Cognition and Perception Commons^™

Computational Thinking As A Novel Framework For Enhancing Cognitive Organization In Older Adults With Cognitive Frailty (Letter To The Editor), Daisuke Akiba

Publications and Research

As aging populations grow, especially in high-income nations, the burden of dementia-related care continues to escalate both economically and socially. In response, this article introduces Computational Thinking (CT) as a novel, non-pharmacological framework to support cognitive organization in older adults experiencing cognitive frailty. Though CT has gained traction in fields like PK-16 education, including special education, for enhancing executive function and problem-solving, it has not yet been applied to geriatric- or memory-care contexts. This perspective proposes that CT’s core components (i.e., decomposition, pattern recognition, abstraction, and algorithmic thinking) may align with residual cognitive strengths in mild-to-moderate dementia, offering a strengths-based, …

Associations Between Deficit Accumulation Frailty And Baseline Markers Of Lifestyle In The Us Pointer Trial, Mark A Espeland, Yitbarek N Demesie, Kayloni Olson, Samuel N Lockhart, Sarah E Tomaszewski Farias, Maryjo L Cleveland, Christy C Tangney, Lucia Crivelli, Heather M Snyder, Michele K York, Laura D Baker, Rachel A Whitmer, Rena R Wing, Katelyn R Garcia, Kathryn E Callahan

Faculty, Staff and Students Publications

BACKGROUND: Multidomain lifestyle interventions may have the potential to slow biological aging as captured by deficit accumulation frailty indices. We describe the distribution and composition of the 49-component frailty index developed by the U.S. POINTER clinical trial team of investigators and assess its cross-sectional associations with sociodemographic factors and markers chosen to be representative of behaviors targeted by the trial's multidomain interventions.

METHODS: We draw baseline data from the 2 111 volunteers enrolled in U.S. POINTER who were ages 60-79 years and at increased risk for cognitive decline. Frailty components were grouped into 9 domains. Associations that frailty index scores …

Study Design And Methods: Us Study To Protect Brain Health Through Lifestyle Intervention To Reduce Risk (Us Pointer), Laura D Baker, Heather M Snyder, Mark A Espeland, Rachel A Whitmer, Miia Kivipelto, Nancy Woolard, Jeffrey Katula, Kathryn V Papp, Jennifer Ventrelle, Sarah Graef, Marcus A Hill, Scott Rushing, Julia Spell, Laura Lovato, Deborah Felton, Benjamin J Williams, Mina Ghadimi Nouran, Rema Raman, Tiia Ngandu, Alina Solomon, Sharon Wilmoth, Maryjo L Cleveland, Jeff D Williamson, Katherine L Lambert, Sarah Tomaszewski Farias, Claire E Day, Christy C Tangney, Darren R Gitelman, Olivia Matongo, Terrianne Reynolds, Valory N Pavlik, Melissa M Yu, Ashley S Alexander, Richard Elbein, Ann Marie Mcdonald, Stephen Salloway, Rena R Wing, Susan Antkowiak, Martha Clare Morris, Maria C Carrillo

Faculty, Staff and Students Publications

INTRODUCTION: The U.S. study to protect brain health through lifestyle intervention to reduce risk (U.S. POINTER) is conducted to confirm and expand the results of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) in Americans.

METHODS: U.S. POINTER was planned as a 2-year randomized controlled trial of two lifestyle interventions in 2000 older adults at risk for dementia due to well-established factors. The primary outcome is a global cognition composite that permits harmonization with FINGER.

RESULTS: U.S. POINTER is centrally coordinated and conducted at five clinical sites (ClinicalTrials.gov: NCT03688126). Outcomes assessments are completed at baseline and …

Smart-Home Concept For Remote Monitoring Of Instrumental Activities Of Daily Living (Iadl) In Older Adults With Cognitive Impairment: A Proof Of Concept And Feasibility Study, Myeounggon Lee, Ram Kinker Mishra, Anmol Momin, Nesreen El-Refaei, Amir Behzad Bagheri, Michele K York, Mark E Kunik, Marc Derhammer, Borna Fatehi, James Lim, Rylee Cole, Gregory Barchard, Ashkan Vaziri, Bijan Najafi

Center on Aging Staff Publications

Assessment of instrumental activities of daily living (IADL) is essential for the diagnosis and staging of dementia. However, current IADL assessments are subjective and cannot be administered remotely. We proposed a smart-home design, called IADLSys, for remote monitoring of IADL. IADLSys consists of three major components: (1) wireless physical tags (pTAG) attached to objects of interest, (2) a pendant-sensor to monitor physical activities and detect interaction with pTAGs, and (3) an interactive tablet as a gateway to transfer data to a secured cloud. Four studies, including an exploratory clinical study with five older adults with clinically confirmed cognitive impairment, who …

Driving Habits, Cognition, And Health-Related Quality Of Life In Middle-Aged And Older Adults With Hiv, Josiah J. Robinson, Tess Walker, Cierra Hopkins, Brittany Bradley, Peggy Mckie, Jennifer S. Frank, Caitlin N. Pope, Pariya L. Fazeli, David E. Vance

Graduate Center for Gerontology Faculty Publications

Cognitive impairment is known to increase with aging in people living with HIV (PLWH). Impairment in cognitive domains required for safe driving may put PLWH at risk for poor driving outcomes, decreased mobility, and health-related quality of life (HRQoL). This study described the driving behaviors of middle-aged and older PLWH and examined correlations between driving behaviors and cognitive functioning (Aim 1), and driving behaviors and HRQoL domains (Aim 2). A sample of 260 PLWH ages 40 and older completed a comprehensive assessment including a battery of cognitive tests, an HRQoL measure, and a measure of self-reported driving habits. Associations between …

Do Emotion Words Influence Age Effects In Delayed Match-To-Sample Performance For Emotional Faces?, Ying-Han Li

Masters Theses & Specialist Projects

Age differences are apparent in using verbal labels of emotion to categorize emotion face stimuli. Particularly, older adults have more difficulty detecting emotion cues like anger and fear relative to younger adults, but seem to have less difficulty with disgust cues. However, age differences are diminished in situations when participants are limited to two possible emotion choices or are required to simply match stimuli based on emotion cues without the use of labels. One question that emerges from the disparities in these findings is the role that emotion labels themselves play in driving possible age differences in emotion perception. The …

Outdoor Air Pollution Exposure And Inter-Relation Of Global Cognitive Performance And Emotional Distress In Older Women, Andrew J. Petkus, Xinhui Wang, Daniel P. Beavers, Helena C. Chui, Mark A. Espeland, Margaret Gatz, Tara Gruenewald, Joel D. Kaufman, Joann E. Manson, Susan M. Resnick, James D. Stewart, Gregory A. Wellenius, Eric A. Whitsel, Keith Widaman, Diana Younan, Jiu-Chiuan Chen

Psychology Faculty Articles and Research

The interrelationships among long-term ambient air pollution exposure, emotional distress and cognitive decline in older adulthood remain unclear. Long-term exposure may impact cognitive performance and subsequently impact emotional health. Conversely, exposure may initially be associated with emotional distress followed by declines in cognitive performance. Here we tested the inter-relationship between global cognitive ability, emotional distress, and exposure to PM2.5 (particulate matter with aerodynamic diameter 2 (nitrogen dioxide) in 6118 older women (aged 70.6 ± 3.8 years) from the Women’s Health Initiative Memory Study. Annual exposure to PM_2.5 (interquartile range [IQR] = 3.37 μg/m³) and NO₂ (IQR …

The Project Talent Twin And Sibling Study: Zygosity And New Data Collection, Carol A. Prescott, Ellen E. Walters, Thalida Em Arpawong, Catalina Zavala, Tara L. Gruenewald, Margaret Gatz

Psychology Faculty Articles and Research

The Project Talent Twin and Sibling (PTTS) study includes 4481 multiples and their 522 nontwin siblings from 2233 families. The sample was drawn from Project Talent, a U.S. national longitudinal study of 377,000 individuals born 1942–1946, first assessed in 1960 and representative of U.S. students in secondary school (Grades 9–12). In addition to the twins and triplets, the 1960 dataset includes 84,000 siblings from 40,000 other families. This design is both genetically informative and unique in facilitating separation of the ‘common’ environment into three sources of variation: shared by all siblings within a family, specific to twin-pairs, and associated with …

The Influence Of Aging, Gaze Direction, And Context On Emotion Discrimination Performance, Alyssa Renee Minton

Masters Theses & Specialist Projects

This study examined how younger and older adults differ in their ability to discriminate between pairs of emotions of varying degrees of similarity when presented with an averted or direct gaze in either a neutral, congruent, or incongruent emotional context. For Task 1, participants were presented with three blocks of emotion pairs (i.e., anger/disgust, sadness/disgust, and fear/disgust) and were asked to indicate which emotion was being expressed. The actors’ gaze direction was manipulated such that emotional facial expressions were depicted with a direct gaze or an averted gaze. For Task 2, the same stimuli were placed into emotional contexts (e.g., …

Implicit Attitudes Of Asian American Older Adults Toward Aging, Anita Ho

Scripps Senior Theses

Greenwald, McGhee, and Schwartz (1998) developed the Implicit Association Test (IAT), a measure of mental associations between target pairs and positive or negative attributes. Highly associative categories yield faster responses than the reverse mental associations, which is thought to reflect implicit attitudes toward stereotypes. The present study investigated the effect of ethnic group on one’s implicit attitudes toward aging and gender stereotypes by comparing two groups of older adults, Asian Americans and Caucasian Americans, that likely hold different culture values. Past qualitative studies have established the existence of mental health stigma in Asian American populations, including negative Asian American perceptions …

Assessing Working Memory In Mild Cognitive Impairment With Serial Order Recall, Sheina Emrani

Theses and Dissertations

Background: Working memory (WM) is often assessed with serial order tests such as repeating digits backward. In prior dementia research using the Backward Digit Span subtest (BDT) only aggregate test performance was examined. The current research tallied primacy/ recency effects; out-of-sequence transposition errors; perseverations and omissions to assess WM deficits in patients with mild cognitive impairment (MCI). Methods: Memory clinic patients (n= 66) were classified into three groups - single domain amnestic MCI (aMCI), combined mixed domain/ dysexecutive MCI (mixed/dys MCI), and non-MCI where patients did not meet criteria for MCI. Serial order/ WM ability was assessed by …

Aging And The Perception Of Coherent Motion, Lindsey Marie Shain

Masters Theses & Specialist Projects

The aperture problem describes an effect by which a contoured stimulus, moving behind an aperture with both ends occluded, appears to move in a direction perpendicular to its own orientation. Mechanisms within the human visual system allow us to overcome this problem and integrate many of these locally ambiguous signals into the perception of globally coherent motion. In the current experiment, younger and older observers viewed displays composed of either 64 or 9 straight contours, arranged in varying orientations and moving behind circular apertures. Because these lines moved behind apertures, their individual local motions were ambiguous with respect to direction …

Combined Mnemonic Strategy Training And High-Definition Transcranial Direct Current Stimulation For Memory Deficits In Mild Cognitive Impairment, Benjamin M. Hampstead, Krishnankutty Sathian, Marom Bikson, Anthony Y. Stringer

Publications and Research

Introduction: Memory deficits characterize Alzheimer’s dementia and the clinical precursor stage known as mild cognitive impairment. Nonpharmacologic interventions hold promise for enhancing functioning in these patients, potentially delaying functional impairment that denotes transition to dementia. Previous findings revealed that mnemonic strategy training (MST) enhances long-term retention of trained stimuli and is accompanied by increased blood oxygen level–dependent signal in the lateral frontal and parietal cortices as well as in the hippocampus. The present study was designed to enhance MST generalization, and the range of patients who benefit, via concurrent delivery of transcranial direct current stimulation (tDCS).

Methods: This protocol describes …

Age-Related Differences In Context-Specificity Benefits Ambiguous Predictive Learning, Catherine Luna

Mahurin Honors College Capstone Experience/Thesis Projects

The present study investigated age differences in the context-specificity effect in learning. Ambiguity was manipulated in two conditions in a predictive learning paradigm (Callejas-Aguilera & Rosas, 2010) to encourage participants to attend to context. In the ambiguous condition, foods led to the presence of the illness equally as often as its absence. In the non-ambiguous condition, foods consistently led to the presence of the illness or consistently lead to its absence. Participants were instructed to make predictive judgments for foods leading to the presence of an illness in one of two restaurant contexts. During the test, participants made predictive judgments …

Emotion Regulation In Relation To Cognitive Functioning In The Preclinical Stages Of Dementia, Erica P. Meltzer

Dissertations, Theses, and Capstone Projects

Emotion regulation (ER) is essential for effective functioning in daily life. Research suggests that ER improves in older adulthood despite concomitant declines in cognition and the presumed neural substrates of ER. The current understanding of ER in older adulthood, and particularly of the relationship between ER and cognition in older adulthood, is limited. This is likely because the construct of ER is challenging to operationalize and, therefore, difficult to study.

The current study investigates ER in relation to cognitive functioning, specifically executive functioning and memory, in individuals with varying degrees of cognitive difficulties (i.e., in the preclinical stages of dementia). …

The Effects Of Age And Task On Visual Emotion Processing, Nicole Elaine Chambers

Masters Theses & Specialist Projects

Younger adults’ perception of and attention to facial stimuli are enhanced by positive and negative emotional expressions, with negativity leading to a greater benefit than positivity. Conversely, older adults demonstrate a positivity bias, devoting more attention to positive stimuli and less to negative. It is unclear if age differences in these attentional preferences emerge due to differences in how their perceptual systems respond to positive and negative stimuli. Emotional facial expressions elicit enhanced P1 and N170 components of visually-evoked event-related potentials (ERP) over posterior scalp regions associated with vision. The current study examined the extent to which angry and happy …

Memory, Cognition, And The Effect Of A Music Intervention On Healthy Older Adults, Shannon L. Bowles

Theses and Dissertations--Gerontology

Music is a powerful modality that can bring about changes in individuals of all ages. This research employed both an experimental and quasi-experimental design to identify the effects of music as it influenced psychological well-being, memory, and cognition among older adults. Specifically, it addressed three aims: (a) To determine to what extent learning to play a music instrument later in life influenced psychological well-being and cognitive function of non-institutionalized healthy seniors, (b) To determine the effects of the amount of music involvement on psychological well-being and cognitive function (c) To determine the benefit of music for those with limited/no music …

Young And Older Adults’ Beliefs About Effective Ways To Mitigate Age-Related Memory Decline, Michael Horhorta, Tara T. Lineweaver, Monique Ositelu, Kristi Summers, Christopher Herzog

Scholarship and Professional Work - LAS

This study investigated whether young and older adults vary in their beliefs about the impact of various mitigating factors on age-related memory decline. Eighty young (ages 18–23) and eighty older (ages 60–82) participants reported their beliefs about their own memory abilities and the strategies that they use in their everyday lives to attempt to control their memory. Participants also reported their beliefs about memory change with age for hypothetical target individuals who were described as using (or not using) various means to mitigate memory decline. There were no age differences in personal beliefs about control over current or future memory …

Examining Neurophysiological Evidence Of Age-Related Interactions Of Sensory And Cognitive Processes During Speech Processing, Cady Kristen Block

Psychology Theses & Dissertations

The present study sought to examine the contribution of sensory and cognitive factors on speech processing as evidenced by ERP measures and to find support for the Sensory Cognitive Interaction Theory (SCIT) and the Effortfulness Hypothesis in that older adults. who experience sensory deficits with normal aging. must put forth increased effort during early sensory stages of speech processing that may compromise subsequent semantic performance and recall of information. In the present investigation. younger and older adults performed a sentence verification task at low and high presentation levels (PL). Accuracy and response time to sentence verifications were assessed along with …