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Articles 181 - 210 of 388

Full-Text Articles in Pain Management

Analysis Of Zero Balancing Case Studies Through An Occupational Therapy Lens, Deanna Waggy Otr, Msa, Czb, Csla Jan 2022

Analysis Of Zero Balancing Case Studies Through An Occupational Therapy Lens, Deanna Waggy Otr, Msa, Czb, Csla

Journal of Transformative Touch

Does Zero Balancing positively impact occupational performance? This is a question many Occupational Therapists (OTs) ask when discerning if Zero Balancing (ZB) is an evidence-based treatment modality. Case studies from the book Experiencing the Power of Zero Balancing: Case Studies of Journeys to Health and Wholeness (Quarry & King, 2016) were reviewed and compared to the Occupational Therapy domain of practice to show clear evidence that each case study had a positive impact on occupational performance. A comparison chart shows a direct link between the occupational categories and documented evidence of improved occupational performance through practitioner observation and client feedback …


Telehealth Delivery Of Acceptance And Commitment Therapy And Recreational Therapy: Supporting People With Chronic Pain During The Covid-19 Pandemic, Grace L. Roy Jan 2022

Telehealth Delivery Of Acceptance And Commitment Therapy And Recreational Therapy: Supporting People With Chronic Pain During The Covid-19 Pandemic, Grace L. Roy

Honors Theses and Capstones

Chronic pain is a significant public health problem that requires person-centered and comprehensive care to address the many socioecological factors that contribute to pain. Within the context of the COVID-19 pandemic, telehealth options for chronic pain management can help more people access the care that they need. The purpose of the current pilot study was to investigate the efficacy and feasibility of delivering a 6-week Acceptance and Commitment Therapy (ACT) and recreational therapy intervention via telehealth for a group of seven participants with chronic pain. It was found that TeleACT-RT was associated with positive behavioral outcomes including increased psychological flexibility, …


Wound-Dwelling: Empowerment Through Masochistic Experiences, Nizlyn Jan 2022

Wound-Dwelling: Empowerment Through Masochistic Experiences, Nizlyn

MFA in Visual Arts Theses

The psychoanalytic concept of the Skin Ego Theory describes the skin as a passage for pain and pleasure to travel through. Remnants of external experiences as well as internal struggles affect the penetrable barrier of the somatic wrapping and leave inscriptions on the flesh. Through my work, I have been exploring the skin’s ability to protect, envelope, and inscribe meaning through my papercuts, oil paintings, and clay sculptures. I procure the marks on my body through kink and BDSM, which then influence the work. Though my bruises may fade with time, my skin becomes tougher. By recontextualizing Skin Ego Theory …


Mindfulness And Pain Regulation: The Role Of Acceptance And Commitment Therapy For Individuals With Chronic Pain, Ariana C. White Jan 2022

Mindfulness And Pain Regulation: The Role Of Acceptance And Commitment Therapy For Individuals With Chronic Pain, Ariana C. White

Honors Theses and Capstones

Chronic pain is a significant and widely prevalent health condition which requires comprehensive care to address the many facets contributing to symptomatology. In 2016, 20% of American adults (about 50 million) reported experiencing chronic pain, of which 7.4% indicated that chronic pain frequently limited their life and participation in activities within the past 3 months (CDC, 2018). As a result, many individuals with chronic pain turn to opioid-based medication for pain relief, but long-term use of opioids actually increases pain sensation (Tobin, 2019). Moreover, opioid medication is unable to target underlying mental health components which emerge as part of chronic …


Perceived Instability, Pain, And Psychological Factors Predict Function And Disability In Individuals With Chronic Ankle Instability, Ashley M.B. Suttmiller, Julie M. Cavallario, Shelby E. Baez, Jessica C. Martinez, Ryan S. Mccann Jan 2022

Perceived Instability, Pain, And Psychological Factors Predict Function And Disability In Individuals With Chronic Ankle Instability, Ashley M.B. Suttmiller, Julie M. Cavallario, Shelby E. Baez, Jessica C. Martinez, Ryan S. Mccann

Rehabilitation Sciences Faculty Publications

Context:

Chronic ankle instability (CAI) is associated with residual instability, pain, decreased function, and increased disablement. Injury-related fear has been associated with CAI, although its relationship to other impairments is unclear. The Fear-Avoidance Model is a theoretical framework hypothesizing a relationship between injury-related fear, chronic pain, pain catastrophizing, and disability. It has been useful in understanding fear's influence in other musculoskeletal conditions but has yet to be studied in those with CAI.

Objective:

To explore relationships between instability, pain catastrophizing, injury-related fear, pain, ankle function, and global disability in individuals with CAI.

Design:

Cross-Sectional Study

Setting:

Anonymous online survey

Patients …


Eye Movement Desensitization And Reprocessing: Standard Versus Pain-Focused Treatment Protocols, Joni Walsh Jan 2022

Eye Movement Desensitization And Reprocessing: Standard Versus Pain-Focused Treatment Protocols, Joni Walsh

Scripps Senior Theses

Typically used as a trauma therapy, Eye Movement Desensitization and Reprocessing (EMDR) may be a promising intervention for chronic pain, given the relationship (and rates of comorbidity) between chronic pain and post-traumatic stress (PTS). The purpose of the proposed study is to investigate how EMDR therapy might best be implemented as an integrated treatment for chronic pain among individuals with post-traumatic stress symptoms. This study will be the first of its kind to directly compare the standard trauma-focused (TF) EMDR treatment to a popular emerging pain-focused (PF) EMDR treatment modification (Grant, 2000). This study will utilize a matched-participants design and …


Pain Interference Across Chronic Pain Populations: Variability And Associated Psychosocial Processes, Stephanie Judge Jan 2022

Pain Interference Across Chronic Pain Populations: Variability And Associated Psychosocial Processes, Stephanie Judge

Theses and Dissertations--Psychology

Chronic pain is one of the most common health complaints, yet the limited effectiveness of existing treatment options suggests that chronic pain is still not fully understood. The goals of this study are to identify and organize well-established and emerging psychosocial factors associated with pain interference, clarify the nature of between- and within-diagnostic group differences in psychosocial and demographic factors associated with pain interference, and identify interactions among diagnostic and psychosocial factors associated with pain interference.

Community-dwelling participants (N = 284) completed a one-time survey which included demographic information, information about pain and diagnosis, and five existing measures that assess …


Mindfulness To Manage Moral Injury: Rationale And Development Of A Live Online 7-Week Group Intervention For Veterans With Moral Injury, Michelle L. Kelley, Megan Strowger, Victoria O. Chentsova, Adrian J. Bravo, Susan A. Gaylord, Elizabeth E. Burgin, Christine Vinci, Kenneth L. Ayers, Erum Agha Jan 2022

Mindfulness To Manage Moral Injury: Rationale And Development Of A Live Online 7-Week Group Intervention For Veterans With Moral Injury, Michelle L. Kelley, Megan Strowger, Victoria O. Chentsova, Adrian J. Bravo, Susan A. Gaylord, Elizabeth E. Burgin, Christine Vinci, Kenneth L. Ayers, Erum Agha

Psychology Faculty Publications

BACKGROUND: Military service puts service members at risk for moral injury. Moral injury is an array of symptoms (e.g., guilt, shame, anger) that develop from events that violate or transgress one's moral code.

OBJECTIVE: We describe adaption of in-person mindfulness training program, Mindfulness to Manage Chronic Pain (MMCP), to address symptoms of moral injury to be delivered live via the web. We discuss how we will assess benchmarks (i.e., recruitment, credibility and acceptability, completion rates, and adherence) of the Mindfulness to Manage Moral Injury (MMMI) program.

METHODS: Aim 1: To develop and then adapt the MMCP program based on …


Pain Management And Telemedicine: A Look At The Covid Experience And Beyond, Jamal Hasoon, Ivan Urits, Omar Viswanath, Alan D Kaye Jan 2022

Pain Management And Telemedicine: A Look At The Covid Experience And Beyond, Jamal Hasoon, Ivan Urits, Omar Viswanath, Alan D Kaye

Faculty, Staff and Student Publications

COVID-19 caused a drastic change in clinical medicine around the globe. In the United States, telemedicine was rapidly adopted on a wide scale to minimize direct patient interaction and to reduce the spread of the COVID-19 virus. Telemedicine also went hand in hand with the rapid movement of working remotely. This has provided several challenges to chronic pain management clinics along with other subspecialties. Telemedicine has also opened opportunities for providing valuable care for patients with significant barriers to healthcare professionals. Given the benefits and downfalls of telemedicine, it is ultimately up to the provider who has an established patient-physician …


Fadu Head And Neck Squamous Cell Carcinoma Induces Hyperexcitability Of Primary Sensory Neurons In An In Vitro Coculture Model, Megan L Uhelski, Aysegul Gorur, Ted Shi, German Corrales, Kim N Du, Yan Li, Moran Amit, Claudio E Tatsui, Laurence D Rhines, Patrick M Dougherty, Juan P Cata Jan 2022

Fadu Head And Neck Squamous Cell Carcinoma Induces Hyperexcitability Of Primary Sensory Neurons In An In Vitro Coculture Model, Megan L Uhelski, Aysegul Gorur, Ted Shi, German Corrales, Kim N Du, Yan Li, Moran Amit, Claudio E Tatsui, Laurence D Rhines, Patrick M Dougherty, Juan P Cata

Faculty, Staff and Student Publications

Introduction: Currently, cancer pain is viewed as a process orchestrated by the release of pronociceptive molecules and the invasion of neural structures, referred to as perineural invasion (PNI). Cancer pain resulting from PNI is well-documented, but the mechanisms leading to peripheral sensitization because of tumor growth are not fully known.

Methods: A retrospective study was used to examine how the use of anti-inflammatory medications affected preoperative pain in patients with oral squamous cell carcinoma cancer. We then used an in vitro coculture model in which dorsal root ganglion (DRG) neurons were incubated together with Fadu human head and neck squamous …


Treatment And Management Of Xiphoidalgia, Nazir Noor, Ariunzaya Amgalan, Neeraj Vij, Kelly Habib, Lekha Anantuni, Daniel An, Hisham Kassem, Antonella Paladini, Giustino Varrassi, Alan D Kaye Jan 2022

Treatment And Management Of Xiphoidalgia, Nazir Noor, Ariunzaya Amgalan, Neeraj Vij, Kelly Habib, Lekha Anantuni, Daniel An, Hisham Kassem, Antonella Paladini, Giustino Varrassi, Alan D Kaye

Faculty, Staff and Student Publications

Xiphodynia is a rare but debilitating condition that can be described as a form of pain on the xiphisternal joint or any related structures that are anchored to the xiphoid process. Although xiphodynia is a musculoskeletal pain in nature, the pain located in the anterior chest can commonly mislead physicians into pursuing other diagnoses such as cardiac diseases. This leads to a prolonged duration of pain before receiving treatment. In the attempt to alleviate pain resulting from this condition, physicians have previously utilized a range of treatment options, including conservative management, injections, or in severe cases, xiphoidectomy. In this review, …


Effect Of Auricular Acupressure On Acute Pain In Nursing Home Residents With Mild Dementia: A Single-Blind, Randomized, Sham-Controlled Study, Jun Jun Zhang, Li Yu, Jun Hui Mei, Hong Xin Wang, Hai Xiang Gao, Ju Fang Fu, Ye Cheng, Lu Lu Gao, Lei Bu, Jian Qiang Yu, Carol Chunfeng Wang, Yu Xiang Li Jan 2022

Effect Of Auricular Acupressure On Acute Pain In Nursing Home Residents With Mild Dementia: A Single-Blind, Randomized, Sham-Controlled Study, Jun Jun Zhang, Li Yu, Jun Hui Mei, Hong Xin Wang, Hai Xiang Gao, Ju Fang Fu, Ye Cheng, Lu Lu Gao, Lei Bu, Jian Qiang Yu, Carol Chunfeng Wang, Yu Xiang Li

Research outputs 2022 to 2026

Introduction. Acute pain is a prevalent problem for dementia residents in nursing homes. A variety of intervention strategies have been applied to address this problem. However, there remains an issue of inadequate pain control. This study aims to explore the analgesic efficacy of auricular acupressure (AA) for dementia residents with acute pain in nursing homes. Methods. A multicenter, single-blind, randomized, and sham-controlled clinical trial was performed in three nursing homes in Yinchuan, China. All of the 206 eligible patients with acute pain were randomly divided into two groups for real AA therapy or sham AA (at sham point stimulation) therapy. …


Sleeping With The Enemy: Examining The Relationship Between Sleep And Pain In Post-9/11 Veterans, John L. Schwartz Jr. Dec 2021

Sleeping With The Enemy: Examining The Relationship Between Sleep And Pain In Post-9/11 Veterans, John L. Schwartz Jr.

Psychology Theses & Dissertations

United States veterans are a diverse group of individuals, yet as a result of their service, they share a unique set of customs, traditions, and values. Post-9/11 veterans are more likely to experience elevated levels of pain and poor sleep quality compared to their civilian counterparts; however, little is known about how beliefs related to veterans’ pain impact their sleep and how levels of pain acceptance influence the sleep-pain association. This study examined relationships between sleep and pain in a sample of 102 post-9/11 veterans. Results support associations between pain and sleep identified in other populations. Positive correlations were found …


The Subcomponents Of Affect Scale (Sas): Validating A Widely Used Affect Scale, Brooke N. Jenkins, Marie P. Cross, Candice Donaldson, Sarah D. Pressman, Michelle A. Fortier, Zeev N. Kain, Sheldon Cohen, Logan T. Martin, George Farkas Nov 2021

The Subcomponents Of Affect Scale (Sas): Validating A Widely Used Affect Scale, Brooke N. Jenkins, Marie P. Cross, Candice Donaldson, Sarah D. Pressman, Michelle A. Fortier, Zeev N. Kain, Sheldon Cohen, Logan T. Martin, George Farkas

Psychology Faculty Articles and Research

Objective

There is a need for a brief affect scale that also encompasses different components of affect relevant for researchers interested in physiological and health outcomes. The Subcomponents of Affect Scale (SAS) meets this need. This 18-item scale has nine positive and nine negative affect items encompassing six subscales (calm, well-being, vigour, depression, anxiety, anger). Previous research using the SAS has demonstrated its predictive validity, but no work has tested its subscale structure or longitudinal validity.

Design

Data from the Common Cold Project in which individuals (N = 610) completed the SAS over the course of seven days were used. …


Shu Altop News Issue #4, Fall, Dr. Susan L. Davis, Rn & Richard J. Henley College Of Nursing Oct 2021

Shu Altop News Issue #4, Fall, Dr. Susan L. Davis, Rn & Richard J. Henley College Of Nursing

News, Magazines and Reports

Updates from the Davis & Henley College of Nursing Sacred Heart University Alternatives to Opioids for Pain Grant.

Alternatives to Opioids for Pain (ALTOP) is a HRSA funded project to help combat the opioid epidemic in Connecticut.

In this issue: • New Roles in Our Team • ANEW HRSA 2021-2022 Awardees • Southwest Community Health Center Chiropractic Care Services • Student Quality Improvement Project • Sacred Heart University Alumni Working at New Solutions Pain Management Clinic.


Black And White Health Disparities: Racial Bias In American Healthcare, Yasmeen Almomani Jul 2021

Black And White Health Disparities: Racial Bias In American Healthcare, Yasmeen Almomani

Bridges: An Undergraduate Journal of Contemporary Connections

This paper explores the historical implications of race in American society that have led to implicit racism in the healthcare system. Racial bias in healthcare against Black people is a factor in the health disparities between Black and white people in America, such as the gap in life expectancy, infant death, and maternal mortality. Black people are more likely to report racial discrimination from healthcare providers, which is a reason for the decreased quality of care received. The past justifications of slavery, the Tuskegee syphilis study, and the medical experimentations on Black women are horrifying but were considered acceptable in …


An Investigation Of Occupational Therapy Utilizing Sensory Modulation To Manage Co-Morbid Chronic Pain And Substance Use In Order To Promote Occupational Performance And Recovery, Claire Ruth Jun 2021

An Investigation Of Occupational Therapy Utilizing Sensory Modulation To Manage Co-Morbid Chronic Pain And Substance Use In Order To Promote Occupational Performance And Recovery, Claire Ruth

Student Capstone Papers

Background: Those with chronic pain have worse drug and alcohol treatment outcomes and higher rates of relapse compared to those without pain or with reduced pain (Ilgen et al., 2020).

Methods: A descriptive study was employed with the aim of determining what are the sensory processing pattens of those with co-morbid chronic pain and in recovery for substance use. All participants completed the Adolescent and Adult Sensory Profile, the Brief Pain Inventory, and the Personal Recovery Outcome Measure (PROM).

Results: From the preliminary findings, individuals with co-morbid chronic pain and substance use may have atypical sensory processing …


Shu Altop News Issue #3, Summer, Dr. Susan L. Davis, Rn & Richard J. Henley College Of Nursing Jun 2021

Shu Altop News Issue #3, Summer, Dr. Susan L. Davis, Rn & Richard J. Henley College Of Nursing

News, Magazines and Reports

Updates from the Davis & Henley College of Nursing Sacred Heart University Alternatives to Opioids for Pain Grant.

Alternatives to Opioids for Pain (ALTOP) is a HRSA funded project to help combat the opioid epidemic in Connecticut.


Post-Operative Pain Management Modalities Employed In Clinical Trials For Adult Patients In Lmic; A Systematic Review, Gauhar Afshan, Robyna Irshad Khan, Aliya Ahmed, Ali Sarfraz Siddiqui, Azhar Rehman, Syed Amir Raza, Rozina Kerai, Khawaja Mustafa May 2021

Post-Operative Pain Management Modalities Employed In Clinical Trials For Adult Patients In Lmic; A Systematic Review, Gauhar Afshan, Robyna Irshad Khan, Aliya Ahmed, Ali Sarfraz Siddiqui, Azhar Rehman, Syed Amir Raza, Rozina Kerai, Khawaja Mustafa

Department of Anaesthesia

Background: Unrelieved postoperative pain afflicts millions each year in low and middle income countries (LMIC). Despite substantial advances in the study of pain, this area remains neglected. Current systematic review was designed to ascertain the types of clinical trials conducted in LMIC on postoperative pain management modalities over the last decade.
Methods: A comprehensive search was performed in June 2019 on PubMed, Cochrane Library, CINAHL Plus, and Web of Science databases to identify relevant trials on the management of postoperative pain in LMIC. Out of 1450 RCTs, 108 studies were reviewed for quality evidence using structured form of critical appraisal …


The Effectiveness Of Art Therapy As A Treatment Modality In Improving Quality Of Life For Adults With Chronic Pain, Kayley Nelson May 2021

The Effectiveness Of Art Therapy As A Treatment Modality In Improving Quality Of Life For Adults With Chronic Pain, Kayley Nelson

Expressive Therapies Capstone Theses

The efficacy of art therapy is explored in the context of improving the quality of life and mental health of individuals experiencing chronic pain. The exploration and examination of previous research on chronic pain and art therapy have led to various interconnected themes that tie together the needs of this population with the healing aspects of this treatment method. Through gathering data on both the negative impact of chronic pain and the healing aspects of art therapy and exploring research on chronic pain art therapy groups already in action, it can be deduced that future research may further illuminate the …


Knowing What We Know: Leveraging Community Knowledge Through Automated Text-Mining, Justin Gardner, Jonathan Tory Toole, Hemant Kalia, Garry Spink Jr., Gordon Broderick May 2021

Knowing What We Know: Leveraging Community Knowledge Through Automated Text-Mining, Justin Gardner, Jonathan Tory Toole, Hemant Kalia, Garry Spink Jr., Gordon Broderick

Advances in Clinical Medical Research and Healthcare Delivery

No abstract provided.


Reiki For Recovery: Incorporating Japanese Health Practices To Increase Contemporary Resiliency In American Health, Leif Peterson May 2021

Reiki For Recovery: Incorporating Japanese Health Practices To Increase Contemporary Resiliency In American Health, Leif Peterson

Master's Projects and Capstones

The Japanese health practice of Reiki attempts to maximize the latent ability of the human system to heal itself. The Reiki system, established over a century ago, combines multiple Asian health traditions, experimenting with practices that maximize the natural processes of the body to perform its own repairs. Reiki encourages healthy behaviors that balance the mind and body, return the human system to a lowered stress level, and allow for an optimal recovery state for the patient. This paper illustrates how this Japanese health-affirming method can be integrated and utilized within existing health and medical practices. An area that is …


The Use Of Mindfulness Meditation To Increase The Efficacy Of Mirror Visual Feedback For Reducing Phantom Limb Pain In Amputees, Nicolas Sebastian Mills May 2021

The Use Of Mindfulness Meditation To Increase The Efficacy Of Mirror Visual Feedback For Reducing Phantom Limb Pain In Amputees, Nicolas Sebastian Mills

Doctoral Dissertations

Phantom limb pain is a chronic pain condition that negatively impacts the lives of over half of amputees, and results in considerable morbidity. Currently, there is no gold standard for treatment for phantom limb pain. However, a frequently used intervention is the use of mirror visual feedback, in which the amputee watches the reflection of the adjacent non-amputated limb move and exercise. In the last few decades, mindfulness-based interventions have been increasingly used with individuals living with different types of chronic pain. This study attempts to discover if the addition of a mindfulness-based intervention, such as guided meditation, will augment …


Emotional And Social Functioning Of Parents Of Youth Presenting For Intensive Interdisciplinary Pain Treatment, Jenny Scheurich May 2021

Emotional And Social Functioning Of Parents Of Youth Presenting For Intensive Interdisciplinary Pain Treatment, Jenny Scheurich

Research Days

Background: Parents of youth with chronic pain experience significant emotional distress and social difficulties, and in turn, their distress impacts the health and functioning of youth with chronic pain. However, few studies have examined the specific emotional and social needs of these parents, and even fewer have tested intervention strategies specifically targeting these needs. Intensive interdisciplinary pain treatment (IIPT) for youth with chronic pain leads to improvement in the youth’s physical and mental health and has been associated with reduced anxiety and depression in parents. IIPT often include treatment modules aimed at parental pain management strategies, such as psychoeducation, parent …


Understanding Illness Encouragement And Pain Acceptance In Pediatric Patients With Abdominal Pain, Scott Wagoner May 2021

Understanding Illness Encouragement And Pain Acceptance In Pediatric Patients With Abdominal Pain, Scott Wagoner

Research Days

Background: Parents can respond to their child’s abdominal pain in a variety of ways, and parental illness encouragement (e.g., spoiling, letting child stay home from school) is known to relate to longer periods of illness. Modeling and reinforcement of the “sick role” has been used to explain these processes. Many pediatric patients with abdominal pain will continue to experience symptoms in adulthood, so having a full understanding of what pain management techniques patients adopt is crucial. This study explored the impact of parental illness encouragement on how patients engage in valued activities (i.e., activity engagement) and prioritize controlling their pain …


Sex As A Moderator In The Relationship Between Post-Operative Pain And Analgesics Administered In Children Undergoing Elective Surgery, Amber M. Osorno, Michelle A. Fortier, Zeev N. Kain, Brooke N. Jenkins May 2021

Sex As A Moderator In The Relationship Between Post-Operative Pain And Analgesics Administered In Children Undergoing Elective Surgery, Amber M. Osorno, Michelle A. Fortier, Zeev N. Kain, Brooke N. Jenkins

Student Scholar Symposium Abstracts and Posters

About 85% of children who undergo elective surgery experience pain post-operatively and many do not receive proper pain management care after discharge. Most parents lack an understanding of proper pain care management using analgesics upon discharge. Research reveals that adults rate girls as more sensitive to pain and that they display a greater amount of pain in a pediatric post-operative environment. In adulthood, women report more sensations of pain and have a higher pain tolerance, which can be attributed to physiological characteristics. Nonetheless, the social differences by which boys and girls experience pain and express their pain cannot be denied. …


Effects Of Sleep On Intrusive Symptoms And Emotional Reactivity In A Laboratory-Based Film Analog Study, Anna Marie Thi Thanh Nguyen May 2021

Effects Of Sleep On Intrusive Symptoms And Emotional Reactivity In A Laboratory-Based Film Analog Study, Anna Marie Thi Thanh Nguyen

Graduate Theses and Dissertations

Posttraumatic stress disorder (PTSD) is characterized by four symptom clusters. Recently, research highlights the need to focus on the impact of intrusive symptoms as a possible risk factor for the development and maintenance of PTSD. Cognitive and sleep models contribute to further understanding of intrusive symptoms. Recent work also highlights disgust as an emotion closely associated with the emergence of posttraumatic stress symptomology following traumatic events. This study used a film eliciting disgust in order to examine the effects of sleep on the intensity of intrusion symptoms and emotion reactivity. The sample consisted of 49 college students randomly assigned to …


Prospective Patient-Reported Symptom Profiles Associated With Pediatric Acute Lymphoblastic Leukemia Relapse, Austin L Brown, Kimberly P Raghubar, Olga A Taylor, Melanie Brooke Bernhardt, Lisa S Kahalley, Wei Pan, Philip J Lupo, Marilyn J Hockenberry, Michael E Scheurer May 2021

Prospective Patient-Reported Symptom Profiles Associated With Pediatric Acute Lymphoblastic Leukemia Relapse, Austin L Brown, Kimberly P Raghubar, Olga A Taylor, Melanie Brooke Bernhardt, Lisa S Kahalley, Wei Pan, Philip J Lupo, Marilyn J Hockenberry, Michael E Scheurer

Faculty, Staff and Students Publications

PURPOSE: Despite improvements in frontline pediatric acute lymphoblastic leukemia (ALL) treatment, relapse remains a concern. Research in adult cancer patients suggests that patient-reported symptoms may predict survival, but the relationship between symptoms and relapse for pediatric ALL has received little attention.

METHODS: Pediatric patients with ALL (age 2-18 years) and/or their primary caregivers completed symptom surveys at the end of induction, start of delayed intensification (DI), start of maintenance cycle 1 (MC1), and start of maintenance cycle 2 (MC2). Symptom clusters for co-occurring fatigue, pain, sleep disruptions, and nausea were defined using latent profile analysis. Hazard ratios (HR) and 95% …


A Systematic Review And Meta-Analysis On The Efficacy Of Repeated Transcranial Direct Current Stimulation For Migraine, Guoshuai Cai, Zhu Xia, Leigh Charvet, Feifei Xiao, Abhishek Datta, X Michelle Androulakis Apr 2021

A Systematic Review And Meta-Analysis On The Efficacy Of Repeated Transcranial Direct Current Stimulation For Migraine, Guoshuai Cai, Zhu Xia, Leigh Charvet, Feifei Xiao, Abhishek Datta, X Michelle Androulakis

Publications and Research

Purpose: Transcranial direct current stimulation (tDCS) may have therapeutic potential in the management of migraine. However, studies to date have yielded conflicting results. We reviewed studies using repeated tDCS for longer than 4 weeks in migraine treatment, and performed meta-analysis on the efficacy of tDCS in migraine.

Methods: In this meta-analysis, we included the common outcome measurements reported across randomized controlled trials (RCTs). Subgroup analysis was performed at different post-treatment endpoints, and with different stimulation intensities and polarities.

Results: Five RCTs were included in the quantitative meta-analysis with a total of 104 migraine patients. We found a significant reduction of …


Experience Of Loss And Resilience In Persons With Chronic Pain, Lauren Abshire Apr 2021

Experience Of Loss And Resilience In Persons With Chronic Pain, Lauren Abshire

Doctor of Psychology (PsyD)

Chronic pain is one of the most common concerns people seek medical treatment for, yet it is historically difficult to treat. The current best evidence practice in chronic pain treatment is through a multidisciplinary team with psychologists implementing cognitive behavioral therapy or acceptance commitment therapy. These approaches are efficacious in decreasing pain-related behaviors and improving mood and quality of life. Resilience has also been shown to mitigate the impact of chronic pain. However, the sense of loss or grief related to the experience of chronic pain has been inadequately explored in the research literature and may be related to poor …