Experimental Analysis of Behavior Commons^™

Dreadds Modulation Of Operant Behavior In Male And Female Hiv-1 Transgenic And F344/N Rats, Jessica Illenberger

Theses and Dissertations

The neurobiological processes which determine the choice between 2 (or more) reinforcers are unidentified despite the remarkable benefits which could result from better understanding or control of such processes. Most prominently, reducing choices to pursue drug over non-drug reinforcers could curtail the development or continuation of drug dependence. Likewise, increasing goal-directed behavior in single-schedule and choice settings may alleviate some of the consequences of apathy, a reduction in goal-directed behavior which can occur with neuropathologies including HIV-associated neurocognitive disorders. Dysregulation of the mesolimbic circuit, connecting the ventral tegmental area to the nucleus accumbens, has been implicated in both drug dependence …

Treatment Of Hiv-1 Associated Neurocognitive Disorders Through Mechanisms Of Neurogenesis With 11-Hour Voluntary Running Wheel Exposure, Alex Steiner

Theses and Dissertations

Individuals with HIV-1 taking combined antiretroviral therapy (cART) live longer with less morbidity associated with the infection. The increase in lifespan has created a critical need for the deterrence of HIV-1 associated neurocognitive disorders (HAND) reported in the aging population. Previous reports indicate that the HIV-1 infection may cause impairment in neurogenesis, leading to many of the cognitive deficits seen. The current paper proposes that exercise, as defined by voluntary wheel running, would be a potent inducer of neurogenesis that results in the neuro-restoration of CNS properties and cognitive functioning. Each animal had free access to 11-hour nocturnal wheel-running seven …

Response Interruption And Redirection (Rird) As A Treatment For Vocal Stereotypy In Children Who Are Dually Diagnosed With Autism And Down Syndrome, Stacy Taylor

Theses and Dissertations

Individuals who are dually diagnosed with Down Syndrome (DS) and autism spectrum disorders (ASD) frequently engage in vocal stereotypy that can interfere with learning, impede socially appropriate behavior, and disrupt others. Response interruption and redirection (RIRD) is an intervention that blocks and redirects stereotypy to reduce behavior. Studies on RIRD, while varied in their overall approach, have overwhelmingly been shown to be effective in clinical settings for children with ASD. There are few studies that have evaluated this procedure in more natural settings and with other diagnoses. Given that ASD is prevalent in those with DS and that stereotypy is …

Online Training To Improve Job Coaches’ Support Of Minimally Verbal And Nonverbal Adults With Autism Spectrum Disorder, Erin Brooker Lozott

Theses and Dissertations

Although a sizeable percentage of individuals with autism spectrum disorder (ASD) are minimally verbal or nonverbal, there is limited research on how to best support these individuals in employment settings. Job coaches working with this population should receive specialized training in evidence-based practices (EBP) for ASD to ensure optimal outcomes. This study describes the development, implementation, and evaluation of an online training program for job coaches focused on a behavior skills training approach supporting the use of augmentative and alternative communication. Twenty-two job coaches completed the study. Pre- and posttraining measures were used to evaluate knowledge, self-efficacy, and belief systems …

Variation In Personality Among Semi-Wild Myanmar Timber Elephants, Sateesh Venkatesh

Theses and Dissertations

This study examines two personality traits: exploration and neophobia, which could influence human-elephant conflicts. Thirty-one semi-wild elephants were tested over two trials using a custom novel puzzle tube containing three tasks and three rewards. Our studies show that elephants do vary significantly between individuals in both exploration and neophobia.

Application Of The “Idisco” Full-Brain Tissue Clearing Method: A View Of Dopamine And Inflammation In The Hiv-1 Transgenic Rat, Kristin Nickole Kirchner

Theses and Dissertations

The iDISCO (immunolabeling-enabled three-dimensional imaging of solvent-cleared organs) method is a quick, inexpensive, and easily adaptable tissue staining and clearing procedure that allows neuroscientists to study a protein of interest in a whole, unaltered tissue sample. While the iDISCO method was initially tested and validated for mice embryos and brains, the current experiment sought to adapt the method for use in the rat using HIV-1 transgenic (Tg) rat brain tissue. Antibodies for tyrosine hydroxylase and Iba-1 were validated in the HIV-1 Tg rat and in F344/N control rats using iDISCO. Confocal images were taken of tyrosine hydroxylase positive neurons in …

The Behavioral And Neural Effects Of Audiovisual Affective Processing, Chuanji Gao

Theses and Dissertations

In everyday life, we receive affective information from a multisensory environment. What we see and what we hear jointly influence how we feel, think and act. Outstanding questions still remain about the essential behavioral and neural mechanism underlying how we combine visual and auditory affective signals. In this dissertation, I report a series of behavioral, EEG and fMRI experiments addressing this question. I found behaviorally there are congruency, visual dominance, and negativity dominance effects. Using ERPs, I showed that these behavioral effects can map onto different time course in audiovisual affective processing. Time-frequency analyses of EEG data showed that there …

Testing For Differential Attention To Features In Evaluative Conditioning, Christine E. Weber

Theses and Dissertations

One eye tracking and one behavioral experiment examined the possible roles of contingency awareness and attention to stimulus features in evaluative conditioning. These experiments tested whether evaluative conditioning altered the saliency of positive and negative features in consumer products (Study 1) and attitudinal responses to ambivalent pictures (Study 2). Based on the conceptual categorization model, pairing of ambivalent conditioned stimuli with liked or disliked unconditioned stimuli was predicted to result in enhanced attention to affectively congruent features. Study 1 tested this prediction by recording eye movements to determine how attention to features and responses to ambivalent stimuli were altered as …

Using Object-Choice Tasks To Investigate Sensory Perception In Sunda Pangolins (Manis Javanica), Joshua Dipaola

Theses and Dissertations

Pangolins are one of the most heavily poached, yet least understood mammals in the world. In this study, we used an object-choice task to assess the ecological relevance and use of sensory information in Sunda pangolin foraging behavior. This is the first controlled experiment on pangolin behavior to our knowledge.

The Maze Of Personality: Latency And Electric Organ Discharge In A Mormyrid Fish, Gnathonemus Petersii Gunther 1862 (Mormyridae, Teleostei), Abbey C. Lipe

Theses and Dissertations

Personality is individual differences in behavior, consistent across contexts. Among Gnathonemus petersii we investigated, we hypothesized that fish could be grouped by: (1) slow/fast maze performance, (2) low/high electric frequencies, (3) correlated latency and frequency. Our first two hypothesis were not supported. Our third hypothesis was partially supported.

Motivational And Physiological Dysregulation Due To Development And Onset Of Obesity Via Melanocortin 4 Receptor +/- Haploinsufficiency, Alex Steiner

Theses and Dissertations

Obesity is one of the leading most health risks around the world, being especially problematic in the United States. A combination of high-fat diets and genetic abnormalities are to blame for the ever-growing number of obese individuals.

Melanocortin 4 receptors are vital for regulating energy expenditure and feeding behaviors; mutations of the receptors have been found to be the leading monogenetic cause of obesity. Using MC4R +/- haploinsufficient rats being fed a range of dietary fat, we investigated the physiological and motivational differences using a locomotor task, an operant task with fixed and progressive ratios, as well as a distraction …

Judging Facial Expressions Of Emotion: Effects Of Gender, Raine Palladino

Theses and Dissertations

This study examined how quickly people recognize happy, neutral or angry emotional expressions on faces that varied in gender presentation and femininity/masculinity of facial features. Facial features influenced judgments of emotion more for women than men. Neutral expressions were more likely seen as angry on a woman’s face.

Inhibition Of Return In Visual Search: Disentangling Overlapping Contributions With Event-Related Potentials, Allison Michelle Pierce

Theses and Dissertations

Inhibition of return (IOR) refers to the finding that responses to previously attended locations are slower than those to previously unattended locations. Despite over 30 years of research on IOR, there is still no consensus in the field regarding what the underlying mechanism of this effect is. Although IOR is traditionally studied within spatial cueing paradigms, this effect is thought to reflect a mechanism that facilitates efficient visual search. The following studies explored the hypothesis that multiple processes contribute to the IOR effect in visual search and examined whether these are the same processes that result in IOR in cueing …

Building A Statistical Model Of The Drivers Of Self-Presentation, Kathleen Jocoy

Theses and Dissertations

The attempt to maintain a consistently positive public image is known as self-presentation; however, the structure of self-presentation has not been adequately explored. This paper aimed to identify a theory-based model for self-presentation by examining the relationship between personality traits and utilization of self-presentational behaviors. A review of the literature suggested self-presentation would be best modeled with a second order two-factor model with second order factors of Evaluation and Response. The second order factor of Evaluation is expected to explain the first order factors Perceived Anonymity, Sociability, and Communality while the second order factor of response is expected to explain …

Behavioral And Voltammetric Analysis Of Chronic Escitalopram Treatment To The Hiv-1 Transgenic Rat: Implications For Comorbid Hiv-1 And Clinical Depression, Adam R. Denton

Theses and Dissertations

HIV-1 infection is a serious condition affecting approximately 37 million individuals. Between 30% and 60% of seropositive individuals will develop symptoms of clinical depression. These individuals are five times more likely to commit suicide than non-seropositive clinically depressed patients. Dysfunction in serotonergic and dopaminergic transmission has consistently been implicated in the pathogenesis of depression. Specifically, dysfunction in the prefrontal cortex and in the nucleus accumbens core region have been shown to be underlying factors in the trajectory of depression. Given these underlying neurological features, the present research employed behavioral testing and electrochemical recording in an attempt to elucidate the therapeutic …

Contextually Modulated Avoidance Behavior In Rats Post-Pavlovian Extinction, Lauren Branigan

Theses and Dissertations

The following study sought to examine the psychological substrates of renewal (e.g.., context dependent extinction processes) for conditioned avoidance behaviors in rats. Using signaled active avoidance conditioning, rats acquired two-way shuttle responding, to two different auditory stimuli. These behaviors were then extinguished through exposure to the auditory stimuli where shuttling behavior was now without consequence. Subjects were then tested for renewal of avoidance in three distinct renewal sequences (e.g., ABA vs ABB, AAB vs AAA, and ABC vs ABB) in three separate groups of rats. It was found that subjects showed more responding to a stimulus presented outside of its …

The Impact Of Working Memory Load And Anxiety On Attention Bias Modification Training, David Lloyd Yap

Theses and Dissertations

The effect of attention bias modification training (ABMT) on anxiety-related attention bias (AB) in a large (N=204) non-clinical sample was sensitive to working memory load (WML). ABMT produced expected changes in AB in the low-WML, low-anxiety group only. High WML and high anxiety alone and in interaction disrupted ABMT.

Exercise As A Therapeutic For Hiv-1-Associated Neurocognitive Deficits, Michael N. Cranston

Theses and Dissertations

Human Immunodeficiency Virus (HIV-1) afflicts nearly 38 million individuals worldwide (Joseph et al., 2013; “WHO | HIV/AIDS,” 2016). Despite the reduction in disease mortality due to increased use of antiretroviral medication, HIV-1 associated neurocognitive disorder (HAND) affects approximately 50% of HIV infected individuals (Antinori et al., 2007; Castellon, Hinkin, Wood, & Yarema, 1998; Castelo, Sherman, Courtney, Melrose, & Stern, 2006; Cysique & Brew, 2009; Heaton et al., 2011, 2015). The brain itself is particularly sensitive to HIV-1 related viral proteins and viral infection (Masliah, DeTeresa, Mallory, & Hansen, 2000), thus, it is vital to empirically examine potentially effective therapeutics which …

Advancing Understanding Of Dynamic Mechanisms In Onset To Event Models: Discrete Time Survival Mediation With A Time Variant Mediator, Heather Lasky Mcdaniel

Theses and Dissertations

Integrating discrete time survival and mediation analytic approaches, discretetime survival mediation models (DTSM) help researchers elucidate the impact of predictors on the timing of event occurrence. Though application of this model has been gainful in various applied developmental and intervention research contexts, empirical work has yet to consider how DTSM models operate with a mediator that has a varying effect over time. The importance of examining this situation has important impacts for application of the model, given more complex statistical models are required, and subsequent interpretation of model parameters differ from the basic DTSM model. The overarching purpose of this …

Questioning The Modality Of The Occipital Lobe, William J. Brixius

Theses and Dissertations

This dissertation explores the occipital lobe’s response to non-visual inputs, and whether this responsivity partitions into separate localization and identification pathways as seen with visual inputs. We hypothesized that occipital areas may merely prefer visual inputs, while maintaining similar task-based sensory recruitment in response to other senses. Our secondary hypothesis was that the robust occipital activation seen in late-blind participants stems at least initially from standard connections present even in the typically sighted, and that these standard connections are functionally utilized by the typically sighted in spatially relevant non-visual analyses. Our initial literature review supported our hypotheses that the occipital …

Evaluative Conditioning Of Product Preferences: An Eye-Tracking Perspective, Christine E. Weber

Theses and Dissertations

In evaluative conditioning, the affective response toward a neutral stimulus is altered by pairing it with a positive or negative stimulus. One behavioral and two eye tracking studies were conducted to investigate how evaluative conditioning operates on consumer preferences by pairing neutral products with valenced music and using multiple product exemplars and test trials in order to test evaluative effects at the individual level. Study 1 showed an overall positive effect of evaluative conditioning on choice and liking ratings, although there were individual differences in the magnitude and direction of the effect. Study 2 found significant results at the individual …

Neurochemistry, Physiology, And Behavior In A Model Of Gulf War Illness, Victoria A. Macht

Theses and Dissertations

Upon returning from the first Gulf War, soldiers cited a plethora of unexplained physical and cognitive deficits which have since been termed Gulf War Illness (GWI). Presentation of GWI is positively correlated with pyridostigmine bromide (PB) use, which was prophylactically administered to soldiers in response to threats of chemical warfare. To test the overarching hypothesis that PB interacted with stress of deployment to alter neural, endocrine, and immune systems, the following studies used a 2×2 rodent model with 14 days of drug treatment (vehicle; PB) and 10 days of repeated restraint stress (stressed) or non-stressed-control conditions. Results indicate that PB …

Effects Of Fluoxetine On Social And Startle Behavior In The African Cichlid Astatotilapia Burtoni, Stephanie Shih

Theses and Dissertations

The commonly prescribed antidepressant Prozac (fluoxetine) is found in waste water and affects aquatic animals. Here we ask how social hierarchy and startle behavior in an African cichlid fish community is impacted by chronic fluoxetine exposure. Results indicate reduced aggression and startle rates, implying possible ecological consequences.

Using Conditioned Place Preference To Investigate Changes In The Rewarding Effects Of Running And Eating Following Activity-Based Anorexia, Daniella Plaksiy

Theses and Dissertations

We used conditioned place preference to investigate whether activity-based anorexia would enhance the rewarding effects of running, causing running to be more rewarding than eating. We found that food restricted mice showed a clear preference for the food-associated chamber, and a subset of activity-based anorexia mice preferred the wheel-associated chamber.

Reward Preferences In Domestic Horses (Equus Caballus), Elizabeth E. Jaeger

Theses and Dissertations

The present study examined stress response in domestic horses (Equus caballus) to determine if horses show preference for either traditional or natural horsemanship training methods to test the hypothesis that natural horsemanship would induce less stress. Our results show that natural horsemanship rewards elicited lower stress response in horses.

Adult Human Perception Of Distress In The Cries Of Bonobo, Chimpanzee And Human Infants, Taylor Kelly

Theses and Dissertations

Adult human listeners rated their perceived distress based on the recorded vocalizations of bonobo, chimpanzee and human infants. Results found that bonobos were rated highest, chimpanzee and human infants in the high arousal context were rated as lower distress, and human babies in low arousal rated lowest.

Development Of Brain Functional Connectivity And Its Relation To Infant Sustained Attention In The First Year Of Life, Wanze Xie

Theses and Dissertations

This dissertation project studies the development of infant sustained attention and its relation to brain functional connectivity from 6 to 12 months of age. Chapter 1 is a general introduction of the dissertation project. Chapter 2 is a review of the existing literature on the development of infant sustained attention. This chapter includes theories on infant sustained attention and findings from studies using behavioral and psychophysiological measurements. Chapter 3 is a review of the recent advances made in the study of the development of functional connectivity in brain networks. This chapter covers some empirical evidence for the development of functional …

Dimensionality And Instrument Validation In Factor Analysis: Effect Of The Number Of Response Alternatives, Alexander G. Hall

Theses and Dissertations

Despite the great prevalence in both research and application of Factor Analysis (FA), widespread misinterpretation continues to pervade the psychological community in its application for the development and evaluation of psychometric tools. Fundamental measurement questions such as the number of response alternatives needed, and the power to detect poor model fit in non-normal or misspecified data, still remain in need of further investigation. For example, the power of the chi-square statistic used in structural equation modeling decreases as the absolute value of excess kurtosis of the observed data increases. This issue is further compounded with discrete variables, where increasing kurtosis …

Scene Search Guidance Under Salience-Driven And Memory-Driven Demands, Jenn Ha’Aheo Olejarczyk

Theses and Dissertations

Visual search involves selecting relevant information while ignoring irrelevant information. Most search models predict what relevant features attract gaze; yet few consider search guidance from previous knowledge of scenes. This dissertation used eye movements to examine the guidance of attention when an immediate or delayed distractor appeared during novel and repeated searches.

The experiments showed efficient search for repeated scenes, a classic result of contextual cueing. During repeated searches, an immediate attentional bias was found for distractors close to the target location. Automatic and controlled selective attention processes, measured using the antisaccade, were found within search behavior. The final experiment …

Developing Conceptual Understanding And Procedural Fluency In Algebra For High School Students With Intellectual Disability, Andrew J. Wojcik

Theses and Dissertations

Teaching students with Intellectual Disability (ID) is a relatively new endeavor. Beginning in 2001 with the passage of the No Child Left Behind Act, the general education curriculum integrated algebra across the K-12 curriculum (Kendall, 2011; National Governors Association Center for Best Practices & Council of Chief State School Officers, 2010), and expansion of the curriculum included five intertwined skills (productive disposition, procedural fluency, strategic competence, adaptive reasoning, and conceptual understanding) (Kilpatrick, Swafford, & Findell, 2001). Researchers are just beginning to explore the potential of students with ID with algebra (Browder, Spooner, Ahlgrim-Delzell, Harris & Wakeman, 2008; Creech-Galloway, Collins, Knight, …