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Cognitive Psychology Commons™

Open Access. Powered by Scholars. Published by Universities.®

2018

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Articles 301 - 302 of 302

Full-Text Articles in Cognitive Psychology

Crest In The Nucleus Accumbens Core Regulates Cocaine Conditioned Place Preference, Cocaine-Seeking Behavior, And Synaptic Plasticity, Yasaman Alaghband, Eniko Kramar, Janine L. Kwapis, Earnest S. Kim, Thekla J. Hemstedt, Alberto J. Lopez, Andre O. White, Amni Al-Kachak, Osasumwen V. Aimiuwu, Kasuni K. Bodinayake, Nicole C. Oparaugo, Joseph Han, K. Matthew Lattal, Marcelo A. Wood Jan 2018

Crest In The Nucleus Accumbens Core Regulates Cocaine Conditioned Place Preference, Cocaine-Seeking Behavior, And Synaptic Plasticity, Yasaman Alaghband, Eniko Kramar, Janine L. Kwapis, Earnest S. Kim, Thekla J. Hemstedt, Alberto J. Lopez, Andre O. White, Amni Al-Kachak, Osasumwen V. Aimiuwu, Kasuni K. Bodinayake, Nicole C. Oparaugo, Joseph Han, K. Matthew Lattal, Marcelo A. Wood

Faculty Publications - Psychology Department

Epigenetic mechanisms result in persistent changes at the cellular level that can lead to long-lasting behavioral adaptations. Nucleosome remodeling is a major epigenetic mechanism that has not been well explored with regards to drug-seeking behaviors. Nucleosome remodeling is performed by multi-subunit complexes that interact with DNA or chromatin structure and possess an ATP-dependent enzyme to disrupt nucleosome-DNA contacts and ultimately regulate gene expression. Calcium responsive transactivator (CREST) is a transcriptional activator that interacts with enzymes involved in both histone acetylation and nucleosome remodeling. Here, we examined the effects of knocking down CREST in the nucleus accumbens (NAc) core on drug-seeking …


Case Study Of The Four-Year Neuropsychological Changes In An Elderly Male With Possible Chronic Traumatic Encephalopathy, Patrick Martin Jan 2018

Case Study Of The Four-Year Neuropsychological Changes In An Elderly Male With Possible Chronic Traumatic Encephalopathy, Patrick Martin

Antioch University Dissertations & Theses

Research demonstrates that the brain's response to Traumatic Brain Injury (TBI) is variable with age and the effects of TBI on the elderly are a critical and global public health concern, from both a medical and a neuropsychological perspective. Currently, there is scant research on the effects of TBI, including Chronic Traumatic Encephalopathy (CTE), on the elderly. Specifically, there is a paucity of literature regarding longitudinal neuropsychological changes in elderly post- TBI individuals. This dissertation will present a Single Case Research Design (SCRD) analysis of an elderly individual with possible Chronic Traumatic Encephalopathy and the associated neuropsychological changes over 49-months. …