The Effects Of Chronic Partial Sleep Deprivation On Alcohol Consumption And Delta Fos B Accumulation, Kristian Ponder

Showcase of Graduate Student Scholarship and Creative Activities

The present study explores the relation between sleep restriction and alcohol use and the neural substrates that result from chronic behaviors, such as transcription factors. Transcription factor activity is suggested as a possible outcome of chronic behaviors, such as addiction. Sleep is discussed as possible mediating factor in the relationship between specific transcription factors and alcohol. Analysis will focus on brain areas related to both sleep and reward.

Cognitive Phenotypes And The Evolution Of Animal Decisions, Tamra C. Mendelson, Courtney L. Fitzpatrick, Mark E. Hauber, Charles H. Pence, Rafael L. Rodríguez, Rebecca J. Safran, Caitlin A. Stern, Jeffrey R. Stevens

Faculty Publications

Despite the clear fitness consequences of animal decisions, the science of animal decision making in evolutionary biology is underdeveloped compared with decision science in human psychology. Specifically, the field lacks a conceptual framework that defines and describes the relevant components of a decision, leading to imprecise language and concepts. The ‘judgment and decision-making’ (JDM) framework in human psychology is a powerful tool for framing and understanding human decisions, and we apply it here to components of animal decisions, which we refer to as ‘cognitive phenotypes’. We distinguish multiple cognitive phenotypes in the context of a JDM framework and highlight empirical …

Acute And Chronic Effects Of Inhalants In Intracranial Self-Stimulation, Matthew Tracy

Theses and Dissertations

Inhalants are a loosely defined diverse group of volatile substances which people abuse. Despite widespread misuse of inhalants, there are limited preclinical methods available to study the reinforcement-like properties of inhalants. One procedure which has demonstrated substantial promise as a tool to investigate inhalant pharmacology is the intracranial self-stimulation (ICSS) procedure. ICSS utilizes pulses of electrical stimulation to the mesolimbic reward pathway to serve as a temporally defined and controlled operant reinforcer with a highly adjustable efficacy. The first aim of the project was to characterize the effects of commonly abused inhalants: including toluene, trichloroethane, nitrous oxide, isoflurane and R134a …

Same-Sex Socio-Sexual Interactions Among A Group Of Captive Bottlenose Dolphins (Tursiops Truncatus), Natalia Botero Acosta

Master's Theses

Bottlenose dolphins (Tursiops truncatus) frequently engage in non-reproductive sexual behavior, including homosexual encounters. In order to better understand the nature and function of these interactions, a longitudinal study of the patterns of association and the dynamics of initiator/recipient role exchange was conducted. Underwater video footage of a colony of bottlenose dolphins housed at the Roatan Institute for Marine Sciences (RIMS), collected between March of 2010 and May of 2013, was analyzed. Associations occurring during homosexual interactions were transitory for most individuals. Nonetheless, subsequent analyses allowed the rejection of the null hypothesis of random association, suggesting the existence of …

Spike Field Coherence (Sfc) For Ripples In Rat Hippocampus, Pranav Singla

Honors Scholar Theses

The aim of this project was to determine coherence between two types of neural recordings which can be obtained from the rat hippocampus: spikes and local field potentials. Extracellular recording makes it possible to determine spiking activity from individual neurons in the vicinity of the recording electrode. Local field potential recording gives a combined activity of many neurons (thousands) at once to determine an overall picture of the coordination of the cells in real time. Here we examine the relationship between these two signals, focusing on place cells which spike at their maximal rate only at certain positions in physical …

Effects Of 17Β-Estradiol On Learning And Memory And Strategy Use During A Hole Board Spatial Navigation Task In Aged Male Rats, Megan Berthiaume

Seton Hall University Dissertations and Theses (ETDs)

Treatment with 17β- estradiol has been shown to ameliorate age related deficits in spatial learning and memory as well as to promote the use of an allocentric strategy during spatial navigation. While the majority of research using 17β- estradiol has been done using females rodents, there have been studies showing an improvement in spatial learning and memory and promoted use of allocentric strategies in spatial navigation in males as well. In males testosterone (T) is metabolized into estradiol by aromatase. As circulating levels of T decline with aging there is less available T to be metabolized into estradiol. The current …

Repeated Effects Of The Neurotensin Receptor Agonist Pd149163 In Three Animal Tests Of Antipsychotic Activity: Assessing For Tolerance And Cross-Tolerance To Clozapine, Shinnyi Chou, Collin Davis, Sean Jones, Ming Li

Department of Psychology: Faculty Publications

Neurotensin is an endogenous neuropeptide closely associated with the mesolimbic dopaminergic system and shown to possess antipsychotic-like effects. In particular, acute neurotensin receptor activation can inhibit conditioned avoidance response (CAR), attenuate phencyclidine (PCP)-induced prepulse inhibition (PPI) disruptions, and reverse PCP-induced hyperlocomotion. However, few studies have examined the long term effects of repeated neurotensin receptor activation and results are inconsistent. Since clinical administration of antipsychotic therapy often requires a prolonged treatment schedule, here we assessed the effects of repeated activation of neurotensin receptors using an NTS1 receptor selective agonist, PD149163, in 3 behavioral tests of antipsychotic activity. We also investigated whether …

Reducing Subjectivity: Meditation And Implicit Bias, Diana M. Ciuca

CMC Senior Theses

Implicit association of racial stereotypes is brought about by social conditioning (Greenwald & Krieger, 2006). This conditioning can be explained by attractor networks (Sharp, 2011). Reducing implicit bias through meditation can show the effectiveness of reducing the rigidity of attractor networks, thereby reducing subjectivity. Mindfulness meditation has shown to reduce bias from the use of one single guided session conducted before performing an Implicit Association Test (Lueke & Gibson, 2015). Attachment to socially conditioned racial bias should become less prevalent through practicing meditation over time. An experimental model is proposed to test this claim along with a reconceptualization of consciousness …

An Exploration Of The Wheel-Induced Feeding-Suppression, Stephen Benjamin Peckham

Theses and Dissertations (Comprehensive)

Anorexia nervosa is an enigmatic human condition typified by food-restriction that is often accompanied by extensive exercise. This has been modeled in rats in the wheel-induced feeding-suppression (WIFS) model. In this model, animals are given access to a running-wheel, which induces a volitional drop in food-consumption. Short periods of wheel access have induced a feeding-suppression which is effectively reversed by chlorpromazine administration (Adams et al., 2009). Recent attempts at replicating Adams et al.’s (2009) feeding-suppression have, however, been unsuccessful (Peckham et al., 2013). These attempts raised questions as to whether or not the existing methodology is most effective at suppressing …

A Quantitative Analysis Of The Value-Enhancing Effects Of Nicotine, Bupropion, And Varenicline In Male And Female Rats, Scott Barrett

Department of Psychology: Dissertations, Theses, and Student Research

Smoking and tobacco dependence are serious health concerns in the United States and globally. Reward via the pharmacological effects of nicotine are believed to be the principal motivating factor that drive tobacco dependence. Research reveals differences in sensitivity between males and females to the motivational effects of nicotine in tobacco use. Enhancement of reinforcement value of non-nicotine rewards contributes to overall nicotine reward. Similar value-enhancing effects have been observed by the two most commonly prescribed smoking cessation aids, bupropion and varenicline. The present dissertation investigated the value-enhancing effects of nicotine, bupropion and varenicline in both male and female rats using …

Effects Of Oxytocin On Human Aggression, Joseph L. Alcorn Iii

Dissertations and Theses (Open Access)

EFFECTS OF OXYTOCIN ON HUMAN AGGRESSION

Joseph Louis Alcorn III, B.S.

Advisory Professor: Scott D. Lane, Ph.D.

Human interaction is comprised of common, yet complex, behaviors and the outcomes of these social behaviors can beneficially or detrimentally impact individual and public health. One social behavior that can have profound detrimental outcomes is aggression. Aggression is a class of social behavior that is particularly prevalent in individuals with antisocial personality disorder (ASPD) and comorbid substance use disorder (SUD). Aggression in these individuals can manifest at maladaptive levels that place considerable burdens on public health and communities. Therefore, understanding the neurobehavioral underpinnings …

Change Detection In Rhesus Monkeys And Humans, Deepna T. Devkar, Deepna T. Devkar

Dissertations and Theses (Open Access)

Visual working memory (VWM) is the temporary retention of visual information and a key component of cognitive processing. The classical paradigm for studying VWM and its encoding limitations has been change detection. Early work focused on how many items could be stored in VWM, leading to the popular theory that humans could remember no more than 4±1 items. More recently, proposals have suggested that VWM is a noisy, continuous resource distributed across virtually all items in the visual field, resulting in diminished memory quality rather than limited quantity. This debate about the nature of VWM has predominantly been studied with …

Adolescent Bisphenol-A Exposure Decreases Dendritic Spine Density: Role Of Sex And Age, Rachel E. Bowman, Victoria N. Luine, Hameda Khandaker, Joseph J. Villafane, Maya Frankfurt

Psychology Faculty Publications

Bisphenol-A (BPA), a common environmental endocrine disruptor, modulates estrogenic, androgenic, and anti-androgenic effects throughout the lifespan. We recently showed that low dose BPA exposure during adolescence increases anxiety and impairs spatial memory independent of sex. In the current study, six week old Sprague Dawley rats (n=24 males, n=24 females) received daily subcutaneous injections (40 µg/kg bodyweight) of BPA or vehicle for one week. Serum corticosterone levels in response to a 1 h restraint stress and spine density were examined at age 7 (cohort 1) and 11 (cohort 2) weeks. Adolescent BPA exposure did not alter stress dependent corticosterone responses but …

Effects Of Animal Management Changes On The Activity Budgets And Walking Rates Of Zoo Elephants, Angela Dawn Mackey

Dissertations

The current study aimed to assess the effects of two management strategies, weekly rototilling of the enclosure and the provision of unpredictable foraging opportunities, on the daily behavior of six elephants housed at the San Diego Zoo. Observations took place from January to June 2013 and were conducted throughout a 24- hour period. The study was divided into three phases, each two months in duration. During the first phase (baseline) no changes were made to the current management routine of the elephants. In Phase 2, rototilling of the elephant enclosures was increased from once monthly to once per week, while …

Effects Of 5-Hydroxytryptamine 2c Receptor Agonist Mk212 And 2a Receptor Antagonist Mdl100907 On Maternal Behavior In Postpartum Female Rats, Weihai Chen, Qi Zhang, Wenxin Su, Yu Yang, Jing Qiao, Nan Sui, Ming Li

Department of Psychology: Faculty Publications

Maternal behavior in rats is a highly motivated and well-organized social behavior. Given the known roles of serotonin (5-HT) in emotion, motivation, social behavior, and major depression – and its known interaction with dopamine – it is likely that serotonin also plays a crucial role in this behavior. So far, there are surprisingly few studies focusing on 5-HT in maternal behavior, except for maternal aggression. In the present study,we examined the effects of 5-HT_2C receptor agonism and 5-HT_2A receptor antagonism on maternal behavior in postpartum female rats.We hypothesized that activation of 5-HT_2C receptors and blockade of 5-HT …

Gesture Sequence In Captive Orangutans (Pongo Pygmaeus), Amanda Leone Carner

All Master's Theses

The most flexible form of communication may be gestures used by large body apes. The current study focused on gesture sequence in five captive orangutans at Woodland Park Zoo. We observed 305 gestures with 185 gestures (60.65%) occurring in 61 sequences in 2,482 minutes of data. Overall, orangutans used 272 tactile gestures (89 .18% ), 29 visual gestures (9 .50%) and 4 facial expressions ( 1.31 % ). In sequence, orangutans used 176 tactile gestures (95.14%), 7 visual gestures (3.78%), and 2 facial expressions (1.08%). Overall, a two-way repeated measure ANOV A showed significantly more tactile (x=26.9) than visual (x=2.9) …

Health Promotion In Multiple Domains: Capitalizing On The Spillover Effect, Gabrielle Maria D'Lima

Psychology Theses & Dissertations

Lifestyle behaviors, such as physical activity and food consumption choices, play a critical role in the development of chronic diseases and ultimately mortality. Optimally, multiple health-related behaviors are changed to reduce risk rather than targeting only one risk behavior. The purpose of the current research was to examine the potential utility of the spillover effect in the application of a multiple health behavior intervention. The online intervention developed in this study aimed primarily to foster self-regulation, bolstered by impulsivity control and self-efficacy, in one health-related behavior (i.e., physical activity) in order to potentially affect change in other health-related behaviors (e.g., …

Animals' Capability To Bond And The Implications That Follow, Falyn Goldfarb

Honors College Theses

This paper explores the ways in which humans have historically viewed animals, with a focus on Descartes theory automata. Further concepts of the problem of different minds, inherent value, empathy, love, friendship, grief, isolation, anthropomorphism, and biochemistry (focusing on oxytocin, cortisol and the prefrontal cortex) are all explored. Numerous literature reviews are used as examples to fight against the argument that animals are merely machines and can therefore be used and abused. Animal social bonds, including parent-child, purely social, and animal-human, are analyzed for their evolutionary and biological purposes in attempt to highlight the relationships that are not obviously valuable …

A Bittersweet Investigation Of Availability And Nutritive Value As Determinants Of Volitional Sucrose Consumption, Milan D. Valyear

Theses and Dissertations (Comprehensive)

Rats given ~24 h access to a 4% sucrose solution every 3^rd day (E3DA) consume about 100 g more solution than rats with continuous, everyday access (EDA). Under the same EDA-E3DA conditions rats will consume similar amounts of a more concentrated 8 or 16% sucrose solutions (Eikelboom, Hewitt, & Adams, Unpublished). It maybe that with these more concentrated solutions rats hit a satiety limit that prevents a difference between EDA and E3DA consumption from being evident. Experiment 1 was conducted to investigate the effect of adding quinine to 4% and 8% sucrose solutions with the intention of reducing consumption …

Message Matters: Application Of The Theory Of Planned Behavior To Increase Household Hazardous Waste Program Participation, Amy Dyer Cabaniss

Antioch University Dissertations & Theses

Removing household hazardous waste (HHW) from the municipal solid waste stream is important to protect health, safety and the environment. Communities across the U.S. separate HHW from regular trash for disposal with hazardous waste, however nationally, participation rates are low with only five to ten percent of households estimated to participate in any given collection. This two-part study used the Theory of Planned Behavior (TPB) to understand individuals’ beliefs and attitudes toward HHW collections, and to develop a print message intervention to increase participation. In Study 1, respondents (N = 983) completed a survey administered to homeowners in the Connecticut …

Congruent And Incongruent Effects Of Ethnic Music On Ethnic Menu Item Selection, Ryan David Muniz

Graduate Theses and Dissertations

This study investigated what impact ethnic music had on ethnic menu item selection. College students were randomly divided into three groups and listened to one randomly assigned sound treatment in sensory booths. Three hundred and five participants completed the questionnaire with measures of expected price value and willingness to pay value. One of the groups listened to an Italian folk music, the second group listened to a Thai folk music, and the third group listened to a restaurant background noise in order to examine if the music will impact each participant menu items selection and perceived price values. The result …

Strength, But Not Direction, Of Handedness Is Related To Height, Ruth E. Propper, Tad T. Brunyé, Karly Frank, Sean E. Mcgraw

Department of Psychology Faculty Scholarship and Creative Works

Left-handers are reputed to be shorter than right-handers. However, previous research has confounded handedness direction (left- versus right-handedness) with handedness strength (consistency with which one hand is chosen across a variety of tasks; consistent- versus inconsistent-handedness). Here, we support a relationship between handedness strength, but not direction, and stature, with increasing inconsistent-handedness associated with increasing self-reported height.

Resistance Training Behaviors In College-Aged Women 2013, Melanie Kornblatt

Master's Theses

The purpose of this study was to develop an understanding of women’s training behavior in the weight room. A secondary purpose was to determine what their beliefs and perceptions were in regards to lifting weights. Participants were college-aged females ranging in age from 17-29 years. Observations of weight lifting activities were conducted during peak hours of operation (Mondays, Wednesdays, and Fridays from 3- 6pm) in the fitness facility. A total of 60 hours of observations were conducted over a period of four weeks. In addition to observations, two focus groups were conducted. Participants were divided into two specific groups: I …

Accessing Learning In The Adult Zebrafish With A Novel Associative Learning Task, David Joseph Jouandot Ii

Dissertations

The zebrafish (Danio rerio) is accepted in the developmental and genomic communities as a model organism. However, the capacity for the zebrafish as a behavioral model has yet to be fully acknowledged. The research presented provides evidence validating the novel task, aids in gaining a better understanding of the learning processes, and identifies individual differences. The novel associative learning task differs from any present well established behavioral model and lends itself to future development. The task provides the zebrafish community with a high output behavioral task which is readily replicated and allows one researcher to test between eight …

Tactile Behavior In A Group Of Captive Rough-Toothed Dolphins As A Function Of Opportunities To Play With Objects, Kelly Ann Caffery

Dissertations

Cetaceans live in complex physical and social environments that are frequently changing. In contrast, the captive environment for marine mammals is often lacking in stimulation. As a result, enrichment is often used to increase species-typical behaviors and enhance the well-being of the animals. The purpose of this study was to compare the effects of enrichment objects on the social behavior of a group of seven captive rough-toothed dolphins (Steno bredanensis). Observations of this species in the wild suggest it may have a particular affinity for tactile and object play behaviors. Therefore, these behavior categories were a primary focus …

Effects Of Food Dispersion On Dominance Related Behaviors In Garnett's Bushbaby (Otolemur Garnettii)?, Kyle Daniel Edens

Dissertations

Socio-ecological theorists tie primate social structure diversity to variations in habitats within which primate species reside. This premise permits laboratory researchers to investigate specific factors that influence or relate to social structure formation and maintenance. The focus of the current investigation was three fold. We first aimed to determine the relationships between traditional and non-traditional behavioral measures of dominance, then evidence for dominance hierarchy formation was examined, and various hypotheses were tested to discern if adjustments in the foraging context altered social behaviors in Garnett’s bushbaby (Otolemur garnettii). It was determined that animals likely to displace conspecifics were …

The Effects Of Selected Drugs On The Memory Recall Of Sleep Deprived Mice, Jenn Pauldurai

Capstone Research Projects

Humans often make use of the neurotransmission altering effects of drugs such as caffeine, ephedrine, and ethanol. These drugs induce changes in memory and learning ability, specifically when used for sleep deprivation. English white mice (Mus musculus) have been shown to exhibit similar cognitive changes when administered drugs while sleep deprived. A sample of 20 mice was divided into three experimental groups (each group receiving a different drug) and one control group. Maze-testing demonstrated that mice performance decreased with sleep deprivation (Treatment-1) but all groups returned to baseline performance when injected (IP) with selected drugs (Treatment-2), regardless of …

Lateralized Difference In Tympanic Membrane Temperature: Emotion And Hemispheric Activity, Ruth E. Propper, Tad T. Brunyé

Department of Psychology Faculty Scholarship and Creative Works

We review literature examining relationships between tympanic membrane temperature (TMT), affective/motivational orientation, and hemispheric activity. Lateralized differences in TMT might enable real-time monitoring of hemispheric activity in real-world conditions, and could serve as a corroborating marker of mental illnesses associated with specific affective dysregulation. We support the proposal that TMT holds potential for broadly indexing lateralized brain physiology during tasks demanding the processing and representation of emotional and/or motivational states, and for predicting trait-related affective/motivational orientations. The precise nature of the relationship between TMT and brain physiology, however, remains elusive. Indeed the limited extant research has sampled different participant populations …

The Effect Of Visual Wulst Lesions And Trigeminal Nerve Sectioning On The Discrimination Of Magnetic Inclination In The Homing Pigeon (Columba Livia), Merissa Acerbi

Honors Projects

The ability of homing pigeons to return to their loft from unknown places has fascinated scientists for centuries. It is well established that homing pigeons, like migratory birds, posses an innate magnetic inclination compass to determine direction by measuring the angle between the magnetic field vector and the Earth's surface. Recent work has indicated that the avian magnetic compass is light mediated and appears to mediate magnetic information to the brain. This occurs via a visual pathway with processing in the visual Wulst area of the forebrain. There is, however, also evidence from other avian species that magnetic direction may …

Asymmetry In Resting Alpha Activity: Effects Of Handedness, Ruth E. Propper, Jenna Pierce, Mark W. Geisler, Stephen D. Christman, Nathan Bellorado

Department of Psychology Faculty Scholarship and Creative Works

Frontal electroencephalographic (EEG) alpha band power during rest shows increased right, and/or decreased left, hemisphere activity under conditions of state or trait withdrawal-associated effect. Non-right-handers (NRH) are more likely to have mental illnesses and dispositions that involve such withdrawal-related effect. The aim of the study was to examine whether NRH might be characterized by increased right, relative to left, hemisphere activity during rest. Methods: The present research investigated that hypothesis by examining resting EEG alpha power in consistently-right-handed (CRH) and NRH individuals. Results: In support of the hypothesis, NRH demonstrated decreased right hemisphere alpha power, and therefore increased right hemisphere …