible schedules) were popular among all employees who have children. Family-friendly benefit utilization rates were highest among single parent employees and lowest among traditional family employees. Single parent employees were more likely to use flexible schedules, part-time, compressed schedules, telework, and sick and annual leave. Dual income employees were more likely to use …
Generals In Three-Piece Suits—Contractors In Camouflage: A Critical Assessment Of Contractors In Iraq, Wyman E. Shuler Iii
Generals In Three-Piece Suits—Contractors In Camouflage: A Critical Assessment Of Contractors In Iraq, Wyman E. Shuler Iii
Graduate Program in International Studies Theses & Dissertations
Contractors compose part of the total force for U.S. warfare capability in Iraq.
Some augment U.S. warfare capability; others do not. Some of the contractors are controlled by the military; others are controlled by civilian (nonmilitary/political) government agencies. The problem: Who are the contractors and how has the nature of government oversight and control over contractors determined whether contractor contributions augment or diminish U.S. warfare capability in the Iraq War?
Argument: It is the degree of government control over contractors that determines whether the contractors' contributions have a positive or negative impact on warfare capability. Ultimately the findings support …
Abuse Behind The Badge Intimate Partner Violence And Child Abuse In Police Families, Denicia M. Veroza
Abuse Behind The Badge Intimate Partner Violence And Child Abuse In Police Families, Denicia M. Veroza
Sociology & Criminal Justice Theses & Dissertations
This study analyzes the factors that may contribute to intimate partner violence and child abuse among police officers' families. Secondary data was obtained from the National Institute of Justice Data Resources Program, "Police Stress and Domestic Violence in Police Families in Baltimore, Maryland, 1997-1999u (Gershon 2000). Surveys were distributed to 1577 Baltimore Police officers. The sample size for this study was 886, which included only those officers who were married, had live-in partners, or were divorced/separated or widowed. From this sample, it was found that 7.9% of the Baltimore Police officers admitted to committing intimate partner violence and 8.4% admitted …
The Simpsons: A Reflection Of Violence, Theodore S. Huptich
The Simpsons: A Reflection Of Violence, Theodore S. Huptich
Sociology & Criminal Justice Theses & Dissertations
Violence in the media has always been a concern to many people. There have been numerous studies that have reviewed the effect that violent television programming has had on the people that have viewed; most of these studies have shown an increase in aggression in the people that viewed the violent programming. However, there have been very few, if any, studies that have examined the amount and type of violence that exists in television programs. This study uses the television program "The Simpsons", due to its popularity and longevity, to examine the amount and type of violence that exists. This …
Predicting Attitude Toward Sex Education In Public Schools, Sarah A. Gibson
Predicting Attitude Toward Sex Education In Public Schools, Sarah A. Gibson
Sociology & Criminal Justice Theses & Dissertations
According to the National Center for Health Statistics, the teen pregnancy rate rose by 3% between 2005 and 2006, presenting the first increase since 1991. These findings are troubling in light of the consequences of teen pregnancy to teen mothers, their children, and society in general. Many commentators suggest that one method of reducing the rate of teen pregnancies is through sex education programs, particularly in the public school system. However, despite the fact that discussions of sex education in public school have been present since the 1920s, polls indicate that there is still a portion of the public that …
Correlates Of Marital Success A Homogamy Model, Sarah A. Raper
Correlates Of Marital Success A Homogamy Model, Sarah A. Raper
Sociology & Criminal Justice Theses & Dissertations
This paper examines the relationship between five demographic homogamy variables and marital success. Throughout this paper, several questions were examined that seek to give a better understanding of the factors that impact the stability and quality of American marriages. Is homogamy an important issue in modern society, or have cultural advancements in American society made homogamy irrelevant? Do both ascribed and achieved characteristics still impact marital success? Data from wave one of the National Survey of Families and Households was used for the analysis. First, correlations between the heterogamy variables and marital success were evaluated. Next, regression models were used …
Virginia Standards Of Learning: An Analysis Of Sociodemographic Effects On Exam Passing Rates, Anne E. Foster
Virginia Standards Of Learning: An Analysis Of Sociodemographic Effects On Exam Passing Rates, Anne E. Foster
Sociology & Criminal Justice Theses & Dissertations
This study proposed to analyze the effects that sociodemographic variables have on Virginia Standards of Learning (SOL) exam passing rates. By analyzing Census data along with passing rates from the Virginia Department of Education, the researcher determined if the independent variables white, non-white, poverty, female-headed household and foreign born explained variance in the SOL passing rates. By using linear regressions for each independent variable as well as a regression for a combination of the independent variables, the researcher was able to show the amount of variance that was explained. The results confirm that variance was present in each test subject …
Warning: Sex Offenders Need To Be Supervised In The Community, Brian K. Payne, Matthew Demichele
Warning: Sex Offenders Need To Be Supervised In The Community, Brian K. Payne, Matthew Demichele
Sociology & Criminal Justice Faculty Publications
The article explains the need for the training of officers so that they may properly supervise sex offenders returning to a community. It is suggested that officers need to be objective, be informed of laws against sexual offending and aware of common characteristics of sex offenders. It is inferred that a combined effort from different government agencies is needed to be able to effectively supervise sex offenders. Several steps to ensure the safety of the supervisors are also discussed.
Rap Music: Gender Difference In Derogatory Word Use, Elizabeth Monk-Turner, D'Ontae Sylvertooth
Rap Music: Gender Difference In Derogatory Word Use, Elizabeth Monk-Turner, D'Ontae Sylvertooth
Sociology & Criminal Justice Faculty Publications
Much of the literature relating to rap assumes such music contains violent and misogynic lyrics. Before exploring the possible deleterious effects of rap lyrics, it is critical to go back to the source and listen to the music. Our work examines the frequency of six profane words in randomly drawn rap music and how this differs between female and male artists. A content analysis of 180 randomly drawn songs from 18 randomly drawn artists was conducted. We expected that male artists would use more profane words compared to female artists. We also expected more profanity, by both male and female …
The Perspective And Practice Of Leadership By Managers Within The Virginia Department Of Corrections: An Instrumental Case Study, Elizabeth M. Gagnon
The Perspective And Practice Of Leadership By Managers Within The Virginia Department Of Corrections: An Instrumental Case Study, Elizabeth M. Gagnon
School of Public Service Theses & Dissertations
This dissertation explores the extent to which the perspective and practice of leadership by managers in the Virginia Department of Corrections (DOC) reflect the Leadership Perspectives Model (LPM), and the extent to which their perspective varies by level of management. The LPM is a model of leadership that consolidates leadership study into five distinct leadership perspectives that managers use in their understanding and practice of leadership. This study builds upon research in which the a LPM was tested and validated within a sample managers from municipal government agencies (M. R. Fairholm, 2004a, 2004b).
The findings of this study reveal that …
The Effects Of Collective Efficacy And Dissatisfaction With Law Enforcement On Neighborhood Crime Rates, Kelly E. Cobb
The Effects Of Collective Efficacy And Dissatisfaction With Law Enforcement On Neighborhood Crime Rates, Kelly E. Cobb
Sociology & Criminal Justice Theses & Dissertations
The purpose of this thesis was to examine the effects of collective efficacy and dissatisfaction with law enforcement on neighborhood crime rates. A data set was obtained from the Inter-University Consortium for Political and Social Research titled, Project on Human Development in Chicago Neighborhoods: Community Survey 1994-1995 (PHDCN). This is one of the only studies which ask specific questions concerning collective efficacy and dissatisfaction with law enforcement, accompanied with a large, diverse sample. This research is important because it looks at two concepts, collective efficacy and dissatisfaction with law enforcement and their combined effect on neighborhood crime rates; violent …
Intimate Partner Homicide, Karitta A. Page
Intimate Partner Homicide, Karitta A. Page
Sociology & Criminal Justice Theses & Dissertations
Using data collected from the Chicago Women's Health Risk Study (Block 2000), this study looked at female perpetrated intimate partner homicide. The purpose of this study was to identify what factors, if any, differentiate between abused women who kill versus abused women who do not kill their intimate partners. Through conducting this study, several factors such as substance abuse, support networks and severe violence were compared between abused women who kill their intimate partner versus those who were abused women but did not kill. It was found that severe abuse, substance abuse by the abuser and the abused person were …
Psychometric Evaluation Of An Instrument For Assessing Policy Outcomes For Families With Children Who Have Severe Developmental Disabilities: The Beach Center Family Quality Of Life Scale, Joni Taylor Mcfelea
Psychometric Evaluation Of An Instrument For Assessing Policy Outcomes For Families With Children Who Have Severe Developmental Disabilities: The Beach Center Family Quality Of Life Scale, Joni Taylor Mcfelea
Health Services Research Dissertations
The purpose of the study was to evaluate the psychometric properties of the Beach Center Family Quality of Life Scale (BCFQLS) in a sample of families with children who have severe developmental disabilities. The study sought to determine whether or not the scale could be used to measure the quality of life of such families and to differentiate between the quality of life of two family groups—those whose child lives in the family home and those whose child lives outside the family home.
The study used an observational, cross-sectional design and both qualitative and quantitative methods. Self-identified primary caregivers of …
The Depiction Of Alcohol Tobacco And Other Substances In Children's G & Pg-Rated Animated Films Post 2000, Lindsay F. Graham
The Depiction Of Alcohol Tobacco And Other Substances In Children's G & Pg-Rated Animated Films Post 2000, Lindsay F. Graham
Sociology & Criminal Justice Theses & Dissertations
This study will analyze the depiction of alcohol, tobacco, and other substances in G and PG-rated animated films from November 1, 2000 to December 31, 2005. These films will include those released in theaters and video in English, at least 60 minutes in length, and of the animated genre during this five-year window. There is evidence that due to recent societal pressures facing the Motion Picture Association of America and their rating guidelines, the presence of alcohol and tobacco in children's animated Grated films has lessened. These incidents of exposure have since moved up the rating totem pole to receive …
A School Art Therapy Group: Helping Eighth Grade Students Decrease Disruptive Behaviors And Increase Coping Skills Before The Transition To High School, Erin Spier
EVMS School of Health Professions Theses & Dissertations
The transition to high school can be difficult for adolescents, especially those exhibiting disruptive behaviors and poor coping skills. This study was concerned with developing conducting a group art therapy intervention that would help increase coping skills and decrease disruptive behaviors in eighth grade students preparing for the transition to high school. Two girls and four boys from a private school in southeastern Virginia participated in the study after the start of their final semester in eighth grade. The study consisted of 8 sessions conducted on alternating days, twice a week for a four-week period.
During the group art therapy …
A Group Art Therapy Intervention To Increase Self-Efficacy In Battered Women, Sheryl Marie Morrison
A Group Art Therapy Intervention To Increase Self-Efficacy In Battered Women, Sheryl Marie Morrison
EVMS School of Health Professions Theses & Dissertations
Domestic violence is a problem that affects an estimated six million women every year (Berry, 1998). There are many theories that attempt to explain the phenomenon such as, learned helplessness and battered woman syndrome. It is clear that the affects of domestic violence can leave lasting damage in the survivor’s ability to cope and function. One aspect that might be hindered in battered women is self-efficacy. Self-efficacy is the degree to which one believes he or she has the ability to be successful. The Self-Efficacy Scale (SES) created by Sherer, et al. (1982) was used to assess the clients’ self-efficacy. …
Mandala As A Measure Of Change With Adult Residents Of A Homeless Shelter, Mary W. Cochran
Mandala As A Measure Of Change With Adult Residents Of A Homeless Shelter, Mary W. Cochran
EVMS School of Health Professions Theses & Dissertations
Homelessness in the United States is a problem that continues to be addressed at the local, state, and federal levels. Diverse solutions to the problem of homelessness include emergency shelters, transitional shelters, and long-term housing. Shelters for families have become a common shelter type, offering diverse programs and types of services. Art therapy with the homeless has concentrated on the aspect of building self-efficacy through the creative process, however, there is limited research concerning the use of art products as a measure of change for the homeless. This study explores the use of mandala drawings to assess changes occurring in …
Review Of Restoring The Connection To The Natural World: Essays On The African American Environmental Imagination, Uwe Küchler
Review Of Restoring The Connection To The Natural World: Essays On The African American Environmental Imagination, Uwe Küchler
Reconstruction: Studies in Contemporary Culture
[First paragraph]
In her introduction to The Ecocriticism Reader from 1995, a landmark in the short and dynamic development of this new field of knowledge, Cheryl Glotfelty anticipated that "Ecocriticism has been predominantly a white movement. It will become a multi-ethnic movement when stronger connections are made between the environment and issues of social justice, and when a diversity of voices are encouraged to contribute to the discussion" (Glotfelty 1996, xxv). The collection of essays reviewed here, published in 2003, fills this gap in ecocritical research. The nine contributors to Sylvia Mayer's edition have critically evaluated various aspects of African …
Camping Out With Ray Bourbon: Female Impersonators And Queer Dread Of Wide-Open Spaces, Don Romesburg
Camping Out With Ray Bourbon: Female Impersonators And Queer Dread Of Wide-Open Spaces, Don Romesburg
Reconstruction: Studies in Contemporary Culture
Mid-twentieth century pansy comedian and female impersonator Ray Bourbon's biography and stage materials suggest a disdain for "wide-open spaces" and queer ambivalences about the rural and the open road as sites of threat and danger. The performer's struggle reflected larger concerns for many queer men, especially traveling professional female impersonators. Often relying on long trips to small towns in order to find work, impersonators were vulnerable to a host of legal and socio-cultural repressions with little recourse. Examining how impersonators negotiated the natural and built environments of small towns and roadsides raises new questions about historical and contemporary understandings of …
Thinking Like A God: Nature Imagery In Advertising, Catherine M. Roach
Thinking Like A God: Nature Imagery In Advertising, Catherine M. Roach
Reconstruction: Studies in Contemporary Culture
This essay examines selected recent imagery from American advertising that evinces a "negative" sense of nature as hostile other - often portrayed as a persecuting and conquered female - and of humans as its/her master. Examples to be examined of nature as this "Bad Mother" include TV commercials, print advertisements, and a comic strip. I argue that these images spring from a fundamental ambivalence toward nature and that they assuage the anxiety aroused by such ambivalence through a fantasy that casts humans as gods. More specifically, I use the medieval Christian scholastic concept of 'aseity' to suggest that these media …
Review Of Castes Of Mind: Colonialism And The Making Of Modern India, By Nicholas B. Dirks, Laxman D. Satya
Review Of Castes Of Mind: Colonialism And The Making Of Modern India, By Nicholas B. Dirks, Laxman D. Satya
Reconstruction: Studies in Contemporary Culture
[First paragraph]
An anthropologist by training, Dirks employs methodologies from a wide range of disciplines to present a critique of British colonialism and its protégé, the caste system. The author lets both the primary and secondary sources speak for themselves to tell the story of how caste under modern colonial conditions came to acquire the status that it had never enjoyed in India's pre-colonial history. The British colonial state made caste the central pillar of Indian civilization and used it to justify its rule by institutionally generating an enormous body of archival data, to prove the authenticity of caste. So …
The Impact Of Privatization On Economic Growth And Income Inequality In Developing Countries, Samuel Adams
The Impact Of Privatization On Economic Growth And Income Inequality In Developing Countries, Samuel Adams
School of Public Service Theses & Dissertations
In the 1960s and 1970s academicians, economists and politicians favored state ownership over private ownership in the production and provision of goods and services. By the end of the 1980s, however, there was a reversal of public policy from state domination of the production and provision of goods and services to private ownership and operation. This was due in part to what the World Bank referred to as "state failure”, which was characterized by inefficient service delivery, unprofitable SOEs, high government debt, and stagnant economic growth rates. Accordingly, privatization caught on in many countries as a policy tool to foster …
Vital Tooth Whitening Effects On Oral Health-Related Quality Of Life In Older Adults, Ann Michelle Poindexter
Vital Tooth Whitening Effects On Oral Health-Related Quality Of Life In Older Adults, Ann Michelle Poindexter
Dental Hygiene Theses & Dissertations
This study determined if vital tooth whitening affects oral health-related quality of life (OHRQOL) in adults ≥50-years old, and if tooth whitening promotes individuals to seek regular professional dental care and participation in social activities. Using a two-group, single blind, randomized, pre-test-post-test design, 62 participants were enrolled. The experimental group used a whitening product twice daily for three weeks, while the control group used no whitening products. Tooth color satisfaction was assessed using the Tooth Color Satisfaction Scale and was correlated with overall oral health-related quality of life. The Oral Health Impact Profile (OHIP), used as the pre-test …
Social Disadvantage And Family Violence: Neighborhood Effects On Attitudes About Intimate Partner Violence And Corporal Punishment, Deeanna M. Button
Social Disadvantage And Family Violence: Neighborhood Effects On Attitudes About Intimate Partner Violence And Corporal Punishment, Deeanna M. Button
Sociology & Criminal Justice Theses & Dissertations
Family violence is widespread and occurs everyday in the United States. The consequences of the various forms of family violence and physical discipline are both immediate and long lasting. As nearly every family is victimized by some type of family violence (Payne and Gainey 2005), it is important that all dynamics of family life be explored. Extending the focus of family violence risk factors to include neighborhood experiences allows for the potential development of different social policies. The purpose of this thesis was to analyze the effects of perceived neighborhood characteristics, in addition to a macro-level measure of crime, on …
The Bachelor Primetime Construction Of Romance, Fairy Tales, And Melodrama, Susan E. Beck
The Bachelor Primetime Construction Of Romance, Fairy Tales, And Melodrama, Susan E. Beck
Institute for the Humanities Theses
This thesis is centered on the reality television program The Bachelor. Presenting itself as a modem day Cinderella story, The Bachelor speaks directly to women's fantasies and their familiarity with fairy tales. In the process, women are molded into convenient and stale stereotypes. Furthermore, the show uses melodrama to create suspense as well as sensational episodes and romantic sentiments to keep the viewer tuned in. Instead of "reality" the show highlights a series of marginalized, sexualized, commodified, and pacified women who place marriage at the epicenter of their selfworth. From Queen for a Day to The Phil Donahue Show …
Who Should Patients Turn To? A Look At Caregivers' Willingness To Perform Various Caregiving Tasks For Patients With Alzheimer's Disease, Melina L. Laroco
Who Should Patients Turn To? A Look At Caregivers' Willingness To Perform Various Caregiving Tasks For Patients With Alzheimer's Disease, Melina L. Laroco
Sociology & Criminal Justice Theses & Dissertations
Research suggests that with baby boomers reaching the age of the retirement, life expectancy rising, and the prevalence of Alzheimer's disease, caregiving roles are almost becoming an established aspect of family obligation (Hoyert 2000). The purpose of this study is to examine and measure the willingness of caregivers to either help with or completely perform the necessary caregiving tasks required by the Alzheimer's.
The data utilized for this study is entitled, "REACH." REACH stands for Resources Enhancing Alzheimer's Caregiver Health. It was gathered by the National Institute of Health and led by the National Institute on Aging. Data were …
College Students' Concerns Regarding Prison Rape, Laura A. Rapp
College Students' Concerns Regarding Prison Rape, Laura A. Rapp
Sociology & Criminal Justice Theses & Dissertations
Abstract unavailable.
Employers Preferences: What Type Of Employers Are Hiring Ex-Offenders?, Gia M. Dyke
Employers Preferences: What Type Of Employers Are Hiring Ex-Offenders?, Gia M. Dyke
Sociology & Criminal Justice Theses & Dissertations
The purpose of this study is to explore the relationship between employers and ex-offenders. The focus here is on which employers have experience in hiring ex-offenders and which do not. More specifically, the central research question of this study is what type of employers' are more inclined to hire what type of offenders? This question is examined by utilizing secondary data collected by the Michigan State Survey Center during spring of 2002. The data were collected for a research project entitled Consequences of a Criminal Record for Employment in Milwaukee, Wisconsin. For the purpose of this study, only data …
Using Peer Mediation As A New Alternative For Conflict Resolution: The Effects On Students' Behaviors And Attitudes, Shanika Anicia Testamark
Using Peer Mediation As A New Alternative For Conflict Resolution: The Effects On Students' Behaviors And Attitudes, Shanika Anicia Testamark
Sociology & Criminal Justice Theses & Dissertations
During the recent years, countless incidents regarding school violence have captured the attention of many, and have disrupted the lives of numerous young students in the United States. In an effort to rebuild a healthier and safer school climate in America schools, many studies have been conducted on peer mediation programs. Peer mediation programs were developed to educate students on how to resolve conflicts constructively.
The purpose of this study was to examine whether the implementation of a peer mediation program called Project S.T.O.P (Students Teaching Options for Peace) could reduce school violence and students' aggressive behaviors and attitudes. To …
Down-Regulation Of Natural Killer Cell Activation In Response To Influenza Virus In Older Adults, Yu Jing
Down-Regulation Of Natural Killer Cell Activation In Response To Influenza Virus In Older Adults, Yu Jing
Theses and Dissertations in Biomedical Sciences
Immune senescence contributes to influenza-associated high mortality and morbidity and reduced vaccine efficacy in elderly people. Type I T cell (Thl)-mediated immunity plays a significant role in Immune responses to influenza infection and vaccination. Natural killer (NK) cells secrete significant amount of IFN-7 , a hallmark Thl cytokine, in response to influenza infection. How aging influences human NK cell IFN-7 production in response to influenza virus has not been well documented. In this study we employed human peripheral blood mononuclear cells (PBMC) and performed intracellular cytokine staining and flow cytometry primarily to investigate how aging influences NK cell activation with …