Biological Psychology Commons^™

Barriers To Care, Depressive Symptoms, And Moderating Factors Among Patients With Esrd, Amarachukwu O. Nwangwu

Honors Theses

End-Stage Renal Disease (ESRD) is the fifth and final stage of Chronic Kidney Disease (CKD) and has been reported to have the highest prevalence rate in the United States, with about 2,242 cases per million in the total population in 2017 (Johansen et al., 2021). Current studies document a high prevalence of depression among patients with ESRD which may lead to increased mortality (Shirazian et al., 2017). Additionally, barriers in access to care, which may be understood as the barriers that prevent individuals from seeking mental health services, has been linked to increased levels of undertreatment (Clement et al., 2012). …

What Does “Avoidance Mode” Feel Like? The Association Between Avoidance Awareness And Negative Affect In The Moment, Mamie Ziegler

Honors Theses

For students in an academic setting, task avoidance is a common behavioral strategy used to cope with the unpleasant emotions associated with schoolwork and completing assignments. However, when this form of behavioral avoidance becomes a pattern, it has the potential to lead to negative long-term consequences–such as worse academic outcomes and increased stress. To counteract maladaptive behaviors such as task avoidance, a certain level of self-awareness of such behaviors may be necessary–even if this awareness leads to more negative emotions at first. To analyze the relationship between student task avoidance and emotions, the following study utilizes ecological momentary assessment (EMA) …

Does Chronic Risperidone Administration Affect Food Reinforcement In Adulthood In Mice?, Francis Torres, Paul Soto

LSU Master's Theses

Second-generation antipsychotics (SGAs) increase weight gain and food consumption in humans and non-human animals. It has been speculated that SGAs increase the reinforcing effects of food, which increases food consumption and drives weight gain. The current study evaluated the effects of risperidone on sucrose reinforcement in male and female C57BL/6J mice using economic demand assessments. Demand for sucrose was measured by varying the fixed ratio (FR) value required to produce sucrose delivery across experimental sessions using five FR values: 1, 5, 15, 30, and 45. The effects of acute risperidone administration on demand for sucrose were first assessed by orally …

Classical Conditioning Of Cognitive States, Arthur Burns

Neuroscience Honors Papers

Classical conditioning has been a fundamental concept and practice throughout the history of psychology. While classical conditioning traditionally seeks to elicit target behaviors in correlation to specific stimuli, we sought to do the same with cognitive states in place of behaviors. Specifically, we wanted to determine the effectiveness of conditioning states of cognitive arousal in human participants in conjunction with cues presented in a designed learning task. We designed a cognitive task specifically for this research, referred to as “the Tone Pitching Task”, which utilized a combination of working memory and mental processing in order to elicit cognitive arousal and …

Borderline Personality Symptoms And Relationship Threat: The Moderating Role Of Perceived Parental Rejection, Elsa Baumgartner

Departmental Honors & Graduate Capstone Projects

Individuals with borderline personality disorder (BPD) often perceive relationship threats more intensely, resulting in increased emotional reactivity. However, this link has never been examined with physiological measures in “real time,” nor have reports of perceived parental rejection ever been investigated as a potential moderator of this link. To fill this gap, the present study induced romantic relationship threat, after which participants completed an emotional reactivity task while electroencephalography data were recorded. Results reveal that higher levels of BPD features were associated with increased emotional reactivity, indicated by larger late positive potential (LPP) amplitudes, to negative stimuli in the face of …

Substance Use Disorders, Cognitive Dysfunction, And Neurodivergence In Emerging Adulthood, David Posada, Jordyn Hebert

Symposium of Student Scholars

Substance Use Disorders, Cognitive Dysfunction, and Neurodivergence in Emerging Adulthood

Posada, D., Herbert, J., Weingast, L., Holliday, E.

Cognitive functioning in college students with substance use disorders (SUD) has been widely researched, however, discussions have largely concentrated on executive functions (EF) such as working memory, flexible thinking, and self-control. Literature on the relationship between cognitive dysfunction and SUD has largely underreported the influence of Attention Deficit/Hyperactivity Disorders (ADD/ADHD) and other neurodivergent characteristics. The current review explores the state of the literature on the relationship between neurodivergence, cognitive dysfunction, and SUD in emerging adulthood. More specifically, it speculates whether college students …

Heart Rate Variability Following Treatment For Ptsd: Testing The Polyvagal Theory, Brittany F. Goodman

Dissertations

Posttraumatic stress disorder (PTSD) has been linked to lower heart rate variability (HRV), including measures of vagal tone. Treatments targeting the autonomic nervous system (ANS) have demonstrated efficacy in improving vagal tone, but it is less clear whether similar effects can also be achieved with cognitive therapies. The polyvagal theory has suggested that symptoms of social dysfunction are linked to vagal tone through a phylogenetically organized response to stress. HRV was collected during rest, reactivity (exposure to personalized trauma scripts), and recovery using a scripted imagery paradigm in female PTSD positive physical and sexual assault survivors (N = 41) …

Sex Differences In Lateral Hypothalamic Extracellular Glucose Concentrations During Cumulative Dosing Of Methamphetamine In Rats, Joshua A. Jolton

Honors Program: Senior Projects (Public)

The present study experimentally investigated sex differences in lateral hypothalamic glucose concentrations following cumulative dosing of methamphetamine. Male (n=17) and female (n=11) rats were surgically implanted with enzyme-based glucose biosensors in the lateral hypothalamus. Rats then received a saline injection followed by four methamphetamine doses (0.025 mg/kg, 0.05 mg/kg, 0.1 mg/kg, and 0.2 mg/kg) spaced 55 minutes apart. We found that while there was a general decrease in glucose baseline throughout the study for both sexes, the magnitude of the decrease was significantly greater in females compared to males. On a rapid timescale, fixed sex effects existed at the lower …

Evaluation Of Hippocampal Allostatic Load-Associated Factors In Animal Models Of Post-Traumatic Stress Disorder: Relevance To Human Ptsd, Dennis Parker Kelley

LSU Doctoral Dissertations

Post-traumatic stress disorder (PTSD) is associated with elevated allostatic load, nearly double the risk for metabolic syndrome, reduced hippocampal volume, and contextual memory processing deficits. Emerging evidence suggests that these stress effects may predispose individuals to the development of PTSD, and there is a known relationship between chronic stress and metabolic dysfunction. In this work, we utilized two rat models of PTSD to explore these connections. We used an acute predator odor stressor to investigate the relationship between PTSD-like behaviors and mitochondrial dysfunction in the hippocampus of rats, and we observed that conditioned place avoidance was associated with reduced mitochondrial …

Adapting Small Unmanned Aerial Systems For Behavioral Research With Coastal Marine Mammals, Eric Angel Ramos

Dissertations, Theses, and Capstone Projects

Marine mammals inhabit aquatic worlds where their subsurface behavior, cryptic surface profiles, and movements make them difficult to study. New tools are needed to study coastal marine mammals in a world increasing impacted by climate change related shifts in weather and animal distribution patterns. Unmanned aerial systems (UAS) are important remote-sensing tools for studying a range of wildlife including terrestrial and aquatic flora and fauna. These systems offer flexible platforms for adding sensor packages needed for different applications, for example, most are equipped with high-resolution cameras and GPS sensors. The vantage point from an aerial platform dramatically improves the ability …

Perceptions Of Parental Care And Overprotection In Childhood: Influences On The Neurobiological Adaptation To Motherhood, Leah Grande

Electronic Theses and Dissertations

Recalled memories of caregiving in childhood are especially salient during the postpartum period and inform mothers’ conceptualization of her new parenting role. Positive perceptions of care received from one’s parents are related to improved maternal-infant bonding and positive parenting behaviors, whereas negative perceptions of care convey risk for maladaptive parenting. Few studies have investigated neural and biological mechanisms contributing to observed associations between childhood care and the adaptation to motherhood. The following studies address this gap by examining how perceptions of childhood parental care and overprotection are related to maternal behavior, oxytocin levels, and neural response. Methods: Perceived childhood maternal …

Dancing The Storm: Neurobiological Correlates Of Trauma-Related Psychopathology In Youth Resettled As Refugees, And The Efficacy Of Creative Arts And Movement Therapies To Address Trauma-Related Psychopathology, Lana Ruvolo Grasser

Wayne State University Dissertations

Exposure to stress and trauma activates key adaptive pathways, including the sympathetic adrenomedullary system and the immune system, which can result in long-term health impacts of trauma especially when experienced during sensitive developmental periods. Alterations in these systems are measurable through non-invasive methods including skin conductance response (SCR), fear potentiated startle (FPS), and inflammation. Research regarding the impact of trauma, and more specifically posttraumatic stress disorder, has primarily focused on adults, and there is a paucity of neurobiological research in displaced populations—like refugees—who may experience higher rates of trauma exposure and related psychopathology. The present study measured SCR to a …

Sentience In Decapods: Difficulties To Surmount, Michael L. Woodruff

Animal Sentience

In the target article Crump et al. present 8 criteria to assess whether decapods experience pain. Four of these -- sensory integration, motivational trade-offs, flexible self-protection, and associative learning -- could be used to assess sentience in general. In this commentary I discuss difficulties with using these criteria to provide evidence of sentience in decapods, particularly if this evidence is to change public opinion and policies. These difficulties are lack of evidence, the potential to eventually explain the neurobiological basis of the behaviors chosen as criteria, thereby eliminating any explanatory work for sentience, and the reluctance to bring animals that …

Investigating Anxiety-Like Behavior As A Non-Motor Side Effect Of Deep Brain Stimulation Of The Subthalamic Nucleus In A Parkinsonian Rat Model, Carter Mulder

All Graduate Theses, Dissertations, and Other Capstone Projects

Parkinson’s disease (PD) is estimated to impact nearly 10 million people globally and is estimated to increase in the future. PD is a progressive neurodegenerative disease that worsens through continuous cell death of dopaminergic neurons. This cell death can create motor symptoms such as bradykinesia, tremor, and muscular rigidity. Subthalamic nucleus deep brain stimulation, STN DBS, is a surgical intervention which places stimulating electrodes in the STN greatly improving motor symptoms. However, STN DBS has been reported to possibly influence non-motor symptoms such as anxiety both acutely and long-term, which decreases the quality of life for those with PD. We …

Parent-Prompted Dysregulation: Do Parents Serve As Cues For Dysregulation In Some Children?, Daniel Lee

Pitzer Senior Theses

Children occasionally encounter dysregulation when interacting with their parents in relatively neutral or positive scenarios. Given that the cause of dysregulation is usually relational, meaning it is often cued by someone who is seen to have power or control over the person, children could be particularly susceptible to dysregulation in the presence of their parents. However, when examining the existing literature, there appeared to be a lack of research and knowledge concerning this topic, with much of the literature focusing on the effect of child stressors on parental dysregulation. As a result, the term parent-prompted dysregulation was developed to refer …

Characterizing Cellular Stress, Hippocampal Function, And Behavior In A Novel Rat Model Of Alzheimer's Disease, Anne A. Schulman

Honors Theses

Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder that affects over 5 million individuals in the United States alone. While AD is primarily thought of as a disease that destroys neural networks required for memory recall and formation, AD also cause impairment in emotional regulation, cognitive flexibility, and executive function pathways. The cause of AD is unknown; however, the allele ApoE4 has been identified as a risk factor for the onset of AD. ApoE4 provides a valuable opportunity to study AD through animal models. This thesis utilized a human ApoE4 transgenic rat model (hApoE4) to investigate the biological and behavioral …

Double Trouble: The Development And Use Of A Novel Spatial Memory Task To Study Depression In A Female Rodent Model, Ekaterina L. Koelliker

Honors Theses

Preclinical rodent models of depression are important for improving our understanding of the behavioral and neurobiological implications of the disorder. However, the current behavioral assays used to assess depressive symptoms in rodents have substantial shortcomings; they are basic, test animals individually, and do not evaluate animals for extended periods. The primary goals of the present study, which was divided into two experiments, were to develop a novel task that could be used to study spatial memory and to apply the task to rodent models of depression. Both experiments used a circular arena with 10 identical jars to analyze the spatial …

Neural Correlates And Neuroanatomy Of Juvenile And Adult Contextual Fear Memory Retention, Natalie Odynocki

Legacy Theses & Dissertations (2009 - 2024)

AbstractFear is an evolutionarily conserved mechanism that allows an organism to discern potential harm and act accordingly by engaging in defensive behaviors. While fear is an adaptive response, dysregulation of fear by means of a traumatic event can lead to psychiatric conditions such as post-traumatic stress disorder (PTSD). Animal research using rodents in Pavlovian context fear conditioning experiments allows for the ability to study the underlying neural circuitry of threat-appropriate and aberrant fear learning and memory that may contribute to PTSD. However, despite reports that women are more than two times more likely to develop PTSD compared to men, the …

The Ecology And Evolution Of Human Reproductive Behavior, Kaylynne Glover

Theses and Dissertations--Biology

The complexity of human reproductive behavior has necessitated its examination through a variety of scientific disciplines, each focusing on specific elements of our biology, behavior, and society. However, this complexity also necessitates that we reintegrate the information learned from each discipline into a single framework, one rooted in the evolutionary principles that have shaped the development of all life on earth. In this dissertation, I use this framework to explore human reproductive behavior, with a particular focus on sexual coercion and fertility-mediated sexual behavior.

In Chapter 1, I introduce the approach taken in this document, identify several key limitations, and …

Investigation Of A Misophonia And Fluid Intelligence Relationship: Sound Spectrum Variation Impact On Fluid Intelligence Task Responses, Leslie Watson

Master's Theses or Doctor of Nursing Practice

ABSTRACT Studies of misophonia have not assessed the impact of music and sound complexity on intelligence in individuals with misophonia. Edelstein et al. (2013) have provided work which pools trigger sound characteristics including sound repetitiveness yet does not include a substantial music subcategory. Utilizing the Cattell–Horn–Carroll model of intelligence, the current study explores the nature of music and music complexity on fluid intelligence, as described by Sternberg (2012). The hypotheses for this study focused on the relationship that complexity and music might have with misophonia. The rate of misophonia in the Mechanical Turk population was hypothesized to be 20%. The …

The Evolution Of Quantitative Sensitivity, Margaret A H Bryer, Sarah E. Koopman, Jessica F. Cantlon, Steven T. Piantadosi, Evan L. Maclean, Joseph M. Baker, Michael J. Beran, Sarah M. Jones, Kerry E. Jordan, Salif Mahamane, Andreas Nieder, Bonnie M. Perdue, Friederike Range, Jeffrey R. Stevens, Masaki Tomonaga, Dorottya Ujfalussy, Jennifer Vonk

Jeffrey Stevens Publications

The ability to represent approximate quantities appears to be phylogenetically widespread, but the selective pressures and proximate mechanisms favouring this ability remain unknown. We analysed quantity discrimination data from 672 subjects across 33 bird and mammal species, using a novel Bayesian model that combined phylogenetic regression with a model of number psychophysics and random effect components. This allowed us to combine data from 49 studies and calculate the Weber fraction (a measure of quantity representation precision) for each species. We then examined which cognitive, socioecological and biological factors were related to variance in Weber fraction. We found contributions of phylogeny …

Does Having Siblings Affect Caretaking Responses To Infants?, Kaitlin Rose Duskin

Cal Poly Humboldt theses and projects

Infant facial cues affect a variety of caretaking-related responses in adults. These effects have primarily been explored as they relate to parental care, however infants receive care from others who are not their parents and it would be important for any caregiver, regardless of parental status, to respond to infant cues effectively. Because siblings often fulfill a caregiver role in the home, this study investigated whether having siblings, younger siblings in particular, influences the way in which adults respond to infant cues. Contrary to my predictions, the findings in this study indicate that having siblings does not influence how rewarding …

Does The Thatcher Effect Extend To Infant Faces?, Sarang Jew

Cal Poly Humboldt theses and projects

Decades of research on the mechanisms of face processing have demonstrated that humans rely heavily on configural processing strategies when viewing faces. However, this work has been done using almost exclusively adult facial stimuli. More recently, researchers have proposed that infant faces may elicit different neural activity and behavioral responses than adult faces. These observed differences may start at the very early stages of face processing (i.e., the structural encoding occurring within 200ms of seeing a face). However, no studies to date have explored potential differences in processing strategies used for infant faces compared to adult faces. The current study …

Hormonal Medications And Partner Odor Preferences, Jeffrey Lee Frederick

Cal Poly Humboldt theses and projects

The ability to recognize kin through the olfactory sense has important survival and evolutionary implications when choosing mates. Failing to recognize kin when making a choice of whom to mate with can lead to an increase in detrimental genetic outcomes in offspring. Previous studies have indicated that normally ovulating heterosexual women and men prefer the body odor of those with dissimilar immune systems than those with similar immune systems. The use of hormonal contraceptives has shown a preference for similar immune system odors. The current study examines whether the use of hormonal medications predicts preference for body odor. Importantly, this …

Black Hearts Matter: A Comparative Study Of Sociodemographic, Clinical, And Psychosocial Characteristics In Black And White Persons With Heart Failure, Hannah M Anderson Hughes

Theses and Dissertations

Heart failure (HF) is a chronic, progressive, debilitating illness that disproportionately affects Black individuals, often leading to poor quality of life (QOL). Various sociodemographic, clinical, and psychological characteristics are related to QOL in patients with HF. Because most studies do not include representative Black samples or report findings from racial subgroup analyses, these relationships and any existing racial differences are not well understood. The purpose of this descriptive, comparative study was to explore the relationships among sociodemographic, clinical, and psychological characteristics and QOL in patients with HF and to determine if there were racial differences between Black and White individuals. …

Integrating Interpersonal Neurobiology In Healthcare Leadership And Organizations, Lynn Redenbach

Antioch University Dissertations & Theses

Interpersonal Neurobiology (IPNB) is an interdisciplinary, science-based field that seeks to understand human reality including the nature of mind, brain, and relationships. IPNB has been used extensively by mental health practitioners as well as child development and parenting experts. While practitioners and scholars have described ways that IPNB can be used in leadership and organizations, there has been no systematic inquiry into the practical and phenomenological experience of this application. IPNB offers an alternative to dominant models of care and leading in healthcare settings and fields, which are characterized by disconnection, objectification, and separation. It offers a relationally centered approach …

Sleep And Cardiovascular Reactivity To An Acute Virtual Stressor, Alaina Grace Tiani

Graduate Theses, Dissertations, and Problem Reports (ETD)

Inappropriate response and magnitude of cardiovascular reactivity (CVR) to stress is a proposed mechanism through which environmental stressors are linked with poor cardiovascular health outcomes (Chida & Steptoe, 2010; Krantz & Manuck, 1984). Studies of reactivity to various laboratory tasks commonly control for factors known to influence CVR such as smoking, medication use, caffeine intake, and BMI; however, few have considered the influence of sleep on CVR. In order to determine whether sleep characteristics need to be assessed and considered in studies of CVR, this study aimed to examine the association between indices of sleep quality and the magnitude and …