Experimental Analysis of Behavior Commons^™

Assessment Of Sex Differences And Amphetamine On Schedule-Induced Polydipsia, Min Park

All NMU Master's Theses

Amphetamine (AMPH) is one of the most common psychotropic drugs abused in the United States. Its major pharmacological effect is to increase synaptic dopamine levels in the mesolimbic reward pathway, which in turn causes behavioral effects in animals, and subjective effects in humans. These reinforcing properties of AMPH trigger very strong levels of craving the drug, and eventually result in patterns of compulsive use of AMPH. Regarding psychostimulant action, female rats have been reported to be more vulnerable to the reinforcing effects of psychostimulants. In the current study, schedule-induced polydipsia (SIP), an animal model of compulsive behavior, was applied for …