Biological Psychology Commons^™

Evaluation Of Novel Κappa Opioid Agonists Alone And In Combination With D-Amphetamine On Locomotor Activity In Sprague-Dawley Rats Evaluation Of Novel Κappa Opioid Agonists Alone And In Combination With D-Amphetamine On Locomotor Activity In Sprague-Dawley Rats, Mary Melissa Peet

Dissertations

Stimulant abuse is a widespread problem that often leads to detrimental health and social consequences. Currently, there are no FDA-approved pharmacotherapies available as a treatment option for stimulant abuse or the prevention of relapse. Drugs targeting kappa opioid receptors (KOR) are under investigation as a potential pharmacotherapy. KOR agonists have been shown to modulate dopamine levels within brain reward pathways, thereby producing anti-addictive effects. Traditional KOR agonists unfortunately tend to produce untoward side effects, including sedation, limiting their therapeutic utility. Structurally different from traditional KOR agonists, salvinorin A (salvA) may produce less sedating effects while still exerting anti-addictive properties. SalvA …

Accessing Learning In The Adult Zebrafish With A Novel Associative Learning Task, David Joseph Jouandot Ii

Dissertations

The zebrafish (Danio rerio) is accepted in the developmental and genomic communities as a model organism. However, the capacity for the zebrafish as a behavioral model has yet to be fully acknowledged. The research presented provides evidence validating the novel task, aids in gaining a better understanding of the learning processes, and identifies individual differences. The novel associative learning task differs from any present well established behavioral model and lends itself to future development. The task provides the zebrafish community with a high output behavioral task which is readily replicated and allows one researcher to test between eight …

Effects Of Food Dispersion On Dominance Related Behaviors In Garnett's Bushbaby (Otolemur Garnettii)?, Kyle Daniel Edens

Dissertations

Socio-ecological theorists tie primate social structure diversity to variations in habitats within which primate species reside. This premise permits laboratory researchers to investigate specific factors that influence or relate to social structure formation and maintenance. The focus of the current investigation was three fold. We first aimed to determine the relationships between traditional and non-traditional behavioral measures of dominance, then evidence for dominance hierarchy formation was examined, and various hypotheses were tested to discern if adjustments in the foraging context altered social behaviors in Garnett’s bushbaby (Otolemur garnettii). It was determined that animals likely to displace conspecifics were …

The Relationship Between Suicide Ideation And Parasuicide: An Electrophysiological Investigation Using The Loudness Dependence Of Auditory Evoked Potential, Angelika Marsic

Dissertations

The loudness dependence of the auditory evoked potential (LDAEP) has been proposed as a promising valid and a non-invasive indicator of behaviorally relevant central 5-HT functioning. There is limited research on the utility of the LDAEP in discriminating individuals who engage in various degrees of suicidal behavior. The primary purpose of the present study was to examine if the LDAEP, as a measure of central serotonergic functioning, can be useful in distinguishing groups of individuals who: (a) solely experience suicidal ideation (SI group); (b) experience suicidal ideation and have engaged in deliberate self-harm acts (SH group); and (c) individuals with …

Short-Term Nicotine Abstinence And Decision Making, Gabriel D. Searcy

Dissertations

Research has shown that acute drug administration may affect impulsivity (i.e., choice for small, immediate rewards over large, delayed rewards) on laboratory delay-discounting tasks. Few studies have investigated how drug abstinence affects impulsivity. Investigating how drug abstinence affects impulsivity may be relevant to preventing relapse. Two previous studies have investigated the effects of short-term nicotine abstinence on impulsivity using delay-discounting tasks. The results were mixed, one study suggested that choices became more impulsive (i.e., delayed money was devalued) under nicotine deprivation. One goal of the present research was to further investigate how nicotine deprivation affects delay-discounting for money rewards. In …

Information Acquisition And Sociality Among Migratory Birds, Zoltán Németh

Dissertations

Information use is a key feature of adaptive behavior: the better informed an individual, the better it is able to adjust its behavior to meet the demands of a variable world. Therefore, most animals attempt to reduce environmental uncertainty by gathering information when it is available. However, tracking unpredictable ecological factors may carry costs as individuals invest valuable time and energy in the process of information acquisition. Social learning (i.e., use of social information inadvertently produced by other individuals) enables the individual to gain rapid and more complete assessment of its novel environment. This process may be particularly important for …

The Effects Of Dolphin Education Programs On Visitors' Conservation-Related Knowledge, Attitude And Behavior, Lance Joseph Miller

Dissertations

Zoological institutions typically exhibit dolphins in educational programs such as dolphin shows and interaction programs. The goal of these programs is to entertain visitors while increasing their conservation-related knowledge, attitude and behavior towards dolphins and the marine environment. The purpose of the current study was to examine dolphin shows and interaction programs in terms of their effectiveness in meeting these goals. A multi-institutional study was conducted at six different facilities throughout the United States. A repeated measures design was used to examine the knowledge, attitude and behavior of visitors before, immediately after and three months following participation in dolphin shows …

The Use Of Personality Assessments In Designing Environmental Enrichment For Garnett's Bushbabies (Otolemur Garnettii), Lauren Elizabeth Highfill

Dissertations

Recently the study of animal personality has become an important and credible topic of research and a number of studies have revealed personality traits in a variety of species. The consideration of individual animal personality traits is important for animal management and welfare. For example, ensuring inter-individual compatibility in group housing animals may serve to ensure the safety of the whole group. To date, no formal research has been conducted on whether the assessment of individual personality traits could be used as a tool for individualizing environmental enrichment interventions. The goal of environmental enrichment is to increase the rate of …

The Influence Of Species And Context On Human-Dolphin Interactions, Deirdre Breen Yeater

Dissertations

Anthropogenic activities pose a threat to marine mammals around the world. Cetaceans that use coastal waters are at particular risk for potential disturbances caused by vessel traffic and human swimmers. Although many cetacean species are found near the coast of Utila, Honduras, little is known about their behavior or the effects of anthropogenic activities on their behavior. Whether the presence of boats and human swimmers led to short-term changes in dolphin behavior was investigated for three commonly sighted species of dolphins; rough-toothed (Steno bredanensis), spinner (Stenalla longirostris), and bottlenose (Turslops truncatus). The dolphins' behavioral activities, with and without other boats …

Evaluation Of A School-Based Program Targeting Pediatric Asthma Self-Management Skills In An Urban Population, Dawn J. Dore-Stites

Dissertations

Asthma is the most commonly diagnosed chronic disorder in childhood and is linked with several problematic outcomes including frequent school absences, increased hospitalizations and decreased quality of life. Further, urban populations struggling with low socioeconomic status are disproportionately represented in prevalence statistics and suffer from increased functional morbidity relative to other children with asthma. These findings exist in the midst of largely effective pharmacological interventions.

Asthma self-management programs (SMPs) target several behaviors linked to improved outcomes and are often used as an adjunct to medication management. SMPs have been employed using a variety of techniques and treatment targets in a …

The Effects Of Gamma-Hydroxybutyrate On Response Acquisition, Sean Patrick Laraway

Dissertations

In the last 10 years, the use and abuse of the club drug gamma-hydroxybutyrate (GHB) has noticeably increased. Because GHB has only recently emerged as a drug of abuse, relatively little is known about the drug's behavioral effects, including its effects on learning. Therefore, the present study sought to characterize GHB's effects on rats' acquisition of a lever-press response using a two-lever, resetting/cancellation procedure. Under this procedure, responses on one ( reinforcement ) lever produced a single food pellet after a delay of 0, 20, or 40 s. Presses on the second ( cancellation ) lever during a delay interval …

Assessment Of The Discriminative Stimulus Effects Of (±)-3,4-Methylenedioxymethamphetamine (Mdma, "Ecstasy") And (+Lysergic Add Diethylamide (Lsd) In A Three-Lever Drug Discrimination Procedure, Amy K. Goodwin

Dissertations

(±)3,4-Methylenedioxymethamphetamine (MDMA) is a common drug of abuse known as "ecstasy." Currently, MDMA is classified into the traditional drug classes as both a "stimulant" and a "hallucinogen" because it is reported to share both subjective and physiological properties of both classes. MDMA is thought to produce its psychoactive effects by acting as both a serotonin and a dopamine agonist. However, the relative importance of the serotonin and dopamine neurotransmitter systems in mediating the stimulus properties of MDMA remains unclear.

The drug discrimination assay is used to classify drugs as "similar" or "dissimilar," as well as to examine underlying neurochemical changes …