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Full-Text Articles in Biological Psychology
The Effect Of Dopamine Blockade On Sensorimotor Gating In Social Phenotypes Of The African Cichlid Fish Astatotilapia Burtoni, Raymond A. Turco
The Effect Of Dopamine Blockade On Sensorimotor Gating In Social Phenotypes Of The African Cichlid Fish Astatotilapia Burtoni, Raymond A. Turco
Theses and Dissertations
We asked if blocking dopamine could improve implicit sensory gating deficits in a socially-defeated fish of a naturally-agonistic species. This study investigated the effects of dopamine D2R receptor antagonist metoclopramide on sensorimotor gating using a prepulse inhibition (PPI) paradigm in social phenotypes of male A. burtoni African cichlid fish.
A Genetically Informed Study Of Acute Threat Endophenotypes For Callous-Unemotional Traits, Ashlee A. Moore
A Genetically Informed Study Of Acute Threat Endophenotypes For Callous-Unemotional Traits, Ashlee A. Moore
Theses and Dissertations
Introduction. Callous-unemotional (CU) traits predict socially debilitating outcomes including Antisocial Personality Disorder and violent crime in adulthood. Despite significant research, the etiology of CU traits is not well understood. This dissertation incorporates genetic, physiological, neuroanatomical, and self-report measures to investigate the etiology of CU traits. Specifically, this project focuses on measures previously found to associate with impaired fear-processing observed in individuals high on CU. Brain morphometry for paralimbic regions of interest (ROIs) and electromyographic facial eyeblink reflex to startle and fear-potentiated startle probes were investigated as potential endophenotypes for CU traits. Methods. Two genetically informative (ages 9-20) twin samples ( …